91 research outputs found

    Social and Economic Security and National Development

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    The symposium on Social Research for Development was held on May 5-11, 1981, in Cairo, Egypt; by the Social Research Center (SRC) of The American University in Cairo (AUC). The Symposium was supported by funds from Battelle Human Affairs Research Center, Ford Foundation, International Development Re­search Center {IDRC}, and the Population Council. The theme of the Symposium was selected in respons.e to the increased con­cerns of social scientists, policymakers and funding agencies about the current status and new directions of social science research, its role in the pro­cess of social and economic development, and its contribution to policy-rele­vant issues. The Symposium, therefore, aimed at providing a valuable opportu­nity for the invaed participants to exchange ideas and views on social research findings, methodologies, priorities, strategies, and funding as they relate to policy issues of various aspects of social and economic developmenthttps://fount.aucegypt.edu/faculty_book_chapters/1832/thumbnail.jp

    Modulation of muscle pain is not somatotopically restricted : an experimental model using concurrent hypertonic-normal saline infusions in humans

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    We have previously shown that during muscle pain induced by infusion of hypertonic saline (HS), concurrent application of vibration and gentle brushing to overlying and adjacent skin regions increases the overall pain. In the current study, we focused on muscle-muscle interactions and tested whether HS-induced muscle pain can be modulated by innocuous/sub-perceptual stimulation of adjacent, contralateral, and remote muscles. Psychophysical observations were made in 23 healthy participants. HS (5%) was infused into a forearm muscle (flexor carpi ulnaris) to produce a stable baseline pain. In separate experiments, in each of the three test locations (n = 10 per site)—ipsilateral hand (abductor digiti minimi), contralateral forearm (flexor carpi ulnaris), and contralateral leg (tibialis anterior)—50 μl of 0.9% normal saline (NS) was infused (in triplicate) before, during, and upon cessation of HS-induced muscle pain in the forearm. In the absence of background pain, the infusion of NS was imperceptible to all participants. In the presence of HS-induced pain in the forearm, the concurrent infusion of NS into the ipsilateral hand, contralateral forearm, and contralateral leg increased the overall pain by 16, 12, and 15%, respectively. These effects were significant, reproducible, and time-locked to NS infusions. Further, the NS-evoked increase in pain was almost always ascribed to the forearm where HS was infused with no discernible percept attributed to the sites of NS infusion. Based on these observations, we conclude that intramuscular infusion of HS results in muscle hyperalgesia to sub-perceptual stimulation of muscle afferents in a somatotopically unrestricted manner, indicating the involvement of a central (likely supra-spinal) mechanism

    Impact Of Tuberculosis Upon Patients’ Quality Of Life Who Undergo Directly Observed Treatment Short Course(DOTS) In AL-Amarah City

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    Abstract Objective: To find the impact of Tuberculosis disease upon quality of life of patients who undergo Directly Observed Treatment Short Course (DOTS).                Methodology: A descriptive design is carried out at Respiratory and Chest Diseases out Patients’ Clinic, from Nov 20th, 2012 to July 11th, 2013, in order to find out the impact of tuberculosis disease upon quality of life of patients who undergo Directly Observed Treatment Short Course (DOTS). A non-probability (Purposive) sample of (60) Tuberculosis patients. The data collection process has been performed from February 13th, 2012 to the April 6th, 2012. The data were described analyzed through the use of descriptive statistics such as (frequencies, percentage, mean of score and comparative significant) and inferential statistics such as (Chi-square, and T-test).                          Results: The results of the study showed that Tuberculosis negatively influence upon patients quality of life domains.Conclusion: The study concludes that the maximum effect of presented by the social domain, followed by the psychological, level of independency, then the physical domain. While the minimum impact, presented by spiritual domain, followed by the environmental domain.                                      Recommendation: The study recommended that necessary to do a health educational programs to increase health awareness among peoples who attendants the outpatient clinics and special health centers for tuberculosis disease, as well as the use of mass media by the health authorities.Key words: Quality of life (QoL); Tuberculosis (TB); Directly Observed Treatment Short Course (DOTS

    Investigating pronouns: the use of “we” in Secondary School Students’ essay writing

