Ontology Visualization Tool for Indexing DICOM Structured Reporting (SR) Documents.

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Usability via a Visualization Tool for the Semantic Indexing of Medical Reports (DICOM SR)

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Unification d'ontologies hétérogènes pour l'indexation sémantique de compte rendu standardisé d'examens du patient

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Volumetric mass transfer coefficient and hydrodynamic study of a new self-inducing turbine

International audienceThe self-inducing turbines are among mobile agitations which present a very interesting potential in terms of energy in the field of wastewater treatment by activated sludge. Often, the reactions involved in this type of contactors are limited by the gas-liquid mass transfer. The objective of this experimental work is the determination of the oxygenation capacity of a new self-inducing turbine, a holed hollow cylinder, having a thickness of W = 1.5 cm and a diameter D = 9 cm, with 6 holes having a diameter of 0.5 cm each. During this experimental work, we evaluated the volumetric mass transfer coefficient k(L)a, which is directly related to the oxygenation capacity (OC) and this for various rotational speeds of the turbine as well as for various submergences. We finally succeeded to find an empirical correlation for our new self inducing turbine. The most common method used to estimate experimentally the coefficient k(L)a is the technique of dynamic oxygenation and deoxygenation. We finally concluded that this new turbine had a satisfying aeration capacity, which increases with the increase of the rotational speed, and decreases when increasing the submergence of the impeller. (C) 2013 Elsevier Ltd. All rights reserved

Volumetric mass transfer coefficient and hydrodynamic study of a new self-inducing turbine

International audienceThe self-inducing turbines are among mobile agitations which present a very interesting potential in terms of energy in the field of wastewater treatment by activated sludge. Often, the reactions involved in this type of contactors are limited by the gas-liquid mass transfer. The objective of this experimental work is the determination of the oxygenation capacity of a new self-inducing turbine, a holed hollow cylinder, having a thickness of W = 1.5 cm and a diameter D = 9 cm, with 6 holes having a diameter of 0.5 cm each. During this experimental work, we evaluated the volumetric mass transfer coefficient k(L)a, which is directly related to the oxygenation capacity (OC) and this for various rotational speeds of the turbine as well as for various submergences. We finally succeeded to find an empirical correlation for our new self inducing turbine. The most common method used to estimate experimentally the coefficient k(L)a is the technique of dynamic oxygenation and deoxygenation. We finally concluded that this new turbine had a satisfying aeration capacity, which increases with the increase of the rotational speed, and decreases when increasing the submergence of the impeller. (C) 2013 Elsevier Ltd. All rights reserved

Performance of UASB reactor treating waste activated sludge: Effect of electro-chemical disintegration on the anaerobic microbial population structure and abundance

The electro-Fenton (EF) disintegration using iron electrodes was performed for the pretreatment of waste activated sludge (WAS). The effect of this electro-chemical pretreatment on anaerobic digestion (AD) performance and microbial population structure was studied. An improvement of biodegradability and bioaccessibility of organic matter was demonstrated. AD of pretreated WAS in an up-flow anaerobic sludge blanket reactor (UASB) resulted to an increase of biogas production by 60 % compared to control reactor without disintegration. PCR-DGGE and real-time qPCR analyses showed that the high abundance of bacteria and the coexistence of Coprothermobacter in the UASB digestate fed with disintegrated sample established a stable bacterial association which is in line with the AD performance. Besides, the increased number of methanogens along the process allowed the improvement of methane production in comparison to control reactor

Using KASP technique to screen LRRK2 G2019S mutation in a large Tunisian cohort

Abstract Background In North African populations, G2019S mutation in LRRK2 gene, encoding for the leucine-rich repeat kinase 2, is the most prevalent mutation linked to familial and sporadic Parkinson’s disease (PD). Early detection of G2019S by fast genetic testing is very important to guide PD’s diagnosis and support patients and their family caregivers for better management of their life according to disease’s evolution. Methods In our study, a genetic PD’s diagnosis tool was developed for large scale genotyping using Kompetitive Allele Specific PCR (KASP) technology. We investigated G2019S’s frequency in 250 Tunisian PD patients and 218 controls. Results We found that 33.6% of patients and 1.3% of controls were carriers. Demographic characteristics of patients with G2019S had no differences compared with non-carrier patients. Thereby, we could emphasize the implication of G2019S in PD without any distinctive demographic factors in the studied cohort. Sixty patients out of 250 were genotyped using Taqman assay and Sanger sequencing. The genotyping results were found to be concordant with KASP assay. Conclusions The G2019S mutation frequency in our cohort was similar to that reported in previous studies. Comparing to Taqman assay and Sanger sequencing, KASP was shown to be a reliable, time and cost effective genotyping assay for routine G2019S screening in genetic testing laboratories

Genome sequence and Carbohydrate Active Enzymes (CAZymes) repertoire of the thermophilic Caldicoprobacter algeriensis TH7C1T

11 p.-3 fig.-3 tab.Background: Omics approaches are widely applied in the field of biology for the discovery of potential CAZymes including whole genome sequencing. The aim of this study was to identify protein encoding genes including CAZymes in order to understand glycans-degrading machinery in the thermophilic Caldicoprobacter algeriensis TH7C1T strain.Results: Caldicoprobacter algeriensis TH7C1T is a thermophilic anaerobic bacterium belonging to the Firmicutes phylum, which grows between the temperatures of 55 °C and 75 °C. Next generation sequencing using Illumina technology was performed on the C. algeriensis strain resulting in 45 contigs with an average GC content of 44.9% and a total length of 2,535,023 bp. Genome annotation reveals 2425 protein-coding genes with 97 ORFs coding CAZymes. Many glycoside hydrolases, carbohydrate esterases and glycosyltransferases genes were found linked to genes encoding oligosaccharide transporters and transcriptional regulators; suggesting that CAZyme encoding genes are organized in clusters involved in polysaccharides degradation and transport. In depth analysis of CAZomes content in C. algeriensis genome unveiled 33 CAZyme gene clusters uncovering new enzyme combinations targeting specific substrates.Conclusions: This study is the first targeting CAZymes repertoire of C. algeriensis, it provides insight to the high potential of identified enzymes for plant biomass degradation and their biotechnological applications.This work was supported by the Tunisian Ministry of Higher Education and Scientific Research (contract program LBMIE-CBS, code: LR15CBS06) and the Algerian-Tunisian R&I Cooperation for the Mixed Laboratories of Scientific Excellence 2021–2024 (Hydro-BIOTECH, code LABEX/TN/DZ/21/01). The high throughput sequencing, assembly and annotation work was supported by the IBISBA1.0 H2020 project 730976 (https://www.ibisba.eu/) at its CSIC Cell Factory node.Peer reviewe