La música: una herramienta lúdica para fortalecer el lenguaje en niños del grado jardín del colegio Franciscano del Virrey Solís

La presente investigación nació de las observaciones e intervenciones pedagógicas que se realizaron con niños y niñas de primera infancia, evidenciando que el lenguaje verbal de los estudiantes del colegio Franciscano del Virrey Solís de grado jardín es limitado; a partir de esta problemática se propuso como objetivo el diseño de estrategias lúdico-musicales que permitan el fortalecimiento del lenguaje.La metodología desarrollada en la propuesta investigativa fue la cualitativa, enfocada en los procesos de observación y creación encontrando la relación del lenguaje con la música, se generaron tres instrumentos divididos en tres fases, estos fueron: la prueba diagnóstica, la cual consistió en el diseño de una clase inicial como base para el reconocimiento de las dificultades del lenguaje verbal que presentan los estudiantes del grado jardín, por otro lado, el registro bibliográfico se construyó un formato para buscar la recolección de la información de metodologías musicales, y por último, la cartilla musical la cual contiene cuatro experiencias pedagógicas articuladas al fortalecimiento del lenguaje en los niños y niñas del grado jardín, estas actividades son una guía para el desarrollo de más ejercicios que se pueden generar a lo largo de la práctica pedagógica.The present investigation was born from the observations and pedagogical interventions that were carried out with boys and girls from early childhood, showing that the verbal language of the students from the Colegio Franciscano del Virrey Solís in kindergarten is limited; from this one on problem was proposed as an objective the design of ludic-musical strategies that allow the language strengthening. The methodology developed in the research proposal was qualitative, focused on the processes of observation and creation finding the relationship between language and music, generated three instruments divided into three phases, these were: the diagnostic test, which consisted in the design of an initial class as a base for the recognition of the difficulties of the verbal language presented by the kindergarten grade students, on the other hand, the record bibliographical format, a format was built to search for the collection of information from musical methodologies, and finally, the musical primer which contains four experiences pedagogical activities articulated to the strengthening of the language in the boys and girls of the kindergarten grade, these activities are a guide for the development of more exercises that can be generated throughout pedagogical practice

Aproximación a la prevención del uso de sustancias psicoactivas a partir de los Conocimientos, actitudes y prácticas de consumidores activos

Objective To determine the knowledge, attitudes, and practices related to the consumption of psychoactive substances, alcohol, and tobacco in young consumers in the municipality of San Gil to generate strategies for the prevention of consumption. Methodology The research carried out was a cross-sectional study in which collected data through a validated and commonly used survey, consisting of 43 questions and divided into three parts, the first of knowledge, the second of attitudes and the third of practices, which was applied to young people between 18-27 years of age. age of the different neighborhoods of San Gil. Results The survey was answered by 140 volunteers, with a majority participation of women, indicating that the greatest consumption occurs in substances such as alcohol and tobacco. Discussion There has been evidence of an early onset of both cigarette and alcohol consumption and by the influence of a family member, so it is believed that the main prevention strategies should be aimed at education in the family. Conclusions The consumption of psychoactive substances has become a big problem nowadays since their naturalization has made us lose sight of the complications that they can have at the level of physical and mental health, therefore, the educational-preventive approach is urgent to alleviate this difficult health situation.Objetivo Determinar los Conocimientos, actitudes y prácticas relacionados con el consumo de sustancias psicoactivas, alcohol y tabaco en jóvenes consumidores del municipio de San Gil para generar estrategias de prevención del consumo. Metodología La investigación realizada fue un estudio de corte transversal en el que se recolectaron datos a través de una encuesta validada y de uso corriente, constituida por 43 preguntas y divida en tres partes, la primera de conocimientos, la segunda de actitudes y la tercera de prácticas, que fue aplicada a jóvenes entres los 18-27 años de edad de los diferentes barrios de San Gil. Resultados La encuesta fue respondida por 140 voluntarios, con una participación mayoritaria de mujeres, indicando que el mayor consumo se da en sustancias como el alcohol y el tabaco. Discusión Se ha evidenciado un inicio de consumo temprano tanto de cigarrillo como de alcohol y por influencia de algún familiar, con lo que, se cree que las principales estrategias de prevención deberían ir encaminadas a la educación en la familia. Conclusiones El consumo de las Sustancias psicoactivas se ha convertido en un gran problema actualmente ya que su naturalización ha hecho que se pierda de vista las complicaciones que pueden tener a nivel de salud física y mental, por lo tanto, el enfoque educativo- preventivo se hace urgente para paliar esta difícil situación de salud

