A disseminated variant of pancreatic serous cystadenoma causing obstructive jaundice, a very rare entity: a case report and review of the literature

BACKGROUND: Microcystic adenoma or serous cystadenoma (SCA) is an uncommon tumor type, accounting for only 1–2% of pancreatic exocrine neoplasms. Usually unifocal, SCAs present as single, large, well-demarcated, multiloculated, cystic tumors, 1–25 cm in size. CASE PRESENTATION: A 73-year-old man initially presented with epigastric abdominal pain and was diagnosed with SCA involving the whole pancreas. Eleven months later, he presented with obstructive jaundice, and total pancreatectomy was performed. The removed tissue allowed histological verification of pancreatic SCA. Histopathological examination showed both microcysts and macrocysts, lined by cuboidal epithelium, with optically clear cytoplasm and the absence of detectable mitosis or necrosis. CONCLUSIONS: Thus, although relatively rare, pancreatic SCA is one of the differential diagnoses of epigastric abdominal pain; we recommend early surgical intervention for symptomatic pancreatic SCA

Study of Changes in Cholesterol 7 Alpha Hydroxylase in Patients with Gall Stone in Babylon Province

المرارة (GB) هوالجهازالمساعدمنالجهاز الهضمي،وهي تقعتحتالكبد وتعلق علىنظامالصفراوي،وأنها مسؤولة عنالتحكم فيإطلاقالصفراءوالتخزين. مرضحصوةمشكلة صحية كبيرةفي جميع أنحاء العالم. في 10-15٪ من البالغيناحتواءمرضحصوة. هذه الدراسة (مراقبةحالة) ويتكون من 160 (160) وشملتالمرضىفيهذه الدراسةتم اختيارها عشوائيا، ويتألفمن 130 من الإناث و 30 من الذكور. ويتم فحصجميع المرضى 24 ساعة. قبل العملية،داخلالجراحةوبعدالجراحة 24hr. انخفاضالحركةالمرارةوانخفاضالكولسترول 7 -alpha النشاطهيدروكسيلاز،التي تنظمنوفوتوليفالصفراء الملح. والحد من معدل خطوةمنتركيب الحامض المرارييتصرفبين 7A1 CYP الكبدمعين (CYP450). وهكذا،والتعديلاتفي السيطرةالجينات CYP أيضا له تأثيرعلىتركيب الحامض المراريوالتمثيل الغذائي للدهون.The gallbladder (GB) is an assistant organ of the digestive system, It is  located under the liver and attached to the biliary system, And it is responsible for controlling release of bile and the storage. Gallstone disease a major health problem worldwide. In 10–15% of adults contain gallstone disease. This study (case control) consists of  one hundred sixty (160) patients are included in this study randomly selected  and consisted of 130 females and 30 males. All patients are examined 24 hr. Before operation, Intra operatively and 24hr post operatively. Decreased gallbladder motility and the decrease of cholesterol 7 –alpha hydroxylase activity, which regulate the novo bile salt synthesis. The rate-limiting step of bile acid synthesis is acting between the liver-specific CYP 7A1 (CYP450). Thus, Alteration in CYP gene control also has an impact on bile acid synthesis and lipid metabolism

Screening for Antibacterial Activity of Andrographis paniculata Used in Malaysian Folkloric Medicine: A Possible Alternative for the Treatment of Skin Infections

In this study non-polar (dichloromethane) and polar (MeOH & aqueous) extracts of A. paniculata (whole plant) were evaluated for in vitro antibacterial activity against 12 skin disease causing bacterial strains (7 gram positive strains; Staphylococcus saprophyticus, Staphylococcus epidermis, Staphylococcus aureus, Streptococcus pyogenes, Bacillus anthracis, Micrococcus luteus, Enterococcus faecalis) and 5 gram negative strains; Proteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae, Neisseria meningitis, Pseudomonas aeruginosa ) using the disc diffusion method at three concentrations; 1000, 500, and 250 μg/disc respectively in order to ascertain its folkloric claim to treat skin infections. The extracts showed significant antibacterial activities against both the Gram-positive and Gram-negative bacterial strains tested. Highest significant antibacterial activity was exerted by the MeOH extract against E. faecalis at 1000 μg/disc (24.00 ± 0.00 mm) and the least activity by the DCM extract against N. meningitis at 250 μg/disc (6.00 ± 0.00mm). The minimum inhibitory concentration ranged between 150 μg /mL and 300 μg /mL depending on microorganism and various extracts. Presence of phytochemicals such as terpenoids, tannins, flavonoids, saponins, alkaloids, amino acids and steroids were observed. These results candidly suggest the presence of promising antibacterial substances in the polar as well as non-polar extracts which could be potential phytomedicine for the treatment of skin infections caused by pathogenic bacterial strains. These findings explicitly support its traditional claims and form a strong basis for further efforts to explore A. paniculata’s antibacterial potential to treat skin frailties efficaciously. Our results confer the utility of this plant extracts in developing a novel broad spectrum antimicrobial agent

