1,264 research outputs found
Gauge Orbit Types for Theories with Classical Compact Gauge Group
We determine the orbit types of the action of the group of local gauge
transformations on the space of connections in a principal bundle with
structure group O(n), SO(n) or over a closed, simply connected manifold
of dimension 4. Complemented with earlier results on U(n) and SU(n) this
completes the classification of the orbit types for all classical compact gauge
groups over such space-time manifolds. On the way we derive the classification
of principal bundles with structure group SO(n) over these manifolds and the
Howe subgroups of SO(n).Comment: 57 page
The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis.
The nuclear factor of activated T cells (NFAT) family of transcription factors controls calcium signaling in T lymphocytes. In this study, we have identified a crucial regulatory role of the transcription factor NFATc2 in T cell-dependent experimental colitis. Similar to ulcerative colitis in humans, the expression of NFATc2 was up-regulated in oxazolone-induced chronic intestinal inflammation. Furthermore, NFATc2 deficiency suppressed colitis induced by oxazolone administration. This finding was associated with enhanced T cell apoptosis in the lamina propria and strikingly reduced production of IL-6, -13, and -17 by mucosal T lymphocytes. Further studies using knockout mice showed that IL-6, rather than IL-23 and -17, are essential for oxazolone colitis induction. Administration of hyper-IL-6 blocked the protective effects of NFATc2 deficiency in experimental colitis, suggesting that IL-6 signal transduction plays a major pathogenic role in vivo. Finally, adoptive transfer of IL-6 and wild-type T cells demonstrated that oxazolone colitis is critically dependent on IL-6 production by T cells. Collectively, these results define a unique regulatory role for NFATc2 in colitis by controlling mucosal T cell activation in an IL-6-dependent manner. NFATc2 in T cells thus emerges as a potentially new therapeutic target for inflammatory bowel diseases
CCD BV and 2MASS photometric study of the open cluster NGC 1513
We present CCD BV and JHK 2MASS photometric data for the open cluster
NGC 1513. We observed 609 stars in the direction of the cluster up to a
limiting magnitude of mag. The star count method shows that the
centre of the cluster lies at ,
and its angular size is arcmin.
The optical and near-infrared two-colour diagrams reveal the colour excesses in
the direction of the cluster as , and
mag. These results are consistent with normal
interstellar extinction values. Optical and near-infrared Zero Age
Main-Sequences (ZAMS) provided an average distance modulus of
mag, which can be translated into a distance of
pc. Finally, using Padova isochrones we determined the metallicity
and age of the cluster as ( dex) and
, respectively.Comment: 15 pages, 12 figures and 4 tables, accepted for publication in
Astrophysics & Space Scienc
Ionization degree of the electron-hole plasma in semiconductor quantum wells
The degree of ionization of a nondegenerate two-dimensional electron-hole
plasma is calculated using the modified law of mass action, which takes into
account all bound and unbound states in a screened Coulomb potential.
Application of the variable phase method to this potential allows us to treat
scattering and bound states on the same footing. Inclusion of the scattering
states leads to a strong deviation from the standard law of mass action. A
qualitative difference between mid- and wide-gap semiconductors is
demonstrated. For wide-gap semiconductors at room temperature, when the bare
exciton binding energy is of the order of T, the equilibrium consists of an
almost equal mixture of correlated electron-hole pairs and uncorrelated free
carriers.Comment: 22 pages, 6 figure
Finite element simulation of three-dimensional free-surface flow problems
An adaptive finite element algorithm is described for the stable solution of three-dimensional free-surface-flow problems based primarily on the use of node movement. The algorithm also includes a discrete remeshing procedure which enhances its accuracy and robustness. The spatial discretisation allows an isoparametric piecewise-quadratic approximation of the domain geometry for accurate resolution of the curved free surface.
The technique is illustrated through an implementation for surface-tension-dominated viscous flows modelled in terms of the Stokes equations with suitable boundary conditions on the deforming free surface. Two three-dimensional test problems are used to demonstrate the performance of the method: a liquid bridge problem and the formation of a fluid droplet
Absolute Proper Motions to B~22.5: IV. Faint, Low Velocity White Dwarfs and the White Dwarf Population Density Law
The reduced proper motion diagram (RPMD) for a complete sample of faint stars
with high accuracy proper motions in the North Galactic Pole field SA57 is
investigated. Eight stars with very large reduced proper motions are identified
as faint white dwarf candidates. We discriminate these white dwarf candidates
from the several times more numerous QSOs based on proper motion and
variability.
