1,224 research outputs found
Freedmen with Firearms: White Terrorism and Black Disarmament During Reconstruction
The outcome of the Civil War brought freedom to over six million slaves of African descent. These Freedmen communities remained a critical source of labor for the agrarian based economy of the southern U.S. Conflicts erupted because former slaves sought to exercise their new freedoms against the restrictions placed on them by local authorities. New laws, mob actions and acts of organized white terrorism were used to subjugate free citizens and return them to their former stations of labor. Political activities and participation in the electoral process were violently discouraged. Vocal opponents of the new system were often targeted for murder along with their families. A vital component to this oppressive movement was a concerted effort among local southern governments to disarm African American citizens. Radical Republicans attempted to intercede with new laws based on 2nd amendment protections, but Northern indifference to the plight of former slaves made this politically futile. Unconstitutional firearm restrictions in the reconstruction south ensured that the subjugation of Freedmen would continue indefinitely. Without political agency, or the means of an organized community militia to generate such power, the realization of freedom and the rights of citizenship for African Americans remained unobtainable for nearly 100 years
Xylem surfactants introduce a new element to the cohesion-tension theory
Vascular plants transport water under negative pressure without constantly creating gas bubbles that would disable their hydraulic systems. Attempts to replicate this feat in artificial systems almost invariably result in bubble formation, except under highly controlled conditions with pure water and only hydrophilic surfaces present. In theory, conditions in the xylem should favor bubble nucleation even more: there are millions of conduits with at least some hydrophobic surfaces, and xylem sap is saturated or sometimes supersaturated with atmospheric gas and may contain surface-active molecules that can lower surface tension. So how do plants transport water under negative pressure? Here, we show that angiosperm xylem contains abundant hydrophobic surfaces as well as insoluble lipid surfactants, including phospholipids, and proteins, a composition similar to pulmonary surfactants. Lipid surfactants were found in xylem sap and as nanoparticles under transmission electron microscopy in pores of intervessel pit membranes and deposited on vessel wall surfaces. Nanoparticles observed in xylem sap via nanoparticle-tracking analysis included surfactant-coated nanobubbles when examined by freeze-fracture electron microscopy. Based on their fracture behavior, this technique is able to distinguish between dense-core particles, liquid-filled, bilayer-coated vesicles/liposomes, and gas-filled bubbles. Xylem surfactants showed strong surface activity that reduces surface tension to low values when concentrated as they are in pit membrane pores. We hypothesize that xylem surfactants support water transport under negative pressure as explained by the cohesion-tension theory by coating hydrophobic surfaces and nanobubbles, thereby keeping the latter below the critical size at which bubbles would expand to form embolisms
Constructing Self-Dual Strings
We present an ADHMN-like construction which generates self-dual string
solutions to the effective M5-brane worldvolume theory from solutions to the
Basu-Harvey equation. Our construction finds a natural interpretation in terms
of gerbes, which we develop in some detail. We also comment on a possible
extension to stacks of multiple M5-branes.Comment: 1+19 pages, presentation improved, minor corrections, published
versio
Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation
Objective Lysine acetylation is an important post-translational modification that regulates metabolic function in skeletal muscle. The acetyltransferase, general control of amino acid synthesis 5 (GCN5), has been proposed as a regulator of mitochondrial biogenesis via its inhibitory action on peroxisome proliferator activated receptor-γ coactivator-1α (PGC-1α). However, the specific contribution of GCN5 to skeletal muscle metabolism and mitochondrial adaptations to endurance exercise in vivo remain to be defined. We aimed to determine whether loss of GCN5 in skeletal muscle enhances mitochondrial density and function, and the adaptive response to endurance exercise training. Methods We used Cre-LoxP methodology to generate mice with muscle-specific knockout of GCN5 (mKO) and floxed, wildtype (WT) littermates. We measured whole-body energy expenditure, as well as markers of mitochondrial density, biogenesis, and function in skeletal muscle from sedentary mice, and mice that performed 20 days of voluntary endurance exercise training. Results Despite successful knockdown of GCN5 activity in skeletal muscle of mKO mice, whole-body energy expenditure as well as skeletal muscle mitochondrial abundance and maximal respiratory capacity were comparable between mKO and WT mice. Further, there were no genotype differences in endurance exercise-mediated mitochondrial biogenesis or increases in PGC-1α protein content. Conclusion These results demonstrate that loss of GCN5 in vivo does not promote metabolic remodeling in mouse skeletal muscle
D0-D4 brane tachyon condensation to a BPS state and its excitation spectrum in noncommutative super Yang-Mills theory
We investigate the D0-D4-brane system for different B-field backgrounds
including the small instanton singularity in noncommutative SYM theory. We
discuss the excitation spectrum of the unstable state as well as for the BPS
D0-D4 bound state. We compute the tachyon potential which reproduces the
complete mass defect. The relevant degrees of freedom are the massless (4,4)
strings. Both results are in contrast with existing string field theory
calculations. The excitation spectrum of the small instanton is found to be
equal to the excitation spectrum of the fluxon solution on R^2_theta x R which
we trace back to T-duality. For the effective theory of the (0,0) string
excitations we obtain a BFSS matrix model. The number of states in the
instanton background changes significantly when the B-field becomes self-dual.
This leads us to the proposal of the existence of a phase transition or cross
over at self-dual B-field.Comment: a4 11pt Latex2e 40 pages; v2: typos fixed, refined comments on
renormalisation, refs added, v3: ref added, version publishe
Mechanical adaptation of brachiopod shells via hydration-induced structural changes.
