Volatilidade eleitoral nos 28 Estados-membros da União Europeia desde 1945 a 2012

Esta dissertação centra-se na volatilidade eleitoral nas democracias europeias entre 1945 a 2012. A volatilidade é um fenómeno cada vez mais estudado na europa e noutras regiões do mundo, dada a sua importância em termos de consequências para os sistemas políticos. Ambiciona-se saber quais os níveis de volatilidade eleitoral na União Europeia e, do ponto de vista agregado, o que explica a volatilidade eleitoral nas 28 democracias europeias entre 1945 até 2012? De modo a responder a esta questão de pesquisa analisámos 343 eleições de 28 estados-membros e considerámos a maioria dos preditores apontados na literatura como explicativos para a volatilidade eleitoral: características do sistema partidário, atributos do sistema eleitoral, características do sistema político em geral e indicadores socioeconómicos. Através de análises descritivas bivariadas foi possível determinar que existem diferenças assinaláveis entre as regiões europeias, e que a Europa central e oriental regista os maiores níveis de volatilidade. As análises multivariadas, em particular através de regressões lineares múltiplas, com os erros estandardizados robustos agrupados pelo país, permitiram determinar quais as dimensões que explicam estas diferenças: a dimensão política (longevidade da democracia) e a dimensão socioeconómica (índice de desenvolvimento humano, índice de gini e taxa do crescimento real do PIB).This thesis focuses on electoral volatility in European democracies from 1945 to 2012. Volatility is an increasingly studied phenomenon in Europe and also other world regions, given its importance regarding its consequences for the political systems. We aim to assess what are the levels of electoral volatility in the European Union and in the aggregate perspective, what explains the electoral volatility in 28 European democracies between 1945 and 2012. In order to answer to this research question, we examined 343 elections in the 28 member states and considered the majority of predictors identified, in previous literature, as possible explanations for electoral volatility: characteristics of the party system, electoral system attributes, characteristics of the political system in general and socio-economic indicators. Using descriptive bivariate analysis, we determined that there are significant differences between European regions and that Central and Eastern Europe have the highest levels of volatility. Multivariate analysis, in particular, multiple linear regressions with standardized robust errors clustered by country, determined which dimensions explained these differences: the political dimension (longevity of democracy) and the socio-economic dimension (human development index, GINI index and real GDP growth rate)

As Artes no Ensino Superior – ‘Pedagogias do evento’ no Doutoramento em Educação Artística

Este artigo pretende apresentar e refletir sobre várias experiências artísticas vivenciadas no contexto de um curso de doutoramento em Educação Artística, na Universidade de Lisboa. O curso existe desde 2011 na Universidade do Porto, mas, desde o ano letivo de 2016/17, a que este artigo se reporta, abriu também na Universidade de Lisboa, passando a conferir uma dupla certificação entre ambas as instituições. Na Universidade de Lisboa é organizado pelo Instituto de Educação e pela Faculdade de Belas Artes (Despacho nº 13244/2015, de 5 de novembro de 2015). Apesar de contactos constantes com a instituição do Porto, assumiu-se em Lisboa o caráter altamente aberto e experimental de todo o projeto curricular, entendendo-o como uma oportunidade de inovação e investigação no campo da pedagogia do ensino superior.info:eu-repo/semantics/publishedVersio

Vinte anos dos Estudos Eleitorais Portugueses, 2002-2022: A Base de Dados integrada

Para uma descrição completa do estudo, http://www.apis.ics.ulisboa.pt/catalogo/APIS0097.“Vinte anos dos Estudos Eleitorais Portugueses, 2002-2022” é uma base de dados integrada que junta os inquéritos pós-eleitorais conduzidos nos anos 2002, 2005, 2009, 2011, 2015, 2019 e 2022. Estes inquéritos junto da população adulta portuguesa têm o objetivo de medir o comportamento eleitoral (participação e opção de voto) em eleições legislativas, assim como uma série de potenciais correlatos, incluindo exposição aos media, discussão política e uma série de atitudes e valores políticos.info:eu-repo/semantics/updatedVersio

