Contributions of the development of personal learning environments by students of a mooc

The study arises from the need to evaluate training options available to all, as well as technological environments that allow acquiring and developing self-regulatory skills. The general objective is to determine what are the contributions in the learning, and the use frequency of Web 2.0 tools in the students of an Open and Online Massive Course (MOOC) that develop a Personal Learning Environment (PLE). A parametric and nonparametric quasi-experimental design was applied in paired and unpaired groups of a non-probabilistic sample formed by two groups of students enrolled in a course, where the results of the learning of the contents of the course were contrasted, and the frequency of the use of technological tools, among a group of MOOC students to whom the learning was directed and another group that self-directed their learning using a PLE formed by Web 2.0 tools. It is shown that the results of the statistical contrasts are not significant on the part of the students of the group that self-directed their learning, with respect to the group that followed the instructions of the teacher all the time through a platform, but it is highlighted that the students taking an active and autonomous role, achieved to learn the contents and acquire skills in the use of technological toolsEl estudio surge de la necesidad de evaluar opciones de capacitación al alcance de todos, así como de entornos tecnológicos que permitan adquirir y desarrollar habilidades de autorregulación. El objetivo general es determinar cuáles son las aportaciones en el aprendizaje y en la frecuencia de uso de herramientas Web 2.0 en los alumnos de un Curso Masivo Abierto y en Línea (MOOC) que desarrollan un Entorno Personal de Aprendizaje (PLE). Se aplicó un diseño cuasi-experimental paramétrico y no paramétrico en grupos apareados y no apareados, de una muestra no probabilística formada por dos grupos de alumnos inscritos en un curso, donde se contrastaron los resultados del aprendizaje de los contenidos del curso y la frecuencia de uso de herramientas tecnológicas, entre un grupo de alumnos del MOOC al que se dirigió el aprendizaje y otro grupo que autodirigió su aprendizaje haciendo uso de un PLE formado por herramientas Web 2.0. Se muestra que los resultados de los contrastes estadísticos no son significativos por parte de los alumnos del grupo que autodirigió su aprendizaje, con respecto del grupo que siguió todo el tiempo las instrucciones del docente por medio de una plataforma, pero se resalta que los alumnos tomando un rol activo y autónomo, lograron por sí solos el aprendizaje de los contenidos y la adquisición de habilidades en el uso de herramientas tecnológica

Tecnología educativa. Propuestas para la implementación en el contexto escolar

Tecnología educativa. Propuesta para la implementación en el contexto escolar aporta a la comunidad educativa un panorama actual sobre tópicos referentes al tema de las tecnologías de la información y comunicación como alternativas de uso y aplicación de herramientas de software libre en el contexto escolar

Performance of standardised colposcopy to detect cervical precancer and cancer for triage of women testing positive for human papillomavirus : results from the ESTAMPA multicentric screening study