The function-optimized properties of biominerals arise from the hierarchical organization of primary building blocks. Alteration of properties in response to environmental stresses generally involves time-intensive processes of resorption and reprecipitation of mineral in the underlying organic scaffold. Here, we report that the load-bearing shells of the brachiopod Discinisca tenuis are an exception to this process. These shells can dynamically modulate their mechanical properties in response to a change in environment, switching from hard and stiff when dry to malleable when hydrated within minutes. Using ptychographic X-ray tomography, electron microscopy and spectroscopy, we describe their hierarchical structure and composition as a function of hydration to understand the structural motifs that generate this adaptability. Key is a complementary set of structural modifications, starting with the swelling of an organic matrix on the micron level via nanocrystal reorganization and ending in an intercalation process on the molecular level in response to hydration
Heterologous Array Analysis in Pinaceae: Hybridization of Pinus Taeda cDNA Arrays With cDNA From Needles and Embryogenic Cultures of P. Taeda, P. Sylvestris or Picea Abies
Hybridization of labelled cDNA from various cell types with high-density arrays of expressed sequence tags is a powerful technique for investigating gene expression. Few
conifer cDNA libraries have been sequenced. Because of the high level of sequence
conservation between Pinus and Picea we have investigated the use of arrays from
one genus for studies of gene expression in the other. The partial cDNAs from 384
identifiable genes expressed in differentiating xylem of Pinus taeda were printed on
nylon membranes in randomized replicates. These were hybridized with labelled
cDNA from needles or embryogenic cultures of Pinus taeda, P. sylvestris and Picea abies, and with labelled cDNA from leaves of Nicotiana tabacum. The Spearman
correlation of gene expression for pairs of conifer species was high for needles
(r2 = 0.78 − 0.86), and somewhat lower for embryogenic cultures (r2 = 0.68 − 0.83).
The correlation of gene expression for tobacco leaves and needles of each of the three
conifer species was lower but sufficiently high (r2 = 0.52 − 0.63) to suggest that many
partial gene sequences are conserved in angiosperms and gymnosperms. Heterologous
probing was further used to identify tissue-specific gene expression over species
boundaries. To evaluate the significance of differences in gene expression, conventional
parametric tests were compared with permutation tests after four methods of
normalization. Permutation tests after Z-normalization provide the highest degree
of discrimination but may enhance the probability of type I errors. It is concluded
that arrays of cDNA from loblolly pine are useful for studies of gene expression in
other pines or spruces
The Geology of the Marcia Quadrangle of Asteroid Vesta: Assessing the Effects of Large, Young Craters
We used Dawn spacecraft data to identify and delineate geological units and landforms in the Marcia quadrangle of Vesta as a means to assess the role of the large, relatively young impact craters Marcia (approximately 63 kilometers diameter) and Calpurnia (approximately 53 kilometers diameter) and their surrounding ejecta field on the local geology. We also investigated a local topographic high with a dark-rayed crater named Aricia Tholus, and the impact crater Octavia that is surrounded by a distinctive diffuse mantle. Crater counts and stratigraphic relations suggest that Marcia is the youngest large crater on Vesta, in which a putative impact melt on the crater floor ranges in age between approximately 40 and 60 million years (depending upon choice of chronology system), and Marcia's ejecta blanket ranges in age between approximately 120 and 390 million years (depending upon choice of chronology system). We interpret the geologic units in and around Marcia crater to mark a major Vestan time-stratigraphic event, and that the Marcia Formation is one of the geologically youngest formations on Vesta. Marcia crater reveals pristine bright and dark material in its walls and smooth and pitted terrains on its floor. The smooth unit we interpret as evidence of flow of impact melts and (for the pitted terrain) release of volatiles during or after the impact process. The distinctive dark ejecta surrounding craters Marcia and Calpurnia is enriched in OH- or H-bearing phases and has a variable morphology, suggestive of a complex mixture of impact ejecta and impact melts including dark materials possibly derived from carbonaceous chondrite-rich material. Aricia Tholus, which was originally interpreted as a putative Vestan volcanic edifice based on lower resolution observations, appears to be a fragment of an ancient impact basin rim topped by a dark-rayed impact crater. Octavia crater has a cratering model formation age of approximately 280-990 million years based on counts of its ejecta field (depending upon choice of chronology system), and its ejecta field is the second oldest unit in this quadrangle. The relatively young craters and their related ejecta materials in this quadrangle are in stark contrast to the surrounding heavily cratered units that are related to the billion years old or older Rheasilvia and Veneneia impact basins and Vesta's ancient crust preserved on Vestalia Terra
Structure and Evolution of the Lunar Procellarum Region as Revealed by GRAIL Gravity Data
The Procellarum region is a broad area on the nearside of the Moon that is characterized by low elevations, thin crust, and high surface concentrations of the heat-producing elements uranium, thorium, and potassium. The Procellarum region has been interpreted as an ancient impact basin approximately 3200 km in diameter, though supporting evidence at the surface would have been largely obscured as a result of the great antiquity and poor preservation of any diagnostic features. Here we use data from the Gravity Recovery and Interior Laboratory (GRAIL) mission to examine the subsurface structure of Procellarum. The Bouguer gravity anomalies and gravity gradients reveal a pattern of narrow linear anomalies that border the Procellarum region and are interpreted to be the frozen remnants of lava-filled rifts and the underlying feeder dikes that served as the magma plumbing system for much of the nearside mare volcanism. The discontinuous surface structures that were earlier interpreted as remnants of an impact basin rim are shown in GRAIL data to be a part of this continuous set of quasi-rectangular border structures with angular intersections, contrary to the expected circular or elliptical shape of an impact basin. The spatial pattern of magmatic-tectonic structures bounding Procellarum is consistent with their formation in response to thermal stresses produced by the differential cooling of the province relative to its surroundings, coupled with magmatic activity driven by the elevated heat flux in the region
- …