The MELD Programming Language: User Manual

This manual is divided into two parts, a tutorial introduction to the MELD programming language, and a language reference manual. The index spans both parts. A bibliography of MELD publications and technical reports is available in Appendix II. If you are interested in the decisions leading to the current design you should refer to this literature; the intent of this manual is to provide a working description of the current language and its implementation, and not an exposition of the language issues. Chapter 9 describes the language features which are not yet implemented

Web user interface design strategy: Designing for device independence

Until recently, Web services were available only through a desktop web browser. Nowadays, methods of access move beyond the desktop computer towards ubiquitous access through portable devices. As a consequence, users have the chance to interact with a growing diversity of computing devices such as PDAs, smart phones, etc., with diverse characteristics that tend to replace conventional laptop and desktop computers. User interface designers, on the other hand, strive to design usable interfaces to cater for the diverse requirements of these devices. The design strategy proposed in this paper aims at assisting user interface designers in designing for diverse devices recommending a specific line of activities in the process of design. A case study of application of the proposed design strategy is presented, outlining its advantages

Towards Activity Context using Software Sensors

Service-Oriented Computing delivers the promise of configuring and reconfiguring software systems to address user's needs in a dynamic way. Context-aware computing promises to capture the user's needs and hence the requirements they have on systems. The marriage of both can deliver ad-hoc software solutions relevant to the user in the most current fashion. However, here it is a key to gather information on the users' activity (that is what they are doing). Traditionally any context sensing was conducted with hardware sensors. However, software can also play the same role and in some situations will be more useful to sense the activity of the user. Furthermore they can make use of the fact that Service-oriented systems exchange information through standard protocols. In this paper we discuss our proposed approach to sense the activity of the user making use of software

Coupling of alpha(1)-Adrenoceptors to ERK1/2 in the Human Prostate

Introduction: alpha(1)-Adrenoceptors are considered critical for the regulation of prostatic smooth muscle tone. However, previous studies suggested further alpha(1)-adrenoceptor functions besides contraction. Here, we investigated whether alpha(1)-adrenoceptors in the human prostate may activate extracellular signal-regulated kinases (ERK1/2). Methods: Prostate tissues from patients undergoing radical prostatectomy were stimulated in vitro. Activation of ERK1/2 was assessed by Western blot analysis. Expression of ERK1/2 was studied by immunohistochemistry. The effect of ERK1/2 inhibition by U0126 on phenylephrine-induced contraction was studied in organ-bath experiments. Results: Stimulation of human prostate tissue with noradrenaline (30 mu M) or phenylephrine (10 mu M) resulted in ERK activation. This was reflected by increased levels of phosphorylated ERK1/2. Expression of ERK1/2 in the prostate was observed in smooth muscle cells. Incubation of prostate tissue with U0126 (30 mu M) resulted in ERK1/2 inhibition. Dose-dependent phenylephrine-induced contraction of prostate tissue was not modulated by U0126. Conclusions: alpha(1)-Adrenoceptors in the human prostate are coupled to ERK1/2. This may partially explain previous observations suggesting a role of alpha(1)-adrenoceptors in the regulation of prostate growth. Copyright (C) 2011 S. Karger AG, Base

Is Context-aware Reasoning = Case-based Reasoning?

The purpose of this paper is to explore the similarities and differences and then argue for the potential synergies between two methodologies, namely Context-aware Reasoning and Case-based Reasoning, that are amongst the tools which can be used for intelligent environment (IE) system development. Through a case study supported by a review of the literature, we argue that context awareness and case based reasoning are not equal and are complementary methodologies to solve a domain specific problem, rather, the IE development paradigm must build a cooperation between these two approaches to overcome the individual drawbacks and to maximise the success of the IE systems

Categorization of the context within the medical domain

The context itself has multiple meanings may vary according to the domain of application. This contextual flexibility was behind the emergence of so such huge number of context definitions. Nevertheless, all the proposed definitions do not provide solid ground for systems developers’ expectations, especially in healthcare domain [1]. This issue prompted researchers to divide the context into a set of concepts that would facilitate organizing of contextual knowledge. The conventional taxonomies of context are always too complex, and we need to fight to make them useful in the intended application area. In this paper, we propose a new context classification which covers almost all the context aspects that we may need to develop a tele-monitoring system for chronic disease management