Effects of Ibuprofen intake in muscle damage, body temperature and muscle power in Paralympic powerlifting athletes

The aim of this study is to evaluate the effect of ingesting ibuprofen on post-workout recovery of muscle damage, body temperature and muscle power indicators in Paralympic powerlifting athletes. The study was carried out with eight Paralympic powerlifting athletes (aged 27.0 ± 5.3 years and 79.9 ± 25.5 kg of body mass) competing at the national level, with a minimum training experience of 12 months, who all submitted to two experimental conditions: Ibuprofen (2 × 00 mg) and control. The maximal isometric force of the upper limbs and rate of force development, thermography, and serum biochemical analyzes of creatine kinase, lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase were measured before, after, 24 h after and 48 h after the intervention. Maximal isometric force only decreased in the placebo condition, which increased back to baseline levels, while no substantial decline in baseline force was seen in the ibuprofen condition, although no effect for exercise condition was detected. After the exercise, the rate of force development decreased significantly for both conditions and did not exceed baseline levels again after 48 h. Muscle temperature decreased significantly at 48-h post-exercise in the placebo condition, when compared with the previous day of measurement; and deltoid muscle temperature at 48-h post-exercise was higher with the ibuprofen condition. Although the results indicate some positive effects of ibuprofen use, they do not enable a clear statement regarding its positive effects on muscle function and muscle damage. Ibuprofen seems to have caused a delay in the anti-inflammatory response following exercise.publishedVersio

Actividades corporales de aventura en la escuela: la carrera de orientación como propuesta en el desarrollo de habilidades socioemocionales

Os esportes de aventura quando tematizados nas aulas de Educação Física têm o potencial de despertar fortes emoções, principalmente pelas experiências de risco e aventura, no contexto escolar, a Base Nacional Comum Curricular-BNCC, existe há necessidade de se trabalhar a educação emocional. O objetivo deste estudo foi analisar o comportamento socioemocional dos alunos diante de uma intervenção de corrida de orientação. 39 escolares do ensino médio participaram do estudo. Foi aplicado o questionário Big Five Inventory (BFI) após uma intervenção de corrida de orientação para a avaliação do perfil socioemocional. Foi constado que as maiores médias entre os perfis foram: Abertura (34,59), amabilidade (30,44), conscienciosidade (28,23) (tabela 1). A corrida de orientação, se mostra eficaz no desempenho emocional dos escolares pois os perfis de maior as maiores medias foram para os perfis de: Abertura, amabilidade e conscienciosidade. Está intervenção também atende aos requisitos presentes no BNCC sobre o desenvolvimento emocional como também sobre a necessidade de práticas de aventura para a Educação Física.Adventure sports when thematized in Physical Education classes have the potential to arouse strong emotions, mainly through risk and adventure experiences, in the school context, the National Common Curricular Base-BNCC, there is a need to work on emotional education. The objective of this study was to analyze the socio-emotional behavior of students in the face of an orienteering race intervention. 39 high school students participated in the study. The Big Five Inventory (BFI) questionnaire was applied after an orienteering race intervention to assess the socio-emotional profile. It was found that the highest averages among the profiles were: Openness (34.59), kindness (30.44), conscientiousness (28.23) (Table 1). The orienteering race proves to be effective in the emotional performance of the students because the profiles of the highest the highest averages were for the profiles of: Openness, kindness and conscientiousness. This intervention also meets the requirements present in the BNCC on emotional development as well as on the need for adventure practices for Physical Education.Los deportes de aventura cuando son tematizados en las clases de Educación Física tienen el potencial de despertar emociones fuertes, principalmente a través de experiencias de riesgo y aventura, en el contexto escolar, Base Curricular Común NacionalBNCC, existe la necesidad de trabajar la educación emocional. El objetivo de este estudio fue analizar el comportamiento socioemocional de los estudiantes ante una intervención de carrera de orientación. 39 estudiantes de secundaria participaron en el estudio. Se aplicó el cuestionario Big Five Inventory (BFI) después de una intervención de carrera de orientación para evaluar el perfil socioemocional. Se encontró que los promedios más altos entre los perfiles fueron: Apertura (34,59), amabilidad (30,44), escrupulosidad (28,23) (Tabla 1). La carrera de orientación demuestra ser efectiva en el desempeño emocional de los estudiantes debido a que los perfiles de los más altos los promedios más altos fueron para los perfiles de: Apertura, amabilidad y escrupulosidad. Esta intervención también cumple con los requisitos presentes en el BNCC sobre el desarrollo emocional, así como sobre la necesidad de prácticas de aventura para la Educación Física.Facultad de Humanidades y Ciencias de la Educació

Effects of Ibuprofen Use on Lymphocyte Count and Oxidative Stress in Elite Paralympic Powerlifting.

