544 research outputs found
Las competencias sociales y los indicadores en Ingeniería
La rapidez actual con que se desarrollan los adelantos en I + D + i (Investigación, Desarrollo más innovación) implica la formación de ingenieros con un nuevo rol en el mundo. En este contexto, la formación por competencias es un eje central en el debate académico actual en la formación de nuevos graduados.
La bibliografía existente en el tema de la competencia sostiene que es un escenario complejo que fundamenta un cambio en los diferentes modelos educativos en busca del aporte de diferentes metodologías de enseñanzas constructivistas que privilegien al alumno en el centro del proceso en la construcción y aplicación del aprendizaje.
Por un lado, se pone mucho énfasis en la integridad de los saberes científicos tecnológicos- sociales y valores donde se acentúa la capacidad de saber usar dichos conocimientos para resolver situaciones profesionales reales.
El objetivo de esta ponencia es demostrar que, si bien están consideradas en los planes de estudio asignaturas de índole social y ético también llamadas “materias complementarias”, su grado de relevancia y alcance debería redefinirse y adoptarse el significado de competencias anteriormente considerado.
También se propone la confección de indicadores básicos que permitan medir la capacidad de diferentes competencias que se encuentran insertas en el desarrollo curricular de la ingeniería.
Se parte de la aplicación de indicadores en la formación de ingenieros.
El tipo de diseño es cualitativo.The actual speed at which advances in R + D + i (Research, Development More Innovation) implications Engineering Education with UN new role in the world are developed. In this context, skills training is the central axis of the UN in the real academic debate on the formation of new graduates.
The existing literature on the subject of competition Competition is a complex scenario based UN Educational Change in Different Models in search of the contribution of different methodologies that favor Constructivist Teaching students with the center of the process in the construction and application Learning.
On one hand, it puts much emphasis on the integrity of scientific knowledge and technological- social values and the ability to use the saber is accentuated paragraph such knowledge to solve real business situations.
The Objective of This paper is to show that, although they are considered in the curricula subjects social, and ethical also calls “complementary subjects”, the degree of relevance and scope of them should be taken redefined the meaning of competence previously considered.
Also making Basic indicators to measure the ability of different competencies that are embedded in the curriculum of engineering is proposed
Aprendizaje centrado en el alumno en Ciencias Básicas
El trabajo se basó en la utilización de diferentes técnicas que se aplican en el curso de nivelación de la Universidad Nacional A.J. en la asignatura Matemática de Ciencias Básicas para nivelar los conocimientos de los alumnos en el ingreso a la universidad durante el año 2019. En la evaluación de nivelación se tiene en cuenta el desarrollo de diferentes rubricas de acuerdo a lo solicitado en el Libro Rojo de CONFEDI. Se aplicó una metodología detallada donde se integran diferentes elementos que permiten identificar el análisis cualitativo y cuantitativo comparando diferentes variables que se encuentran presentes en la aplicación del aprendizaje centrado en el alumno evaluando las competencias aplicadas, procediendo a validar la muestra con los resultados obtenidos. El diseño utilizado es cuantitativo / cualitativo.Red de Universidades con Carreras en Informátic
Evaluación de Competencias a través de una Experiencia de Flipped Classrom en Programación en la Universidad Nacional de La Matanza
El objetivo general de la investigación ha sido la utilización de diferentes herramientas de lenguajes de programación con la utilización de Flpped Classroom en la Universidad Nacional de la Matanza en Asignatura de Programación favoreciendo la aplicación y evaluación de competencias.
A partir de esa finalidad se ha propuesto crear los recursos y materiales necesarios para poder desarrollar una experiencia de “Flipped Classroom” para los cursos durante el año 2013-2016 y promover el uso de FlippedClasroom que es una metodología educativa que implica “dar la vuelta a la clase”.
