3,582 research outputs found
Prediction of Wind Tunnel Effects on the Installed F/A-18A Inlet Flow Field at High Angles-of-attack
NASA Lewis is currently engaged in a research effort as a team member of the High Alpha Technology Program (HATP) within NASA. This program utilizes a specially equipped F/A-18A, the High Alpha Research Vehicle (HARV), in an ambitious effort to improve the maneuverability of high performance military aircraft at low subsonic speed, high angle of attack conditions. The overall objective of the Lewis effort is to develop inlet technology that will ensure efficient airflow delivery to the engine during these maneuvers. One part of the Lewis approach utilizes computational fluid dynamics codes to predict the installed performance of inlets for these highly maneuverable aircraft. Wind tunnel tests were a major component of the Lewis program. Since the available wind tunnel was small (9 x 15 ft) as compared to the scale of the model of the F/A-18A (19.78 percent), there were questions about the capability to obtain useful inlet performance data. The blockage effects were expected to be very large. This report represents the results of an analysis to determine how the wind tunnel walls effect inlet performance at several angles of attack. The predictions for the external particle traces along the fuselage indicate the influence of the wind tunnel side wall under the model is greater at 30 deg angle of attack than at 50 deg angle of attack on the under Leading Edge Extension (LEX) vortex trajectory. The side wall above the model appears to have negligible influence on the under LEX vortex. This may be due to the LEX acting as 'shield' to the upper wall effects. As expected, the wind tunnel has a significant influence on the external forces. The lift and drag coefficients increase significantly for the wind tunnel model as compared to free stream conditions. The wind tunnel had a small effect on the inlet recovery and on inlet total pressure distortion patterns. The predicted recoveries for the wind tunnel model are within one percentage point of the model recoveries in free stream conditions
A randomized trial of brief intervention strategies in patients with alcohol-related facial trauma as a result of interpersonal violence
Facial trauma is associated with male gender, low socioeconomic status, alcohol misuse, and violence. Brief intervention (BI) for alcohol is effective at reducing consumption in patients presenting with facial trauma. Singlesession control of violence for angry impulsive drinkers(SS-COVAID) is a new intervention that attempts to address alcohol-related violence. This study assessed the effect of SS-COVAID and BI on drinking and aggression in facial trauma patients. Male facial trauma patients who sustained their injuries as a result of interpersonal violence while drinking and who had Alcohol Use Disorders Identification Test (AUDIT) scores of ≥8 were randomized to either BI or SS-COVAID. Patients were followed up at six and 12 months, and drinking and aggression outcomes were analyzed. One hundred ninety-nine patients entered the trial, and 187 were included in the analysis. Of these, 165 (89%) considered themselves to be victims, 92 (51%) had sustained a previous alcohol-related injury, and 28
(15%) had previous convictions for violence. Both interventions resulted in a significant decrease in negative drinking outcomes over 12 months of follow-up (p<0.001). Neither intervention had a significant effect on aggression scores, nor was there a significant difference between interventions in terms of either outcome. Both SS-COVAID and BI had a significant effect on drinking variables in this patient cohort. No effect on aggressionwas seen despite the fact that SS-COVAID specifically addresses the relationship between alcohol and violence. One reason for this may be that the facial trauma patients in this study considered themselves to be victims rather than aggressors. Another possibility is that, while BI may successfully address lifestyle factors such as hazardous or harmful drinking, it may not be effective in modifying personality traits such as aggression
Thin-layer and full Navier-Stokes calculations for turbulent supersonic flow over a cone at an angle of attack
The proper use of a computational fluid dynamics code requires a good understanding of the particular code being applied. In this report the application of CFL3D, a thin-layer Navier-Stokes code, is compared with the results obtained from PARC3D, a full Navier-Stokes code. In order to gain an understanding of the use of this code, a simple problem was chosen in which several key features of the code could be exercised. The problem chosen is a cone in supersonic flow at an angle of attack. The issues of grid resolution, grid blocking, and multigridding with CFL3D are explored. The use of multigridding resulted in a significant reduction in the computational time required to solve the problem. Solutions obtained are compared with the results using the full Navier-Stokes equations solver PARC3D. The results obtained with the CFL3D code compared well with the PARC3D solutions
Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke
Aims:
Cerebral small vessel disease (SVD) causes a fifth of all strokes plus diffuse brain damage leading to cognitive decline, physical disabilities and dementia. The aetiology and pathogenesis of SVD are unknown, but largely attributed to hypertension or microatheroma.
Methods:
We used the spontaneously hypertensive stroke-prone rat (SHRSP), the closest spontaneous experimental model of human SVD, and age-matched control rats kept under identical, non-salt-loaded conditions, to perform a blinded analysis of mRNA microarray, qRT-PCRand pathway analysis in two brain regions (frontal and midcoronal) commonly affected by SVD in the SHRSP at age five, 16 and 21 weeks.