Étude expérimentale de la formulation de mortier a base de sable silteux du Togo et de liant de sachets plastiques type « voltic »

La présente étude est destinée à valoriser les déchets plastiques par la recherche d’une formule optimale de mortier à base de sable silteux du Togo et de sachets plastiques fondus du type « voltic » offrant des propriétés mécaniques optimales. Trente six (36) échantillons de mortier à base de mélange de sable silteux et de liant de sachets plastiques à des dosages variant de 7% à 28% ont été préparés et soumis aux essais physiques et mécaniques après imbibition ou non dans de l’eau. Il ressort des résultats que le dosage en liant de sachets plastiques offrant de résistance optimale en compression (σc), au fendage (τd), en traction par flexion (σf) et par fendage (σd) varient de 16% à 22% avec des résistances à la rupture respectives d’environ 10,3 MPa (à 22%), 2,2 MPa (à 16%), 5,3 MPa (à 18%) et 1,4 MPa (à 16%). Le matériau présente des modules d’élasticité en compression (Ec), en flexion (Ef) et au fendage (Gd) respectivement d’environ 3 800 MPa, 700 MPa et 60 MPa pour des taux de liants de 22%. Pour de faibles taux de liants (8 à 10%), la densité du mortier et son absorption d’eau (en masse) sont optimales (respectivement de 1,95% et 0,29%). Cette absorption d’eau est nulle pour les teneurs en liant supérieures à 18% montrant le comportement étanche des mortiers. Les mortiers peuvent donc être utilisés pour les travaux de pavages, d’étanchement des toitures et de murs pour des taux de liants compris entre 18 à 22%.Mots-clés : mortier, sachets plastiques, sable silteux, eau, propriétés physico-mécaniques

Composition and Distribution of Aquatic Weeds in some Minor Canals, Gezira Scheme, Sudan (2018)

Excessive growth of aquatic weeds in irrigation systems is a worldwide problem. In Sudan, many irrigation schemes have been greatly affected by aquatic weeds such as Gezira scheme. The objective of the study was to evaluate the community composition and distribution of aquatic weeds in some minor canals in the Gezira scheme in 2018. The study area covered six minor canals at Centre Group at Gezira Scheme. Each minor canal was divided into three sections%253B head, middle and tail (18 sampling sites). The sites were surveyed once in every month for a period of three months during summer and winter seasons. The community composition of aquatic weeds was detected by visual observation, whereas the distribution of aquatic weeds was determined by calculation of percentage of relative frequency. Data were subjected to descriptive analysis and to analysis of variance. The results indicated that the community composition in the six minor canals consists of four groups of aquatic weeds as follows%253B floating, emergent, submergent and bank aquatic weeds and consisted of 12 species belonging to nine families. Results showed considerable differences in distribution throughout the year. The most dominant species within the groups were%253B Vossia cuspidata (33%25 - 41%25) within the group of floating weeds, Cyperus alopecuroides (87%25 - 55%25) within the group of emergent weeds and Cynodon dactylon (75%25 - 83%25) within the group of bank aquatic weeds during both summer and winter seasons. Submergent weeds present only in winter season in one species Najas pectinata. Also, results of relative frequency within all aquatic species showed that Vossia cuspidata and Cynodon dactylon were the most dominant species. These finding gives many insights about the problems of aquatic weeds in minor canals and would be useful in the management and control of aquatic weeds

Response of Matured Tissue Cultured Bartemoda and SakkotiDate Palms to Spraying Vitamins K, A& B

