Uso do WhatsApp em um grupo de educação em saúde com mulheres

Objetivo: Analisar o uso de Tecnologias de Informação e Comunicação e a interação em um grupo de educação em saúde com mulheres no WhatsApp.Metodologia: Pesquisa qualitativa com mães pertencentes a duas Unidades Básicas de Saúde de Sinop - MT incluídas em um Projeto de Extensão que utilizou estratégias educativas em saúde (“Dia G”, “Dicas em saúde” e “Vídeo Educativo”) e membros da equipe do projeto. Os dados foram coletados entre outubro-dezembro de 2021, a partir das mensagens no grupo de WhatsApp e submetidos à Análise de Conteúdo Temática.Resultados: Foram identificadas duas categorias, as quais mostram as informações disponibilizadas pela equipe e as solicitadas pelas mães pontualmente; que as dúvidas manifestadas pelas mães mobilizaram a comunicação-interação entre os participantes e que pouca ou nenhuma interação foi suscitada pelas informações de saúde contidas nas estratégias educativas utilizadas. Considerações finais: O WhatsApp mostrou-se como importante recurso/estratégia na comunicação-interação para educação em saúde com mulheres.Palavras-chave: Tecnologia da informação. Educação em saúde. Saúde da mulher. Atenção primária à saúde

PLUMBAGINALES: A PHARMACOLOGICAL APPROACH

ABSTRACT Plumbaginales belongs to the superorder Malviflorae and comprises two families, Plumbaginaceae and Limoniaceae. Its representatives are chemically characterized by the presence of naphthoquinones, flavonoids, terpenoids and steroids, many of them being the responsible for biodynamic activities. The extracts of some species of Plumbaginales and also some isolated compounds revealed to be of great importance in the search of new drugs, since they have been described in literature for the treatment of many diseases such as: leishmaniasis, Chagas' disease, malaria, cancer and others. Plants represent a valuable source of bioactive compounds and should be investigated, as a promise in the development of effective, ready available and lesscostly drug

INSETOS-PRAGAS EM MUDAS DE Hylocereus spp. (Cactaceae) NA PARAÍBA

Plantios de Hylocereus (Cactaceae) tem sido cada vez mais encontrados no semiárido brasileiro, pois apresentam adaptabilidade ecológica da região e alto valor comercial. Pragas nesta cultura agrícola em áreas do estado da Paraíba têm sido visualizadas e este trabalho tem como objetivo a sua identificação. Para tal foram coletadas plantas com tais injúrias e seus causadores em um viveiro de mudas, situado no Instituto Nacional do Semiárido (Campina Grande-PB). Para a classificação destes insetos foram utilizados material bibliográfico e microscopia. Foi constatada a primeira ocorrência de Schistocerca pallens (Thunberg) (Orthoptera: Acrididae) e Diaspis echinocacti (Bouché, 1833) (Hemiptera: Diaspididae) causando tais injúrias em plantas de Hylocereus spp. no estado da Paraíba (Brasil). A partir desta evidência, trabalhos para melhorar as condições de manejo desta praga desta cultura podem ser realizados levando em consideração as informações descritas neste manuscrito

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

Minimal Symptom Expression' in Patients With Acetylcholine Receptor Antibody-Positive Refractory Generalized Myasthenia Gravis Treated With Eculizumab

The efficacy and tolerability of eculizumab were assessed in REGAIN, a 26-week, phase 3, randomized, double-blind, placebo-controlled study in anti-acetylcholine receptor antibody-positive (AChR+) refractory generalized myasthenia gravis (gMG), and its open-label extension

O Serviço de documentação textual e iconografia do Museu Paulista

The essay compares the curatorship's works realized during the decade of 1990 by the actual Department of Textual and Iconographical Documentation of Museu Paulista, responsible for the MP Fund / Permanent File (Fundo MP/Arquivo Permanente), hundreds of collections and textual funds and 50.000 iconography pieces, great part of which are gathered in photographic collections. It shows how the documentation work extrapolates the limits of SVDHICO in order to integrate itself with the group activities of the museum and with other research groups. It also points towards new work methodologies which allow to perform the curatorship in an integrated way with the interdisciplinary research and the culture diffusion.O artigo faz um balanço dos trabalhos de curadoria realizados durante a década de 1990 pelo atual Serviço de Documentação Textual e Iconografia do Museu Paulista, responsável pelo Fundo MP/Arquivo Permanente, centenas de coleções e fundos textuais e 50.000 peças de iconografia, grande parte delas reunidas em coleções fotográficas. Mostra como o trabalho de documentação extrapola os limites do SVDHICO para integrar-se com as atividades de conjunto do Museu e com outros grupos de pesquisa. Aponta também para novas metodologias de trabalho com imagens que permitem realizar a curadoria de forma integrada à pesquisa interdisciplinar e à difusão cultural

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men