33 research outputs found

    Szenarienkarten Wassererosion in Sachsen: Erarbeitung und Bereitstellung von Szenarienkarten Wassererosion mit EROSION-3D für Ackerflächen Sachsens

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    Mithilfe des Modells EROSION-3D wurden für sämtliche Ackerflächen Sachsens Erosionsszenarienkarten erstellt. Der vorliegende Band der Schriftenreihe dient der Dokumentation der Modellierungen. Fachnutzer und interessierte Privatpersonen erhalten so die Möglichkeit, sich mit der Methodik und den zugrundeliegenden Modellannahmen vertraut zu machen. Die Szenarienkarten selbst sind im Portal iDA abrufbar in der Rubrik „Landwirtschaft“ > „Erosionsgefährdung Landwirtschaftliche Nutzflächen“ > „Erosionsszenarienkarten Modell EROSION 3D“. Redaktionsschluss: 31.08.202

    Влияние параметров торцовой фрезы на характер обработанной поверхности

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    Материалы ХI Международной науч.-техн. конф. студентов, магистрантов и аспирантов [28-29 апреля 2011 г., г. Гомель]. - Гомель, 2011

    Can core-surface flow models be used to improve the forecast of the Earth's main magnetic field?

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    [1] Geomagnetic main field models used for navigation are updated every 5 years and contain a forecast of the geomagnetic secular variation for the upcoming epoch. Forecasting secular variation is a difficult task. The change of the main magnetic field is thought to be principally due to advection of the field by flow at the surface of the outer core on short timescales and when large length scales are considered. With accurate secular variation (SV) and secular acceleration (SA) models now available from new satellite missions, inverting for the flow and advecting it forward could lead to a more accurate prediction of the main field. However, this scheme faces two significant challenges. The first arises from the truncation of the observable main field at spherical harmonic degree 13. This can however be handled if the true core flow is large scale and has a rapidly decaying energy spectrum. The second is that even at a given single epoch the instantaneous SV and SA cannot simultaneously be explained by a steady flow. Nevertheless, we find that it may be feasible to use flow models for an improved temporal extrapolation of the main field. A medium-term (≈10 years) hindcast of the field using a steady flow model outperforms the usual extrapolation using the presently observed SV and SA. On the other hand, our accelerated, toroidal flow model, which explains a larger portion of the observed average SA over the 2000–2005 period, fails to improve both the short-term and medium-term hindcasts of the field. This somewhat paradoxical result is related to the occurrence of so-called geomagnetic jerks, the still poorly known dynamical nature of which remains the main obstacle to improved geomagnetic field forecasts

    Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

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    BACKGROUND: The diagnostic and pathophysiological relevance of antibodies to aquaporin-4 (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been intensively studied. However, little is known so far about the clinical impact of AQP4-Ab seropositivity. OBJECTIVE: To analyse systematically the clinical and paraclinical features associated with NMO spectrum disorders in Caucasians in a stratified fashion according to the patients' AQP4-Ab serostatus. METHODS: Retrospective study of 175 Caucasian patients (AQP4-Ab positive in 78.3%). RESULTS: Seropositive patients were found to be predominantly female (p 1 myelitis attacks in the first year were identified as possible predictors of a worse outcome. CONCLUSION: This study provides an overview of the clinical and paraclinical features of NMOSD in Caucasians and demonstrates a number of distinct disease characteristics in seropositive and seronegative patients

    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

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    In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field

    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

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    Szenarienkarten Wassererosion in Sachsen: Erarbeitung und Bereitstellung von Szenarienkarten Wassererosion mit EROSION-3D für Ackerflächen Sachsens

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    Mithilfe des Modells EROSION-3D wurden für sämtliche Ackerflächen Sachsens Erosionsszenarienkarten erstellt. Der vorliegende Band der Schriftenreihe dient der Dokumentation der Modellierungen. Fachnutzer und interessierte Privatpersonen erhalten so die Möglichkeit, sich mit der Methodik und den zugrundeliegenden Modellannahmen vertraut zu machen. Die Szenarienkarten selbst sind im Portal iDA abrufbar in der Rubrik „Landwirtschaft“ > „Erosionsgefährdung Landwirtschaftliche Nutzflächen“ > „Erosionsszenarienkarten Modell EROSION 3D“. Redaktionsschluss: 31.08.202

    Szenarienkarten Wassererosion in Sachsen: Erarbeitung und Bereitstellung von Szenarienkarten Wassererosion mit EROSION-3D für Ackerflächen Sachsens

    No full text
    Mithilfe des Modells EROSION-3D wurden für sämtliche Ackerflächen Sachsens Erosionsszenarienkarten erstellt. Der vorliegende Band der Schriftenreihe dient der Dokumentation der Modellierungen. Fachnutzer und interessierte Privatpersonen erhalten so die Möglichkeit, sich mit der Methodik und den zugrundeliegenden Modellannahmen vertraut zu machen. Die Szenarienkarten selbst sind im Portal iDA abrufbar in der Rubrik „Landwirtschaft“ > „Erosionsgefährdung Landwirtschaftliche Nutzflächen“ > „Erosionsszenarienkarten Modell EROSION 3D“. Redaktionsschluss: 31.08.202
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