1,614 research outputs found

    Projeto de desenvolvimento da marca gráfica para a profissional terapeuta autônoma Rosane Sommer

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    PCC(graduação) - Universidade Federal de Santa Catarina. Centro de Comunicação e Expressão. Design.Trata-se do relatório de desenvolvimento e apresentação dos resultados do Projeto de Conclusão de Curso (PCC) de graduação em Design, no contexto da área de Gestão do Design Gráfico. O foco do projeto foi sobre o desenho da assinatura visual da profissional Rosane Sommer, que identifica, representa e qualifica uma terapeuta autônoma que presta serviços no âmbito das terapias alternativas. O processo de pesquisa sobre a identidade da cliente e o trabalho de desenho de sua marca gráfica foram estabelecidos com a utilização de recursos de Branding, área que trata do desenvolvimento conceitual da marca. Para o processo de pesquisa e criação, utilizou-se como base a metodologia adaptada de Wheeler (2012) com o complemento da metodologia de Peón (2001). A solução final da marca gráfica foi selecionada junto à cliente e aperfeiçoada de acordo com seus conceitos e seu público-alvo.This is the report on the development and presentation of the results of the Design Course Completion Project (CCP) in the context of the Graphic Design Management area. The focus of the project was on the design of the visual signature of the professional Rosane Sommer, who identifies, represents and qualifies an autonomous therapist who provides services in the scope of alternative therapies. The research process on the identity of the client and the work of drawing their graphic brand were established using Branding resources, an area that deals with the conceptual development of the brand. For the research and creation process, the methodology adapted from Wheeler (2012) was used as a basis with the complement of the methodology of Peón (2001). The final solution of the graphic brand was selected with the client and improved according to their concepts and their target audience

    Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone

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    AbstractEmergence of epidemic clones and antibiotic resistance development compromises the management of Pseudomonas aeruginosa cystic fibrosis (CF) chronic respiratory infections. Whole genome sequencing (WGS) was used to decipher the phylogeny, interpatient dissemination, WGS mutator genotypes (mutome) and resistome of a widespread clone (CC274), in isolates from two highly-distant countries, Australia and Spain, covering an 18-year period. The coexistence of two divergent CC274 clonal lineages was revealed, but without evident geographical barrier; phylogenetic reconstructions and mutational resistome demonstrated the interpatient transmission of mutators. The extraordinary capacity of P. aeruginosa to develop resistance was evidenced by the emergence of mutations in &gt;100 genes related to antibiotic resistance during the evolution of CC274, catalyzed by mutator phenotypes. While the presence of classical mutational resistance mechanisms was confirmed and correlated with resistance phenotypes, results also showed a major role of unexpected mutations. Among them, PBP3 mutations, shaping up β-lactam resistance, were noteworthy. A high selective pressure for mexZ mutations was evidenced, but we showed for the first time that high-level aminoglycoside resistance in CF is likely driven by mutations in fusA1/fusA2, coding for elongation factor G. Altogether, our results provide valuable information for understanding the evolution of the mutational resistome of CF P. aeruginosa.</jats:p

    Sisyphus Cooling of Electrically Trapped Polyatomic Molecules

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    The rich internal structure and long-range dipole-dipole interactions establish polar molecules as unique instruments for quantum-controlled applications and fundamental investigations. Their potential fully unfolds at ultracold temperatures, where a plethora of effects is predicted in many-body physics, quantum information science, ultracold chemistry, and physics beyond the standard model. These objectives have inspired the development of a wide range of methods to produce cold molecular ensembles. However, cooling polyatomic molecules to ultracold temperatures has until now seemed intractable. Here we report on the experimental realization of opto-electrical cooling, a paradigm-changing cooling and accumulation method for polar molecules. Its key attribute is the removal of a large fraction of a molecule's kinetic energy in each step of the cooling cycle via a Sisyphus effect, allowing cooling with only few dissipative decay processes. We demonstrate its potential by reducing the temperature of about 10^6 trapped CH_3F molecules by a factor of 13.5, with the phase-space density increased by a factor of 29 or a factor of 70 discounting trap losses. In contrast to other cooling mechanisms, our scheme proceeds in a trap, cools in all three dimensions, and works for a large variety of polar molecules. With no fundamental temperature limit anticipated down to the photon-recoil temperature in the nanokelvin range, our method eliminates the primary hurdle in producing ultracold polyatomic molecules. The low temperatures, large molecule numbers and long trapping times up to 27 s will allow an interaction-dominated regime to be attained, enabling collision studies and investigation of evaporative cooling toward a BEC of polyatomic molecules

