247 research outputs found
Quais as Perspectivas da Produção de Biodiesel de Mamona no Nordeste Brasileiro?
O objetivo desse artigo é analisar as condições necessárias para o desenvolvimento do PNPB (Programa Nacional de Produção e Uso do Biodiesel) no nordeste brasileiro. A metodologia utilizada é essencialmente prospectiva, considerando o custo de oportunidade da produção de mamona para os agricultores familiares para avaliar como se comportam diante de variações de preço e produtividade da mamona, apontada como insumo mais adequado para o Biodiesel da região. Os resultados encontrados apontam para a necessidade de incrementos no nível de produtividade da cultura a fim de incentivar maior participação da agricultura tradicional. Há indícios de que uma média de produção próxima de 1ton/ha tornaria o plantio dessa oleaginosa viável para maior parte desses agricultores, contudo um acréscimo um pouco maior se faz necessário para tornar o biodiesel de mamona mais competitivo frente ao derivado de óleo de soja, assinalado como o mais apropriado para atender o programa no âmbito nacional.-----------The aim of this article is to analyze the necessary conditions for the development of the Programa Nacional de Produção e Uso de Biodiesel - PNPB in Brazilian Northeast. The methodology consider the opportunity cost of castor beans production for family farmers to assess how they react to variations in price and productivity of castor beans, identified as the most appropriate input to biodiesel in this region. Results show the need for increases in productivity in order to encourage greater participation of traditional farmers in the semi-arid. There is evidence that an average production close to one ton/ha turn production of castor beans viable for most of these farmers, however a higher increased is necessary to make biodiesel from castor beans competitive in relation to biodiesel obtained from soybeans, pointed as the most appropriate to meet the program at the national level.Mamona, Biodiesel, Produtividade, Agricultura familiar, viabilidade econômica, Castor beans, Biodiesel, Yield, Family agriculture, economic viability, Crop Production/Industries, Resource /Energy Economics and Policy,
PROVA AUTOMATIZADA DE TEOREMA EM LÓGICA PROPOSICIONAL
Este trabalho aborda o desenvolvimento de um sistema para prova automatizada de teoremas em lógica proposicional. O artigo apresenta os fundamentos teóricos gerais, questões operacionais e a estrutura de um software de prova de teoremas, elaborado com propósitos acadêmicos e didáticos, utilizando métodos de prova baseados em três tipos de tableaux semânticos: tableau de Smullyan, tableau com Lema e tableau KE. Experimentos foram realizados para verificar a correção dos resultados das provas, utilizando fórmulas geradas automaticamente.AbstractThis work describes the development of an automated theorem proving system of propositional logic. The paper presents the theoretical foundations, operational issues and structure of a theorem proving software, developed with academic and didactic purposes, using proof methods based on three semantics tableaux: Smullyan tableau, Lema tableau e KE tableau. Experiments were performed to verify the correctness of the results of the proofs, using automatically generating formulas
Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells
Acute myeloid leukaemia (AML) comprises a heterogeneous group of hematologic neoplasms characterized by diverse combinations of genetic, phenotypic and clinical features representing a major challenge for the development of targeted therapies. Metabolic reprogramming, mainly driven by deregulation of the nutrient-sensing pathways as AMPK, mTOR and PI3K/AKT, has been associated with cancer cells, including AML cells, survival and proliferation. Nevertheless, the role of these metabolic adaptations on the AML pathogenesis is still controversial. In this work, the metabolic status and the respective metabolic networks operating in different AML cells (NB-4, HL-60 and KG-1) and their impact on autophagy and survival was characterized. Data show that whereas KG-1 cells exhibited preferential mitochondrial oxidative phosphorylation metabolism with constitutive co-activation of AMPK and mTORC1 associated with increased autophagy, NB-4 and HL-60 cells displayed a dependent glycolytic profile mainly associated with AKT/mTORC1 activation and low autophagy flux. Inhibition of AKT is disclosed as a promising therapeutical target in some scenarios while inhibition of AMPK and mTORC1 has no major impact on KG-1 cells' survival. The results highlight an exclusive metabolic profile for each tested AML cells and its impact on determination of the anti-leukaemia efficacy and on personalized combinatory therapy with conventional and targeted agents.This work was developed under the scope of the project NORTE‐01‐0145‐FEDER‐000013, supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER), and by FEDER, through the Competitiveness Factors Operational Programme (COMPETE), and by National funds, through the Foundation for Science and Technology (FCT), under the scope of the project POCI‐01‐0145‐FEDER‐007038. OP and BSM are supported by fellowships from the Fundação para a Ciência e Tecnologia (FCT, Portugal) (SFRH/BD/52292/2013 and SFRH/BPD/90533/2012, respectively)info:eu-repo/semantics/publishedVersio