Se parte de la Hipótesis: La aplicación de Flipped Classroom en estudiantes de la carrera de Ingeniería en Informática de la Universidad Nacional de la Matanza favorece la aplicación y evaluación de competencias del alumno en la Asignatura Programación. El tipo de diseño es cuantitativo / cualitativo. Por último se procede a validar la muestra con los resultados obtenidos
Role of ACE2 genetic polymorphisms in susceptibility to SARS-CoV-2 among highly exposed but non infected healthcare workers
We aim to evaluate the role of single-nucleotide polymorphisms of the angiotensin-converting enzyme 2 in susceptibility to SARS-CoV-2 infection. We included 28 uninfected but highly exposed healthcare workers and 39 hospitalized patients with COVID-19. Thirty-five SNPs were rationally selected. Two variants were associated with increased risk of being susceptible to SARS-CoV-2: the minor A allele in the rs2106806 variant (OR 3.75 [95% CI 1.23-11.43]) and the minor T allele in the rs6629110 variant (OR 3.39 [95% CI 1.09-10.56]). Evaluating the role of genetic variants in susceptibility to SARS-CoV-2 infection could help identify more vulnerable individuals and suggest potential drug targets for COVID-19 patients.This work was supported by Instituto de Salud Carlos III: [grant number AC17/00019,COV20/00349,PI18/00154,PT17/0019]; Merck, Sharp & Dohme: [Ref IISP 59181].S
Total Zn of foods and bioaccesible fractions in the small and large intestine after in vitro digestion and fermentation with fecal material of healthy adults and children: Influence of culinary techniques
This work was supported by the European Research Commission
(Research Executive Agency) under the research project Stance4Health
under Grant Contract No 816303 and by the Plan propio de Investigación
y Transferencia of the University of Granada under the program
“Intensificación de la Investigación, modalidad B”.The healthy status of human beings is associated with an appropriate nutritional status in Zn, which must firstly be bioavailable. We measured the total Zn amount and its bioaccesibility in raw foods and after cooking by common culinary techniques. These foods were submitted to an in vitro digestion and fermentation with faecal inocula from healthy adults and children to evaluate Zn bioaccesibility in the small and large intestine. Mean total Zn amount provided by foods was 8.080 μg/g. Zn amount released from food in the small intestine was significantly different among several food groups and lower in raw vegetal foods compared to cooked ones (frying, roasting and grilling; p < 0.05); the same behaviour was found in the large intestine for healthy children. Zn bioaccesibility in the large intestine varied statistically according to the subjects’ idiosyncrasies, and was higher in healthy children (p < 0.05) probably due to growth demands and different composition of the colonic microbiota. In healthy adults and children, the bioaccesible fractions were 33.0 ± 20.4 % for the small intestine, 16.4 ± 22.0 and 59.6 ± 29.9% for the large one, and the non-bioaccessible ones 50.6 ± 19.9 and 7.4 ± 9.1%, respectively.European Research Commission
816303Plan propio de Investigación y Transferencia of the University of GranadaUniversidad de Granada
UG
Selenium bioaccesibility after in vitro digestion/fermentation of foods differs in adults and children
Selenium (Se) as essential element regulates the immune, endocrine, reproductive and neurological systems
through selenoproteins. More important than its content, is the fraction available to be absorbed (bioaccesibility)
to exert its important metabolic functions. The objective of this study was to determine the bioaccessibility of Se
(Se-BA) in multiple foods by an in vitro digestion/fermentation method. Samples were subjected to homemade
culinary techniques and fermented with feces from healthy adults (HE-AD), and healthy (HE-CH) and unhealthy
children (with gluten related disorders, GRD-CH; obesity, OB-CH; or allergy/intolerance to cow’s milk proteins,
AICM-CH). Se-BA varied largely among samples depending on their vegetal/animal origin, category and type of
food. Animal-vs. plant-based foods have higher mean Se concentration and total Se-BA (82.5(±97.5) and 93.6
(±8.58) vs. 44.3(±55.6) μg/kg and 77.7(±20.4)%, respectively). In plant-based foods, higher Se-BA values were
found in the large intestine (41.0(±25.7) vs. 30.1(±26.7%) in animal-base foods). In comparison to raw foods,
the cooking techniques of vegetal- and animal-based foods grouped by heating in liquid media (frying-boiling) or
hot air (roasting-grilling) decrease Se-BA in the small intestine (42.5(±27.0) vs. 34.8(±25.1) and 34.0(±24.3),
and 75.9(±38.0) vs. 52.4(±28.9) and 71.3(±24.8)%, respectively), while it is increased in the large intestine
(36.6(±28.5) vs. 41.3(±24.9) and 44.2(±23.6), and 19.9(±30.4) vs. 39.9(±26.0) and 23.4(±22.7)%, respec tively). The higher Se-BA levels in the large intestine found in HE-CH (42.1 (±26.5) vs. HE-AD (35.2(±27.1) and
unhealthy children (GRD-CH and OB-CH; 38.0(±24.6) and 35.8(±28.1)%, respectively) could be related to
greater demands on growth and specific fermentative microbiota.AGR-295 Alimentación y microbiota intestinal: relación con los alimentos y su procesado (Foodmicrogut
Multipactor mitigation in coaxial lines by means of permanent magnets
The main aim of this paper is the analysis of the
feasibility of employing permanent magnets for the multipactor
mitigation in a coaxial waveguide. First, the study of a coaxial
line immersed in a uniform axial magnetic field shows that multipactor
can be suppressed at any RF if the external magnetic field
is strong enough. Both theoretical simulations and experimental
tests validate this statement. Next, multipactor breakdown of a
coaxial line immersed in a hollow cylindrical permanent magnet
is analyzed. Numerical simulations show that multipactor can be
suppressed in a certain RF range. The performed experimental
test campaign demonstrates the capability of the magnet to avoid
