32 research outputs found

    Production of Sunflower Oil in Response to Nitrogen Fertilization under Semiarid Conditions under Irrigation

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    Sunflower is one of the most important oilseeds in the world, whose achenes are valued in several industrial chains, mainly for the extraction and processing of its oil. Although there is some information in the literature, the nitrogen (N) requirements for sunflower in semiarid conditions under irrigation are not yet clear. The experimental design used randomized blocks, with treatments in subdivided plots with four replications during two agricultural seasons. The N doses (e.g., 0, 30, 60, 90 and 120 kg ha-1) were assigned to the plots, and to the four sunflower cultivars used (e.g., AguarĂĄ 06, Altis 99, Multissol and BRS 122), which were planted in the subplots. The N doses for the maximum achene yields for the Multissol and BRS 122 cultivars were 81.8 and 86.6 kg ha-1, respectively, while N doses of 120 kg ha-1 produced the maximum achene yields for the Altis 99 and AguarĂĄ 06 cultivars in the 2016 crop season. In 2017, the Multissol and BRS 122 cultivars were given N doses of 100.7 and 92.8 kg ha-1, respectively, and the Altis 99 and AguarĂĄ 06 cultivars were each given an N dose of 120 kg ha-1 of N. The fertirrigated doses of maximum economic efficiency of N were 60 and 70 kg ha-1 for the Multissol and BRS 122 cultivars, respectively. For the oil yields, the maximum N doses of 78.0 and 86.7 kg ha-1 for the BRS 122 and AguarĂĄ 06 cultivars and for the Multissol and Altis 99 cultivars at an N dose of 120 kg ha-1 were used for the 2016 harvest. In 2017, the BRS 122 and Multissol cultivars received N doses of 88.6 and 99.1 kg ha-1, respectively, and the Altis 99 and AguarĂĄ 06 cultivars received N doses of 120 kg ha-1. The use of fertigation allowed greater efficiency for the N doses in the sunflower cultivars in the semiarid region

    Economic indicators of nitrogen fertilization in sunflower cultivars

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    Sunflower is one of the most important oilseeds in the world. However, cultivation in semi-arid regions requires analysis of production costs and profitability, ensuring effective decision-making, focused on farming procedures and techniques. In two agricultural crops, 2016 and 2017, experiments were conducted to evaluate the economic indicators of sunflower cultivars (‘Aguará 06’, ‘Altis 99’, ‘Multissol’ and ‘BRS 122’) submitted to nitrogen (N) doses (0; 30; 60; 90 and 120 kg ha-1) via fertirrigation under semi-arid conditions. The net margin corresponded to the increase of N doses, reaching a maximum net margin in the 2016 harvest of R366.89ha−1atthedoseof81kgha−1ofNfor‘BRS122’;R 366.89 ha-1 at the dose of 81 kg ha-1 of N for ‘BRS 122’; R 577.41 ha-1 with 118 kg ha-1 of N for ‘Multissol’; and for ‘Aguará 06’ (R2,124.00ha−1)and‘Altis99’(R 2,124.00 ha-1) and ‘Altis 99’ (R 976.66 ha-1) at the dose of 120 kg ha-1 of N. In the 2017 harvest, ‘BRS 122’ obtained R190.90ha−1inthedoseof83kgha−1ofNand‘Multissol’reachedR 190.90 ha-1 in the dose of 83 kg ha-1 of N and ‘Multissol’ reached R 657.50 in the dose of 85 kg ha-1 of N; the cultivars ‘Aguará 06’ (R1,078.00ha−1)and‘Altis99’(R 1,078.00 ha-1) and ‘Altis 99’ (R 957.14 ha-1) in the dose of 120 kg ha-1 of N. The rate of return and the profitability index were positive for all cultivars in both crops

    Agro-economic profitability of sweet potato cultivars as a function of the harvest age and times of cultivation in the semi-arid