Estado nutricional de los adultos mayores institucionalizados en siete hogares gerontológicos de la ciudad de Bogotá en el año 2017

In the elderly the nutritional status in Colombia follows the pattern of Latin America, protein-calorie malnutrition. There are no studies that demonstrate the risk factors for malnutrition in an institutionalized elderly, it is important to identify them since this age group has been increasing in the last decades, being able to identify nutritional alterations in time and thus preventing associated pathologies. In the present study, the nutritional status of the institutionalized elderly adults of the city of Bogota in the year 2017 was determined, characterizing them, establishing the prevalence of malnutrition and determining the nutritional status in relation to gender and age. was studied a sample of 80 elderly institutionalized in geriatric and gerontological homes in the city of Bogota between the ages of 60 and 99 years was screened and perimetric evaluation of the nutritional status was performed using the mini nutritional assessment scale. It was identified that 48% of the sample presented a risk of malnutrition, with a prevalence of 24% and in which women are 1.42 times more likely to show alterations in their nutritional status. Modifying factors such as the type of food, its mobility or considering polypharmacy as a risk for an inadequate nutritional status, it can reduce the prevalence of malnutrition in institutionalized patients reducing the burden for their caregivers, meaning to lower maintenance cost and mainly improving health in this type of population.En los adultos mayores el estado nutricional en Colombia sigue el patrón de América Latina, la malnutrición proteico-calórica. No se cuenta con estudios que demuestren los factores de riesgo para malnutrición en un adulto mayor institucionalizado, es importante identificarlos ya que este grupo etario viene en aumento en las últimas décadas, pudiéndose identificar a tiempo alteraciones nutricionales y previniendo así patologías asociadas. En el presente estudio se determinó el estado nutricional de los adultos mayores institucionalizados de la ciudad de Bogotá en el año 2017, caracterizándolos, estableciendo la prevalencia de malnutrición y determinando el estado nutricional en relación con el género y edad. Se realizó un muestreo en 80 adultos mayores institucionalizados en hogares geriátricos y gerontológicos de la ciudad de Bogotá entre los 60 y 99 años, a los cuales se les realizó un cribaje y evaluación perimétrica del estado nutricional mediante la escala Mini Nutritional Assessment. Se identificó que el 48% de la muestra presentaban riesgo de malnutrición, con una prevalencia del 24% y en el que las mujeres tienen 1,42 veces más riesgo de manifestar alteraciones en su estado nutricional. Modificando factores como el tipo de alimentación, su movilidad o considerando la polifarmacia como riesgo para un estado nutricional inadecuado, se puede llegar a disminuir la prevalencia de malnutrición en pacientes institucionalizados disminuyendo la carga para sus cuidadores, significando un menor costo de mantenimiento y principalmente mejorando la salud en este tipo de población.PregradoMédico(a) Cirujan

Characterization of Salmonella enterica contamination in pork and poultry meat from São Paulo/Brazil: Serotypes, genotypes and antimicrobial resistance profiles

Salmonellosis is a zoonosis of major relevance to global public health. Here we present the assessment of Salmonella enterica contamination in pork and poultry meat sold at retail markets in São Paulo, Brazil. A total of 780 meat samples (386 poultry meat and 394 pork samples) were collected from 132 markets. From these, 57 samples (7.3%) were positive for S. enterica isolation, including 32 (8.3%) poultry meat and 25 (6.3%) pork samples. S. enterica isolates were further characterized for serotyping, antimicrobial resistance and genotyping by amplified fragment length polymorphism and pulsed field gel electrophoresis. Antimicrobial resistance analysis demonstrated two main profiles: pork isolates were more resistant to macrolides, β-lactams, tetracycline, phenicols, and fluoroquinolones, and poultry meat isolates presented higher resistance to fluoroquinolones, sulfonamides, tetracycline, and β-lactams. A total of 72.4% of poultry meat isolates were identified as S. Heidelberg, while most of pork isolates were S. Typhimurium (31.7%) and S. Give (16.7%). Genotyping resulted in most clusters consisting exclusively of pork or poultry meat, no cross-contamination was detected, and a tendency to differentiate isolates according to their serotypes and markets of origin. High resistance rates to critically important antimicrobials reinforce the importance of controlling Salmonella contamination in meat production chains

¿Existieron vicios del razonamiento práctico en cuanto a la precipitación e inconsideración en el caso de la sentencia 01294 de 2018 del Consejo de Estado, analizado desde la prudencia política y jurídica?

13 p.A continuación, se planteará el caso de la ex representante a la cámara y senadora electa por el partido conservador colombiano Aida Merlano Rebolledo, quien perdió la investidura de su cargo en el año 2018 como consecuencia de la violación de los topes máximos de financiación de su campaña electoral, y se realizará un análisis detallado de los vicios del razonamiento prudencial de precipitación e inconsideración que se manifestaron tanto en su actuar como en el procedimiento judicial que se le realizó respectivamente. De esta manera, (y con los conceptos de los vicios del razonamiento ya entendidos) se aplicará lo establecido por prudencia jurídica y política en el caso en concreto para poder plantear una conclusión interpretativa objetiva sobre el actuar ético- moral de dicha mujer, y el por qué se expone que no fue el correcto, lo cual se espera de un jurista en el cual, los ciudadanos depositan su confianza para la buena administración de su país.Introducción Prudencia jurídica Prudencia política Resumen sentencia Vicios del razonamiento Conclusión Referencia

Polymorphisms within autophagy-related genes influence the risk of developing colorectal cancer: a meta-analysis of four large cohorts

The role of genetic variation in autophagy-related genes in modulating autophagy and cancer is poorly understood. Here, we comprehensively investigated the association of autophagy-related variants with colorectal cancer (CRC) risk and provide new insights about the molecular mechanisms underlying the associations. After meta-analysis of the genome-wide association study (GWAS) data from four independent European cohorts (8006 CRC cases and 7070 controls), two loci, DAPK2 (p = 2.19 × 10−5) and ATG5 (p = 6.28 × 10−4) were associated with the risk of CRC. Mechanistically, the DAPK2rs11631973G allele was associated with IL1 β levels after the stimulation of peripheral blood mononuclear cells (PBMCs) with Staphylococcus aureus (p = 0.002), CD24 + CD38 + CD27 + IgM + B cell levels in blood (p = 0.0038) and serum levels of en-RAGE (p = 0.0068). ATG5rs546456T allele was associated with TNF α and IL1 β levels after the stimulation of PBMCs with LPS (p = 0.0088 and p = 0.0076, respectively), CD14+CD16− cell levels in blood (p = 0.0068) and serum levels of CCL19 and cortisol (p = 0.0052 and p = 0.0074, respectively). Interestingly, no association with autophagy flux was observed. These results suggested an effect of the DAPK2 and ATG5 loci in the pathogenesis of CRC, likely through the modulation of host immune responses.This work was partially supported by grants from the Instituto de Salud Carlos III (Madrid, Spain; PI12/02688 and PI17/02256). CORSA was funded by the Austrian Research Promotion Agency (FFG) BRIDGE grant (no. 829675, to Andrea Gsur), the “Herzfelder’sche Familienstiftung” (grant to Andrea Gsur). Czech Republic CCS was funded by GACR grants (18–09709S, 19–10543S and 20–03997S), ProgresQ28/1.LF and UNCE/MED/006 grants. This article is based upon work from COST Action CA17118, supported by COST (European Cooperation in Science and Technology). A.K. is a recipient of a Ramalingaswami Re-Retry Faculty Fellowship (Grant; BT/RLF/Re-entry/38/2017) from the Department of Biotechnology (DBT), Government of India (GOI). V.M. received funding from the Agency for Management of University and Research Grants (AGAUR) of the Catalan Government grant 2017SGR723, the Instituto de Salud Carlos III, co-funded by FEDER funds–a way to build Europe–grants PI14-00613, PI17-00092 and the Spanish Association Against Cancer (AECC) Scientific Foundation grant GCTRA18022MORE. K.H. was supported by European Union Horizon 2020 grant No. 856620. We thank the CERCA Programme, Generalitat de Catalunya for institutional support

Home-based exercise program in the indeterminate form of Chagas disease (PEDI-CHAGAS study): A study protocol for a randomized clinical trial

BackgroundChagas disease (CD) is a neglected endemic disease with worldwide impact due to migration. Approximately 50–70% of individuals in the chronic phase of CD present the indeterminate form, characterized by parasitological and/or serological evidence of Trypanosoma cruzi infection, but without clinical signs and symptoms. Subclinical abnormalities have been reported in indeterminate form of CD, including pro-inflammatory states and alterations in cardiac function, biomarkers and autonomic modulation. Moreover, individuals with CD are usually impacted on their personal and professional life, making social insertion difficult and impacting their mental health and quality of life (QoL). Physical exercise has been acknowledged as an important strategy to prevent and control numerous chronic-degenerative diseases, but unexplored in individuals with the indeterminate form of CD. The PEDI-CHAGAS study (which stands for “Home-Based Exercise Program in the Indeterminate Form of Chagas Disease” in Portuguese) aims to evaluate the effects of a home-based exercise program on physical and mental health outcomes in individuals with indeterminate form of CD.Methods and designThe PEDI-CHAGAS is a two-arm (exercise and control) phase 3 superiority randomized clinical trial including patients with indeterminate form of CD. The exclusion criteria are <18 years old, evidence of non-Chagasic cardiomyopathy, musculoskeletal or cognitive limitations that preclude the realization of exercise protocol, clinical contraindication for regular exercise, and regular physical exercise (≥1 × per week). Participants will be assessed at baseline, and after three and 6 months of follow-up. The primary outcome will be QoL. Secondary outcomes will include blood pressure, physical fitness components, nutritional status, fatigability, autonomic modulation, cardiac morphology and function, low back pain, depression and anxiety, stress, sleep quality, medication use and adherence, and biochemical, inflammatory and cardiac biomarkers. Participants in the intervention group will undergo a home-based exercise program whilst those in the control group will receive only general information regarding the benefits of physical activity. Both groups will receive the same general nutritional counseling consisting of general orientations about healthy diets.ConclusionThe findings from the present study may support public health intervention strategies to improve physical and mental health parameters to be implemented more effectively in this population.Clinical trial registration[https://ensaiosclinicos.gov.br/rg/RBR-10yxgcr9/], identifier [U1111-1263-0153]

408 Cases of Genital Ambiguity Followed by Single Multidisciplinary Team during 23 Years: Etiologic Diagnosis and Sex of Rearing

Objective. To evaluate diagnosis, age of referral, karyotype, and sex of rearing of cases with disorders of sex development (DSD) with ambiguous genitalia. Methods. Retrospective study during 23 years at outpatient clinic of a referral center. Results. There were 408 cases; 250 (61.3%) were 46,XY and 124 (30.4%) 46,XX and 34 (8.3%) had sex chromosomes abnormalities. 189 (46.3%) had 46,XY testicular DSD, 105 (25.7%) 46,XX ovarian DSD, 95 (23.3%) disorders of gonadal development (DGD), and 19 (4.7%) complex malformations. The main etiology of 46,XX ovarian DSD was salt-wasting 21-hydroxylase deficiency. In 46,XX and 46,XY groups, other malformations were observed. In the DGD group, 46,XY partial gonadal dysgenesis, mixed gonadal dysgenesis, and ovotesticular DSD were more frequent. Low birth weight was observed in 42 cases of idiopathic 46,XY testicular DSD. The average age at diagnosis was 31.7 months. The final sex of rearing was male in 238 cases and female in 170. Only 6.6% (27 cases) needed sex reassignment. Conclusions. In this large DSD sample with ambiguous genitalia, the 46,XY karyotype was the most frequent; in turn, congenital adrenal hyperplasia was the most frequent etiology. Malformations associated with DSD were common in all groups and low birth weight was associated with idiopathic 46,XY testicular DSD

The Research Journey as a Challenge Towards New Trends

The academic community of the department of Risaralda, in its permanent interest in evidencing the results of the research processes that are carried out from the Higher Education Institutions and as a product of the VI meeting of researchers of the department of Risaralda held in November 2021 presents its work: “The journey of research as a challenge towards new trends”, which reflects the result of the latest research and advances in different lines of knowledge in Agricultural Sciences, Health Sciences, Social Sciences and Technology and Information Sciences, which seek to solve and meet the demands of the different sectors. This work would not have been possible without the help of each of the teachers, researchers and authors who presented their articles that make up each of the chapters of the book, to them our gratitude for their commitment, dedication and commitment, since their sole purpose is to contribute from the academy and science to scientific and technological development in the search for the solution of problems and thus contribute to transform the reality of our society and communities. We also wish to extend our gratitude to the institutions of the Network that made this publication possible: UTP, UCP, UNAD, UNIREMINGTON; UNISARC, CIAF, Universidad Libre, Uniclaretiana, Fundación Universitaria Comfamiliar and UNIMINUTO, institutions that in one way or another allowed this work to become a reality, which we hope will be of interest to you.Preface............................................................................................................................7 Chapter 1. Technologies and Engineering Towards a humanization in Engineering using soft skills in training in Engineers.............................................................................................................11 Omar Iván Trejos Buriticá1, Luis Eduardo Muñoz Guerrero Innovative materials in construction: review from a bibliometric analysis....................................................................................................................27 Cristian Osorio Gómez, Daniel Aristizábal Torres, Alejandro Alzate Buitrago, Cristhian Camilo Amariles López Bibliometric review of disaster risk management: progress, trends, and challenges.........................................................................................................51 Alejandro Alzate Buitrago, Gloria Milena Molina Vinasco. Incidence of land coverage and geology, in the unstability of lands of the micro-basin of the Combia creek, Pereira, Risaralda....................................73 Alejandro Alzate Buitrago, Daniel Aristizábal Torres. Chapter 2. Arts, Humanities, and Social Sciences Training experience with teachers teaching mathematics using the inquiry methodology ...............................................................................................95 Vivian Libeth Uzuriaga López, Héctor Gerardo Sánchez Bedoya. Interpretation of the multiple representations of the fears associated to the boarding of limited visual patients in the elective I students’ written productions and low vision ...................................................................................113 Eliana Bermúdez Cardona, Ana María Agudelo Guevara, Caterine Villamarín Acosta. The relevance of local knowledge in social sciences............................................131 Alberto Antonio Berón Ospina, Isabel Cristina Castillo Quintero. Basic education students’ conceptions of conflict a view from the peace for the education....................................................................................................143 Astrid Milena Calderón Cárdenas,Carolina Aguirre Arias, Carolina Franco Ossa, Martha Cecilia Gutiérrez Giraldo, Orfa Buitrago. Comprehensive risk prevention in educational settings: an interdisciplinary and socio-educational approach ............................................................................163 Olga María Henao Trujillo, Claudia María López Ortiz. Chapter 3. Natural and Agricultural Sciences Physicochemical characterization of three substrates used in the deep bedding system in swine .......................................................................................175 Juan Manuel Sánchez Rubio, Andrés Felipe Arias Roldan, Jesús Arturo Rincón Sanz, Jaime Andrés Betancourt Vásquez. Periodic solutions in AFM models........................................................................187 