Using Unlabeled Data for Increasing Low-Shot Classification Accuracy of Relevant and Open-Set Irrelevant Images

In search exploration and reconnaissance tasks performed with autonomous ground vehicles an image classification capability is needed for specifically identifying targeted objects relevant classes and at the same time recognize when a candidate image does not belong to anyone of the relevant classes irrelevant images In this paper we present an open-set low-shot classifier that uses during its training a modest number less than 40 of labeled images for each relevant class and unlabeled irrelevant images that are randomly selected at each epoch of the training process The new classifier is capable of identifying images from the relevant classes determining when a candidate image is irrelevant and it can further recognize categories of irrelevant images that were not included in the training unseen The proposed low-shot classifier can be attached as a top layer to any pre-trained feature extractor when constructing a Convolutional Neural Networ

Romanian Tritium for Nuclear Fusion

The demand for tritium is expected to increase when ITER (the International Thermonuclear Experimental Reactor) begins operation in the mid-2020s. Romania is expected to detritiate its CANDU (Canada Deuterium Uranium) units at Cernavoda starting 2024, with the goal of improving radiological safety and reactor performance. Detritiation will result in a significant quantity of tritium being produced and thus Romania has an opportunity to supply tritium for fusion. In this assessment, ITER has been used as a reference device requiring tritium, as the projected tritium extraction schedule from Cernavoda aligns favourably with ITER operation. The findings suggest that Romania is capable of providing a total of 6.2 kg of tritium to ITER over its 20 year operation, generating a potential revenue of $186 M (USD). Opportunities associated with the supply of Romanian helium-3 are also considered as a hedging option, which has the potential to generate$120 M (USD) in the case of zero tritium sales. Greater involvement in future fission-fusion tritium-related activities through experience in tritium technologies is also discussed as a unique opportunity for Romania

The Invariance Hypothesis Implies Domain-Specific Regions in Visual Cortex

Is visual cortex made up of general-purpose information processing machinery, or does it consist of a collection of specialized modules? If prior knowledge, acquired from learning a set of objects is only transferable to new objects that share properties with the old, then the recognition system’s optimal organization must be one containing specialized modules for different object classes. Our analysis starts from a premise we call the invariance hypothesis: that the computational goal of the ventral stream is to compute an invariant-to-transformations and discriminative signature for recognition. The key condition enabling approximate transfer of invariance without sacrificing discriminability turns out to be that the learned and novel objects transform similarly. This implies that the optimal recognition system must contain subsystems trained only with data from similarly-transforming objects and suggests a novel interpretation of domain-specific regions like the fusiform face area (FFA). Furthermore, we can define an index of transformation-compatibility, computable from videos, that can be combined with information about the statistics of natural vision to yield predictions for which object categories ought to have domain-specific regions in agreement with the available data. The result is a unifying account linking the large literature on view-based recognition with the wealth of experimental evidence concerning domain-specific regions.National Science Foundation (U.S.). Science and Technology Center (Award CCF-1231216)National Science Foundation (U.S.) (Grant NSF-0640097)National Science Foundation (U.S.) (Grant NSF-0827427)United States. Air Force Office of Scientific Research (Grant FA8650-05-C-7262)Eugene McDermott Foundatio

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.

Time Series of Magnetic Field Parameters of Merged MDI and HMI Space-Weather Active Region Patches as Potential Tool for Solar Flare Forecasting

Solar flare prediction studies have been recently conducted with the use of Space-Weather MDI (Michelson Doppler Imager onboard Solar and Heliospheric Observatory) Active Region Patches (SMARP) and Space-Weather HMI (Helioseismic and Magnetic Imager onboard Solar Dynamics Observatory) Active Region Patches (SHARP), which are two currently available data products containing magnetic field characteristics of solar active regions. The present work is an effort to combine them into one data product, and perform some initial statistical analyses in order to further expand their application in space weather forecasting. The combined data are derived by filtering, rescaling, and merging the SMARP with SHARP parameters, which can then be spatially reduced to create uniform multivariate time series. The resulting combined MDI-HMI dataset currently spans the period between April 4, 1996, and December 13, 2022, and may be extended to a more recent date. This provides an opportunity to correlate and compare it with other space weather time series, such as the daily solar flare index or the statistical properties of the soft X-ray flux measured by the Geostationary Operational Environmental Satellites (GOES). Time-lagged cross-correlation indicates that a relationship may exist, where some magnetic field properties of active regions lead the flare index in time. Applying the rolling window technique makes it possible to see how this leader-follower dynamic varies with time. Preliminary results indicate that areas of high correlation generally correspond to increased flare activity during the peak solar cycle