Bound Energy Masses of Mesons Containing the Fourth Generation and Iso-singlet Quarks

The fourth Standard Model (SM) family quarks and weak iso-singlet quarks The fourth Standard Model (SM) family quarks and weak iso-singlet quarks predicted by ${\rm E}_{6\text{}}$ GUT are considered. The spin-average of the pseudoscalar $\eta_{4}(n^{1}S_{0})$ and vector $\psi_{4}(n^{3}S_{1})$ quarkonium binding masses of the new mesons formed by the fourth Standard Model (SM) family and iso-singlet ${\rm E}_{6\text{}}$ with their mixings to ordinary quarks are investigated. Further, the fine and hyperfine mass splittings of the these states are also calculated. We solved the Schr\"{o}dinger equation with logarithmic and Martin potentials using the Shifted large-${\rm N}$ expansion technique. Our results are compared with other models to gauge the reliability of the predictions and point out differences.Comment: 13 page

Path Integral Solution of PT-/non-PT-Symmetric and non-Hermitian Hulthen Potential

The wave functions and the energy spectrum of PT-/non-PT-Symmetric and non-Hermitian Hulthen potential are of an exponential type and are obtained via the path integral. The path integral is constructed using parametric time and point transformation

Non-commutative holography and scattering amplitudes in a large magnetic background

We study planar gluon scattering amplitudes and Wilson loops in non-commutative gauge theory. Our main results are: 1. We find the map between observables in non-commutative gauge theory and their holographic dual. In that map, the region near the boundary of the gravitational dual describes the physics in terms of T-dual variables. 2. We show that in the presence of a large magnetic background and a UV regulator, a planar gluon scattering amplitude reduces to a complex polygon Wilson loop expectation value, dressed by a tractable polarization dependent factor.Comment: 26 pages. v2: corrected section 4, reference adde

ASCORE: an up-to-date cardiovascular risk score for hypertensive patients reflecting contemporary clinical practice developed using the (ASCOT-BPLA) trial data.

A number of risk scores already exist to predict cardiovascular (CV) events. However, scores developed with data collected some time ago might not accurately predict the CV risk of contemporary hypertensive patients that benefit from more modern treatments and management. Using data from the randomised clinical trial Anglo-Scandinavian Cardiac Outcomes Trial-BPLA, with 15 955 hypertensive patients without previous CV disease receiving contemporary preventive CV management, we developed a new risk score predicting the 5-year risk of a first CV event (CV death, myocardial infarction or stroke). Cox proportional hazard models were used to develop a risk equation from baseline predictors. The final risk model (ASCORE) included age, sex, smoking, diabetes, previous blood pressure (BP) treatment, systolic BP, total cholesterol, high-density lipoprotein-cholesterol, fasting glucose and creatinine baseline variables. A simplified model (ASCORE-S) excluding laboratory variables was also derived. Both models showed very good internal validity. User-friendly integer score tables are reported for both models. Applying the latest Framingham risk score to our data significantly overpredicted the observed 5-year risk of the composite CV outcome. We conclude that risk scores derived using older databases (such as Framingham) may overestimate the CV risk of patients receiving current BP treatments; therefore, 'updated' risk scores are needed for current patients

Three-point function of semiclassical states at weak coupling

We give the derivation of the previously announced analytic expression for the correlation function of three heavy non-BPS operators in N=4 super-Yang-Mills theory at weak coupling. The three operators belong to three different su(2) sectors and are dual to three classical strings moving on the sphere. Our computation is based on the reformulation of the problem in terms of the Bethe Ansatz for periodic XXX spin-1/2 chains. In these terms the three operators are described by long-wave-length excitations over the ferromagnetic vacuum, for which the number of the overturned spins is a finite fraction of the length of the chain, and the classical limit is known as the Sutherland limit. Technically our main result is a factorized operator expression for the scalar product of two Bethe states. The derivation is based on a fermionic representation of Slavnov's determinant formula, and a subsequent bosonisation.Comment: 28 pages, 5 figures, cosmetic changes and more typos corrected in v

Bound-States of the Spinless Salpeter Equation for the PT-Symmetric Generalized Hulthen Potential by the Nikiforov-Uvarov Method