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    The objective of this work was to evaluate the profitability of sweet potato cultivars, harvested at different ages and cultivated in different periods (rainy and dry) in the municipality of Mossoró, semi-arid region of Rio Grande do Norte. The experimental design was a randomized complete block design with four replications and treatments arranged in split plots scheme. The plots were composed of three sweet potato cultivars (ESAM 1, Paraná and Mother of Family) and the subplots for five harvest ages (90 , 105, 120, 135 and 150 days after transplanting - DAT). Productivity of commercial roots and production costs was evaluated, as well as the economic indicators: gross income, net income, rate of return and profit margin. Independently of the growing periods, the productivity of commercial roots increased with the later harvest of the crop and differentiated the cultivars. Production costs averaged R6,087.97ha−1intherainyseasonandR 6,087.97 ha-1 in the rainy season and R 6,181.42 ha-1 in the dry period. Labor expenditures were the most impacting of total expenditures. The cultivars ESAM 1 and Paraná presented higher productivities of commercial roots and profitability when cultivated in the rainy season, while Paraná cultivar was superior to the other cultivars in the crop in the dry season. In both growing periods, the harvest age of 150 DAT promoted higher productivities of commercial roots and profitability to sweet potato production

    Epidemiologic profile of juvenile-onset compared to adult-onset spondyloarthritis in a large Brazilian cohort

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    Objective To analyze the clinical and epidemiologic characteristics of juvenile-onset spondyloarthritis (SpA) (< 16 years) and compare them with a group of adult-onset (≄ 16 years) SpA patients. Patients and methods Prospective, observational and multicentric cohort with 1,424 patients with the diagnosis of SpA according to the European Spondyloarthropathy Study Group (ESSG) submitted to a common protocol of investigation and recruited in 29 reference centers participants of the Brazilian Registry of Spondyloarthritis (RBE – Registro Brasileiro de Espondiloartrites). Patients were divided in two groups: age at onset<16 years (JOSpA group) and age at onset ≄ 16 years (AOSpA group). Results Among the 1,424 patients, 235 presented disease onset before 16 years (16.5%). The clinical and epidemiologic variables associated with JOSpA were male gender (p<0.001), lower limb arthritis (p=0.001), enthesitis (p=0.008), anterior uveitis (p=0.041) and positive HLA-B27 (p=0.017), associated with lower scores of disease activity (Bath Ankylosing Spondylitis Disease Activity Index – BASDAI; p=0.007) and functionality (Bath Ankylosing Spondylitis Functional Index – BASFI; p=0.036). Cutaneous psoriasis (p<0.001), inflammatory bowel disease (p=0.023), dactylitis (p=0.024) and nail involvement (p=0.004) were more frequent in patients with adult-onset SpA. Conclusions Patients with JOSpA in this large Brazilian cohort were characterized predominantly by male gender, peripheral involvement (arthritis and enthesitis), positive HLA-B27 and lower disease scores.Objetivo Analisar as caracterĂ­sticas clĂ­nicas e epidemiolĂłgicas das espondiloartrites (EpA) de inĂ­cio juvenil (< 16 anos) e comparĂĄ-las com um grupo de pacientes com EspA de inĂ­cio na vida adulta (≄ 16 anos). Pacientes e mĂ©todos Coorte prospectiva, observacional e multicĂȘntrica com 1.424 pacientes com diagnĂłstico de EspA de acordo com o European Spondyloarthropathy Study Group (ESSG) submetidos a um protocolo comum de investigação e recrutados em 29 centros de referĂȘncia participantes do Registro Brasileiro de Espondiloartrites (RBE). Os pacientes foram divididos em dois grupos: idade no inĂ­cio<16 anos (grupo EspAiJ) e idade no inĂ­cio ≄ 16 anos. Resultados Entre os 1.424 pacientes, 235 manifestaram o inĂ­cio da doença antes dos 16 anos (16,5%). As variĂĄveis clĂ­nicas e epidemiolĂłgicas associadas com a EspAiJ foram: gĂȘnero masculino (p<0,001), artrite em membro inferior (p=0,001), entesite (p=0,008), uveĂ­te anterior (p=0,041) e HLA-B27 positivo (p=0,017), em associação com escores mais baixos de atividade da doença (Bath Ankylosing Spondylitis Disease Activity Index – BASDAI; p=0,007) e de capacidade funcional (Bath Ankylosing Spondylitis Functional Index – BASFI; p=0,036). A psorĂ­ase cutĂąnea (p<0,001), a doença inflamatĂłria intestinal (p=0,023), a dactilite (p=0,024) e o envolvimento ungueal (p=0,004) foram mais frequentes em pacientes com EspA de inĂ­cio na vida adulta. ConclusĂ”es Nessa grande coorte brasileira, os pacientes com EspAiJ se caracterizavam predominantemente pelo gĂȘnero masculino, envolvimento perifĂ©rico (artrite e entesite), HLA-B27 positivo e escores de doença mais baixos.Universidade Federal de PernambucoInsper Instituto de Educação e PesquisaUniversidade de SĂŁo Paulo Faculdade de Medicina DivisĂŁo de ReumatologiaUniversidade de BrasĂ­liaHospital Geral de GoiĂąniaUniversidade de CampinasUniversidade Federal do AmazonasPontifĂ­cia Universidade CatĂłlicaHospital EvangĂ©lico de CuritibaUniversidade Federal do Rio de JaneiroUniversidade Estadual do Rio de JaneiroFaculdade de Medicina de SĂŁo JosĂ© do Rio PretoUniversidade Federal do ParanĂĄHospital Geral de FortalezaSanta Casa do Rio de JaneiroSanta Casa de SĂŁo PauloHospital de Base do Distrito FederalUniversidade Federal do Mato Grosso do SulUniversidade Federal do Rio Grande do SulFaculdade de Medicina Souza MarquesHospital do Servidor PĂșblico EstadualUniversidade de SĂŁo Paulo Instituto de Ortopedia e TraumatologiaUniversidade Federal de Santa CatarinaUniversidade Federal de SĂŁo Paulo (UNIFESP)Santa Casa de Belo HorizonteUniversidade Federal de Minas GeraisUniversidade Federal do CearĂĄEscola de Medicina e SaĂșde PĂșblicaUniversidade Federal do ParĂĄUniversidade Federal do EspĂ­rito SantoUNIFESPSciEL

