Invisibilidade da mulher em situação de rua nos serviços especializados de atendimento à mulher

O presente artigo propõe uma reflexão sobre a necessidade de trazer o olhar das políticas públicas para um dos setores da sociedade em situação de maior vulnerabilidade: as mulheres em situação de rua. Além dos mais variados tipos de violência em função da sua condição, essas mulheres também estão sujeitas a sofrer violência doméstica. Na pesquisa, pretende-se examinar como se dá o acesso dessa mulher em situação de rua na rede de atendimento das vítimas de violência doméstica e familiar. Para tentar responder a essa questão, o estudo parte de levantamento bibliográfico e de pesquisa qualitativa. Em um primeiro momento, apresenta os diversos conceitos de gênero construídos por autoras feministas e algumas correntes teóricas para compreensão do fenômeno da violência contra as mulheres além de abordar a dinâmica da estadia da mulher no espaço da rua, formando assim o suporte teórico da pesquisa qualitativa realizada com duas juízas do Juizado de Violência Doméstica e Familar Contra Mulher, a delegada adjunta da Delegacia Especial de Atendimendo a Mulher e um psicólogo do Centro Especializado de Atendimento a Mulher, para apresentar situação da rede de atendimento à mulher vítima de violência doméstica do Distrito Federal quando a ofendida é mulher em situação de rua

Impacto da infecção pelo Papilomavírus Humano (HPV) no desenvolvimento de lesões orais

Oral squamous papilloma is a benign tumor, whose pathogenesis has been associated with human papillomavirus infection, which can affect any region of the oral cavity, being transmitted through direct contact, sexual intercourse or from mother to child during childbirth. Therefore, this article aimed to investigate the impact of HPV on the development of oral lesions and evaluate the relationship with pre-cancerous lesions, contributing to preventive understanding and early diagnosis of these conditions. To this end, an integrative literature review was carried out with studies retrieved from online databases: PubMed, and Virtual Health Library (LILACS and MEDLINE). The following inclusion criteria were adopted: original complete articles in English, Portuguese and Spanish, available in full, that addressed the topic and with a time frame of the last five years. 241 findings were located, including 10 studies according to the inclusion criteria established for this study. There are more than 100 types of HPV identified, and they are classified into high- and low-risk groups based on their oncogenic properties. Generally, lesions can occur in different regions of the oral cavity, such as the tongue, lips, buccal mucosa, gums and soft palate, manifesting as warts or papillomas. These lesions can be single or multiple, varying in size, color and shape, with an exophytic appearance. The absence of pain is common, however, some patients may report discomfort or irritation. The importance of early detection and appropriate intervention is highlighted to avoid complications and contribute to oral and general health. It is important to pay attention to existing knowledge and emphasize the need for preventive efforts, which are important to combat the spread of HPV and its implications.O papiloma escamoso oral é um tumor benigno, cuja patogênese tem sido associada à infecção pelo papilomavírus humano que pode acometer qualquer região da cavidade oral, sendo transmitido através de contato direto, relações sexuais ou de mãe para filho durante o parto. Deste modo, o presente artigo pretendeu investigar o impacto do HPV no desenvolvimento de lesões orais e avaliar a relação com lesões pré-cancerígenas, contribuindo para a compreensão preventiva e diagnóstico precoce dessas condições. Para tanto, foi realizada uma revisão integrativa da literatura com estudos recuperados nas bases de dados online: PubMed, e Biblioteca Virtual de Saúde (LILACS e MEDLINE). Adotaram-se como critérios de inclusão: artigos completos originais nos idiomas inglês, português e espanhol, disponíveis na íntegra, que abordassem a temática e com recorte temporal dos últimos cinco anos. Foram localizados 241 achados, onde se incluiu 10 estudos conforme os critérios de inclusão estabelecidos para esse estudo. Existem mais de 100 tipos de HPV identificados, e eles são classificados em grupo de alto e baixo risco com base em suas propriedades oncogênicas. Geralmente, as lesões podem ocorrer em diferentes regiões da cavidade bucal, como língua, lábios, mucosa jugal, gengivas e palato mole, manifestam-se como verrugas ou papilomas. Essas lesões podem ser únicas ou múltiplas, variando em tamanho, cor e forma, com aspecto exofítico. A ausência de dor é comum, porém, alguns pacientes podem relatar desconforto ou irritação. Ressalta-se a relevância da detecção precoce e da intervenção adequada para evitar complicações e contribuir para a saúde bucal e geral. É importante atentar aos conhecimentos existentes e enfatizar a necessidade de esforços preventivos, importantes para o combate à propagação do HPV e suas implicações

