130 research outputs found

    Ethnic disparities in quality of diabetes care in Scotland:a national cohort study

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    Aims: The aim of this study is to compare quality of diabetes care in people with type 2 diabetes by ethnicity, in Scotland. Methods: Using a linked national diabetes registry, we included 162,122 people newly diagnosed with type 2 diabetes between 2009 and 2018. We compared receipt of nine guideline indicated processes of care in the first-year post-diabetes diagnosis using logistic regression, comparing eight ethnicity groups to the White group. We compared annual receipt of HbA1c and eye screening during the entire follow-up using generalised linear mixed effects. All analyses adjusted for confounders. Results: Receipt of diabetes care was lower in other ethnic groups compared to White people in the first-year post-diagnosis. Differences were most pronounced for people in the: African, Caribbean or Black; Indian; and other ethnicity groups for almost all processes of care. For example, compared to White people, odds of HbA1c monitoring were: 44% lower in African, Caribbean or Black people (OR 0.56 [95% CI 0.48, 0.66]); 47% lower in Indian people (OR 0.53 [95% CI 0.47, 0.61]); and 50% lower in people in the other ethnicity group (OR 0.50 [95% CI 0.46, 0.58]). Odds of receipt of eye screening were 30%–40% lower in most ethnic groups compared to the White group. During median 5 year follow-up, differences in HbA1c monitoring and eye screening largely persisted, but attenuated slightly for the former. Conclusions: There are marked ethnic disparities in routine diabetes care in Scotland in the short- and medium-term following diabetes diagnosis. Further investigation is needed to establish and effectively address the underlying reasons.</p

    Characterization and Prevalence of a New Porcine Calicivirus in Swine, United States

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    Real-time reverse transcription PCR revealed that new St-Valerien–like porcine caliciviruses are prevalent (2.6%–80%; 23.8% overall) in finisher pigs in North Carolina. One strain, NC-WGP93C, shares 89.3%–89.7% genomic nucleotide identity with Canadian strains. Whether these viruses cause disease in pigs or humans or are of food safety concern requires further investigation

    Fundamental properties of Fanaroff-Riley II radio galaxies investigated via Monte Carlo simulations

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    [Abridged] Radio galaxies and quasars are among the largest and most powerful single objects known and are believed to have had a significant impact on the evolving Universe and its large scale structure. We explore the intrinsic and extrinsic properties of the population of FRII objects (kinetic luminosities, lifetimes, and the central densities of their environments). In particular, the radio and kinetic luminosity functions of FRIIs are investigated using the complete, flux limited radio catalogues of 3CRR and Best et al. We construct multidimensional Monte Carlo simulations using semi-analytical models of FRII radio source growth to create artificial samples of radio galaxies. Unlike previous studies, we compare radio luminosity functions found with both the observed and simulated data to explore the fundamental source parameters. We allow the source physical properties to co-evolve with redshift, and we find that all the investigated parameters most likely undergo cosmological evolution. Strikingly, we find that the break in the kinetic luminosity function must undergo redshift evolution of at least (1+z)^3. The fundamental parameters are strongly degenerate, and independent constraints are necessary to draw more precise conclusions. We use the estimated kinetic luminosity functions to set constraints on the duty cycles of these powerful radio sources. A comparison of the duty cycles of powerful FRIIs with those determined from radiative luminosities of AGN of comparable black hole mass suggests a transition in behaviour from high to low redshifts, corresponding to either a drop in the typical black hole mass of powerful FRIIs at low redshifts, or a transition to a kinetically-dominated, radiatively-inefficient FRII population.Comment: Accepted to MNRAS. 30 pages, 18 figures, 4 tables + online material (in appendix): 9 pages, 14 figure

    X-ray Emission from Optically Selected Radio-Intermediate and Radio-Loud Quasars

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    We present the results of an investigation into the X-ray properties of radio-intermediate and radio-loud quasars (RIQs and RLQs, respectively). We combine large, modern optical (e.g., SDSS) and radio (e.g., FIRST) surveys with archival X-ray data from Chandra, XMM-Newton, and ROSAT to generate an optically selected sample that includes 188 RIQs and 603 RLQs. This sample is constructed independently of X-ray properties but has a high X-ray detection rate (85%); it provides broad and dense coverage of the l-z plane, including at high redshifts (22% of objects have z=2-5), and it extends to high radio-loudness values (33% of objects have R*=3-5, using logarithmic units). We measure the "excess" X-ray luminosity of RIQs and RLQs relative to radio-quiet quasars (RQQs) as a function of radio loudness and luminosity, and parameterize the X-ray luminosity of RIQs and RLQs both as a function of optical/UV luminosity and also as a joint function of optical/UV and radio luminosity. RIQs are only modestly X-ray bright relative to RQQs; it is only at high values of radio-loudness (R*>3.5) and radio luminosity that RLQs become strongly X-ray bright. We find no evidence for evolution in the X-ray properties of RIQs and RLQs with redshift (implying jet-linked IC/CMB emission does not contribute substantially to the nuclear X-ray continuum). Finally, we consider a model in which the nuclear X-ray emission contains both disk/corona-linked and jet-linked components and demonstrate that the X-ray jet-linked emission is likely beamed but to a lesser degree than applies to the radio jet. This model is used to investigate the increasing dominance of jet-linked X-ray emission at low inclinations.Comment: Accepted to ApJ; 42 pages, 21 figures, 10 tables; version with full-res figures at http://www.astro.lsa.umich.edu/~mbrendan/rlqx.htm

    Chilean Education & A Radical Atmosphere of Change

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    Two Steroidal Alkaloids from a Sponge, Corticium Sp.

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