La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia desde departamentos de Bolívar, Sucre, Magdalena y Sainth Lamber (Canadá)

En el presente texto se pretende desde una mirada social analizar diferentes contextos de violencia en Colombia como es el relato de Shimaya, se refleja la realidad violenta que han sufrido las comunidades indígenas y campesinas en Colombia. El conflicto armado ha provocado desplazamientos, masacres y violaciones a los derechos humanos, dejando traumas individuales y sociales en las víctimas. Sin embargo, a pesar de los sucesos negativos, estas comunidades han demostrado resiliencia y empoderamiento al unirse para reconstruir sus comunidades, preservando su cultura y tradiciones. Es importante recordar que las experiencias traumáticas pueden transformarse en un proceso de crecimiento y desarrollo social con el apoyo adecuado. También se analizará una historia triste como lo fue “La masacre del Salado, en los Montes de Maria” en el año 2000, en donde los sobrevivientes continúan sufriendo los efectos de los traumas psicológicos. La violencia resultó en la destrucción de los lazos sociales y la identidad cultural de esta comunidad, que desde entonces ha estado tratando de reconstruirse. A pesar de la ausencia de protección estatal durante la tragedia, los sobrevivientes han mostrado resiliencia y fortaleza. A través de las narrativas del trauma y las acciones psicosociales, han encontrado formas de procesar sus experiencias y encontrar nuevas metas significativas que les permitan abandonar la violencia como instrumento de persuasión social. Esto ha resultado en un legado de resiliencia y fuerza propositiva para las generaciones futuras, así esta fuerza y resiliencia de cada uno de los sobrevivientes ofrecen esperanza para el futuro en Colombia.In this text it is intended from a social perspective to analyze different contexts of violence in Colombia such as Shimaya's story, reflecting the violent reality that indigenous and peasant communities have suffered in Colombia. The armed conflict has caused displacements, massacres, and human rights violations, leaving individual and social traumas in the victims. However, despite the negative events, these communities have shown resilience and empowerment by coming together to rebuild their communities, preserving their culture and traditions. It is important to remember that traumatic experiences can be transformed into a process of growth and social development with the right support. A sad story will also be analyzed as it was "The massacre of El Salado, in the Montes de Maria" in the year 2000. In which the survivors continue to suffer the effects of psychological trauma. The violence resulted in the destruction of the social ties and cultural identity of this community, which has been trying to rebuild itself ever since. Despite the absence of state protection during the tragedy, the survivors have shown resilience and strength. Through trauma narratives and psychosocial actions, they have found ways to process their experiences and find meaningful new goals that allow them to abandon violence as an instrument of social persuasion. This has resulted in a legacy of resilience and purposeful power for future generations. Thus, this strength and the resilience of the survivors offer hope for the social future in Colombia

Implementar un plan de mejora para el proceso de reclutamiento y selección del banco de Bogotá sede Megacity, Zipaquirá, para el segundo semestre del 2020

En este proyecto se centra en el estudio del proceso de reclutamiento y selección del banco de Bogotá sede Megacity, Zipaquirá, para el segundo semestre del 2020, en el cual se realiza una investigación basada en el método cualitativo. Como estrategia se realizarán encuestas a los miembros de la compañía, en la cual se requiere la elaboración de preguntas y cuestionarios en donde se identifiquen los puntos positivos, pero sobre todo las falencias que se están presentando. Se evidencia en los resultados de la encuesta el proceso de reclutamiento y selección de personal que implementa el banco cumple con un porcentaje bajo de satisfacción para sus empleados, es por esto que se debe implementar un plan de mejora del proceso. El área de recursos es un área fuerte en la compañía ya que esta permite cumplir las expectativas de todo personal que la conforma.This project focuses on the study of the recruitment and selection process of the Bogotá bank Megacity headquarters, Zipaquirá, for the second semester of 2020, in which an investigation based on the qualitative method is carried out. As a strategy, surveys will be conducted with the members of the company, which requires the preparation of questions and questionnaires where the positive points are identified, but especially the shortcomings that are being presented. The results of the survey show that the recruitment and selection process of personnel implemented by the bank meets a low percentage of satisfaction for its employees, which is why a process improvement plan must be implemented. The area of resources is a strong area in the company since it allows it to meet the expectations of all personnel that make it up

