The Ursinus Weekly, February 22, 1965

The weekend that was: First annual winter weekend a winner • Y plans second annual art show and awards • TW3 presentation demands humor, wit and intelligence of audience as well as players • Sophomore men again eligible for St. Andrew\u27s grant • Weekly interviews Richard Richter, Alumni Secretary • UC produces no winners in bridge tourney • UCC workers report Summer project in South • PSEA hears Ridge speak on trends in education • All college rally in volleyball, badminton planned • Editorial: Semi-concentrated study • Victory in South Vietnam: Is it worth the price? • Letters to the editor • How to get an A without really studying • New customs program pitted against the old • Snellbelles win two, record unblemished • Matmen win twice; Up record 5-2 • Intramurals: 5 teams unbeaten • Bears split two, season stands 7-8: Crush Hopkins, lose to Drexel • Complicated plot for simple story in The Spy • Ursinus history • Greek gleanings • Howard succeeds Quinn as Ursinus tennis coach • JB collapses second time for want of God • Zucker elected to ACLU Board • Pre-med societyhttps://digitalcommons.ursinus.edu/weekly/1240/thumbnail.jp

The Ursinus Weekly, December 14, 1964

Enthusiastic Pooh audience hears A. A. Milne children\u27s play: Matinee by Curtain Club • Faculty accepts senate approved hours change • Chorus and soloists usher Christmas season with 27th annual Messiah: Students attend full afternoon rehearsal • Christmas activities fill last week of 1964: Robin Roberts at MSGA banquet; Women\u27s banquet; Dorms hold open house; Mrs. Helfferich\u27s party; Candlelight communion; Christmas dance • Greeks hosts to orphans in area parties • Richard P. Richter accepts duties as alumni secretary • Frosh plan cool Ice palace \u2765 • Bridge tourney on UC campus • Spirit of Christmas present • B-ball team splits two close ones, 60-59 and 70-71: Sloppiness and apathy big factors • ZX leads v-ball; Demas second • Wrestling team looks strong • UC girl confesses in dial-a-bride • Letters to the editor • Greek gleanings • Ursinus kitchen food preparation exposedhttps://digitalcommons.ursinus.edu/weekly/1237/thumbnail.jp

The Ursinus Weekly, January 11, 1965

Football players receive awards at banquet: Tony Motto gets All-ECAC • Ursinus to send delegation to Model UN • Weekly names Sam Walker sports editor • Faculty Forum to present concert, lecture recital: 20th century American music, subject • Three placed in teaching positions • Pre-meds to hear two Sacred Heart pathologists • World\u27s Fair invites college talent to perform • Pi Nu Epsilon, music fraternity, initiates eight • Norristown man named to vacancy in Treas. Office • Good band, decorations add to great TG dance • The best TV show in the world • Editorial: Our large small college • Bob Dylan: Alone and indifferent • J. D. Salinger writes for The Ursinus Weekly • Anthem, a warning to society • The Doanes report on teaching in the South • Bears drop two, F&M-Swarthmore; Troster\u27s thirty points rock PMC • Matmen drop opener to Del. • Soccer team puts three on All-MAC • Y Commission sponsors film on discrimination • Greek gleanings • Letters to the editor • Kaffee Klatsch debates Negro block bustinghttps://digitalcommons.ursinus.edu/weekly/1238/thumbnail.jp

The Ursinus Weekly, October 19, 1964

Bethany director to be awarded honorary degree • Moss and Creager review ministry in lively discussion • Dr. Charles D. Mattern dies suddenly at home: Funeral to be Tuesday • Young politicians debate national partisan issues: Campus voting follows, Wednesday • Football game, reception to highlight Parents\u27 Day • A word from the Dean • Zuckers to appear with Rutgers choir at Carnegie Hall • Agency begins second year, requests support • Projected literary magazine plans liberal editorial policy • Editorial: In memoriam • Bomberger texts survive intact • Individualism - Iran style • Goldwater\u27s policies: What are they? • Letters to the editor • Wilkes overpowers thin UC squad, 42-13 • Dorms race tight: Frats play to wire • Soccermen bow in third game • Varsity wins first game, JVs continue winning ways: Rosemont beaten, skein at 8 straight; Rain no handicap, Wilson falls 2-1 • Prison expert reviews field • Regional speaker addresses PSEA • Greek gleaningshttps://digitalcommons.ursinus.edu/weekly/1230/thumbnail.jp

25th annual computational neuroscience meeting: CNS-2016

The same neuron may play different functional roles in the neural circuits to which it belongs. For example, neurons in the Tritonia pedal ganglia may participate in variable phases of the swim motor rhythms [1]. While such neuronal functional variability is likely to play a major role the delivery of the functionality of neural systems, it is difficult to study it in most nervous systems. We work on the pyloric rhythm network of the crustacean stomatogastric ganglion (STG) [2]. Typically network models of the STG treat neurons of the same functional type as a single model neuron (e.g. PD neurons), assuming the same conductance parameters for these neurons and implying their synchronous firing [3, 4]. However, simultaneous recording of PD neurons shows differences between the timings of spikes of these neurons. This may indicate functional variability of these neurons. Here we modelled separately the two PD neurons of the STG in a multi-neuron model of the pyloric network. Our neuron models comply with known correlations between conductance parameters of ionic currents. Our results reproduce the experimental finding of increasing spike time distance between spikes originating from the two model PD neurons during their synchronised burst phase. The PD neuron with the larger calcium conductance generates its spikes before the other PD neuron. Larger potassium conductance values in the follower neuron imply longer delays between spikes, see Fig. 17.Neuromodulators change the conductance parameters of neurons and maintain the ratios of these parameters [5]. Our results show that such changes may shift the individual contribution of two PD neurons to the PD-phase of the pyloric rhythm altering their functionality within this rhythm. Our work paves the way towards an accessible experimental and computational framework for the analysis of the mechanisms and impact of functional variability of neurons within the neural circuits to which they belong

Identification of members of the Wnt signaling pathway in the embryonic pituitary gland

Prop1 is one of several transcription factors important for the development of the pituitary gland. Downstream targets of PROP1 and other critical pituitary transcription factors remain largely unknown. We have generated a partial expression profile of the developing pituitary gland containing over 350 transcripts, using cDNA subtractive hybridization between Prop1 df/df and wild-type embryonic pituitary gland primordia. Numerous classes of genes including transcription factors, membrane associated molecules, and cell cycle regulators were identified in this study. Of the transcripts, 34% do not have sequence similarity to known genes, but are similar to ESTs, and 4% represent novel sequences. Pituitary gland expression of a number of clones was verified using in situ hybridization.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/42122/1/335-12-11-843_10120843.pd