219 research outputs found
Numerical solutions of nonlinear evolution equations using variational iteration method
AbstractThe variational iteration method is used to solve three kinds of nonlinear partial differential equations, coupled nonlinear reaction diffusion equations, Hirota–Satsuma coupled KdV system and Drinefel’d–Sokolov–Wilson equations. Numerical solutions obtained by the variational iteration method are compared with the exact solutions, revealing that the obtained solutions are of high accuracy. He's variational iteration method is introduced to overcome the difficulty arising in calculating Adomian polynomial in Adomian method. The method is straightforward and concise, and it can also be applied to other nonlinear evolution equations in mathematical physics
Congenital Hypothyroidism: Effects on Linear Growth, Catch- Up Growth, GH-IGF-I Axis and Bones
Clinico-radiographic Studies on The Prevalent Distal Limb Affections in Working Equine at Luxor City
To illustrate the clinical and radiographic findings of some distal limbs affections in Ninety two animals (24 horses and 68 donkeys) which were admitted to Animal Care Hospital in Luxor. Each animal was subjected to thorough clinical and radiographic examination; the grade of lameness was recorded and the best radiographic views were taken. Fifteen types of distal limb affections were evident. The most prevalent affections in donkeys were high and low ring bone (29.35%) and hoof abscess ( 9.78%) followed by traumatic arthritis of the fetlock (6.52%), suspensory ligament desmitis (5.43%), fracture of first phalanx (5.43%), fracture of PII (4.35%), side bone (3.26%) whereas, fracture of metacarpal bone (1.09%), sesamoditis (1.09%) and flexural deformities (1.09%) represented the lowest prevalent affections.On the other hand, side bone (4.35%), fracture of the metacarpal bone (4.35%) represented the most prevalent affections in horses followed by high and low ring bone (3.26%), fractures of PI (2.17%), PII (2.17%), subluxation of coronopedal joint (2.17%) and punctured wounds in of the hoof (2.17%), traumatic arthritis of the fetlock joint (2.17%). Whereas, navicular disease (1.09%), suspensory ligament desmitis (1.09%) and hoof abscess (1.09%) were the lowest prevalent affections in horses. Treatment was not recommended in certain cases. In conclusion, although the wide stride progress have made in diagnostic imaging in recent decades, the x ray still offers a satisfactory tool for diagnostic imaging in equine limb practice that is useful for equine practitioners
Effect of Modifying Mechanical Ventilator Trigger Sensitivity on Arterial Blood Gases in ICU Patients
Background: Despite the fact that mechanical ventilation is an essential part in management of critically ill patients, mechanically ventilated patients have a higher risk of complications, which can lead to increased morbidity and mortality.
Objective: This study aimed to study the effect of training inspiratory muscle through modifying mechanical ventilator (MV) trigger sensitivity on arterial blood gases in mechanically ventilated patients.
Patients and Methods: Sixty adult patients diagnosed with acute respiratory failure, needed to be intubated and connected to mechanical ventilated. They were from both gender and their ages ranged from 50 to 70 years. The patient were chosen from Intensive Care Unit (ICU), Department of Chest Diseases, Cairo University Hospitals. They were randomly assigned into two equal groups. Group (A): included thirty patients who received training for inspiratory muscle through modifying MV trigger sensitivity plus usual physical therapy. Group (B): included thirty patients who received usual physical therapy only.
Results: The results showed a significant increase in partial arterial pressure (PaO2) in both groups, this increasing was significantly higher in patients who received training for the inspiratory muscle plus the usual chest physical therapy than patients who only received usual chest physical therapy (P-value < 0.001). The results showed no significant change in neither power of hydrogen (pH) nor partial pressure of carbon dioxide (PaCO2).
Conclusion: Training to inspiratory muscles in mechanically ventilated patient through modifying mechanical ventilator trigger sensitivity can produce a significant increase in partial arterial pressure (PaO2). Although it has no effect in pH nor PaCO2
Influence of Reaction Time, Reducing Agent and Zinc Precursors on the Morphological Structures of Zinc Oxide
ZnO either nanoparticles or nanorods were synthesized via sol-gel technique. Many factors were studied and optimized in order to obtain different morphological structures of nano-ZnO. Effect of reaction time (3, 6, 12, 24 and 48 hours) has been studied to optimize the best preparation condition. Reducing agent (NH3, NaOH and KOH) is one of the factors affect on morphological structures, which has been studied in this work. Other effect has been studied in this work is zinc precursors such as Zn(NO3)2, ZnAc2, ZnCl2, and ZnBr2. The morphological structures of prepared ZnO were revealed using scanning electron microscope (SEM) and the aspect ratios were calculated. x-ray diffraction (XRD) patternsexposed a highly crystallized wurtzite structure and used for identifying phase structure and chemical state of ZnO under different preparation conditions.Keywords: sol-gel, morphological structures, reducing agent, SEM, preparation conditions
Synthesis, characterization and molecular modeling of new ruthenium(II) complexes with nitrogen and nitrogen/oxygen donor ligands
Ru(II) complexes with some dinitrogen ligands; 3,4-diamino benzoic acid (DABA), 2-hydazinopyridine (hzpy), 2,2′-bipyridyl (bipy) and anthranilic acid (anth) have been synthesized and characterized by using IR, mass, and UV–Vis spectrometry and thermal analysis. The thermodynamic parameters (ΔE, ΔH, ΔS and ΔG) have been calculated by using Coats–Redfern and Horowitz–Metzger methods. The electrochemical properties of these complexes have been studied by using cyclic voltammetry. The evaluated energies of the HOMO and LUMO are in the range of −4.94 to −4.85 eV and −2.86 to −2.68 eV, respectively. The complexes have been proven to have an octahedral geometry with DABA, hzpy and bipy as N2 donor ligands and NSC as monodentate ligand. The structure of the Ru(II) complexes has been geometrically optimized by using parameterized PM3 semiempirical method. © 2015 The Author