Results:
We found gene expression abnormalities, with fold changes ranging from 2.5 to 59 for the 10 most differentially expressed genes, related to endothelial tight junctions (reduced), nitric oxide bioavailability (reduced), myelination (impaired), glial and microglial activity (increased), matrix proteins (impaired), vascular reactivity (impaired) and albumin (reduced), consistent with protein expression defects in the same rats. All were present at age 5 weeks thus pre-dating blood pressure elevation. âNeurologicalâ and âinflammatoryâ pathways were more affected than âvascularâ functional pathways.
Conclusions:
This set of defects, although individually modest, when acting in combination could explain the SHRSP's susceptibility to microvascular and brain injury, compared with control rats. Similar combined, individually modest, but multiple neurovascular unit defects, could explain susceptibility to spontaneous human SVD
Discovery of a Young Radio Pulsar in a Relativistic Binary Orbit
We report on the discovery of PSR J1141-6545, a radio pulsar in an eccentric,
relativistic 5-hr binary orbit. The pulsar shows no evidence for being
recycled, having pulse period P = 394 ms, characteristic age tau_c = 1.4 x 10^6
yr, and inferred surface magnetic dipole field strength B = 1.3 x 10^12 G. From
the mass function and measured rate of periastron advance, we determine the
total mass in the system to be (2.300 +/- 0.012) solar masses, assuming that
the periastron advance is purely relativistic. Under the same assumption, we
constrain the pulsar's mass to be M_p < 1.348 solar masses and the companion's
mass to be M_c > 0.968 solar masses (both 99% confidence). Given the total
system mass and the distribution of measured neutron star masses, the companion
is probably a massive white dwarf which formed prior to the birth of the
pulsar. Optical observations can test this hypothesis.Comment: 18 pages, 4 figures, Accepted for Publication in Ap
XMMU J0541.8-6659, a new supernova remnant in the Large Magellanic Cloud
The high sensitivity of the XMM-Newton instrumentation offers the opportunity
to study faint and extended sources in the Milky Way and nearby galaxies such
as the Large Magellanic Cloud (LMC) in detail. The ROSAT PSPC survey of the LMC
has revealed more than 700 X-ray sources, among which there are 46 supernova
remnants (SNRs) and candidates. We have observed the field around one of the
most promising SNR candidates in the ROSAT PSPC catalogue, labelled [HP99] 456
with XMM-Newton, to determine its nature. We investigated the XMM-Newton data
along with new radio-continuum, near infrared and optical data. In particular,
spectral and morphological studies of the X-ray and radio data were performed.
The X-ray images obtained in different energy bands reveal two different
structures. Below 1.0 keV the X-ray emission shows the shell-like morphology of
an SNR with a diameter of ~73 pc, one of the largest known in the LMC. For its
thermal spectrum we estimate an electron temperature of (0.49 +/- 0.12)keV
assuming non-equilibrium ionisation. The X-ray images above 1.0 keV reveal a
less extended source within the SNR emission, located ~1' west of the centre of
the SNR and coincident with bright point sources detected in radio-continuum.
This hard component has an extent of 0.9' (i.e. ~13 pc at a distance of ~50
kpc) and a non-thermal spectrum. The hard source coincides in position with the
ROSAT source [HP99] 456 and shows an indication for substructure. We firmly
identify a new SNR in the LMC with a shell-like morphology and a thermal
spectrum. Assuming the SNR to be in the Sedov phase yields an age of ~23 kyr.
We explore possible associations of the hard non-thermal emitting component
with a pulsar wind nebula (PWN) or background active galactic nuclei (AGN).Comment: 8 pages, 7 figures, accepted for publication in Astronomy and
Astrophysic
The Parkes Multibeam Pulsar Survey: PSR J1811-1736 - a pulsar in a highly eccentric binary system
We are undertaking a high-frequency survey of the Galactic plane for radio
pulsars, using the 13-element multibeam receiver on the 64-m Parkes radio
telescope. We describe briefly the survey system and some of the initial
results. PSR J1811-1736, one of the first pulsars discovered with this system,
has a rotation period of 104 ms. Subsequent timing observations using the 76-m
radio telescope at Jodrell Bank show that it is in an 18.8-day,
highly-eccentric binary orbit. We have measured the rate of advance of
periastron which indicates a total system mass of 2.6 +- 0.9 Msun, and the
minimum companion mass is about 0.7 Msun. This, the high orbital eccentricity
and the recycled nature of the pulsar suggests that this system is composed of
two neutron stars, only the fourth or fifth such system known in the disk of
the Galaxy.Comment: 6 pages, 3 embedded EPS figures, to be published in MNRA
Women, anger, and aggression an interpretative phenomenological analysis
This study reports a qualitative phenomenological investigation of anger and anger-related aggression in the context of the lives of individual women. Semistructured interviews with five women are analyzed using interpretative phenomenological analysis. This inductive approach aims to capture the richness and complexity of the lived experience of emotional life. In particular, it draws attention to the context-dependent and relational dimension of angry feelings and aggressive behavior. Three analytic themes are presented here: the subjective experience of anger, which includes the perceptual confusion and bodily change felt by the women when angry, crying, and the presence of multiple emotions; the forms and contexts of aggression, paying particular attention to the range of aggressive strategies used; and anger as moral judgment, in particular perceptions of injustice and unfairness. The authors conclude by examining the analytic observations in light of phenomenological thinking
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