the multipactor electron multiplication process.This work was supported by the European Regional Development Fund-A Way of Making Europe. The review of this paper was arranged by Editor R. Carter.Gonzalez Iglesias, D.; Pérez Pastor, AM.; Anza Hormigo, S.; Vague Cardona, JJ.; Gimeno Martinez, B.; Boria Esbert, VE.; Raboso García-Baquero, D.... (2014). Multipactor mitigation in coaxial lines by means of permanent magnets. IEEE Transactions on Electron Devices. 61(12):4224-4231. doi:10.1109/TED.2014.2361172S42244231611
Engaging stakeholders across a socio-environmentally diverse network of water research sites in North and South America
Maintaining and restoring freshwater ecosystem services in the face of local and global change requires adaptive research that effectively engages stakeholders. However, there is a lack of understanding and consensus in the research community regarding where, when, and which stakeholders should be engaged and what kind of researcher should do the engaging (e.g., physical, ecological, or social scientists). This paper explores stakeholder engagement across a developing network of aquatic research sites in North and South America with wide ranging cultural norms, social values, resource management paradigms, and eco-physical conditions. With seven sites in six countries, we found different degrees of engagement were explained by differences in the interests of the stakeholders given the history and perceived urgency of water resource problems as well as differences in the capacities of the site teams to effectively engage given their expertise and resources. We categorized engagement activities and applied Hurlbert and Gupta's split ladder of participation to better understand site differences and distill lessons learned for planning comparative socio-hydrological research and systematic evaluations of the effectiveness of stakeholder engagement approaches. We recommend research networks practice deliberate engagement of stakeholders that adaptively accounts for variations and changes in local socio-hydrologic conditions. This, in turn, requires further efforts to foster the development of well-integrated research teams that attract and retain researchers from multiple social science disciplines and enable training on effective engagement strategies for diverse conditions.Fil: Smyth, Robyn L.. Bard College; Estados UnidosFil: Fatima, Uroosa. Bard College; Estados UnidosFil: Segarra, Monique. Bard College; Estados UnidosFil: Borre, Lisa. Cary Institute of Ecosystem Studies; Estados UnidosFil: Zilio, Mariana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Económicas y Sociales del Sur. Universidad Nacional del Sur. Departamento de Economía. Instituto de Investigaciones Económicas y Sociales del Sur; ArgentinaFil: Reid, Brian. Universidad Austral de Chile; ChileFil: Pincetl, Stephanie. Institute of the Environment and Sustainability; Estados UnidosFil: Astorga, Anna. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Económicas y Sociales del Sur. Universidad Nacional del Sur. Departamento de Economía. Instituto de Investigaciones Económicas y Sociales del Sur; ArgentinaFil: Huamantinco Cisneros, María Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca; Argentina. Universidad Nacional del Sur. Departamento de Geografía y Turismo; ArgentinaFil: Conde, Sergio Daniel. Universidad de la República; UruguayFil: Harmon, Thomas Christopher. University of California Merced; Estados UnidosFil: Hoyos, Natalia. Universidad del Norte; ColombiaFil: Escobar, Jaime. Universidad del Norte; Colombia. Smithsonian Tropical Research Institute; PanamáFil: Lozoya, Juan Pablo. Universidad de la República; UruguayFil: Perillo, Gerardo Miguel E.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Argentino de Oceanografía. Universidad Nacional del Sur. Instituto Argentino de Oceanografía; Argentina. Universidad Nacional del Sur. Departamento de Geología; ArgentinaFil: Piccolo, Maria Cintia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Argentino de Oceanografía. Universidad Nacional del Sur. Instituto Argentino de Oceanografía; Argentina. Universidad Nacional del Sur. Departamento de Geografía y Turismo; ArgentinaFil: Rusak, James A.. Dorset Environmental Science Centre; Canadá. Queens University; CanadáFil: Velez, Maria I.. University of Regina; Canad
Differences in saliva ACE2 activity among infected and non-infected adult and pediatric population exposed to SARS-CoV-2
Background
Variations in the ACE2 activity in saliva could explain the striking differences of susceptibility to infection and risk of severe disease.
Methods
We analyze the activity of ACE2 in saliva in different population groups across a wide age range and disease status during April to June 2020, before SARS-CoV-2 vaccine implementation, and we establish differences between infected people and participants considered resistant (highly exposed healthcare workers and children who cohabited with parents with COVID-19 without isolation and remain IgG negative).
Results
We included 74 adults, of which 47 (64%) were susceptible and 27 (36%) were resistant, and 79 children, of which 41 (52%) were susceptible and 38 (48%) were resistant. Resistant adults have significantly lower ACE2 activity in saliva than susceptible adults and non-significant higher values than susceptible and resistant children. ACE2 activity is similar in the susceptible and resistant pediatric population (p = 0.527). In contrast, we observe an increase in activity as the disease's severity increases among the adult population (mild disease vs. severe disease, 39 vs. 105 FU, p = 0.039; severe disease vs. resistant, 105 vs. 31 FU, p < 0.001).
Conclusions
using an enzymatic test, we show that ACE2 activity in saliva correlates with the susceptibility to SARS-Cov-2 infection and disease severity. Children and adults with low-susceptibility to SARS-Cov-2 infection showed the lowest ACE2 activity. These findings could inform future strategies to identify at-risk individuals.This work was supported by Instituto de Salud Carlos III (AC17/00019, PI18/00154, COV20/00349, ICI20/00058), CRUE-Supera COVID, cofinanced by the European Development Regional Fund ‘‘A way to achieve Europe’’ (ERDF), Merck, Sharp & Dohme Investigator Studies Program (code MISP# IIS 60257), Fondo Supera COVID-19 (2020-001), and SEIMC (becas SEIMC).Peer reviewe
- …