Reasons and benefits associated with ISO 9001 - Certification for sugar and ethanol companies
With increasing business competitiveness, companies have sought to adapt their processes and / or products to worldwide established quality standards in order to achieve a greater share of consumers having as favorable aspect the quality assurance of the products and/or services provided. It was observed that companies of different sizes have different challenges regarding the certification however, the degree of difficulty is the same for all of them. The objective of this paper is to verify the reasons for the implementation of ISO 9001, the obstacles encountered during the implementation, the benefits arising from the use of the quality management system and the degree of difficulty to implement this standard. This work was developed based on a survey involving companies certified with ISO 9001:2008 from the productive sector of sugar, ethanol and derivatives of sugarcane, located in all Brazilian states. It was observed that companies of different sizes have different challenges regarding the certification however the degree of difficulty is the same for all of them. Thus, we believe that expected results represent a very important contribution to examining the reasons, benefits and difficulties of the ISO 9001 to both, the companies and certification bodies, and to researchers.CAPES Foundation, (Process PE024/2008), the FAPEMIG Foundation (Processes: T EC-PPM-00520/13 and TEC-PPM-000 58-13) and the CNPq (Processes: 2 49160/2013-7, 310660/ 2012-2, 401082/2 014-8 and 478509/2012-
Reasons, benefits and difficulties associated with ISO 9001 certification for sugar and ethanol companies
Purpose: With increasing business competitiveness, companies have sought to adapt their processes
and / or products to worldwide established quality standards in order to achieve a greater share of
consumers having as favorable aspect the quality assurance of the products and/or services provided. It
was observed that companies of different sizes have different challenges regarding the certification
however, the degree of difficulty is the same for all of them. The objective of this paper is to verify the
reasons for the implementation of ISO 9001, the obstacles encountered during the implementation, the
benefits arising from the use of the quality management system and the degree of difficulty to implement
this standard.
Design/methodology/approach: This work was developed based on a survey involving companies
certified with ISO 9001:2008 from the productive sector of sugar, ethanol and derivatives of sugarcane,
located in all Brazilian states.
Findings: It was observed that companies of different sizes have different challenges regarding the
certification however the degree of difficulty is the same for all of them.
Originality/value: Thus, we believe that expected results represent a very important contribution to
examining the reasons, benefits and difficulties of the ISO 9001 to both, the companies and certification
bodies, and to researchers
Impact Assessment of Urethral Meatus Morphology and Penile Biometry in Transurethral Prostate and Bladder Surgery
Objective. To analyze the penile and urethral meatus biometry and its correlation with meatoplasty during endoscopic resections. We also propose a new classification for urethral meatus morphology. Materials and Methods. We prospectively studied 105 patients who underwent prostate and bladder transurethral resections. We performed standardized measurement of penile and urethral meatus biometry followed by penile photo in the front position. The need to perform meatoplasty or dilatation during resectoscope introduction was registered. Data were analyzed comparing the correlation between two groups: without intervention (Group A) and with intervention (Group B). Results. We observed in Group A and Group B, respectively, the average length of urethral meatus of 1.07 cm versus 0.75 cm (p<0.001) and average width of urethral meatus of 0.59 cm versus 0.38 cm (p<0.001). Considering the morphology of the urethral meatus, we propose a new classification, in the following groups: (a) typical; (b) slit; (c) point-like; (d) horseshoe; and (e) megameatus. The point-like meatus was the one that most needed intervention, followed by the slit and the typical meatus (p<0.001). Conclusions. Point-like and slit-shaped urethral meatus, as well as reduced length and width of the urethral meatus, are the determining factors
Relato de experiência da feira de produtos orgânicos de Juazeiro do Norte: caracterização de seus consumidores
A produção de alimentos orgânicos está ligada as práticas da agricultura limpa, caracterizada pela produção de alimentos sem agrotóxicos e metodologias que superam problemas gerados pelas inovações tecnológicas, estabelecendo o equilíbrio ecológico do sistema agrícola. Então, surgem as feiras livres de produtos orgânicos como a de Juazeiro do Norte-Ceará. Objetivou-se com esta pesquisa caracterizar o público consumidor que frequenta a feira e traçar seu perfil. Para isto, realizou-se um levantamento de dados por meio de entrevistas diretas aos consumidores no espaço de comercialização. Onde foram indagados a questões como: frequência na feira e percepção sobre comercialização de orgânicos. Com a pesquisa, obteve-se um perfil onde os principais consumidores são mulheres de escolaridade básica e frequentam a feira por considerarem os produtos saudáveis. Os dados aqui levantados podem ser utilizados como referência para melhoria dos serviços e produtos destinados a esses consumidores.Eje: B3 Economía y agroecología (Relatos de experiencias)Facultad de Ciencias Agrarias y Forestale