Correspondence to: Dr Joan Valls, Early Detection, Prevention and Infections Branch, International Agency for Research on Cancer, Lyon 69366, France. [email protected]. Colposcopy, currently included in WHO recommendations as an option to triage human papillomavirus (HPV)-positive women, remains as the reference standard to guide both biopsy for confirmation of cervical precancer and cancer and treatment approaches. We aim to evaluate the performance of colposcopy to detect cervical precancer and cancer for triage in HPV-positive women. Methods. This cross-sectional, multicentric screening study was conducted at 12 centres (including primary and secondary care centres, hospitals, laboratories, and universities) in Latin America (Argentina, Bolivia, Colombia, Costa Rica, Honduras, Mexico, Paraguay, Peru, and Uruguay). Eligible women were aged 30–64 years, sexually active, did not have a history of cervical cancer or treatment for cervical precancer or a hysterectomy, and were not planning to move outside of the study area. Women were screened with HPV DNA testing and cytology. HPV-positive women were referred to colposcopy using a standardised protocol, including biopsy collection of observed lesions, endocervical sampling for transformation zone (TZ) type 3, and treatment as needed. Women with initial normal colposcopy or no high-grade cervical lesions on histology (less than cervical intraepithelial neoplasia [CIN] grade 2) were recalled after 18 months for another HPV test to complete disease ascertainment; HPV-positive women were referred for a second colposcopy with biopsy and treatment as needed. Diagnostic accuracy of colposcopy was assessed by considering a positive test result when the colposcopic impression at the initial colposcopy was positive minor, positive major, or suspected cancer, and was considered negative otherwise. The main study outcome was histologically confirmed CIN3+ (defined as grade 3 or worse) detected at the initial visit or 18-month visit. Findings. Between Dec 12, 2012, and Dec 3, 2021, 42 502 women were recruited, and 5985 (14·1%) tested positive for HPV. 4499 participants with complete disease ascertainment and follow-up were included in the analysis, with a median age of 40·6 years (IQR 34·7–49·9). CIN3+ was detected in 669 (14·9%) of 4499 women at the initial visit or 18-month visit (3530 [78·5%] negative or CIN1, 300 [6·7%] CIN2, 616 [13·7%] CIN3, and 53 [1·2%] cancers). Sensitivity was 91·2% (95% CI 88·9–93·2) for CIN3+, whereas specificity was 50·1% (48·5–51·8) for less than CIN2 and 47·1% (45·5–48·7) for less than CIN3. Sensitivity for CIN3+ significantly decreased in older women (93·5% [95% CI 91·3–95·3] in those aged 30–49 years vs 77·6% [68·6–85·0] in those aged 50–65 years; p<0·0001), whereas specificity for less than CIN2 significantly increased (45·7% [43·8–47·6] vs 61·8% [58·7–64·8]; p<0·0001). Sensitivity for CIN3+ was also significantly lower in women with negative cytology than in those with abnormal cytology (p<0·0001). Interpretation. Colposcopy is accurate for CIN3+ detection in HPV-positive women. These results reflect ESTAMPA efforts in an 18-month follow-up strategy to maximise disease detection with an internationally validated clinical management protocol and regular training, including quality improvement practices. We showed that colposcopy can be optimised with proper standardisation to be used as triage in HPV-positive women.Consejo Nacional de Ciencia y TecnologíaPrograma Paraguayo para el Desarrollo de la Ciencia y Tecnología. Proyectos de investigación y desarrollo14-INV-036PINV18-25

Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol

Q1Q1Introduction Human papillomavirus (HPV) testing is replacing cytology in primary screening. Its limited specificity demands using a second (triage) test to better identify women at high-risk of cervical disease. Cytology represents the immediate triage but its low sensitivity might hamper HPV testing sensitivity, particularly in low-income and middle-income countries (LMICs), where cytology performance has been suboptimal. The ESTAMPA (EStudio multicéntrico de TAMizaje y triaje de cáncer de cuello uterino con pruebas del virus del PApiloma humano; Spanish acronym) study will: (1) evaluate the performance of different triage techniques to detect cervical precancer and (2) inform on how to implement HPV-based screening programmes in LMIC. Methods and analysis Women aged 30–64 years are screened with HPV testing and Pap across 12 study centres in Latin America. Screened positives have colposcopy with biopsy and treatment of lesions. Women with no evident disease are recalled 18 months later for another HPV test; those HPV-positive undergo colposcopy with biopsy and treatment as needed. Biological specimens are collected in different visits for triage testing, which is not used for clinical management. The study outcome is histological high-grade squamous intraepithelial or worse lesions (HSIL+) under the lower anogenital squamous terminology. About 50 000 women will be screened and 500 HSIL+ cases detected (at initial and 18 months screening). Performance measures (sensitivity, specificity and predictive values) of triage techniques to detect HSIL+ will be estimated and compared with adjustment by age and study centre. Ethics and dissemination The study protocol has been approved by the Ethics Committee of the International Agency for Research on Cancer (IARC), of the Pan American Health Organisation (PAHO) and by those in each participating centre. A Data and Safety Monitoring Board (DSMB) has been established to monitor progress of the study, assure participant safety, advice on scientific conduct and analysis and suggest protocol improvements. Study findings will be published in peer-reviewed journals and presented at scientific meetings. Trial registration number NCT01881659Revista Internacional - Indexad

interfluences

Recopila y registra obras compuestas, transcritas y o intervenidas por el maestro Samuel Bedoya SánchezIt collects and registers works composed, transcribed and or intervened by the maestro Samuel Bedoya Sánche

The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas

Indigenous populations, including in those in Mexico are underrepresented in genetic studies. Here, the authors perform a population genetics study of indigenous peoples in Mexico to explore demographic histories of the region in the context of geography and cultural influences

Compilación de Proyectos de Investigación desde el año 2003 al 2012

Listado de Proyectos de investigación de UPIICSA desde 2003 a 201

Compilación de Proyectos de Investigacion de 1984-2002

Instituto Politecnico Nacional. UPIICS