Em torno da mesa do rei: artefatos, convivialidade e celebração no Rio de Janeiro joanino

Este artigo aborda um aspecto relevante do ritual das refeições na corte de D. João VI, no Rio de Janeiro: a prataria de mesa. Isto é, objetos de luxo destinados a servir e a consumir os alimentos. Com base em um inventário de bens de mesa enviados do Rio de Janeiro para Lisboa junto com o monarca em seu retorno a Portugal, em 1821, este artigo procura refletir sobre as funções e possíveis usos desses objetos, assim como sobre a importância desse universo material para o funcionamento, representação e celebração da Casa Real portuguesa na sua nova sede. O artigo argumenta que a presença e o uso de baixelas de prata de serviço, mas também de grande aparato, nas refeições públicas da família real pode contribuir para se repensar a imagem de uma corte pobre e sem brilho recorrentemente reforçada na historiografia do período joanino.This article discusses a specific issue of the royal dinner's rituals at the Court of Rio de Janeiro: the silver service: some luxury artifacts of different forms specially made to serve and consume food. Based on a inventory of these silver objects and also on a stock of table linen which were shipped to Lisbon, along with the royal family in 1821, The article intend to explore the functions and utilities of those objects at the table, as well as, analyze the importance of this material universe for the functioning, representation and celebration of the Portuguese Royal House in its new headquarters.The article argues that the use and even the exhibition of the banquet silver in public ceremonies may contribute to change a rather depreciative image of poverty the royal court in Brazil, which has being explored by the historiography for more than a hundred years

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Expression profile of neurotransmitter receptor and regulatory genes in the prefrontal cortex of spontaneously hypertensive rats: Relevance to neuropsychiatric disorders

The spontaneously hypertensive rat (SHR) strain was shown to be a useful animal model to study several behavioral, pathophysiological and pharmacological aspects of schizophrenia and attention-deficit/hyperactivity disorder. To further understand the genetic underpinnings of this model, our primary goal in this study was to compare the gene expression profile of neurotransmitter receptors and regulators in the prefrontal cortex (PFC) and nucleus accumbens (NAcc) of SHR and Wistar rats (control group). in addition, we investigated DNA methylation pattern of promoter region of the genes differentially expressed. We performed gene expression analysis using a PCRarray technology, which simultaneously measures the expression of 84 genes related to neurotransmission. Four genes were significantly downregulated in the PFC of SHR compared to Wistar rats (Gad2, Chrnb4, Slc5a7, and Qrfpr) and none in nucleus accumbens. Gad2 and Qrfpr have CpG islands in their promoter region. for both, the promoter region was hypomethylated in SHR group, and probably this mechanism is not related with the downregulation of these genes. in summary, we identified genes that are downregulated in the PFC of SHR, and might be related to the behavioral abnormalities exhibited by this strain. (C) 2014 Elsevier Ireland Ltd. All rights reserved.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Fed Univ São Paulo UNIFESP, Div Genet, Dept Morphol & Genet, São Paulo, BrazilInterdisciplinmy Lab Clin Neurosci LiNC, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Psychiat, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Pharmacol, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Biophys, São Paulo, BrazilFed Univ São Paulo UNIFESP, Invest Ctr Gene Therapy, São Paulo, BrazilFed Univ São Paulo UNIFESP, Div Genet, Dept Morphol & Genet, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Psychiat, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Pharmacol, São Paulo, BrazilFed Univ São Paulo UNIFESP, Dept Biophys, São Paulo, BrazilFed Univ São Paulo UNIFESP, Invest Ctr Gene Therapy, São Paulo, BrazilWeb of Scienc

SNP typing reveals similarity in Mycobacterium tuberculosis genetic diversity between Portugal and Northeast Brazil

