SDN-based Virtual Machine Management for Cloud Data Centers

Software-Defined Networking (SDN) is an emerging paradigm to logically centralize the network control plane and automate the configuration of individual network elements. At the same time, in Cloud Data Centers (DCs), even though network and server resources converge over the same infrastructure and typically under a single administrative entity, disjoint control mechanisms are used for their respective management. In this paper, we propose a unified server-network control mechanism for converged ICT environments. We present a SDN-based orchestration framework for live Virtual Machine (VM) management where server hypervisors exploit temporal network information to migrate VMs and minimize the network-wide communication cost of the resulting traffic dynamics. A prototype implementation is presented and Mininet is used to evaluate the impact of diverse orchestration algorithms

SDN-based Virtual Machine Management for Cloud Data Centers

Software-Defined Networking (SDN) is an emerging paradigm to logically centralize the network control plane and automate the configuration of individual network elements. At the same time, in Cloud Data Centers (DCs), although network and server resources are collocated and managed by a single administrative entity, disjoint control mechanisms are used for their respective management. In this article, we propose a unified server-network resource management for such converged Information and Communication Technology (ICT) environments. We present a SDN-based orchestration framework for live Virtual Machine (VM) management that exploits temporal network information to migrate VMs and minimize the network-wide communication cost of the resulting traffic dynamics. A prototype implementation is presented, and a Cloud DC testbed is used to evaluate the impact of diverse orchestration algorithms. Our live VM management has been shown to reduce the network-wide communication cost, especially for the high-cost and congestionprone core and aggregation layers of the DC. Our results show an increase in network-wide throughput by over 6 times, as well as over 70% communication cost reduction by migrating less than 50% of the VMs

Effect of impurities and processing on silicon solar cells. Volume 1: Characterization methods for impurities in silicon and impurity effects data base

Two major topics are treated: methods to measure and evaluate impurity effects in silicon and comprehensive tabulations of data derived during the study. Discussions of deep level spectroscopy, detailed dark I-V measurements, recombination lifetime determination, scanned laser photo-response, conventional solar cell I-V techniques, and descriptions of silicon chemical analysis are presented and discussed. The tabulated data include lists of impurity segregation coefficients, ingot impurity analyses and estimated concentrations, typical deep level impurity spectra, photoconductive and open circuit decay lifetimes for individual metal-doped ingots, and a complete tabulation of the cell I-V characteristics of nearly 200 ingots

Clinicians’ Perceptions of Telemedicine for Conducting Family Conferences Prior to Transfer to a Tertiary Care Center Intensive Care Unit

Objectives: Critically ill patients are often transferred from rural to tertiary care medical centres for further higher levels of care. The transportation process may delay family conferences during which prognosis and goals of care are discussed. These conferences typically occur when family members meet the treating physicians for the first time in person after transport. Telemedicine is a tool that may be used to bridge this gap in communication by enabling these family conferences before transport. There are no data on perceptions of telemedicine used in this setting. We conducted a qualitative study assessing provider perceptions regarding the use of telemedicine for conducting family conferences prior to transport. Methods: Critical care physicians and nurses were invited to view an educational video demonstrating the process of conducting a family conference via telemedicine. Immediately following viewing of the video, physicians and nurses filled out an open-ended questionnaire regarding their thoughts and perceptions of the video and the telemedicine family conference approach. Results: There was a 68% response rate to the surveys. Responses were categorised into two major themes: benefits and barriers. Within the theme of benefits, three sub-themes were identified: satisfaction, knowledge and quality of care. We identified four domains within the theme of barriers: time, perception, technology and logistics. Conclusions: Respondents believe that there may be several benefits including increased satisfaction, improved communication and empowerment of families by dissemination of knowledge. Barriers to the use of this intervention identified include costs, time, technology and negative perceptions of the telemedicine conference

Leukotriene C4 biosynthesis in isolated August rat peritoneal leukocytes

The mixed leukocyte population obtained from the peritoneum of the August rat is a potentially important experimental model of inherent eosinophilia that has not been well characterized. In the present study, isolated cell preparations generated a concentration-dependent release of leukotriene (LT) C4 when exposed to the Ca2+ ionophore A23187, reaching maximal stimulation at 5.0 μM. This response was inhibited by the 5-lipoxygenase activating protein antagonist MK-886 (0.1 μM), nominally Ca2+ and Mg2+-free incubation media and by activation of protein kinase C via phorbol 12-myristate 13-acetate (50 nM). These findings establish a model system for investigating LTC4 profiles contingent with innate peritoneal eosinophilia and are consistent with the hypothesis that cellular LTC4 biosynthesis is phosphoregulated

Recognition of envelope and tat protein synthetic peptide analogs by HIV positive sera or plasma

AbstractA series of synthetic peptides corresponding to segments of HIV encoded proteins were selected using criteria described by Welling et al. [(1985) FEBS Lett. 188, 215]. Synthetic peptide analogs to gpl20 (2–13), (55–65), gp41 (582–596) (659–670) and tatIII (71–83) were recognized by 41–67% of sera or plasma from individuals known to be infected with HIV on the basis of virus isolation or Western blot screening. The peptide which reacted with most sera or plasma was gp41 (582–596), a conserved region in the transmembrane glycoprotein. An extended peptide analog, gp41 (579–599), tested against the same samples showed almost 100% reactivity, confirming independent studies identifying a highly immunodominant region of gp41. There was an unexpected high prevalence of antibodies (52%) to the tatIII peptide

'Selling it as a holistic health provision and not just about condoms ?' Sexual health services in school settings: current models and their relationship with sex and relationships education policy and provision

In this article we discuss the findings from a recent study of UK policy and practice in relation to sexual health services for young people, based in - or closely linked with - schools. This study formed part of a larger project, completed in 2009, which also included a systematic review of international research. The findings discussed in this paper are based on analyses of interviews with 51 service managers and questionnaire returns from 205 school nurses. Four themes are discussed. First, we found three main service permutations, in a context of very diverse and uneven implementation. Second, we identified factors within the school context that shaped and often constrained service provision; some of these also have implications for sex and relationships education (SRE). Third, we found contrasting approaches to the relationship between SRE input and sexual health provision. Fourth, we identified some specific barriers that need to be addressed in order to develop 'young people friendly' services in the school context. The relative autonomy available to school head teachers and governors can represent an obstacle to service provision - and inter-professional collaboration - in a climate where, in many schools, there is still considerable ambivalence about discussing 'sex' openly. In conclusion, we identify areas worthy of further research and development, in order to address some obstacles to sexual health service and SRE provision in schools