Curvas dadas por la intersección transversal de dos superficies en el espacio tridimesional de Minkowski
In this paper, we study the differential geometry of the transversal intersection curve of two surfaces in Minkowski 3-space, where each pair satisfies the following types spacelike-lightlike, timelike-lightlike and lightlike-lightlike. Surfaces are generally give by their parametric or implicit equations, then the surfacesurface intersection problem appear commonly as parametric-parametric, parametric-implicit and implicitimplicit.We derive the Frenet frame, Darboux frame, curvature, torsion, normal curvature and geodesic curvatures of transversal intersections for all types of intersection problems. We show the intersection curve may be spacelike (timelike, lightlike or pseudo null) curve. Finally, we show our methods by given several examples.En este artículo, estudiamos la geometría diferencial de la curva dada por la intersección transversal de dos superficies en el espacio tridimensional de Minkowski donde cada par satisface los siguientes tipos de superficies; tipo espacio - tipo luz, tipo tiempo - tipo luz y tipo luz - tipo luz. Generalmente, las superficies están dadas por sus ecuaciones paramétricas o implícitas, entonces el problema de intersección superficie superficie aparece comunmente como paramétrico-paramétrico, paramétrico-implícito e implícito-implícito. Obtenemos el Referencial de Frenet, el Referencial de Darboux, la curvatura, la torsión, la curvatura normal y las curvaturas geodésicas de las intersecciones transversales para todos los tipos de problemas de intersección. Mostramos que la curva de intersección puede ser una curva similar a una curva tipo espacio (tipo tiempo, tipo luz o pseudo nula). Finalmente, mostramos nuestros métodos por varios ejemplos
Histological and ultrastructural studies on the effect of Cassia alata methanolic leaf extracts against chemically induced lung adenocarcinoma in rats
ABSTRACT The present work aims to evaluate anticancer performance of Cassia alata methanolic leaf extracts (CMLE) in ethyl carbamate-stimulated lung adenocarcinoma (LAD) in differentiation to the function of Cisplatin (CIPL). Rats were divided into four groups: (1) control (CONT), (2) lung-adenocarcinoma (LAD) injected intra-peritoneally with 1g/kg ethyl carbamate once weekly for a month, (3) LAD+CMLE administered 500 mg/kg CMLE orally for the last two months of the experiment, and (4) LAD+CIPL treated group, injected 2.5 mg/kg Cisplatin intraperitoneally once weekly for the last two months of the experiment. Light and electron microscopic examinations revealed adenocarcinoma development in terminal bronchiole besides some histopathological changes in the LAD group such as atypical, exaggerated collagen fibers, increment of mucinous content, and increasing of PCNA positive immunoreactivity whereas electron microscopy investigation exposed that papillary adenocarcinoma originated from Clara cells in the LAD group. The LAD+CMLE treated group showed no tumor masses and nearly all with normal lung histology. It also recovered the normal ultrastructure of bronchiolar Clara cells. CMLE treatment offers a new alternative cure with less toxicity than Cisplatin for lung cancer therapy. Hence, CMLE would be employed as a novel supply of anti-cancer compounds combating lung cancer
Influence of Reaction Time, Reducing Agent and Zinc Precursors on the Morphological Structures of Zinc Oxide
ZnO either nanoparticles or nanorods were synthesized via sol-gel technique. Many factors were studied and optimized in order to obtain different morphological structures of nano-ZnO. Effect of reaction time (3, 6, 12, 24 and 48 hours) has been studied to optimize the best preparation condition. Reducing agent (NH3, NaOH and KOH) is one of the factors affect on morphological structures, which has been studied in this work. Other effect has been studied in this work is zinc precursors such as Zn (NO3)2, ZnAc2, ZnCl2, and ZnBr2. The morphological structures of prepared ZnO were revealed using scanning electron microscope (SEM) and the aspect ratios were calculated. x-ray diffraction (XRD) patterns exposed a highly crystallized wurtzite structure and used for identifying phase structure and chemical state of ZnO under different preparation conditions
Natural Polymers in Micro- and Nanoencapsulation for Therapeutic and Diagnostic Applications: Part I: Lipids and Fabrication Techniques
Encapsulation, specifically microencapsulation is an old technology with increasing applications in pharmaceutical, agrochemical, environmental, food, and cosmetic spaces. In the past two decades, the advancements in the field of nanotechnology opened the door for applying the encapsulation technology at the nanoscale level. Nanoencapsulation is highly utilized in designing effective drug delivery systems (DDSs) due to the fact that delivery of the encapsulated therapeutic/diagnostic agents to various sites in the human body depends on the size of the nanoparticles. Compared to microencapsulation, nanoencapsulation has superior performance which can improve bioavailability, increase drug solubility, delay or control drug release and enhance active/passive targeting of bioactive agents to the sites of action. Encapsulation, either micro- or nanoencapsulation is employed for the conventional pharmaceuticals, biopharmaceuticals, biologics, or bioactive drugs from natural sources as well as for diagnostics such as biomarkers. The outcome of any encapsulation process depends on the technique employed and the encapsulating material. This chapter discusses in details (1) various physical, mechanical, thermal, chemical, and physicochemical encapsulation techniques, (2) types and classifications of natural polymers (polysaccharides, proteins, and lipids) as safer, biocompatible and biodegradable encapsulating materials, and (3) the recent advances in using lipids for therapeutic and diagnostic applications. Polysaccharides and proteins are covered in the second part of this chapter
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