    Erratum of Enteropathic arthritis in Brazil: data from the Brazilian registry of spondyloarthritis

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    Universidade Federal de Minas GeraisInstituto Insper de Educação e PesquisaUniversidade de SĂŁo Paulo Disciplina de ReumatologiaUniversidade de BrasĂ­liaHospital Geral de GoiĂąniaUniversidade de CampinasUniversidade Federal do AmazonasPontifĂ­cia Universidade CatĂłlicaFaculdade de Medicina de SĂŁo JosĂ© do Rio PretoHospital EvangĂ©lico de CuritibaUniversidade Federal do Rio de JaneiroUniversidade Federal do ParanĂĄHospital Geral de FortalezaUniversidade Estadual do Rio de JaneiroSanta Casa do Rio de JaneiroSanta Casa de SĂŁo PauloHospital de BaseUniversidade Federal do Mato Grosso do SulUniversidade Federal de PernambucoUniversidade Federal do Rio Grande do SulFaculdade de Medicina Souza MarquesHospital do Servidor PĂșblico EstadualUniversidade de SĂŁo Paulo Instituto de Ortopedia e TraumatologiaUniversidade Federal de Santa CatarinaUniversidade Federal de SĂŁo Paulo (UNIFESP)Santa Casa de Belo HorizonteUniversidade Federal do CearĂĄEscola de Medicina e SaĂșde PĂșblicaUniversidade Federal do ParĂĄUniversidade Federal do EspĂ­rito SantoUNIFESPSciEL

    Enteropathic arthritis in Brazil: data from the brazilian registry of spondyloarthritis