Relato de experiência da feira de produtos orgânicos de Juazeiro do Norte: caracterização de seus consumidores
A produção de alimentos orgânicos está ligada as práticas da agricultura limpa, caracterizada pela produção de alimentos sem agrotóxicos e metodologias que superam problemas gerados pelas inovações tecnológicas, estabelecendo o equilíbrio ecológico do sistema agrícola. Então, surgem as feiras livres de produtos orgânicos como a de Juazeiro do Norte-Ceará. Objetivou-se com esta pesquisa caracterizar o público consumidor que frequenta a feira e traçar seu perfil. Para isto, realizou-se um levantamento de dados por meio de entrevistas diretas aos consumidores no espaço de comercialização. Onde foram indagados a questões como: frequência na feira e percepção sobre comercialização de orgânicos. Com a pesquisa, obteve-se um perfil onde os principais consumidores são mulheres de escolaridade básica e frequentam a feira por considerarem os produtos saudáveis. Os dados aqui levantados podem ser utilizados como referência para melhoria dos serviços e produtos destinados a esses consumidores.Eje: B3 Economía y agroecología (Relatos de experiencias)Facultad de Ciencias Agrarias y Forestale
Perfil do enfermeiro de terapia intensiva em diferentes regiões do Brasil
The aim of this quantitative study was to identify the socio-demographic and academic profile of intensive care registered nurses and participants of the events organized by the Department of Nursing of the Brazilian Association of Intensive Care Medicine. Data were collected by means of 400 questionnaires applied between January and July of 2010, however only 324 questionnaires were returned and 295 questionnaires were considered for the analysis. Data were analyzed with descriptive statistics resources with absolute relative frequency and simple mean, presented in tables. Results show the predominance of women, with specific graduate degrees. The skills and values highlighted include technical and scientific knowledge, and leadership. These professionals seek work in intensive care because of the high technological complexity. The study emphasized the existence of the professional profile required to work in the intensive care unit. The qualification of these professionals must prioritize the mastering of the technological language and the comprehensive and safe care.Investigación cuantitativa cuyo objetivo fue identificar el perfil sociodemográfico y académico de los enfermeros intensivistas asociados y participantes en eventos promovidos por el Departamento de Enfermería de la Asociación de Medicina Intensiva Brasileña. La recolección de datos se dio por medio de la distribución de 400 cuestionarios, en el período de enero a julio de 2010. Retornaron 324 cuestionarios y solo se consideraron para el análisis 295. Los datos fueron analizados con recursos de estadística descriptiva de frecuencia absoluta relativa y medias simples presentadas en tablas. Los resultados evidencian el predominio de sexo femenino, con formación de Post-Grado Lato Sensu, específico en el área. Dentro de las competencias se valorizan el conocimiento técnico científico y liderazgo. Estos profesionales buscan actuar en la terapia intensiva por la alta complejidad tecnológica. Se admite la existencia de un perfil profesional para trabajar en la unidad de terapia intensiva. La calificación profesional debe priorizar el dominio del lenguaje tecnológico y la asistencia integral y segura.Pesquisa quantitativa cujo objetivo foi identificar o perfil sociodemográfico e acadêmico dos enfermeiros intensivistas associados e participantes de eventos promovidos pelo Departamento de Enfermagem da Associação de Medicina Intensiva Brasileira. Coleta de dados efetivada por meio da distribuição de 400 questionários, no período de janeiro a julho de 2010. Retornaram 324 questionários, e considerou-se para análise 295 questionários. Os dados foram analisados com recursos da estatística descritiva com a frequência absoluta relativa e a média simples, apresentados em tabelas. Os resultados evidenciam o predomínio do sexo feminino, com formação em curso de Pós-Graduação Lato Sensu específico na área. Dentre as competências, valoriza-se o conhecimento técnico-científico e a liderança. Estes profissionais buscam atuar na terapia intensiva pela alta complexidade tecnológica. Admite-se a existência de um perfil profissional para trabalhar em unidade de terapia intensiva. A qualificação profissional deve priorizar o domínio da linguagem tecnológica e a assistência integral e segura.Federal University of São Paulo Escola Paulista de EnfermagemFederal University of Santa CatarinaUNIFESP EPEUFSCSchool of Management and Health SciencesUNIFESP, Escola Paulista de Enfermagem (EPE)SciEL
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