Reuma.pt/vasculitis - the Portuguese vasculitis registry

BACKGROUND: The vasculitides are a group of rare diseases with different manifestations and outcomes. New therapeutic options have led to the need for long-term registries. The Rheumatic Diseases Portuguese Register, Reuma.pt, is a web-based electronic clinical record, created in 2008, which currently includes specific modules for 12 diseases and > 20,000 patients registered from 79 rheumatology centres. On October 2014, a dedicated module for vasculitis was created as part of the European Vasculitis Society collaborative network, enabling prospective collection and central storage of encrypted data from patients with this condition. All Portuguese rheumatology centres were invited to participate. Data regarding demographics, diagnosis, classification criteria, assessment tools, and treatment were collected. We aim to describe the structure of Reuma.pt/vasculitis and characterize the patients registered since its development. RESULTS: A total of 687 patients, with 1945 visits, from 13 centres were registered; mean age was 53.4 ± 19.3 years at last visit and 68.7% were females. The most common diagnoses were Behçet's disease (BD) (42.5%) and giant cell arteritis (GCA) (17.8%). Patients with BD met the International Study Group criteria and the International Criteria for BD in 85.3 and 97.2% of cases, respectively. Within the most common small- and medium-vessel vasculitides registered, median [interquartile range] Birmingham Vasculitis Activity Score (BVAS) at first visit was highest in patients with ANCA-associated vasculitis (AAV) (17.0 [12.0]); there were no differences in the proportion of patients with AAV or polyarteritis nodosa who relapsed (BVAS≥1) or had a major relapse (≥1 major BVAS item) during prospective assessment (p = 1.00, p = 0.479). Biologic treatment was prescribed in 0.8% of patients with GCA, 26.7% of patients with AAV, and 7.6% of patients with BD. There were 34 (4.9%) deaths reported. CONCLUSIONS: Reuma.pt/vasculitis is a bespoke web-based registry adapted for routine care of patients with this form of rare and complex diseases, allowing an efficient data-repository at a national level with the potential to link with other international databases. It facilitates research, trials recruitment, service planning and benchmarking.publishersversionpublishe

description of the methodological approach

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Síndromes anêmicas: uma abordagem fisiopatológica sobre as principais considerações clínicas / Anemic syndromes: a pathophysiological approach to key clinical considerations

O seguinte artigo é uma revisão narrativa de literatura fundamentada nas plataformas do SciELO, LILACS, Pubmed, Google Acadêmico e Brazilian Journal of Health Review no período de janeiro a março de 2022. Atualmente, a anemia é algo que não é investigado sobre a sua etiologia e  sujeita a negligência, muitos pacientes são vítimas dos riscos de hemotransfusão e até privados de tratarem doenças que seriam possivelmente de manejo mais simples se detectadas precocemente. O seguinte artigo objetivou descrever as principais considerações sobre as síndrome anêmicas, em especial em sua  fisiopatologia e implicações clínicas. A temática de síndromes anêmicas é um tema complexo, que possui várias etiologias, apresentações clínicas, sintomatologias e meios diagnósticos. A terapêutica é focada em investigar o fator etiológico de base e simultaneamente tratar as implicações e aliviar o quadro clínico. Logo, o estudo em questão narra de modo detalhado a fisiopatologia da anemia e aborda as principais síndromes anêmicas para a clínica médica.

COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study

Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to Coronavirus disease 2019 (COVID-19) due to age, disease, and treatment-related immunosuppression. We aimed to assess risk factors of outcome and elucidate the impact of CLL-directed treatments on the course of COVID-19. We conducted a retrospective, international study, collectively including 941 patients with CLL and confirmed COVID-19. Data from the beginning of the pandemic until March 16, 2021, were collected from 91 centers. The risk factors of case fatality rate (CFR), disease severity, and overall survival (OS) were investigated. OS analysis was restricted to patients with severe COVID-19 (definition: hospitalization with need of oxygen or admission into an intensive care unit). CFR in patients with severe COVID-19 was 38.4%. OS was inferior for patients in all treatment categories compared to untreated (p < 0.001). Untreated patients had a lower risk of death (HR = 0.54, 95% CI:0.41–0.72). The risk of death was higher for older patients and those suffering from cardiac failure (HR = 1.03, 95% CI:1.02–1.04; HR = 1.79, 95% CI:1.04–3.07, respectively). Age, CLL-directed treatment, and cardiac failure were significant risk factors of OS. Untreated patients had a better chance of survival than those on treatment or recently treated