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    Inflammatory bowel diseases (Crohn's disease and ulcerative rectocolitis) have extraintestinal manifestations 25% of the patients, with the most common one being the enteropathic arthritis. METHODS: Prospective, observational, multicenter study with patients from 29 reference centers participating in the Brazilian Registry of Spondyloarthritis (RBE), which incorporates the RESPONDIA (Ibero-American Registry of Spondyloarthritis) group. Demographic and clinical data were collected from 1472 patients and standardized questionnaires for the assessment of axial mobility, quality of life, enthesitic involvement, disease activity and functional capacity were applied. Laboratory and radiographic examinations were performed. The aim of this study is to compare the clinical, epidemiological, genetic, imaging, treatment and prognosis characteristics of patients with enteropathic arthritis with other types of spondyloarthritis in a large Brazilian cohort. RESULTS: A total of 3.2% of patients were classified as having enteroarthritis, 2.5% had spondylitis and 0.7%, arthritis (peripheral predominance). The subgroup of individuals with enteroarthritis had a higher prevalence in women (P < 0.001), lower incidence of inflammatory axial pain (P < 0.001) and enthesitis (P = 0.004). HLA-B27 was less frequent in the group with enteroarthritis (P = 0.001), even when considering only those with the pure axial form. There was a lower prevalence of radiographic sacroiliitis (P = 0.009) and lower radiographic score (BASRI) (P = 0.006) when compared to patients with other types of spondyloarthritis. They also used more corticosteroids (P < 0.001) and sulfasalazine (P < 0.001) and less non-steroidal anti-inflammatory drugs (P < 0.001) and methotrexate (P = 0.001). CONCLUSION: There were differences between patients with enteroarthritis and other types of spondyloarthritis, especially higher prevalence of females, lower frequency of HLA-B27, associated with less severe axial involvement.As doenças inflamatĂłrias intestinais (doença de Crohn e retocolite ulcerativa) apresentam manifestaçÔes extraintestinais em um quarto dos pacientes, sendo a mais comum a artrite enteropĂĄtica. MÉTODOS: Estudo prospectivo, observacional e multicĂȘntrico, realizado com pacientes de 29 centros de referĂȘncia participantes do Registro Brasileiro de Espondiloartrites (RBE), que se incorpora ao grupo RESPONDIA (Registro Ibero-americano de Espondiloartrites). Dados demogrĂĄficos e clĂ­nicos de 1472 pacientes foram colhidos, e aplicaram-se questionĂĄrios padronizados de avaliação de mobilidade axial, de qualidade de vida, de envolvimento entesĂ­tico, de atividade de doença e de capacidade funcional. Exames laboratoriais e radiogrĂĄficos foram realizados. Objetivamos, neste presente artigo, comparar as caracterĂ­sticas clĂ­nicas, epidemiolĂłgicas, genĂ©ticas, imagenolĂłgicas, de tratamento e prognĂłstico de enteroartrĂ­ticos com os outros espondiloartrĂ­ticos nesta grande coorte brasileira. RESULTADOS: Foram classificados como enteroartrite 3,2% dos pacientes, sendo que 2,5% tinham espondilite e 0,7%, artrite (predomĂ­nio perifĂ©rico). O subgrupo de indivĂ­duos com enteroartrite apresentava maior prevalĂȘncia de mulheres (P < 0,001), menor incidĂȘncia de dor axial inflamatĂłria (P < 0,001) e de entesite (P = 0,004). O HLA-B27 foi menos frequente no grupo de enteroartrĂ­ticos (P = 0,001), mesmo se considerado apenas aqueles com a forma axial pura. Houve menor prevalĂȘncia de sacroiliĂ­te radiolĂłgica (P = 0,009) e tambĂ©m menor escore radiogrĂĄfico (BASRI) (P = 0,006) quando comparado aos pacientes com as demais espondiloartrites. TambĂ©m fizeram mais uso de corticosteroides (P < 0,001) e sulfassalasina (P < 0,001) e menor uso de anti-inflamatĂłrios nĂŁo hormonais (P < 0,001) e metotrexato (P = 0,001). CONCLUSÃO: Foram encontradas diferenças entre as enteroartrites e as demais espondiloartrites, principalmente maior prevalĂȘncia do sexo feminino, menor frequĂȘncia do HLA-B27, associados a uma menor gravidade do acometimento axial.Universidade Federal de Minas GeraisInstituto Insper de Educação e PesquisaUniversidade de SĂŁo PauloUniversidade de BrasĂ­liaHospital Geral de GoiĂąniaUniversidade de CampinasUniversidade Federal do AmazonasPontifĂ­cia Universidade CatĂłlicaFaculdade de Medicina de SĂŁo JosĂ© do Rio PretoHospital EvangĂ©lico de CuritibaUniversidade Federal do Rio de JaneiroUniversidade Federal do ParanĂĄHospital Geral de FortalezaUniversidade Estadual do Rio de JaneiroSanta Casa do Rio de JaneiroSanta Casa de SĂŁo PauloHospital de BaseUniversidade Federal do Mato Grosso do SulUniversidade Federal de PernambucoUniversidade Federal do Rio Grande do SulFaculdade de Medicina Souza MarquesHospital do Servidor PĂșblico EstadualUniversidade de SĂŁo Paulo Instituto de Ortopedia e TraumatologiaUniversidade Federal de Santa CatarinaUniversidade Federal de SĂŁo Paulo (UNIFESP)Santa Casa de Belo HorizonteUniversidade Federal do CearĂĄEscola de Medicina e SaĂșde PĂșblicaUniversidade Federal do ParĂĄUniversidade Federal do EspĂ­rito SantoUNIFESPSciEL