    Indo-Brazilian Late Palaeozoic wildfires: an overview on macroscopic charcoal

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    Carvão vegetal macroscópico é amplamente aceito como um indicador direto da ocorrência de paleo-incêndios vegetacionais, sendo relativamente bem estudado e distribuído de forma homogênea em depósitos do Paleozoico Superior da Euramérica e Cataísia. Por outro lado, apenas alguns registros deste tipo de material foram publicados para o Paleozoico Superior do Gondwana e, somente recentemente foi demonstrado que carvão vegetal macroscópico (e, portanto, incêndios) também é comum no continente meridional. Os mais importantes registros do Gondwana se constituem em fragmentos carbonizados de lenhos gimnospérmicos e estão associados, principalmente, a depósitos de carvão mineral. Registros de macro-charcoal (carvão vegetal macroscópico) foram descritos para níveis do Paleozoico Superior da Bacia Damodar (Índia) e da Bacia do Paraná (Brasil), demonstrando que paleo-incêndios vegetacionais ocorriam em sequências e intervalos estratigráficos variados no Gondwana durante esse período. Com base nos registros publicados até o momento e em novos exemplares provenientes do nível de carvão Seam-IV, Formação Raniganj, Bacia Damodar (Lopingiano da Índia), uma revisão acerca dos registros indo-brasileiros de carvão vegetal macroscópico em níveis do Paleozoico Superior são apresentados. O material inédito foi analisado sob Microscópio Eletrônico de Varredura para a definição de características anatômicas, sendo estabelecida uma afinidade gimnospérmica para os fragmentos. Os dados apresentados reforçam a importância dos paleo-incêndios vegetacionais como elemento perturbador dos diferentes paleoambientes gondvânicos durante o Paleozoico Superior.Sedimentary charcoal is widely accepted as a direct indicator for the occurrence of paleo-wildfires and, in Upper Paleozoic sediments of Euramerica and Cathaysia, reports on such remains are relatively common and (regionally and stratigraphically) more or less homogeneously distributed. On the contrary, just a few reliable records have been published for the Late Paleozoic of Gondwana and only recently it has been demonstrated that macroscopic charcoals (and thus fires) were also common in the southern continent during this period. The most important Gondwanan records are predominantly charred gymnosperm woods mainly related to coal bearing strata. Late Paleozoic macro-charcoal occurs in both, the Damodar Basin (India) and the Paraná Basin (Brazil), demonstrating that paleo-wildfires were spread out in different sequences and distinct stratigraphic intervals during this period in Gondwana. Based on the so far published records as well as new samples from the Seam-VI coalfield, Raniganj Formation (Damodar Basin – Lopingian of India), an overview of the Late Paleozoic Indo‑Brazilian macro-charcoal remains is presented. The hitherto unpublished samples were anatomically analyzed under Scanning Electron Microscope and a gymnosperm affinity could be established. The data presented here reinforce the relevance of paleo-wildfire as a source of environmental disturbance over large areas of Gondwana during the Late Paleozoic

    Tailoring of magnetocaloric effect in Ni45.5Mn43.0In11.5 metamagnetic shape memory alloy

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    We investigate the direct and inverse magnetocaloric effect in Ni45.5Mn43.0In11.5 Heusler alloy ribbons comparing the results obtained for the as-quenched sample with the ones after different annealing procedures. An enhancement and shift of the entropy maximum to near room temperature is observed in all annealed samples. A remarkable magnetocaloric effect is observed in samples with short-time treatment (10 minutes) and at the lowest annealing temperature. We show that the suppressing of uncompensated martensitic transition and thermal hysteresis are both influenced by the heat treatment. Also, an improvement on Curie’s temperature is observed and, at low magnetic field, it has been risen up to 310 K. Our results demonstrate that the martensitic transformation is highly sensitive to the applied magnetic field and also to the annealing treatment, which means that the magnetocaloric effect can be tuned showing different behaviors for each sample.Authors are thankful to Spanish MICINN for financial support: MAT2009-13108-C02-01-02 and MAT2010-20798-C05-04. L. Gonzalez also thanks MICINN for a FPI Grant and J. García FICYT for a “Severo Ochoa” Grant
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