We discuss the implausibility that these stars could be any kind of survey
contaminant. If {\it bona fide} white dwarfs, the eight candidates found here
represent a portion of the white dwarf population hitherto uninvestigated by
previous surveys by virtue of the faint magnitudes and low proper motions. The
newly discovered stars suggest a disk white dwarf scaleheight larger than the
values of 250-350 pc typically assumed in assessments of the local white dwarf
density. Both a <V/V_{max}> and a more complex maximum likelihood analysis of
the spatial distribution of our likely thin disk white dwarfs yield
scaleheights of 400-600 pc while at the same time give a reasonable match to
the local white dwarf volume density found in other surveys.
Our results could have interesting implications for white dwarfs as potential
MACHO objects. We can place some direct constraints (albeit weak ones) on the
contribution of halo white dwarfs to the dark matter of the Galaxy. Moreover,
the elevated scale height that we measure for the thin disk could alter the
interpretation of microlensing results to the extent of making white dwarfs
untenable as the dominant MACHO contributor. (Abridged)Comment: 38 pages, 5 figures, to appear in April Ap
Low Q^2 Jet Production at HERA and Virtual Photon Structure
The transition between photoproduction and deep-inelastic scattering is
investigated in jet production at the HERA ep collider, using data collected by
the H1 experiment. Measurements of the differential inclusive jet
cross-sections dsigep/dEt* and dsigmep/deta*, where Et* and eta* are the
transverse energy and the pseudorapidity of the jets in the virtual
photon-proton centre of mass frame, are presented for 0 < Q2 < 49 GeV2 and 0.3
< y < 0.6. The interpretation of the results in terms of the structure of the
virtual photon is discussed. The data are best described by QCD calculations
which include a partonic structure of the virtual photon that evolves with Q2.Comment: 20 pages, 5 Figure
A Model for the Development of the Rhizobial and Arbuscular Mycorrhizal Symbioses in Legumes and Its Use to Understand the Roles of Ethylene in the Establishment of these two Symbioses
We propose a model depicting the development of nodulation and arbuscular mycorrhizae. Both processes are dissected into many steps, using Pisum sativum L. nodulation mutants as a guideline. For nodulation, we distinguish two main developmental programs, one epidermal and one cortical. Whereas Nod factors alone affect the cortical program, bacteria are required to trigger the epidermal events. We propose that the two programs of the rhizobial symbiosis evolved separately and that, over time, they came to function together. The distinction between these two programs does not exist for arbuscular mycorrhizae development despite events occurring in both root tissues. Mutations that affect both symbioses are restricted to the epidermal program. We propose here sites of action and potential roles for ethylene during the formation of the two symbioses with a specific hypothesis for nodule organogenesis. Assuming the epidermis does not make ethylene, the microsymbionts probably first encounter a regulatory level of ethylene at the epidermis–outermost cortical cell layer interface. Depending on the hormone concentrations there, infection will either progress or be blocked. In the former case, ethylene affects the cortex cytoskeleton, allowing reorganization that facilitates infection; in the latter case, ethylene acts on several enzymes that interfere with infection thread growth, causing it to abort. Throughout this review, the difficulty of generalizing the roles of ethylene is emphasized and numerous examples are given to demonstrate the diversity that exists in plants
Energy Flow in the Hadronic Final State of Diffractive and Non-Diffractive Deep-Inelastic Scattering at HERA
An investigation of the hadronic final state in diffractive and
non--diffractive deep--inelastic electron--proton scattering at HERA is
presented, where diffractive data are selected experimentally by demanding a
large gap in pseudo --rapidity around the proton remnant direction. The
transverse energy flow in the hadronic final state is evaluated using a set of
estimators which quantify topological properties. Using available Monte Carlo
QCD calculations, it is demonstrated that the final state in diffractive DIS
exhibits the features expected if the interaction is interpreted as the
scattering of an electron off a current quark with associated effects of
perturbative QCD. A model in which deep--inelastic diffraction is taken to be
the exchange of a pomeron with partonic structure is found to reproduce the
measurements well. Models for deep--inelastic scattering, in which a
sizeable diffractive contribution is present because of non--perturbative
effects in the production of the hadronic final state, reproduce the general
tendencies of the data but in all give a worse description.Comment: 22 pages, latex, 6 Figures appended as uuencoded fil
A Search for Selectrons and Squarks at HERA
Data from electron-proton collisions at a center-of-mass energy of 300 GeV
are used for a search for selectrons and squarks within the framework of the
minimal supersymmetric model. The decays of selectrons and squarks into the
lightest supersymmetric particle lead to final states with an electron and
hadrons accompanied by large missing energy and transverse momentum. No signal
is found and new bounds on the existence of these particles are derived. At 95%
confidence level the excluded region extends to 65 GeV for selectron and squark
masses, and to 40 GeV for the mass of the lightest supersymmetric particle.Comment: 13 pages, latex, 6 Figure
- …