    O perfil semiolĂłgico do paciente portador de hemorragia digestiva alta

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    OBJETIVO: O seguinte estudo objetivou descrever a semiologia do paciente portador de hemorragia digestiva alta, considerando como determinante na avaliação de potencias focos hemorrĂĄgicos. METODOLOGIA: Foram realizadas buscas nas plataformas do SciELO, LILACS, PubMed, Scopus e Google Scholar,utilizando os descritores gastrointestinal bleeding, peptic ulcerous disease e varicose hemorrhage, sendo identificados 35 estudos, dos quais foram incluĂ­dos 13 artigos completos. Desses estudos, 5 avaliaram as principais etiologias, 2 o surgimento de novos testes diagnĂłsticos, 2 analisaram os aspectos epidemiolĂłgicos e 1 a sintomatologia apresentada pelo acometimento da hemorragia digestiva alta. Observou-se inicialmente a abundĂąncias de informaçÔes conceituais sobre o sangramento, como um transtorno clĂ­nico comum, acompanhada de inĂșmeras manifestaçÔes, considerando que o foco hemorrĂĄgico pode ocorrer em qualquer porção do trato gastrointestinal. Neste estudo, todas as publicaçÔes eleitas apresentaram o quadro semiolĂłgico composto por algia abdominal, indĂ­cios de choque hipovolĂȘmico e taquicardia, alguns exibiram quedas abruptas da pressĂŁo arterial, odinofagia, ĂȘmese, nĂĄuseas e estado ictĂ©rico. Os pacientes implicados, cronicamente, jĂĄ manifestaram ocorrĂȘncias prĂ©vias, devido ao carĂĄter recidivante torna-se essencial investigar a existĂȘncia de varizes, fĂ­stula aorto-entĂ©rica, angiodisplasia e doença ulcerosa. CONCLUSÃO: Elucida-se que a hemorragia digestiva alta representa a principal causa de sangramento do trato gastrointestinal, majoritamente manifesta-se como hematĂȘmese ou melena e cursam com o quadro sintomatolĂłgico que auxilia na avaliação da gravidade deste e o embasamento de potenciais focos de sangramento e que contribuam para disseminação de informaçÔes e intervençÔes futuras

    O embaixador; o livreiro e o policial circulação de livros proibidos e medo revolucionårio em Portugal na virada do século XVIII para o XIX

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    CatĂĄlogo TaxonĂŽmico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

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    The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the CatĂĄlogo TaxonĂŽmico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

    Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

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    Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≄ II, EF ≀35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure &lt; 100 mmHg (n = 1127), estimated glomerular filtration rate &lt; 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation
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