Background: Paralympic Powerlifting (PP) training tends to promote fatigue and oxidative stress. Objective: To analyze the effects of ibuprofen use on performance and oxidative stress in post-training PP athletes. Methodology: Ten national level PP athletes (age: 27.13 ± 5.57) were analyzed for oxidative stress in post-training. The study was carried out in three weeks, (1) familiarization and (2 and 3) evaluated the recovery with the use of a placebo (PLA) and ibuprofen (IBU), 800 mg. The Peak Torque (PT), Torque Development Rate (TDR), Fatigue Index (FI), reactive substances to thiobarbituric acid (TBARS) and sulfhydryl groups (SH) were evaluated. The training consisted of five sets of five repetitions (80–90%) 1-Repetition Maximum (1-RM) in the bench press. Results: The IBU showed a higher PT (24 and 48 h, p = 0.04, ɳ2 p = 0.39), a lower FI (24 h, p = 0.01, ɳ2p = 0.74) and an increased lymphocyte count (p < 0.001; ɳ2p = 4.36). There was no change in oxidative stress. Conclusions: The use of IBU provided improvements in strength and did not protect against oxidative stresspost-print915 K

Cymbopogon winterianus essential oil attenuates bleomycin-induced pulmonary fibrosis in a murine model

The essential oil of Cymbopogon winterianus (EOCW) is a natural product with antioxidant, anti-inflammatory, and antifibrotic properties. We studied the effect of EOCW in the progression of histological changes of pulmonary fibrosis (PF) in a rodent model. The oil was obtained by hydrodistillation and characterized using gas chromatographymass spectrometry. Intratracheal instillation of bleomycin was performed in 30 rats to induce PF, while Sham animals were subjected to instillation of saline solution. The treatment was performed using daily oral administration of distilled water, EOCW at 50, 100, and 200 mg/kg, and deflazacort (DFC). After 28 days, hemogram and bronchoalveolar lavage fluid (BALF), tissue levels of malondialdehyde (MDA), superoxide dismutase (SOD), and catalase (CAT) were assayed. Histological grading of PF, immunohistochemical expression of -smooth muscle actin (-SMA), and transforming growth factor- (TGF-) were also analyzed. The EOCW major compounds were found to be citronellal, geraniol, and citronellol. EOCW significantly reduced inflammation in BALF, reduced MDA levels, and increased SOD activity. EOCW attenuated histological grading of PF and reduced immunohistochemical expression of -SMA and TGF- in a dose-dependent way, likely due to the reduction of oxidative stress, inflammation, and TGF--induced myofibroblast differentiation.This research was financed by the Coordenação Aperfeiçoamento de Pessoal de Nivel Superior (CAPES), Fundação de Amparo à Pesquisa do Estado de Sergipe (FAPITEC), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). EBS wishes to acknowledge the sponsorship of the project UIDB/04469/2020 (strategic fund) from the Portuguese Science and Technology Foundation, Ministry of Science and Education (FCT/MEC) through national funds, and was co-financed by FEDER, under the Partnership Agreement PT2020.info:eu-repo/semantics/publishedVersio

Effects of Resistance Training on Oxidative Stress Markers and Muscle Damage in Spinal Cord Injured Rats

Background: Spinal cord injury (SCI) is a condition that affects the central nervous system, is characterized by motor and sensory impairments, and impacts individuals’ lives. The objective of this study was to evaluate the effects of resistance training on oxidative stress and muscle damage in spinal cord injured rats. Methodology: Forty Wistar rats were selected and divided equally into five groups: Healthy Control (CON), Sham (SHAM) SCI Untrained group (SCI-U), SCI Trained group (SCI- T), SCI Active Trained group (SCI- AT). Animals in the trained groups were submitted to an incomplete SCI at T9. Thereafter, they performed a protocol of resistance training for four weeks. Results: Significant differences in muscle damage markers and oxidative stress in the trained groups, mainly in SCI- AT, were found. On the other hand, SCI- U group presented higher levels of oxidative stress and biomarkers of LDH and AST. Conclusion: The results highlight that resistance training promoted a decrease in oxidative stress and a significative response in muscle damage markers. Keywords: spinal cord injury; resistance training; oxidative stress; muscle damag

Effects of 16 weeks of a physical exercise program on blood markers, functional autonomy and level of depression in elderly and old adults.

