195 research outputs found

    In the mood: the dynamics of collective sentiments on Twitter

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    We study the relationship between the sentiment levels of Twitter users and the evolving network structure that the users created by @-mentioning each other. We use a large dataset of tweets to which we apply three sentiment scoring algorithms, including the open source Sentistrength program. Specifically we make three contributions. Firstly, we find that people who have potentially the largest communication reach (according to a dynamic centrality measure) use sentiment differently than the average user: for example, they use positive sentiment more often and negative sentiment less often. Secondly, we find that when we follow structurally stable Twitter communities over a period of months, their sentiment levels are also stable, and sudden changes in community sentiment from one day to the next can in most cases be traced to external events affecting the community. Thirdly, based on our findings, we create and calibrate a simple agent-based model that is capable of reproducing measures of emotive response comparable with those obtained from our empirical dataset

    A genetic algorithm approach for modelling low voltage network demands

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    Distribution network operators (DNOs) are increasingly concerned about the impact of low carbon technologies on the low voltage (LV) networks. More advanced metering infrastructures provide numerous opportunities for more accurate load flow analysis of the LV networks. However, such data may not be readily available for DNOs and in any case is likely to be expensive. Modelling tools are required which can provide realistic, yet accurate, load profiles as input for a network modelling tool, without needing access to large amounts of monitored customer data. In this paper we outline some simple methods for accurately modelling a large number of unmonitored residential customers at the LV level. We do this by a process we call buddying, which models unmonitored customers by assigning them load profiles from a limited sample of monitored customers who have smart meters. Hence the presented method requires access to only a relatively small amount of domestic customers' data. The method is efficiently optimised using a genetic algorithm to minimise a weighted cost function between matching the substation data and the individual mean daily demands. Hence we can show the effectiveness of substation monitoring in LV network modelling. Using real LV network modelling, we show that our methods perform significantly better than a comparative Monte Carlo approach, and provide a description of the peak demand behaviour

    Preparation For Fatherhood: A Role For Olfactory Communication During Human Pregnancy?

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    There is evidence across a range of bi-parental species that physiological changes may occur in partnered males prior to the birth of an infant. It has been hypothesised that these hormonal changes might facilitate care-giving behaviours, which could augment infant survival. The mechanism that induces these changes has not been identified, but evidence from several species suggests that odour may play a role. The current study investigated this in humans by recording testosterone and psychological measures related to infant interest and care in men (n=91) both before and after exposure to odours from either pregnant women or non-pregnant control women. We found no evidence for an effect of odour cues of pregnancy on psychological measures including self-reported sociosexual orientation and social dominance scores, ratings of infant or adult faces, or testosterone levels. However, we found that brief exposure to post-partum odours significantly increased the reward value of infant faces. Our study is the first to show that the odour of peri-partum women may lead to upregulation of men’s interest in infants

    Targeted metagenomics of active microbial populations with stable-isotope probing

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    The ability to explore microbial diversity and function has been enhanced by novel experimental and computational tools. The incorporation of stable isotopes into microbial biomass enables the recovery of labeled nucleic acids from active microorganisms, despite their initial abundance and culturability. Combining stable-isotope probing (SIP) with metagenomics provides access to genomes from microorganisms involved in metabolic processes of interest. Studies using metagenomic analysis on DNA obtained from DNA-SIP incubations can be ideal for the recovery of novel enzymes for biotechnology applications, including biodegradation, biotransformation, and biosynthesis. This chapter introduces metagenomic and DNA-SIP methodologies, highlights biotechnology-focused studies that combine these approaches, and provides perspectives on future uses of these methods as analysis tools for applied and environmental microbiology

    The conserved C-terminus of the PcrA/UvrD helicase interacts directly with RNA polymerase

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    Copyright: © 2013 Gwynn et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: This work was supported by a Wellcome Trust project grant to MD (Reference: 077368), an ERC starting grant to MD (Acronym: SM-DNA-REPAIR) and a BBSRC project grant to PM, NS and MD (Reference: BB/I003142/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD
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