339 research outputs found

    Reproductive Health Issues AfTecting Displaced Populations

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    The provision of reproductive health services for displaced populations has gained momentum since the 1994 International Conference on Population and Development (ICPD). The ICPD Programme of Action sets reproductive health within a rights framework and highlights the needs of refugees and internally displaced populations. This paper looks at the background to reproductive health for refugees, offers some lessons learned from Marie Stopes International's refugee programming experience and highlights possible future interventions.La prise en compte des questions d'obstétrique pour les personnes déplacées a gagné un surcroît d'attention depuis la Conférence Internationale sur la population et le Développement de 1994. Le programme d'action ayant découlé de cette conférence place l'obstétrique dans le cadre adéquat et met en relief les besoins des réfugiés et des personnes déplacées à l'intérieur des frontières nationales. Cet article propose un rappel historique de la question de l'obstétrique pour les réfugiés, suggère quelques leçons à tirer de l'expérience d'organisation des réfugiés de Marie Stopes International, et signale les interventions futures possibles

    Space Solar Power with SunSynchronous Orbits

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    The basic problem being addressed here is the high initial cost of solar power satellite (SPS) systems. The cost is higher for GEO orbits because of the large solar array and transmitter sizes required from that distance, and the expense of lifting such a mass into the higher orbits. Aperture size is proportional to the distance the power is beamed; thus transmitter apertures can be smaller when nearer to Earth. Decreasing the distance energy must be beamed through space means that the powersat need not be so large, or as expensive. Implementation of sunsynchronous sunsats will likely be a more complex operation, but this limitation is lessened by the cost savings resulting from the smaller mass to be delivered to lower, more accessible orbits. The development of an economically viable space energy system on a global basis is made more attainable using satellites equipped with equatorial orbiting reflectors for the sharing of energy. The development of wireless power transmission (WPT) is critical to the emergence of sustainable private and government space ventures, including space lift, space exploration and space development. The pursuit of space-based solar power in the lower orbits will greatly expand the need for space lift capability which will help to accelerate these developments. Advisors: Royce Jones, Prof. Don Flournoy, John Bowditch Space Solar Power with SunSynchronous Orbits from Space Communication Journal on Vimeo

    The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

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    Correction to Dolan J, Walshe K, Alsbury S, Hokamp K, O'Keeffe S, Okafuji T, Miller SF, Tear G, Mitchell KJ: The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns. BMC Genomics 2007, 8:320

    Mycobacterium bovis genomics reveals transmission of infection between cattle and deer in Ireland

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    Control of bovine tuberculosis (bTB), caused by Mycobacterium bovis, in the Republic of Ireland costs €84 million each year. Badgers are recognised as being a wildlife source for M. bovis infection of cattle. Deer are thought to act as spillover hosts for infection; however, population density is recognised as an important driver in shifting their epidemiological role, and deer populations across the country have been increasing in density and range. County Wicklow represents one specific area in the Republic of Ireland that has had consistently high bTB prevalence for over a decade, despite control operations in both cattle and badgers. The area is also known to have a high density of deer. Our research used whole genome sequencing of M. bovis sourced from infected cattle, deer, and badgers in County Wicklow to evaluate whether the epidemiological role of deer could have shifted from spillover host to source. Our analyses reveal that cattle and deer share highly similar M. bovis strains suggesting that transmission between these species is occurring in the area. In addition, the high level of diversity observed in the sampled deer population suggests deer may be acting as a source of infection for local cattle populations. These findings have important implications for the control and ultimate eradication of bTB in Ireland

    Applying a WASH risk assessment tool in a rural South African setting to identify risks and opportunities for climate resilient communities

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    Climate change threatens the health and well-being of populations. We conducted a risk assessment of two climate-related variables (i.e., temperature and rainfall) and associated water, sanitation and hygiene (WASH)-related exposures and vulnerabilities for people living in Mopani District, Limpopo province, South Africa. Primary and secondary data were applied in a qualitative and quantitative assessment to generate classifications of risk (i.e., low, medium, or high) for components of hazard/threat, human exposure, and human vulnerability. Climate-related threats were likely to impact human health due to the relatively high risk of waterborne diseases and WASH-associated pathogens. Vulnerabilities that increased the susceptibility of the population to these adverse outcomes included environmental, human, physical infrastructure, and political and institutional elements. People of low socio-economic status were found to be least likely to cope with changes in these hazards. By identifying and assessing the risk to sanitation services and water supply, evidence exists to inform actions of government and WASH sector partners. This evidence should also be used to guide disaster risk reduction, and climate change and human health adaptation planning.DATA AVAILABILITY STATEMENT : The laboratory sample data are available from the National Health Laboratory Services. All hazard-related data were extracted from publicly available manuscripts as cited in the text.The South African Medical Research Council and the National Research Foundation. The A.P.C. was funded by the South African Medical Research Council.https://www.mdpi.com/journal/ijerphGeography, Geoinformatics and Meteorolog

    Bulla Regia II : Excavations in the Christian cemetery

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    This paper reports the preliminary results from three seasons of excavations in the Christian cemetery by the Tunisian-British Bulla Regia Archaeological Project. In 2017-2019, excavations in, and around, the Late Antique church in the western cemetery uncovered a complex funerary landscape with a variety of different tomb types, including mosaic caisson tombs, simple masonry tombs, amphora tombs, and earthen graves and multiple funerary mensae. The mosaics, inscriptions and finds (ceramics, glass, coins) studied in 2022 support a fourth to seventh century date for the main period of use of the cemetery

    Global population genomics of two subspecies of Cryptosporidium hominis during 500 years of evolution

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    Cryptosporidiosis is a major global health problem and a primary cause of diarrhoea, particularly in young children in low- and middle-income countries (LMICs). The zoonotic Cryptosporidium parvum and anthroponotic C. hominis cause most human infections. Here, we present a comprehensive whole-genome study of C. hominis, comprising 114 isolates from 16 countries within five continents. We detect two lineages with distinct biology and demography, which diverged circa 500 years ago. We consider these lineages two subspecies and propose the names C. hominis hominis and C. hominis aquapotentis (gp60 subtype IbA10G2). In our study, C. h. hominis is almost exclusively represented by isolates from LMICs in Africa and Asia and appears to have undergone recent population contraction. In contrast, C. h. aquapotentis was found in high-income countries, mainly in Europe, North America and Oceania, and appears to be expanding. Notably, C. h. aquapotentis is associated with high rates of direct human-to-human transmission, which may explain its success in countries with well-developed environmental sanitation infrastructure. Intriguingly, we detected genomic regions of introgression following secondary contact between the subspecies. This resulted in high diversity and divergence in genomic islands of putative virulence genes (GIPVs), including muc5 (CHUDEA2_430) and a hypothetical protein (CHUDEA6_5270). This diversity is maintained by balancing selection, suggesting a coevolutionary arms race with the host. Lastly, we find that recent gene flow from C. h. aquapotentis to C. h. hominis, likely associated with increased human migration, may be driving evolution of more virulent C. hominis variants
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