a Instituto Gulbenkian de Ciencia, 2781-901 Oeiras, Portugal b Instituto Nacional de Saude Dr. Ricardo Jorge, 4150-180 Porto, Portugal c Centro Hospitalar de Vila Nova de Gaia/Espinho, 4434-502 Vila Nova de Gaia, Portugal d Departamento de Epidemiologia Clinica, Medicina Preventiva e Saúde Pública, Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, Portugal e Direccao-Geral da Saude, 1049-005 Lisboa, Portugal f Instituto de Doenças do Torax, Universidade Federal do Rio de Janeiro, 21.941-913 Rio de Janeiro, Brazil g Instituto de Ciencias da Saude, Universidade Federal da Bahia, 40.150-510 Salvador, Brazil h Centro de Pesquisas Goncalo Moniz, Fundacao Oswaldo Cruz, 40.296-710 Salvador, Brazil i Centro de Pesquisa em Tuberculose, Universidade Federal do Rio de Janeiro, 21.941-913 Rio de Janeiro, BrazilSubmitted by Ana Maria Fiscina Sampaio ([email protected]) on 2017-08-29T17:26:32Z No. of bitstreams: 1 Lopes JS SNP typing reveals....pdf: 981211 bytes, checksum: 474bdf65e7c98d4a1ae19c4168888426 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2017-08-29T17:39:24Z (GMT) No. of bitstreams: 1 Lopes JS SNP typing reveals....pdf: 981211 bytes, checksum: 474bdf65e7c98d4a1ae19c4168888426 (MD5)Made available in DSpace on 2017-08-29T17:39:24Z (GMT). No. of bitstreams: 1 Lopes JS SNP typing reveals....pdf: 981211 bytes, checksum: 474bdf65e7c98d4a1ae19c4168888426 (MD5) Previous issue date: 2013National Counsel of Technological and Scientific Development (CNPQ) [Project Number 410498/2006-8] and Coordination of Improvement of Higher Education Personnel (CAPES) [Project Number 23038.005107/2011-83].Múltipla – ver em NotasHuman tuberculosis is an infectious disease caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). Although spoligotyping and MIRU-VNTR are standard methodologies in MTBC genetic epidemiology, recent studies suggest that Single Nucleotide Polymorphisms (SNP) are advantageous in phylogenetics and strain group/lineages identification. In this work we use a set of 79 SNPs to characterize 1987 MTBC isolates from Portugal and 141 from Northeast Brazil. All Brazilian samples were further characterized using spolygotyping. Phylogenetic analysis against a reference set revealed that about 95% of the isolates in both populations are singly attributed to bacterial lineage 4. Within this lineage, the most frequent strain groups in both Portugal and Brazil are LAM, followed by Haarlem and X. Contrary to these groups, strain group T showed a very different prevalence between Portugal (10%) and Brazil (1.5%). Spoligotype identification shows about 10% of mis-matches compared to the use of SNPs and a little more than 1% of strains unidentifiability. The mis-matches are observed in the most represented groups of our sample set (i.e., LAM and Haarlem) in almost the same proportion. Besides being more accurate in identifying strain groups/lineages, SNP-typing can also provide phylogenetic relationships between strain groups/lineages and, thus, indicate cases showing phylogenetic incongruence. Overall, the use of SNP-typing revealed striking similarities between MTBC populations from Portugal and Brazil

Avaliação sorológica para detecção de anticorpos anti-Leishmania em cães e gatos no bairro de Santa Rita de Cássia, Município de Barra Mansa, Estado do Rio de Janeiro Serological evaluation for detection of anti-Leishmania antibodies in dogs and cats in the district of Santa Rita de Cássia, municipality of Barra Mansa, State of Rio de Janeiro

A partir de um caso canino de leishmaniose tegumentar americana na localidade de Santa Rita de Cássia, município de Barra Mansa, Rio de Janeiro, foi realizado um inquérito sorológico em 177 cães e 43 gatos. Na avaliação das amostras de soros caninos, 10% foram positivos na reação de imunofluorescência indireta e 10,7% no ensaio imunoenzimático. Entre as amostras de soros felinos testados, nenhum animal foi positivo na reação de imunofluorescência indireta e apenas um (2,4%) felino apresentou reação positiva ao ensaio imunoenzimático. A detecção de Leishmania braziliensis, autóctone em Barra Mansa, faz um alerta para a instalação de um possível foco de leishmaniose tegumentar americana nessa região.<br>From a canine case of american cutaneous leishmaniasis in the locality of Santa Rita de Cássia, municipality of Barra Mansa, Rio de Janeiro, a serological survey was performed on 177 dogs and 43 cats. Evaluation of the canine serum samples showed that 10% had a positive reaction in the indirect immunofluorescence test and 10.7% in the enzyme-linked immunosorbent assay. Among the feline serum samples tested, none of the animals had a positive reaction in the indirect immunofluorescence test and only one (2.4%) showed a positive reaction in the enzyme-linked immunosorbent assay. The detection of an autochthonous case of Leishmania braziliensis in Barra Mansa gives warning that a focus of american cutaneous leishmaniasis is possibly becoming established in this region