Selecting a BRCA risk assessment model for use in a familial cancer clinic

<p>Abstract</p> <p>Background</p> <p>Risk models are used to calculate the likelihood of carrying a <it>BRCA1 </it>or <it>BRCA2 </it>mutation. We evaluated the performances of currently-used risk models among patients from a large familial program using the criteria of high sensitivity, simple data collection and entry and <it>BRCA </it>score reporting.</p> <p>Methods</p> <p>Risk calculations were performed by applying the BRCAPRO, Manchester, Penn II, Myriad II, FHAT, IBIS and BOADICEA models to 200 non-<it>BRCA </it>carriers and 100 <it>BRCA </it>carriers, consecutively tested between August 1995 and March 2006. Areas under the receiver operating characteristic curves (AUCs) were determined and sensitivity and specificity were calculated at the conventional testing thresholds. In addition, subset analyses were performed for low and high risk probands.</p> <p>Results</p> <p>The BRCAPRO, Penn II, Myriad II, FHAT and BOADICEA models all have similar AUCs of approximately 0.75 for <it>BRCA </it>status. The Manchester and IBIS models have lower AUCs (0. and 0.47 respectively). At the conventional testing thresholds, the sensitivities and specificities for a <it>BRCA </it>mutation were, respectively, as follows: BRCAPRO (0.75, 0.62), Manchester (0.58,0.71), Penn II (0.93,0.31), Myriad II (0.71,0.63), FHAT (0.70,0.63), IBIS (0.20,0.74), BOADICEA (0.70, 0.65).</p> <p>Conclusion</p> <p>The Penn II model most closely met the criteria we established and this supports the use of this model for identifying individuals appropriate for genetic testing at our facility. These data are applicable to other familial clinics provided that variations in sample populations are taken into consideration.</p

A framework for human microbiome research

A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomic data available to the scientific community. Here we present resources from a population of 242 healthy adults sampled at 15 or 18 body sites up to three times, which have generated 5,177 microbial taxonomic profiles from 16S ribosomal RNA genes and over 3.5 terabases of metagenomic sequence so far. In parallel, approximately 800 reference strains isolated from the human body have been sequenced. Collectively, these data represent the largest resource describing the abundance and variety of the human microbiome, while providing a framework for current and future studies