Daniel Cortés Zapata, Alexander Gutiérrez Gutiérrez. Phenology in flower and fruit of Rubus glaucus benth. Cv. Thornless in Risaralda: elements for phytosanitary management .........................................199 Shirley Palacios Castro, Andrés Alfonso Patiño Martínez, James Montoya Lerma, Ricardo Flórez, Harry Josué Pérez. Socio-economic and technical characterization of the cultivation of avocado (Persea americana) in Risaralda..............................................................217 Andrés Alfonso Patiño Martínez, Kelly Saudith Castañez Poveda, Eliana Gómez Correa. Biosecurity management in backyard systems in Santa Rosa de Cabal, Risaralda................................................................................................................227 Julia Victoria Arredondo Botero, Jaiver Estiben Ocampo Jaramillo, Juan Sebastián Mera Vallejo, Álvaro de Jesús Aranzazu Hernández. CONTENTS Physical-chemical diagnosis of soils in hillside areas with predominance of Lulo CV. La Selva production system in the department of Risaralda.............241 Adriana Patricia Restrepo Gallón, María Paula Landinez Montes, Jimena Tobón López. Digestibility of three concentrates used in canine feeding....................................271 María Fernanda Mejía Silva, Valentina Noreña Sánchez, Gastón Adolfo Castaño Jiménez. Chapter 4. Economic, Administrative, and Accounting Sciences Financial inclusion in households from socioeconomic strata 1 and 2 in the city of Pereira ..................................................................................................285 Lindy Neth Perea Mosquera, Marlen Isabel Redondo Ramírez, Angélica Viviana Morales. Internal marketing strategies as a competitive advantage for the company Mobilautos SAS de Dosquebradas........................................................................303 Inés Montoya Sánchez, Sandra Patricia Viana Bolaños, Ana María Barrera Rodríguez. Uses of tourist marketing in the tourist sector of the municipality of Belén de Umbría, Risaralda.............................................................................................319 Ana María Barrera Rodríguez, Paola Andrea Echeverri Gutiérrez, María Camila Parra Buitrago, Paola Andrea Martín Muñoz, Angy Paola Ángel Vélez, Luisa Natalia Trejos Ospina. Territorial prospective of Risaralda department (Colombia), based on the SDGS...............................................................................................................333 Juan Guillermo Gil García, Samanta Londoño Velásquez. Chapter 5. Health and Sports Sciences Performance evaluation in times of pandemic. What do medical students think?.......................................................................................................353 Samuel Eduardo Trujillo Henao, Rodolfo A. Cabrales Vega, Germán Alberto Moreno Gómez. The relevance of the therapist’s self and self-reference in the training of psychologists.....................................................................................................371 Maria Paula Marmolejo Lozano, Mireya Ospina Botero. Habits related to oral health which influence lifestyle of elder people in a wellness center for the elderly in Pereira 2020. .............................................387 Isadora Blanco Pérez, Olga Patricia Ramírez Rodríguez, Ángela María Rincón Hurtado. Analysis of the suicide trend in the Coffee Region in Colombia during the years 2012-2018 ..............................................................................................405 Germán Alberto Moreno Gómez, Jennifer Nessim Salazar, Jairo Franco Londoño, Juan Carlos Medina Osorio. Hind limb long bone fractures in canines and felines...........................................419 María Camila Cruz Vélez, Valentina Herrera Morales, Alba Nydia Restrepo Jiménez, Lina Marcela Palomino, Gabriel Rodolfo Izquierdo Bravo. Prevalence of overweight and obesity in children in the rural and urban area of Risaralda....................................................................................................439 Angela María Álvarez López, Angela Liceth Pérez Rendón, Alejandro Gómez Rodas, Luis Enrique Isaza Velásquez. Chapter 6. Architecture, Design and Advertising The artisan crafts of Risaralda, characteristics, importance, and risks within the Colombian Coffee Cultural Landscape, CCCL....................................457 Yaffa Nahir Ivette Gómez Barrera, Javier Alfonso López Morales