No demonstrable association between the Leningrad–Zagreb mumps vaccine strain and aseptic meningitis in a large clinical trial in Egypt

AbstractTo address the claim that the Leningrad–Zagreb (L-Z) mumps vaccine strain is causally associated with aseptic meningitis, a prospective, post-marketing safety study was conducted with a measles-mumps-rubella vaccine (MMR) (TRESIVAC°; Serum Institute of India Ltd., Pune, India), which uses the L-Z strain as its mumps component in Egypt. In all, 453 119 children (65 423 children aged 16–24 months and 329 211 children aged 5–7 years) received MMR. The control groups which, as a result of local health regulations, were slightly younger than vaccinees, comprised 12 253 and 46 232 children, respectively. Using questionnaires, the parents recorded solicited local, systemic and neurological adverse events for up to 42 days post-vaccination. All data were analysed externally on an intention-to-treat basis by individuals not participating in the study. Local and/or systemic reactions were reported in a small percentage of participants, with pain, fever and parotitis being the most common signs among vaccinees in both age groups. No case of aseptic meningitis, encephalitis, anaphylaxis or convulsions was observed in any participant. Thus, in this series of more than 450 000 Egyptian children, the L-Z mumps vaccine strain in this vaccine did not cause aseptic meningitis. The vaccine is considerably cheaper than Western competitors and a valid alternative to other MMR vaccines

Study of Photoluminescence Behaviour of Porous Silicon Samples Prepared at 20 mA Current Density

The paper presents a study on a series of porous silicon films of various thicknesses, prepared at 20 mA current density using a photoluminescence fitting model to determine the average crystallite size of sphe-rical shaped interconnected silicon quantum dots. Discrepancy in photoluminescence behavior of the samples is well explained with this model. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3097

Electronic Conduction in Annealed Sulfur-Doped a-Si:H Films

In present work, the effect of annealing on dark and photo conductivity as well as the various causes of conduction mechanics in S doped amorphous hydrogenated silicon films (a-Si:H) is discussed. The variation of the dark conductivity as a function of temperature has been carried out on unannealed and annealed (annealed at an optimized temperature of 300 °C) thin film samples and the activation energy of dark conductivity of respective samples was also calculated at different temperatures. The Study concludes that at high temperatures, an activated type mechanism is responsible for conduction in the a-Si:H films

A new approach to social behavior simulation: the mask model

This paper proposes a new perspective, based on the concept of social masks, for the simulation of a realistic NPC (Non-Player Character) behavior. The Mask Model goal is to support AI techniques for autonomous agents by encouraging or discouraging behaviors according to the social environment and by providing knowledge about possible reactions to the agent actions. In this approach, the NPC tendencies are controlled by the interactions of three overlapping mask layers: self- perception layer, social layer and interpersonal layer. The masks mould the tendencies, the feelings and the ethics of a NPC. By changing the links between characters and masks, a wide variety of different behaviors and story-lines may arise. The paper present an algorithm for the selection of the actions and an example implementation

Deployment of genetic and genomic tools toward gaining a better understanding of Rice-Xanthomonasoryzae pv. oryzae interactions for development of durable bacterial blight resistant rice

Rice is the most important food crop worldwide and sustainable rice production is important for ensuring global food security. Biotic stresses limit rice production significantly and among them, bacterial blight (BB) disease caused by Xanthomonas oryzae pv. oryzae (Xoo) is very important. BB reduces rice yields severely in the highly productive irrigated and rainfed lowland ecosystems and in recent years; the disease is spreading fast to other rice growing ecosystems as well. Being a vascular pathogen, Xoo interferes with a range of physiological and biochemical exchange processes in rice. The response of rice to Xoo involves specific interactions between resistance (R) genes of rice and avirulence (Avr) genes of Xoo, covering most of the resistance genes except the recessive ones. The genetic basis of resistance to BB in rice has been studied intensively, and at least 44 genes conferring resistance to BB have been identified, and many resistant rice cultivars and hybrids have been developed and released worldwide. However, the existence and emergence of new virulent isolates of Xoo in the realm of a rapidly changing climate necessitates identification of novel broad-spectrum resistance genes and intensification of gene-deployment strategies. This review discusses about the origin and occurrence of BB in rice, interactions between Xoo and rice, the important roles of resistance genes in plant’s defense response, the contribution of rice resistance genes toward development of disease resistance varieties, identification and characterization of novel, and broad-spectrum BB resistance genes from wild species of Oryza and also presents a perspective on potential strategies to achieve the goal of sustainable disease management

Spin Fidelity for Three-qubit Greenberger-Horne-Zeilinger and W States Under Lorentz Transformations

Constructing the reduced density matrix for a system of three massive spin$-\frac{1}{2}$ particles described by a wave packet with Gaussian momentum distribution and a spin part in the form of GHZ or W state, the fidelity for the spin part of the system is investigated from the viewpoint of moving observers in the jargon of special relativity. Using a numerical approach, it turns out that by increasing the boost speed, the spin fidelity decreases and reaches to a non-zero asymptotic value that depends on the momentum distribution and the amount of momentum entanglement.Comment: 12pages, 2 figure

Direct and indirect contacts between cattle farms in north-west England

Little is known regarding the types and frequencies of contact that exist between farms and which of these may act as pathogen transmission routes; however it is likely that farms demonstrate considerable heterogeneity in such contacts. In this cross-sectional study, we explored the direct and indirect contact types and frequencies that exist between cattle farms within a region, focusing on potential routes of pathogen transmission. The owners/managers of 56 farms located in a 10 km by 10 km study area in north-west England were administered an interview-based questionnaire between June and September 2005. Information was obtained relating to contact types and frequencies, including those involving animal movements, equipment sharing between farms and any contractors or companies visiting the farms. The data was explored using hierarchical cluster analysis and network analysis. There was considerable variation between farms arising from different contact types. Some networks exhibited great connectivity, incorporating approximately 90% of the farms interviewed in a single component, whilst other networks were more fragmented, with multiple small components (sets of connected farms not linked with other farms). A range of factors influencing contact between farms were identified. For example, contiguous farms were more likely to be linked via other contacts, such as sharing of equipment and direct farm-to-farm animal movements (p < 0.001 and p = 0.02, respectively). The frequency of contacts was also investigated; it is likely that the amount of contact a farm receives from a company or contractor and whether or not biosecurity is performed after contact would impact on disease transmission potential. We found considerable heterogeneity in contact frequency and that many company and contractor personnel undertook little biosecurity. These findings lead to greater understanding of inter-farm contact and may aid development of appropriate biosecurity practices and control procedures, and inform mathematical modelling of infectious diseases

HiFlo-DAT: Indian Himalayan Flood Database, for Disaster Risk Reduction in the Kullu District

‘HiFlo-DAT’ is an ongoing bi-lateral research project (UK and India, UGC-UKIERI funded, 2018-2020), focussing on historical floods in the Kullu District, Himachal Pradesh, Indian Himalaya. The project team, comprising academic and state/district disaster management authorities, are together developing a new historical flood hazard database as a foundation for improved disaster risk management functions in the region. This is necessary as current management relies on incomplete knowledge of past flood event occurrence, bringing elevated exposure/ risk to development. The HiFlo-DAT database provides a step-change, drawing on extensive mining of archive materials held in private and public collections in India, UK and USA. These materials include newspapers, government reports/ registers, diaries, books, academic articles etc. Most extensive are English language Indian region newspapers, of which we have amassed overlapping holdings over 184 years (1835 to present), totalling c. 150,000 pages. Our acquisition includes coverage of annual periods where publications are digitally searchable (e.g. The Tribune, The Times of India, The Indian Express). In contrast, where archives remain in an analogue microfilm format (e.g. The Civil and Military Gazette, The Friend of India) we restricted data searches to monsoon season months (i.e. July to September) given this is the typical window for floods in the Western Himalaya. The HiFlo-DAT database architecture takes account of best practice, having systematically reviewed global (most commonly European) flood database research in the last c. 30 years, in regard to database structure, data entry/verification protocols, analytical foci and societal impact. HiFlo-DAT has 103 possible entry categories for each event record, which are aggregated into 11 principal groups (i.e. database management, citation information, timing/ duration, location, causation and hydro-meteorological magnitude, channel/ catchment geomorphological impacts, damage/ destruction/ costs, human casualties, pre-event actions, event response, post-event actions). The bi-lateral review of source materials and population of the database are governed by an agreed set of protocols. Initial analyses are focussing on: (1) event spatial/ temporal/ impact signatures; (2) the relationship between flood occurrence and rainfall conditions. The latter makes use of a unique long-term daily rainfall series for Naggar Farm, being compiled from British government records (1891-1950) and current IARI data (1962 to present). HiFlo-DAT is designed with capacity for future updating, and will be open access via the BathSPAdata repository and HPSDMA website

Effect of Mill Type on Morphology of AA6013 Aluminium Powder

ABSTRACTIn conventional recycling method, metal chips are cast after pressing and melting in electric arc furnace. Material loss occurs during the recycling from liquid metal due to the several reasons. Direct recycling method which produces the aluminium powder from aluminium chips using mechanical mill can be an alternative to conventional recycling method. Thus material and energy losses, and labour cost will be reduced by direct recycling method without melting.In this study, the particle morphology of powder direct recycled from AA6013 aluminium alloy chips with cryogenic, disc and ball type grinders is investigated. Mechanical milling resulted flaky and irregular shaped AA6013 particles. It was ascertained that the chips did not break sufficiently in despite of the long duration milling mechanisms by ball mill. Cryogenic mill provides the energy required for milling mechanisms to act. Disc mill has the highest impact energy was determined. Consequently, efficiency of ball mill is lower than the efficiency of cryogenic and disc type mills. Shape factors of powders produced with ball and cryogenic mills were found greater than that of the powder produced by disc mill. Disc mill has the most efficient and effective impact energy which produces the smaller particles per minute, was determined.Keywords: Direct recycling method, powder production, scrap chips, aluminium alloy.