A submillimeter interference spectrometer - Characteristics, performance and measurements

Performance characteristics of interference spectrometer using submillimeter wave

Constrictive pericarditis and rheumatoid nodules with severe aortic incompetence.

The case of a female patient presenting with constrictive rheumatoid pericarditis and aortic incompetence secondary to valvular rheumatoid nodules is described along with a review of the literature with the aim to highlight this rare cause of aortic insufficiency

A ‘work in progress’?: UK researchers and participation in public engagement

The funders of UK research seek to embed public engagement by researchers within the culture of UK research. Within this context, this paper provides a snapshot of the UK public engagement landscape by reporting on new quantitative research that examines the experiences and perspectives of UK researchers (n = 2,454) and public engagement support staff (n = 260). The research suggests that ambitions to embed public engagement by researchers within institutional cultures can be understood as a 'work in progress'. There are indications that public engagement is part of the UK research landscape. At the same time, the research suggests that researchers' public engagement efforts are currently constrained; there is evidence of a disconnect between researchers themselves and broader institutional contexts of public engagement, and the sector is overwhelmingly driven by funding and rewards for research, teaching and other activities. In conclusion, these results indicate that, while current strategies have been helpful, longer term effort is required, perhaps targeting particular domains and, more fundamentally, perhaps featuring greater support and reward for public engagement

The Measurement of Medicaid Coverage in the SIPP: Evidence from California, 1990-1996

This paper studies the accuracy of reported Medicaid coverage in the Survey of Income and Program Participation (SIPP) using a unique data set formed by matching SIPP survey responses to administrative records from the State of California. Overall, we estimate that the SIPP underestimates Medicaid coverage in the California population by about 10 percent. Among SIPP respondents who can be matched to administrative records, we estimate that the probability someone reports Medicaid coverage in a month when they are actually covered is around 85 percent. The corresponding probability for low-income children is even higher - at least 90 percent. These estimates suggest that the SIPP provides reasonably accurate coverage reports for those who are actually in the Medicaid system. On the other hand, our estimate of the false positive rate (the rate of reported coverage for those who are not covered in the administrative records) is relatively high: 2.5 percent for the sample as a whole, and up to 20 percent for poor children. Some of this is due to errors in the recording of Social Security numbers in the administrative system, rather than to problems in the SIPP.

The Landscape of Realized Homologous Recombination in Pathogenic Bacteria

Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the emergence of pathogenicity. Here, we examined landscapes of realized homologous recombination of 500 genomes from ten bacterial species and found all species have “hot” regions with elevated rates relative to the genome average. We examined the size, gene content, and chromosomal features associated with these regions and the correlations between closely related species. The recombination landscape is variable and evolves rapidly. For example in Salmonella, only short regions of around 1 kb in length are hot whereas in the closely related species Escherichia coli, some hot regions exceed 100 kb, spanning many genes. Only Streptococcus pyogenes shows evidence for the positive correlation between GC content and recombination that has been reported for several eukaryotes. Genes with function related to the cell surface/membrane are often found in recombination hot regions but E. coli is the only species where genes annotated as “virulence associated” are consistently hotter. There is also evidence that some genes with “housekeeping” functions tend to be overrepresented in cold regions. For example, ribosomal proteins showed low recombination in all of the species. Among specific genes, transferrin-binding proteins are recombination hot in all three of the species in which they were found, and are subject to interspecies recombination

Development of autoclavable addition type polyimides

Two highly promising approaches to yield autoclavable addition-type polyimides were identified and evaluated in the program. Conditions were established for autoclave preparation of Hercules HMS graphite fiber reinforced composites in the temperature range of 473 K to 505 K under an applied pressure of 0.7 MN/m2 (100 psi) for time durations up to four hours. Upon oven postcure in air at 589 K, composite samples demonstrated high mechanical property retention at 561 K after isothermal aging in air for 1000 hours. Promise was shown for shorter term mechanical property retention at 589 K upon exposure in air at this temperature

Development of autoclavable polyimides

A poly(Diels-Alder) (PDA) resin approach was investigated as a means to achieve autoclavability of high temperature resistant resin/fiber composites under mild fabrication procedures. Low void content Type A-S graphite reinforced composites were autoclave fabricated from a PDA resin/fiber prepared from an acetone:methanol:dioxane varnish. Autoclave conditions were 477K (400F) and 0.7 MN/sq m (100 psi) for up to two hours duration. After postcure at temperatures up to 589K (600F), the composites demonstrated high initial mechanical properties at temperatures up to 561K (550F). The results from isothermal aging studies in air for 1000 hours indicated potential for long-term ( 1000 hours) use at 533K (500F) and shorter-term (up to 1000 hours) at 561K (550F)

Gene loss and lineage specific restriction-modification systems associated with niche differentiation in the Campylobacter jejuni Sequence Type 403 clonal complex

Campylobacter jejuni is a highly diverse species of bacteria commonly associated with infectious intestinal disease of humans and zoonotic carriage in poultry, cattle, pigs, and other animals. The species contains a large number of distinct clonal complexes that vary from host generalist lineages commonly found in poultry, livestock, and human disease cases to host-adapted specialized lineages primarily associated with livestock or poultry. Here, we present novel data on the ST403 clonal complex of C. jejuni, a lineage that has not been reported in avian hosts. Our data show that the lineage exhibits a distinctive pattern of intralineage recombination that is accompanied by the presence of lineage-specific restriction-modification systems. Furthermore, we show that the ST403 complex has undergone gene decay at a number of loci. Our data provide a putative link between the lack of association with avian hosts of C. jejuni ST403 and both gene gain and gene loss through nonsense mutations in coding sequences of genes, resulting in pseudogene formation

Experiences of evidence presentation in court: an insight into the practice of crime scene examiners in England, Wales and Australia

Background: The ability to present complex forensic evidence in a courtroom in a manner that is fully comprehensible to all stakeholders remains problematic. Individual subjective interpretations may impede a collective and correct understanding of the complex environments and the evidence therein presented to them. This is not fully facilitated or assisted in any way with current non-technological evidence presentation methods such as poor resolution black and white photocopies or unidimensional photographs of complex 3D environments. Given the wide availability of relatively cheap technology, such as tablets, smartphones and laptops, there is evidence to suggest that individuals are already used to receiving visually complex information in relatively short periods of time such as is available in a court hearing. courtrooms could learn from this more generic widespread use of technology and have demonstrated their ability to do so in part by their adoption of the use of tablets for Magistrates. The aim of this current study was to identify the types of digital technology being used in courts and to obtain data from police personnel presenting digital evidence in court. Results: A questionnaire study was conducted in this research to explore current technology used within courtrooms from the perspective of crime scene personnel involved in the presentation of complex crime scene evidence. The study demonstrated that whilst many of the participants currently utilize high-end technological solutions to document their crime scenes, such as 360° photography or laser scanning technologies, their ability to present such evidence was hindered or prevented. This was most likely due to either a lack of existing technology installed in the court, or due to a lack of interoperability between new and existing technology. Conclusion: This study has contributed to this academic field by publishing real life experiences of crime scene examiner’s, who have used advanced technology to record and evaluate crime scenes but are limited in their scope for sharing this information with the court due to technological insufficiency. Contemporary recording techniques have provided the opportunity for further review of crime scenes, which is considered to be a valuable property over previous documentation practice, which relied upon the competency of the investigator to comprehensively capture the scene, often in a single opportunity