The one-dimensional spinless Salpeter equation has been solved for the PT-symmetric generalized Hulth\'{e}n potential. The Nikiforov-Uvarov {NU) method which is based on solving the second-order linear differential equations by reduction to a generalized equation of hypergeometric type is used to obtain exact energy eigenvalues and corresponding eigenfunctions. We have investigated the positive and negative exact bound states of the s-states for different types of complex generalized Hulthen potentials.Comment: 24 page

Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial

<p><b>Aims:</b> We tested whether on-statin C-reactive protein is associated with cardiovascular (CV) outcome in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).</p> <p><b>Methods and results:</b> ASCOT randomized a subset of 4853 patients with total cholesterol ≤6.5 mmol/L (250 mg/dL) to atorvastatin or placebo. In a case–control study during 5.5-year follow-up, 485 CV cases were age- and sex-matched with 1367 controls. Baseline LDL-cholesterol (LDL-c) and log-transformed C-reactive protein predicted CV events [odds ratio (OR) per 1 standard deviation (SD) 1.31 (95% confidence interval {CI}: 1.10, 1.56), P = 0.002 and OR 1.19 (1.05, 1.34), P = 0.006, respectively]. Including baseline C-reactive protein into a Framingham risk model very modestly improved risk prediction. Baseline C-reactive protein did not indicate the magnitude of the atorvastatin effect on CV outcome (P = 0.54). At 6 months, atorvastatin reduced median LDL-c by 40.3% and median C-reactive protein by 27.4%. In those randomized to atorvastatin, lower on-treatment LDL-c at 6 months was associated with a significant reduction in subsequent CV events [OR 0.41 (0.22, 0.75), P = 0.004] comparing those above and below the median (2.1 mmol/L). In contrast, C-reactive protein below the median (1.83 mg/L) compared with C-reactive protein above the median was not associated with a significant reduction in CV events [OR 0.86 (0.49, 1.51), P = 0.60]. Consequently, addition of on-treatment C-reactive protein to LDL-c did not improve prediction of statin efficacy.</p> <p><b>Conclusion:</b> Among these hypertensive patients selected on the basis of traditional CV risk factors, C-reactive protein did not usefully improve the prediction of CV events and, critically, reduction in C-reactive protein associated with statin therapy was not a predictor of CV outcome alone or in combination with LDL-c.</p&gt

An exact formula for the radiation of a moving quark in N=4 super Yang Mills

We derive an exact formula for the cusp anomalous dimension at small angles. This is done by relating the latter to the computation of certain 1/8 BPS Wilson loops which was performed by supersymmetric localization. This function of the coupling also determines the power emitted by a moving quark in N=4 super Yang Mills, as well as the coefficient of the two point function of the displacement operator on the Wilson loop. By a similar method we compute the near BPS expansion of the generalized cusp anomalous dimension.Comment: 22 pages, 5 figures. v2: references added, typos correcte

When the Earth trembles in the americas: the experience of haiti and chile 2010.

The response of the nephrological community to the Haiti and Chile earthquakes which occurred in the first months of 2010 is described. In Haiti, renal support was organized by the Renal Disaster Relief Task Force (RDRTF) of the International Society of Nephrology (ISN) in close collaboration with Médecins Sans Frontières (MSF), and covered both patients with acute kidney injury (AKI) and patients with chronic kidney disease (CKD). The majority of AKI patients (19/27) suffered from crush syndrome and recovered their kidney function. The remaining 8 patients with AKI showed acute-to-chronic renal failure with very low recovery rates. The intervention of the RDRTF-ISN involved 25 volunteers of 9 nationalities, lasted exactly 2 months, and was characterized by major organizational difficulties and problems to create awareness among other rescue teams regarding the availability of dialysis possibilities. Part of the Haitian patients with AKI reached the Dominican Republic (DR) and received their therapy there. The nephrological community in the DR was able to cope with this extra patient load. In both Haiti and the DR, dialysis treatment was able to be prevented in at least 40 patients by screening and adequate fluid administration. Since laboratory facilities were destroyed in Port-au-Prince and were thus lacking during the first weeks of the intervention, the use from the very beginning on of a point-of-care device (i-STAT®) was very efficient for the detection of aberrant kidney function and electrolyte parameters. In Chile, nephrological problems were essentially related to difficulties delivering dialysis treatment to CKD patients, due to the damage to several units. This necessitated the reallocation of patients and the adaptation of their schedules. The problems could be handled by the local nephrologists. These observations illustrate that local and international preparedness might be life-saving if renal problems occur in earthquake circumstances