O objetivo foi analisar os efeitos de um programa de exerc?cio f?sico sobre marcadores sangu?neos, autonomia funcional e n?vel de depress?o. Um total de 112 sujeitos com doen?as metab?licas controladas por hipocolesterolemia e hipoglicemiantes distribu?dos em dois grupos participaram do estudo; grupo composto por 54 membros com idade m?dia de 62,11 anos e grupo controle (GC) com 58 indiv?duos com idade m?dia de 63,03 anos. Foi observado que a ur?ia, creatina e as vari?veis pot?ssio n?o apresentaram diferen?a interessante entre os dois momentos do estudo, enquanto TGP e s?dio obtiveram redu??es nos valores m?dios de 2,46 mg / dl e 10 mg / dl com grande efeito de ?p2 0,153, ?p2 0,43 e signific?ncia p <0,047 e p <0,039 ao comparar os dois momentos entre os grupos exerc?cio / controle. A qualidade da for?a entre os momentos pr? e p?s entre os grupos exerc?cio / controle mostrou um aumento de 2,53 kgf de pequeno efeito de ?p2,23 para o grupo exerc?cio, enquanto o controle reduziu. Tamb?m houve diferen?as entre o pr? e o p?s-treinamento nos indicadores de autonomia funcional dos grupos GC. O GE reduziu os n?veis de depress?o em rela??o ao GC. Concluiu-se que o treinamento f?sico realizado por 16 semanas foi eficaz na redu??o dos n?veis de s?dio, a vari?vel TGP, aumento dos n?veis de for?a dos membros superiores, al?m de favorecer a melhora da capacidade funcional e reduzir os n?veis de depress?o.The objective was to analyze the effects of a physical exercise program on blood markers, functional autonomy and level of depression. A total of 112 subjects with metabolic diseases controlled by hypocholesterolemia and hypoglycemics distributed in two groups participated in the study; group composed of 54 members with mean age of 62.11 years and control group (CG) with 58 individuals with a mean age of 63.03 years. It was observed that urea, creatine and potassium variables did not present an interesting difference between the two moments of the study, while TGP and sodium obtained reductions in mean values of 2.46 mg / dl and 10 mg / dl with a great effect of ?p2 0.153, ?p2 0.43 and significance p <0.047 and p <0.039 when comparing the two moments between the exercise / control groups. The quality of the force between the pre and post moments between the exercise / control groups showed an increase of 2.53 kgf of small effect of ?p2,23 for the exercise group, while the control reduced. There were also differences between pre and post-training in the functional autonomy indicators of the CG groups. The GE reduced the levels of depression compared to the CG. It was concluded that physical training performed for 16 weeks was effective in reducing sodium levels, the TGP variable, increased strength levels of the upper limbs, as well as improving functional capacity and reducing depression levels

Effects of Ibuprofen intake in muscle damage, body temperature and muscle power in Paralympic powerlifting athletes

The aim of this study is to evaluate the effect of ingesting ibuprofen on post-workout recovery of muscle damage, body temperature and muscle power indicators in Paralympic powerlifting athletes. The study was carried out with eight Paralympic powerlifting athletes (aged 27.0 ± 5.3 years and 79.9 ± 25.5 kg of body mass) competing at the national level, with a minimum training experience of 12 months, who all submitted to two experimental conditions: Ibuprofen (2 × 00 mg) and control. The maximal isometric force of the upper limbs and rate of force development, thermography, and serum biochemical analyzes of creatine kinase, lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase were measured before, after, 24 h after and 48 h after the intervention. Maximal isometric force only decreased in the placebo condition, which increased back to baseline levels, while no substantial decline in baseline force was seen in the ibuprofen condition, although no effect for exercise condition was detected. After the exercise, the rate of force development decreased significantly for both conditions and did not exceed baseline levels again after 48 h. Muscle temperature decreased significantly at 48-h post-exercise in the placebo condition, when compared with the previous day of measurement; and deltoid muscle temperature at 48-h post-exercise was higher with the ibuprofen condition. Although the results indicate some positive effects of ibuprofen use, they do not enable a clear statement regarding its positive effects on muscle function and muscle damage. Ibuprofen seems to have caused a delay in the anti-inflammatory response following exercise

Blood glucose and sleep quality in elderly participants of a physical exercise program : pilot study.