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    The present study is an attempt to analyze the linguistic constituent; pronoun,B“we” as stated in the essays written by third year secondary students of Arab Republic of Egypt in two Secondary schools. As the study under investigation depends so much on a corpus and descriptive analysis, it explores the L2 output of learners in their writing of essay compositions context. It provides examples of pronouns employed by the students. This particular study was aimed at investigating pronouns’ frequencies, the singular Pronouns, and the Plural Pronouns of the written texts, highlighting the students’ understanding of making use of this linguistic constituent when they write. A corpus-based learner utilized a corpus investigation that has tagging and a frequency of part of speech (POS) of examination employing a software known as concordance will be the scheme of analysis. The results depicted an over-use of the 1st person plural as a subjective personal pronoun (we). The analysis discussion of the pedagogical contribution will be introduced

    Psychophysical Investigations into the Role of Low-Threshold C Fibres in Non-Painful Affective Processing and Pain Modulation

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    We recently showed that C low-threshold mechanoreceptors (CLTMRs) contribute to touch-evoked pain (allodynia) during experimental muscle pain. Conversely, in absence of ongoing pain, the activation of CLTMRs has been shown to correlate with a diffuse sensation of pleasant touch. In this study, we evaluated (1) the primary afferent fibre types contributing to positive (pleasant) and negative (unpleasant) affective touch and (2) the effects of tactile stimuli on tonic muscle pain by varying affective attributes and frequency parameters. Psychophysical observations were made in 10 healthy participants. Two types of test stimuli were applied: stroking stimulus using velvet or sandpaper at speeds of 0.1, 1.0 and 10.0 cm/s; focal vibrotactile stimulus at low (20 Hz) or high (200 Hz) frequency. These stimuli were applied in the normal condition (i.e. no experimental pain) and following the induction of muscle pain by infusing hypertonic saline (5%) into the tibialis anterior muscle. These observations were repeated following the conduction block of myelinated fibres by compression of sciatic nerve. In absence of muscle pain, all participants reliably linked velvet-stroking to pleasantness and sandpaper-stroking to unpleasantness (no pain). Likewise, low-frequency vibration was linked to pleasantness and high-frequency vibration to unpleasantness. During muscle pain, the application of previously pleasant stimuli resulted in overall pain relief, whereas the application of previously unpleasant stimuli resulted in overall pain intensification. These effects were significant, reproducible and persisted following the blockade of myelinated fibres. Taken together, these findings suggest the role of low-threshold C fibres in affective and pain processing. Furthermore, these observations suggest that temporal coding need not be limited to discriminative aspects of tactile processing, but may contribute to affective attributes, which in turn predispose individual responses towards excitatory or inhibitory modulation of pain

    Assessing disparities in medical students’ knowledge and attitude about monkeypox: a cross-sectional study of 27 countries across three continents

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    Background and aimsThe recent monkeypox (Mpox) outbreak confirmed by the World Health Organization (WHO) underscores the importance of evaluating the knowledge and attitude of medical students toward emerging diseases, given their potential roles as healthcare professionals and sources of public information during outbreaks. This study aimed to assess medical students’ knowledge and attitude about Mpox and to identify factors affecting their level of knowledge and attitude in low-income and high-income countries.MethodsA cross-sectional study was conducted on 11,919 medical students from 27 countries. A newly-developed validated questionnaire was used to collect data on knowledge (14 items), attitude (12 items), and baseline criteria. The relationship between a range of factors with knowledge and attitude was studied using univariate and multivariate analyses.Results46% of the study participants were males; 10.7% were in their sixth year; 54.6% knew about smallpox; 84% received the coronavirus disease 2019 (COVID-19) vaccine; and 12.5% had training on Mpox. 55.3% had good knowledge of Mpox and 51.7% had a positive attitude towards it. Medical students in their third, fifth, or sixth year high- income countries who obtained information on Mpox from friends, research articles, social media and scientific websites were positive predictors for good knowledge. Conversely, being male or coming from high-income countries showed a negative relation with good knowledge about Mpox. Additionally, a positive attitude was directly influenced by residing in urban areas, being in the fifth year of medical education, having knowledge about smallpox and a history of receiving the coronavirus disease 2019 (COVID-19) vaccine. Receiving information about Mpox from social media or scientific websites and possessing good knowledge about Mpox were also predictors of a positive attitude. On the other hand, being male, employed, or receiving a training program about Mpox were inversely predicting positive attitude about Mpox.ConclusionThere were differences in knowledge and attitude towards Mpox between medical students in low and high-income countries, emphasizing the need for incorporating epidemiology of re-emerging diseases like Mpox into the medical curriculum to improve disease prevention and control

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
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