The evolving landscape of COVID‐19 and post‐COVID condition in patients with chronic lymphocytic leukemia: A study by ERIC, the European research initiative on CLL

In this retrospective international multicenter study, we describe the clinical characteristics and outcomes of patients with chronic lymphocytic leukemia (CLL) and related disorders (small lymphocytic lymphoma and high-count monoclonal B lymphocytosis) infected by SARS-CoV-2, including the development of post-COVID condition. Data from 1540 patients with CLL infected by SARS-CoV-2 from January 2020 to May 2022 were included in the analysis and assigned to four phases based on cases disposition and SARS-CoV-2 variants emergence. Post-COVID condition was defined according to the WHO criteria. Patients infected during the most recent phases of the pandemic, though carrying a higher comorbidity burden, were less often hospitalized, rarely needed intensive care unit admission, or died compared to patients infected during the initial phases. The 4-month overall survival (OS) improved through the phases, from 68% to 83%, p = .0015. Age, comorbidity, CLL-directed treatment, but not vaccination status, emerged as risk factors for mortality. Among survivors, 6.65% patients had a reinfection, usually milder than the initial one, and 16.5% developed post-COVID condition. The latter was characterized by fatigue, dyspnea, lasting cough, and impaired concentration. Infection severity was the only risk factor for developing post-COVID. The median time to resolution of the post-COVID condition was 4.7 months. OS in patients with CLL improved during the different phases of the pandemic, likely due to the improvement of prophylactic and therapeutic measures against SARS-CoV-2 as well as the emergence of milder variants. However, mortality remained relevant and a significant number of patients developed post-COVID conditions, warranting further investigations

Physics case for an LHCb Upgrade II - Opportunities in flavour physics, and beyond, in the HL-LHC era

The LHCb Upgrade II will fully exploit the flavour-physics opportunities of the HL-LHC, and study additional physics topics that take advantage of the forward acceptance of the LHCb spectrometer. The LHCb Upgrade I will begin operation in 2020. Consolidation will occur, and modest enhancements of the Upgrade I detector will be installed, in Long Shutdown 3 of the LHC (2025) and these are discussed here. The main Upgrade II detector will be installed in long shutdown 4 of the LHC (2030) and will build on the strengths of the current LHCb experiment and the Upgrade I. It will operate at a luminosity up to 2×1034 cm−2s−1, ten times that of the Upgrade I detector. New detector components will improve the intrinsic performance of the experiment in certain key areas. An Expression Of Interest proposing Upgrade II was submitted in February 2017. The physics case for the Upgrade II is presented here in more depth. CP-violating phases will be measured with precisions unattainable at any other envisaged facility. The experiment will probe b → sl+l−and b → dl+l− transitions in both muon and electron decays in modes not accessible at Upgrade I. Minimal flavour violation will be tested with a precision measurement of the ratio of B(B0 → μ+μ−)/B(Bs → μ+μ−). Probing charm CP violation at the 10−5 level may result in its long sought discovery. Major advances in hadron spectroscopy will be possible, which will be powerful probes of low energy QCD. Upgrade II potentially will have the highest sensitivity of all the LHC experiments on the Higgs to charm-quark couplings. Generically, the new physics mass scale probed, for fixed couplings, will almost double compared with the pre-HL-LHC era; this extended reach for flavour physics is similar to that which would be achieved by the HE-LHC proposal for the energy frontier

LHCb upgrade software and computing : technical design report

This document reports the Research and Development activities that are carried out in the software and computing domains in view of the upgrade of the LHCb experiment. The implementation of a full software trigger implies major changes in the core software framework, in the event data model, and in the reconstruction algorithms. The increase of the data volumes for both real and simulated datasets requires a corresponding scaling of the distributed computing infrastructure. An implementation plan in both domains is presented, together with a risk assessment analysis