Structure, function and diversity of the healthy human microbiome

Author Posting. © The Authors, 2012. This article is posted here by permission of Nature Publishing Group. The definitive version was published in Nature 486 (2012): 207-214, doi:10.1038/nature11234.Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin and vagina. Much of this diversity remains unexplained, although diet, environment, host genetics and early microbial exposure have all been implicated. Accordingly, to characterize the ecology of human-associated microbial communities, the Human Microbiome Project has analysed the largest cohort and set of distinct, clinically relevant body habitats so far. We found the diversity and abundance of each habitat’s signature microbes to vary widely even among healthy subjects, with strong niche specialization both within and among individuals. The project encountered an estimated 81–99% of the genera, enzyme families and community configurations occupied by the healthy Western microbiome. Metagenomic carriage of metabolic pathways was stable among individuals despite variation in community structure, and ethnic/racial background proved to be one of the strongest associations of both pathways and microbes with clinical metadata. These results thus delineate the range of structural and functional configurations normal in the microbial communities of a healthy population, enabling future characterization of the epidemiology, ecology and translational applications of the human microbiome.This research was supported in part by National Institutes of Health grants U54HG004969 to B.W.B.; U54HG003273 to R.A.G.; U54HG004973 to R.A.G., S.K.H. and J.F.P.; U54HG003067 to E.S.Lander; U54AI084844 to K.E.N.; N01AI30071 to R.L.Strausberg; U54HG004968 to G.M.W.; U01HG004866 to O.R.W.; U54HG003079 to R.K.W.; R01HG005969 to C.H.; R01HG004872 to R.K.; R01HG004885 to M.P.; R01HG005975 to P.D.S.; R01HG004908 to Y.Y.; R01HG004900 to M.K.Cho and P. Sankar; R01HG005171 to D.E.H.; R01HG004853 to A.L.M.; R01HG004856 to R.R.; R01HG004877 to R.R.S. and R.F.; R01HG005172 to P. Spicer.; R01HG004857 to M.P.; R01HG004906 to T.M.S.; R21HG005811 to E.A.V.; M.J.B. was supported by UH2AR057506; G.A.B. was supported by UH2AI083263 and UH3AI083263 (G.A.B., C. N. Cornelissen, L. K. Eaves and J. F. Strauss); S.M.H. was supported by UH3DK083993 (V. B. Young, E. B. Chang, F. Meyer, T. M. S., M. L. Sogin, J. M. Tiedje); K.P.R. was supported by UH2DK083990 (J. V.); J.A.S. and H.H.K. were supported by UH2AR057504 and UH3AR057504 (J.A.S.); DP2OD001500 to K.M.A.; N01HG62088 to the Coriell Institute for Medical Research; U01DE016937 to F.E.D.; S.K.H. was supported by RC1DE0202098 and R01DE021574 (S.K.H. and H. Li); J.I. was supported by R21CA139193 (J.I. and D. S. Michaud); K.P.L. was supported by P30DE020751 (D. J. Smith); Army Research Office grant W911NF-11-1-0473 to C.H.; National Science Foundation grants NSF DBI-1053486 to C.H. and NSF IIS-0812111 to M.P.; The Office of Science of the US Department of Energy under Contract No. DE-AC02-05CH11231 for P.S. C.; LANL Laboratory-Directed Research and Development grant 20100034DR and the US Defense Threat Reduction Agency grants B104153I and B084531I to P.S.C.; Research Foundation - Flanders (FWO) grant to K.F. and J.Raes; R.K. is an HHMI Early Career Scientist; Gordon&BettyMoore Foundation funding and institutional funding fromthe J. David Gladstone Institutes to K.S.P.; A.M.S. was supported by fellowships provided by the Rackham Graduate School and the NIH Molecular Mechanisms in Microbial Pathogenesis Training Grant T32AI007528; a Crohn’s and Colitis Foundation of Canada Grant in Aid of Research to E.A.V.; 2010 IBM Faculty Award to K.C.W.; analysis of the HMPdata was performed using National Energy Research Scientific Computing resources, the BluBioU Computational Resource at Rice University

Adams County Municipal Wastes Transfer Station

The current landfill located in Adams County, Idaho is nearing capacity due to uncontrolled and unregulated dumping. Adams Family, Inc. has been tasked with designing a new regional municipal wastes transfer station to help alleviate the problem and prolong the landfill’s useful life by preventing unregulated dumping and whereby reducing the wastes volume placed within the existing Adams County landfill. The new municipal wastes transfer station will be built on five acres of undeveloped land due north of the existing landfill entrance. The transfer station will be used to store recyclable municipal waste which will include scrap metal, used tires, electronic waste, batteries, green waste, and oil, before being transferred to a processing facility. The transfer station design includes: two storage sheds, two forty cubic yard roll-off containers, and designated areas to temporarily store municipal wastes from the general public and prevent every person from having unregulated access to the working landfill space. The municipal wastes transfer station design plans also include an office building complete with restrooms and a breakroom for a small number of landfill workers, a maintenance bay used for upkeep of onsite vehicles, and a wash station area for maintenance vehicles. A management plan is included to mitigate offsite stormwater from entering the landfill site and becoming contaminated. Pavement improvements will be made to the site and at the entrance to and from the landfill at Goodrich Road

