Separation of a single photon and products of the π0,η,Ks0\pi^0,\eta, K^0_s meson neutral decay channels in the CMS electromagnetic calorimeter using neural network

The artificial neural network approach is used for separation of signals from a single photon $\gamma$ and products of the $\pi^0,\eta, K^0_s$ meson neutral decay channels on the basis of the data from the CMS electromagnetic calorimeter alone. Rejection values for the three types of mesons as a function of single photon selection efficiencies are obtained for two Barrel and one Endcap pseudorapidity regions and initial \Et of 20, 40, 60 and 100 GeV.Comment: 16 pages, uses cernrep.cls style fil

Energy and macronutrient intake and dietary pattern among school children in Bahrain: a cross-sectional study

Abstract Background Obesity is increasing in Bahrain and there is lack of information on the energy and macronutrient intake of children. The objective of this research was to study the energy and macronutrient intake as well as food frequency pattern of Bahraini school children. Methods This is a cross-sectional descriptive study conducted on Bahraini school boys and girls aged 6-18 years from all the 11 populated regions of the country. Data on food intake consisted of a 24-hour dietary recall and was obtained by interviewing a sub-sample of the study population. Information was also obtained through a self-administered questionnaire for the entire sample on the weekly frequency of food items that were grouped into 7 categories based on similarity of nutrient profiles. Dietary analysis was performed using the Nutritionist 5 (First Data Bank Version 1.6 1998). Results While the average energy intake of students was close to the Estimated Average Requirements of the UK Reference standards, protein intake substantially exceeded the Reference Nutrient Intake values as did daily sugar consumption. Dietary fiber fell short of the Dietary Recommended Values (UK) and 36%-50% students exceeded the Energy % limits for total fat, saturated fat and cholesterol. The Polyunsaturated: Saturated fat ratio remained at an unacceptable level of 0.6 for girls and boys. While sweets, snacks and regular soda drinks were popular, milk, fruits and vegetables were not commonly consumed. Conclusions High sugar consumption, low intake of dietary fiber and high energy % of saturated fat and dietary cholesterol by many Bahraini children, is likely to increase their risk of obesity and cardiovascular diseases in later life. Nutrition education programs in schools should emphasize the importance of healthy balanced diets for growth and health maintenance of children as well as dietary prevention of diseases.</p

Human rights, health and the state in Bangladesh

BACKGROUND: This paper broadly discusses the role of the State of Bangladesh in the context of the health system and human rights. The interrelation between human rights, health and development are well documented. The recognition of health as a fundamental right by WHO and subsequent approval of health as an instrument of welfare by the Universal Declaration of Human Rights (UDHR) and the International Covenant on Social, Economic and Cultural Rights (ICSECR) further enhances the idea. Moreover, human rights are also recognized as an expedient of human development. The state is entrusted to realize the rights enunciated in the ICSECR. DISCUSSION: In exploring the relationship of the human rights and health situation in Bangladesh, it is argued, in this paper, that the constitution and major policy documents of the Bangladesh government have recognized the health rights and development. Bangladesh has ratified most of the international treaties and covenants including ICCPR, ICESCR; and a signatory of international declarations including Alma-Ata, ICPD, Beijing declarations, and Millennium Development Goals. However the implementation of government policies and plans in the development of health institutions, human resources, accessibility and availability, resource distribution, rural-urban disparity, the male-female gap has put the health system in a dismal state. Neither the right to health nor the right to development has been established in the development of health system or in providing health care. SUMMARY: The development and service pattern of the health system have negative correlation with human rights and contributed to the underdevelopment of Bangladesh. The government should take comprehensive approach in prioritizing the health rights of the citizens and progressive realization of these rights

Study of the doubly charmed tetraquark T+cc

Quantum chromodynamics, the theory of the strong force, describes interactions of coloured quarks and gluons and the formation of hadronic matter. Conventional hadronic matter consists of baryons and mesons made of three quarks and quark-antiquark pairs, respectively. Particles with an alternative quark content are known as exotic states. Here a study is reported of an exotic narrow state in the D0D0π+ mass spectrum just below the D*+D0 mass threshold produced in proton-proton collisions collected with the LHCb detector at the Large Hadron Collider. The state is consistent with the ground isoscalar T+cc tetraquark with a quark content of ccu⎯⎯⎯d⎯⎯⎯ and spin-parity quantum numbers JP = 1+. Study of the DD mass spectra disfavours interpretation of the resonance as the isovector state. The decay structure via intermediate off-shell D*+ mesons is consistent with the observed D0π+ mass distribution. To analyse the mass of the resonance and its coupling to the D*D system, a dedicated model is developed under the assumption of an isoscalar axial-vector T+cc state decaying to the D*D channel. Using this model, resonance parameters including the pole position, scattering length, effective range and compositeness are determined to reveal important information about the nature of the T+cc state. In addition, an unexpected dependence of the production rate on track multiplicity is observed

BioNAR: An Integrated Biological Network Analysis Package in Bioconductor

Biological function in protein complexes emerges from more than just the sum of their parts: Molecules interact in a range of different subcomplexes and transfer signals/information around internal pathways. Modern proteomic techniques are excellent at producing a parts-list for such complexes, but more detailed analysis demands a network approach linking the molecules together and analyzing the emergent architectural properties. Methods developed for the analysis of networks in social sciences have proven very useful for splitting biological networks into communities leading to the discovery of sub-complexes enriched with molecules associated with specific diseases or molecular functions that are not apparent from the constituent components alone. Here we present the Bioconductor package BioNAR which supports step-by-step analysis of biological/biomedical networks with the aim of quantifying and ranking each of the network’s vertices based on network topology and clustering. Examples demonstrate that while BioNAR is not restricted to proteomic networks, it can predict a protein’s impact within multiple complexes, and enables estimation of the co-occurrence of meta-data, i.e., diseases and functions across the network, identifying the clusters whose components are likely to share common function and mechanisms. The package is available from Bioconductor release 3.16: https://bioconductor.org/packages/release/bioc/html/BioNAR.html The dataset is also related to the paper McLean et al. (in submission)

Synaptic Proteome SQLite database V1.00.1

Genes encoding synaptic proteins are highly associated with neuronal disorders many of which show clinical co-morbidity. Previously, we integrated 58 published synaptic proteomic datasets that describe over 8,000 proteins and combined them with direct protein-protein interactions and functional metadata to build a network resource that reveals the shared and unique protein components that underpin multiple disorders. All the data are provided in a flexible and accessible format to encourage custom use and available from here: https://datashare.ed.ac.uk/handle/10283/3877?show=full. In the current update we added 6 more synaptic proteome studies, which results in total of 64 studies. We introduced Synaptic Vesicle as a separate compartment. We also added coding mutations for Autistic Spectral disorder and Epilepsy collected from publicly available databases.Sorokina, Oksana; Armstromg, J Douglas. (2022). Synaptic Proteome SQLite database V1.00.1, 2000-2022 [software]. University of Edinburgh. School of Informatics. https://doi.org/10.7488/ds/3771