O envelhecimento populacional no mundo tem sido elevado nos pa?ses em desenvolvimento nas ?ltimas d?cadas. O Brasil est? entre os pa?ses que contribuir?o para essa proje??o, com um aumento significativo at? 2030. O objetivo foi analisar os efeitos de um programa de exerc?cio f?sico sobre marcadores sangu?neos e qualidade do sono em idosos. Um total de 118 idosos com doen?as metab?licas controladas por medica??es hipocolesterol?micas e hipoglicemiantes participaram do estudo. Os participantes foram divididos em dois grupos, um grupo exerc?cio (GE) composto por 58 indiv?duos com idade m?dia de 62 anos e grupo controle (GC) de 60 indiv?duos com m?dia de idade de 63 anos. Os n?veis de glicose no sangue mostraram uma redu??o m?dia de cerca de 23 mg / dl. O escore do PSQI mostrou uma redu??o significativa de cerca de 3 pontos (p <0,001, ?p2 = 0,78) na compara??o do GE com o GC. Pode-se concluir que o programa combinado de exerc?cio f?sico, realizado por 12 semanas, com frequ?ncia de tr?s vezes por semana, durante 60 min, foi eficaz na melhora da qualidade do sono dos idosos. Palavras-chave: Exerc?cio F?sico, Elderly, Glicose, Qualidade do Sono.Population aging in the world has been high in developing countries in the last decades. Brazil is among those countries that will contribute to this projection, with a significant increase until 2030. The objective was to analyze the effects of a physical exercise program on blood markers and sleep quality in the elderly. A total of 118 elderly people with metabolic diseases controlled by hypocholesterolemic and hypoglycemic medications participated in the study. The participants were divided into two groups, an exercise group (EG) composed of 58 individuals with a mean age of 62 years and control group (CG) of 60 individuals with a mean age of 63 years. Blood glucose levels showed a mean reduction of about 23 mg/dl. The PSQI score showed a significant reduction of about 3 points (p < 0.001, ?p2=0.78) on comparing the EG with the CG. It can be concluded that the physical exercise combined program performed for 12 weeks at a frequency of three times a week for 60 min, was effective in improving the sleep quality of the elderly. Keywords: Physical Exercise, Elderly, Glucose, Sleep Quality

Does Croton argyrophyllus extract has an effect on muscle damage and lipid peroxidation in rats submitted to high intensity strength exercise?

Many species of the genus Croton have been used for anti-inflammatory, antiproliferative, antidiabetic, and antitumor purposes. The objective was to evaluate the e ect of a hydroethanolic extract (HEE) from the inner bark of Croton argyrophyllus (Euphorbiaceae) on muscle damage and oxidative stress in rats after high intensity exercise. The animals were divided into four groups: (i) the sedentary group (SV; n = 7), (ii) the exercise vehicle group (EV, n = 7), (iii) the sedentary group HEE (SHG; n = 7) composed of sedentary animals and treated with the hydroethanolic extract of C. argyrophyllus (200 mg/kg, v.o.), and (iv) the HEE exercise group (HEE; n = 7) composed of animals submitted to resistance exercise (RE) and treated with the hydroethanolic extract of C. argyrophyllus (200 mg/kg, v.o.). In the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) test, the HEE showed lower values of inhibition potential (IP%) at 39.79% compared to gallic acid, 87.61%, and lipoperoxidation inhibition at 27.4% (100 ?g/mL) or 28.6% (200 ?g/mL) (p < 0.001). There was inhibition in free radicals in vivo. The HEE of C. argyrophyllus partially reduced the biomarkers of oxidative stress in muscle tissue and muscular damage (creatine kinase (CK) and Lactate Dehydrogenase (LDH)) (p < 0.05) in rats, and in this sense it can be an aid to the recovery process after exhaustive e orts