Abstract: This study was carried out during 2013 and 2014 seasons to test the beneficial effects of using vitamins K, B, A each at 50 ppm on yield and fruit quality of matured tissue cultured Sakkoti and Bartemoda date palms grown under Aswan conditions. The palms were sprayed four times at the first week of Feb April, June and August. Single and combined applications of vitamins K, A , B each at 50 ppm materially caused an obvious promotion on all vegetative growth characters, chlorophylls a & b , total chlorophylls, total carotenoids, total carbohydrates %, nutrients , flowering , fruit setting %, yield and fruit quality in both cvs. over the check treatment. The best vitamin in this respect was vitamin B followed by vitamin A and K. The studied vitamin treatments had pronounced effect on advancing harvesting date in both date palms cvs. Treating matured tissue cultured Sakkoti and Bartemoda date palms grown under Aswan conditions four times with a mixture of vitamins K, A, B each at 50 ppm proved to be very effective in improving yield and fruit quality

The Arabic Version of the Impact of Event Scale-Revised : psychometric evaluation among psychiatric patients and the general public within the context of COVID-19 outbreak and quarantine as collective traumatic events

The Coronavirus Disease-19 (COVID-19) pandemic has provoked the development of negative emotions in almost all societies since it first broke out in late 2019. The Impact of Event Scale-Revised (IES-R) is widely used to capture emotions, thoughts, and behaviors evoked by traumatic events, including COVID-19 as a collective and persistent traumatic event. However, there is less agreement on the structure of the IES-R, signifying a need for further investigation. This study aimed to evaluate the psychometric properties of the Arabic version of the IES-R among individuals in Saudi quarantine settings, psychiatric patients, and the general public during the COVID-19 outbreak. Exploratory factor analysis revealed that the items of the IES-R present five factors with eigenvalues > 1. Examination of several competing models through confirmatory factor analysis resulted in a best fit for a six-factor structure, which comprises avoidance, intrusion, numbing, hyperarousal, sleep problems, and irritability/dysphoria. Multigroup analysis supported the configural, metric, and scalar invariance of this model across groups of gender, age, and marital status. The IES-R significantly correlated with the Depression Anxiety Stress Scale-8, perceived health status, and perceived vulnerability to COVID-19, denoting good criterion validity. HTMT ratios of all the subscales were below 0.85, denoting good discriminant validity. The values of coefficient alpha in the three samples ranged between 0.90 and 0.93. In path analysis, correlated intrusion and hyperarousal had direct positive effects on avoidance, numbing, sleep, and irritability. Numbing and irritability mediated the indirect effects of intrusion and hyperarousal on sleep and avoidance. This result signifies that cognitive activation is the main factor driving the dynamics underlying the behavioral, emotional, and sleep symptoms of collective COVID-19 trauma. The findings support the robust validity of the Arabic IES-R, indicating it as a sound measure that can be applied to a wide range of traumatic experiences

Fisheries and biodiversity along Mediterranean Sea: Italian and Egyptian coast overview

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Effect of addition of exogenous enzymes in hypocaloric diet in broiler chicken on performance, biochemical parameters and meat characteristics

In developing countries, broiler farmers often use imbalanced energy diets, hence our study aims to evaluate the combined effect of addition of commercial exogenous enzymes (CEE), in low energy level corn/soybean meal based-diet on performance, serum biochemical parameters, meat characteristics in male and female of broiler chickens. A total of 120 one day old Hubbard F15 broiler chickens were divided on 2 groups (60 animals/group) with 5 replicates/group. The control group received a standard diet, while CEE group received the same diet supplemented with enzymes (250 g/ton). Addition of enzymes reduced significantly feed (p<0.001) and water intakes (p<0.05); in meantime, feed conversion ratio tended to be lower (p=0.08). No changes were observed in pH, protein or moisture contents of meat in both sexes broiler between CEE and control groups. No perturbation was found in all serum biochemical parameters in both sexes between CEE and control groups, except total protein and albumin levels were significantly higher in male birds fed enzymes when compared to male birds of the control group (p<0.001; p<0.01) respectively. Addition of enzymes allowed a decrease of 950 g/bird in feed intake for the total rearing period, hence save 337 €/1000 birds; thus, use of CEE in hypocaloric diet enhances broilers feed efficiency and procures an economic benefit to farmers