Selecting a BRCA risk assessment model for use in a familial cancer clinic

Abstract Background Risk models are used to calculate the likelihood of carrying a BRCA1 or BRCA2 mutation. We evaluated the performances of currently-used risk models among patients from a large familial program using the criteria of high sensitivity, simple data collection and entry and BRCA score reporting. Methods Risk calculations were performed by applying the BRCAPRO, Manchester, Penn II, Myriad II, FHAT, IBIS and BOADICEA models to 200 non-BRCA carriers and 100 BRCA carriers, consecutively tested between August 1995 and March 2006. Areas under the receiver operating characteristic curves (AUCs) were determined and sensitivity and specificity were calculated at the conventional testing thresholds. In addition, subset analyses were performed for low and high risk probands. Results The BRCAPRO, Penn II, Myriad II, FHAT and BOADICEA models all have similar AUCs of approximately 0.75 for BRCA status. The Manchester and IBIS models have lower AUCs (0. and 0.47 respectively). At the conventional testing thresholds, the sensitivities and specificities for a BRCA mutation were, respectively, as follows: BRCAPRO (0.75, 0.62), Manchester (0.58,0.71), Penn II (0.93,0.31), Myriad II (0.71,0.63), FHAT (0.70,0.63), IBIS (0.20,0.74), BOADICEA (0.70, 0.65). Conclusion The Penn II model most closely met the criteria we established and this supports the use of this model for identifying individuals appropriate for genetic testing at our facility. These data are applicable to other familial clinics provided that variations in sample populations are taken into consideration

Impact of TIEG1 on the structural properties of fast- and slow-twitch skeletal muscle

International audienceIntroductionTransforming growth factor-beta (TGF-β)–inducible early gene-1 (TIEG1) is a transcription factor that is highly expressed in skeletal muscle. The purpose of this study was to characterize the structural properties of both fast-twitch (EDL) and slow-twitch (soleus) muscles in the hindlimb of TIEG1-deficient (TIEG1−/−) mice.MethodsTen slow and 10 fast muscles were analyzed from TIEG1−/− and wild-type (WT) mice using MRI texture (MRI-TA) and histological analyses.ResultsMRI-TA could discriminate between WT slow and fast muscles. Deletion of the TIEG1 gene led to changes in the texture profile within both muscle types. Specifically, muscle isolated from TIEG1−/− mice displayed hypertrophy, hyperplasia, and a modification of fiber area distribution.ConclusionsWe demonstrated that TIEG1 plays an important role in the structural properties of skeletal muscle. This study further implicates important roles for TIEG1 in the development of skeletal muscle and suggests that defects in TIEG1 expression and/or function may be associated with muscle disease

Molecular features of influenza A (H1N1)pdm09 prevalent in Mexico during winter seasons 2012-2014

<div><p>Since the emergence of the pandemic H1N1pdm09 virus in Mexico and California, biannual increases in the number of cases have been detected in Mexico. As observed in previous seasons, pandemic A/H1N1 09 virus was detected in severe cases during the 2011–2012 winter season and finally, during the 2013–2014 winter season it became the most prevalent influenza virus. Molecular and phylogenetic analyses of the whole viral genome are necessary to determine the antigenic and pathogenic characteristics of influenza viruses that cause severe outcomes of the disease. In this paper, we analyzed the evolution, antigenic and genetic drift of Mexican isolates from 2009, at the beginning of the pandemic, to 2014. We found a clear variation of the virus in Mexico from the 2011–2014 season due to different markers and in accordance with previous reports. In this study, we identified 13 novel substitutions with important biological effects, including virulence, T cell epitope presented by MHC and host specificity shift and some others substitutions might have more than one biological function. The systematic monitoring of mutations on whole genome of influenza A pH1N1 (2009) virus circulating at INER in Mexico City might provide valuable information to predict the emergence of new pathogenic influenza virus</p></div