Transit Timing Observations from Kepler. VIII Catalog of Transit Timing Measurements of the First Twelve Quarters

Following Ford et al. (2011, 2012) and Steffen et al. (2012) we derived the transit timing of 1960 Kepler KOIs using the pre-search data conditioning (PDC) light curves of the first twelve quarters of the Kepler data. For 721 KOIs with large enough SNRs, we obtained also the duration and depth of each transit. The results are presented as a catalog for the community to use. We derived a few statistics of our results that could be used to indicate significant variations. Including systems found by previous works, we have found 130 KOIs that showed highly significant TTVs, and 13 that had short-period TTV modulations with small amplitudes. We consider two effects that could cause apparent periodic TTV - the finite sampling of the observations and the interference with the stellar activity, stellar spots in particular. We briefly discuss some statistical aspects of our detected TTVs. We show that the TTV period is correlated with the orbital period of the planet and with the TTV amplitude.Comment: Accepted for publication to ApJ. 57 pages, 23 Figures. Machine readable catalogs are available at ftp://wise-ftp.tau.ac.il/pub/tauttv/TT

Dominance of particulate organic carbon in top mineral soils in cold regions

18 páginas.- 4 figuras.- 63 referencias.- Supplementary information The online version contains supplementary material available at https://doi.org/10.1038/s41561-023-01354-5The largest stocks of soil organic carbon can be found in cold regions such as Arctic, subarctic and alpine biomes, which are warming faster than the global average. Discriminating between particulate and mineral-associated organic carbon can constrain the uncertainty of projected changes in global soil organic carbon stocks. Yet carbon fractions are not considered when assessing the contribution of cold regions to land carbon–climate feedbacks. Here we synthesize field paired observations of particulate and mineral-associated organic carbon in the mineral layer, along with experimental warming data, to investigate whether the particulate fraction dominates in cold regions and whether this relates to higher soil organic carbon losses with warming than in other (milder) biomes. We show that soil organic carbon in the first 30 cm of mineral soil is dominated or co-dominated by particulate carbon in both permafrost and non-permafrost soils, and in Arctic and alpine ecosystems but not in subarctic environments. Our findings indicate that soil organic carbon is most vulnerable to warming in cold regions compared with milder biomes, with this vulnerability mediated by higher warming-induced losses of particulate carbon. The massive soil carbon accumulation in cold regions appears distributed predominantly in the more vulnerable particulate fraction rather than in the more persistent mineral-associated fraction, supporting the likelihood of a strong, positive land carbon–climate feedback.We thank all authors who gathered and published the raw data in the original studies that enabled this literature synthesis. P.G.-P. acknowledges support from the Spanish Ministry of Science and Innovation via the I+D+i project PID2020-113021RA-I00 and the TED project TED2021-130908A-C42 (funded by European Union—NextGenerationEU). Work at Lawrence Livermore National Laboratory by N.W.S. was performed under the auspices of the US DOE OBER, under contract DE-AC52-07NA27344 award #SCW1632. M.P. acknowledges financial support by the Comunidad de Madrid and the Spanish National Council of Scientific Researches research grant Atracción de Talento (grant number 2019T1/AMB14503).Peer reviewe

Faecalibacterium prausnitzii : from microbiology to diagnostics and prognostics

We thank Dr Xavier Aldeguer and MD David Busquets from the Hospital Dr Josep Trueta (Girona, Spain) and M.D Míriam Sabat Mir from the Hospital Santa Caterina (Salt, Spain) for their help and critical discussion concerning clinical aspects. This work was partially funded by the Spanish Ministry of Education and Science through the projects SAF2010-15896 and SAF2013-43284-P, which has been co-financed with FEDER funds. Dr Sylvia H Duncan acknowledges support from the Scottish Government Food, Land and People program.Peer reviewedPostprin

Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility

peer reviewe

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries