17 research outputs found

    Lithologic and electrometric characteristic of productive layers of the gurarinckiy-sobolinniy deposit low-chalky adjourments

    Get PDF
    The construction of abnormal geochemical fields accompanying gold mineralization is investigated; criteria of its quantitative estimation are developed. Orderliness estimation methods of geochemical field abnormal structures and intensity of hydrothermal process are offered. Dependence between quantitative parameters of these structures and scales of gold mineralization is established. Estimation possibility of deposits and ore fields erosive section by parameter values of abnormal geochemical fields is shown

    SCAview: an Intuitive Visual Approach to the Integrative Analysis of Clinical Data in Spinocerebellar Ataxias

    Get PDF
    With SCAview, we present a prompt and comprehensive tool that enables scientists to browse large datasets of the most common spinocerebellar ataxias intuitively and without technical effort. Basic concept is a visualization of data, with a graphical handling and filtering to select and define subgroups and their comparison. Several plot types to visualize all data points resulting from the selected attributes are provided. The underlying synthetic cohort is based on clinical data from five different European and US longitudinal multicenter cohorts in spinocerebellar ataxia type 1, 2, 3, and 6 (SCA1, 2, 3, and 6) comprising > 1400 patients with overall > 5500 visits. First, we developed a common data model to integrate the clinical, demographic, and characterizing data of each source cohort. Second, the available datasets from each cohort were mapped onto the data model. Third, we created a synthetic cohort based on the cleaned dataset. With SCAview, we demonstrate the feasibility of mapping cohort data from different sources onto a common data model. The resulting browser-based visualization tool with a thoroughly graphical handling of the data offers researchers the unique possibility to visualize relationships and distributions of clinical data, to define subgroups and to further investigate them without any technical effort. Access to SCAview can be requested via the Ataxia Global Initiative and is free of charge

    Neurological perspectives on voltage-gated sodium channels

    Get PDF
    corecore