100 research outputs found

    Holographic Multiverse

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    We explore the idea that the dynamics of the inflationary multiverse is encoded in its future boundary, where it is described by a lower dimensional theory which is conformally invariant in the UV. We propose that a measure for the multiverse, which is needed in order to extract quantitative probabilistic predictions, can be derived in terms of the boundary theory by imposing a UV cutoff. In the inflationary bulk, this is closely related (though not identical) to the so-called scale factor cutoff measure.Comment: 23 pages, 4 figures. Replaced to match published versio

    CP and Lepton-Number Violation in GUT Neutrino Models with Abelian Flavour Symmetries

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    We study the possible magnitudes of CP and lepton-number-violating quantities in specific GUT models of massive neutrinos with different Abelian flavour groups, taking into account experimental constraints and requiring successful leptogenesis. We discuss SU(5) and flipped SU(5) models that are consistent with the present data on neutrino mixing and upper limits on the violations of charged-lepton flavours and explore their predictions for the CP-violating oscillation and Majorana phases. In particular, we discuss string-derived flipped SU(5) models with selection rules that modify the GUT structure and provide additional constraints on the operators, which are able to account for the magnitudes of some of the coefficients that are often set as arbitrary parameters in generic Abelian models.Comment: 30 pages, 6 figure

    Relativistic effects and primordial non-Gaussianity in the galaxy bias

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    When dealing with observables, one needs to generalize the bias relation between the observed galaxy fluctuation field to the underlying matter distribution in a gauge-invariant way. We provide such relation at second-order in perturbation theory adopting the local Eulerian bias model and starting from the observationally motivated uniform-redshift gauge. Our computation includes the presence of primordial non-Gaussianity. We show that large scale-dependent relativistic effects in the Eulerian bias arise independently from the presence of some primordial non-Gaussianity. Furthermore, the Eulerian bias inherits from the primordial non-Gaussianity not only a scale-dependence, but also a modulation with the angle of observation when sources with different biases are correlated.Comment: 12 pages, LaTeX file; version accepted for publication in JCA

    Thermal production of relativistic Majorana neutrinos: Strong enhancement by multiple soft scattering

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    The production rate of heavy Majorana neutrinos is relevant for models of thermal leptogenesis in the early Universe. In the high temperature limit the production can proceed via the 1 2 (inverse) decays which are allowed by the thermal masses. We consider new production mechanisms which are obtained by including additional soft gauge interactions with the plasma. We show that an arbitrary number of such interactions gives leading order contributions, and we sum all of them. The rate turns out to be smooth in the region where the 1 2 processes are kinematically forbidden. At higher temperature it is enhanced by a factor 3 compared to the 1 2 rate.Comment: 26 pages, 8 figures; added references, added comments on 2 to 2 scattering processes, improved appearance of fig. 8, corrected typos; matches published versio

    Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

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    Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
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