Chaotic scattering with direct processes: A generalization of Poisson's kernel for non-unitary scattering matrices

The problem of chaotic scattering in presence of direct processes or prompt responses is mapped via a transformation to the case of scattering in absence of such processes for non-unitary scattering matrices, \tilde S. In the absence of prompt responses, \tilde S is uniformly distributed according to its invariant measure in the space of \tilde S matrices with zero average, < \tilde S > =0. In the presence of direct processes, the distribution of \tilde S is non-uniform and it is characterized by the average (\neq 0). In contrast to the case of unitary matrices S, where the invariant measures of S for chaotic scattering with and without direct processes are related through the well known Poisson kernel, here we show that for non-unitary scattering matrices the invariant measures are related by the Poisson kernel squared. Our results are relevant to situations where flux conservation is not satisfied. For example, transport experiments in chaotic systems, where gains or losses are present, like microwave chaotic cavities or graphs, and acoustic or elastic resonators.Comment: Added two appendices and references. Corrected typo

Caracterización química de la Fibra de Coco (Cocus nucifera L.) de México utilizando Espectroscopía de Infrarrojo (FTIR)

There is a growing interest in products with less environmental impact, this makes the use of natural fibers a viable alternative. The use of materials of biological origin is increasing in an attempt to reduce the amount of thermoplastic polymers from non-renewable sources. In this framework, the work characterizes the chemical characterization of coconut fiber (Cocus nucifera L.), by means of infrared spectroscopy (FTIR), and the spectra of the fibers of coconut, from two important growing sites, the Acapulco and San Jerónimo de Juárez regions, in the state of Guerrero, Mexico, the results obtained are compared with other spectra of other natural fibers, due to the high content of lignin, properties are attributed viscoelastic, by which it is inferred that when the fibers are subjected to a compression load or an impact force, the amorphous region (lignin) functions as a buffer and is resilient to the applied phenomena, a desirable characteristic in packaging materials, this proves that the coconut fiber with natural binder, could be a proposal to be used as packing material in packaging, the data corroborate a high percentage of cellulose and lignin present in the samples studied.Existe un creciente interés en productos con menor impacto ambiental, esto hace que el uso de fibras naturales sea una alternativa viable. El uso de materiales de origen biológico está aumentando en un intento de reducir la cantidad de polímeros termoplásticos de fuentes no renovables. En este marco se presenta el trabajo caracterización química de la fibra de coco (Cocus nucifera L.), mediante espectroscopía de infrarrojo (FTIR) , y se muestran los espectros de las fibras de coco, de dos lugares de cultivo importantes, la región de Acapulco y San Jerónimo de Juárez, en el estado de Guerrero, México , los resultados obtenidos son comparados con otros espectros de otras fibras naturales, debido al alto contenido de lignina se le atribuyen propiedades viscoelásticas, por lo que se infiere que al ser sometidas las fibras a una carga de compresión o una fuerza de impacto, la región amorfa (lignina) funciona como amortiguador y es resiliente a los fenómenos aplicados, una característica deseable en los materiales de embalaje, esto prueba que la fibra de coco con aglomerante natural, pudiera ser una propuesta para usarse como material de relleno en embalajes, los datos corroboran un alto porcentaje de celulosa y lignina presenteen las muestras estudiadas

Applications of Direct Injection Soft Chemical Ionisation-Mass Spectrometry for the Detection of Pre-blast Smokeless Powder Organic Additives

Analysis of smokeless powders is of interest from forensics and security perspectives. This article reports the detection of smokeless powder organic additives (in their pre-detonation condition), namely the stabiliser diphenylamine and its derivatives 2-nitrodiphenylamine and 4-nitrodiphenylamine, and the additives (used both as stabilisers and plasticisers) methyl centralite and ethyl centralite, by means of swab sampling followed by thermal desorption and direct injection soft chemical ionisation-mass spectrometry. Investigations on the product ions resulting from the reactions of the reagent ions H3O+ and O2+ with additives as a function of reduced electric field are reported. The method was comprehensively evaluated in terms of linearity, sensitivity and precision. For H3O+, the limits of detection (LoD) are in the range of 41-88 pg of additive, for which the accuracy varied between 1.5 and 3.2%, precision varied between 3.7 and 7.3% and linearity showed R20.9991. For O2+, LoD are in the range of 72 to 1.4 ng, with an accuracy of between 2.8 and 4.9% and a precision between 4.5 and 8.6% and R20.9914. The validated methodology was applied to the analysis of commercial pre-blast gun powders from different manufacturers.(VLID)4826148Accepted versio

Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans.

Here we studied HLA blocks and haplotypes in a group of 218 Lacandon Maya Native American using a high-resolution next generation sequencing (NGS) method. We assessed the genetic diversity of HLA class I and class II in this population, and determined the most probable ancestry of Lacandon Maya HLA class I and class II haplotypes. Importantly, this Native American group showed a high degree of both HLA homozygosity and linkage disequilibrium across the HLA region and also lower class II HLA allelic diversity than most previously reported populations (including other Native American groups). Distinctive alleles present in the Lacandon population include HLA-A*24:14 and HLA-B*40:08. Furthermore, in Lacandons we observed a high frequency of haplotypes containing the allele HLA-DRB1*04:11, a relatively frequent allele in comparison with other neighboring indigenous groups. The specific demographic history of the Lacandon population including inbreeding, as well as pathogen selection, may have elevated the frequencies of a small number of HLA class II alleles and DNA blocks. To assess the possible role of different selective pressures in determining Native American HLA diversity, we evaluated the relationship between genetic diversity at HLA-A, HLA-B and HLA-DRB1 and pathogen richness for a global dataset and for Native American populations alone. In keeping with previous studies of such relationships we included distance from Africa as a covariate. After correction for multiple comparisons we did not find any significant relationship between pathogen diversity and HLA genetic diversity (as measured by polymorphism information content) in either our global dataset or the Native American subset of the dataset. We found the expected negative relationship between genetic diversity and distance from Africa in the global dataset, but no relationship between HLA genetic diversity and distance from Africa when Native American populations were considered alone

The lack of the TetR-like repressor gene BCG_2177c (Rv2160A) may help mycobacteria overcome intracellular redox stress and survive longer inside macrophages when surrounded by a lipid environment

Mycobacteria, like other microorganisms, survive under different environmental variations by expressing an efficient adaptive response, oriented by regulatory elements, such as transcriptional repressors of the TetR family. These repressors in mycobacteria also appear to be related to cholesterol metabolism. In this study, we have evaluated the effect of a fatty acid (oleic–palmitic–stearic)/cholesterol mixture on some phenotypic and genotypic characteristics of a tetR-mutant strain (BCG_2177c mutated gene) of M. bovis BCG, a homologous of Rv2160A of M. tuberculosis. In order to accomplish this, we have analyzed the global gene expression of this strain by RNA-seq and evaluated its neutral-lipid storage capacity and potential to infect macrophages. We have also determined the macrophage response by measuring some pro- and anti-inflammatory cytokine expressions. In comparison with wild-type microorganisms, we showed that the mutation in the BCG_2177c gene did not affect the growth of M. bovis BCG in the presence of lipids but it probably modified the structure/composition of its cell envelope. Compared to with dextrose, an overexpression of the transcriptome of the wild-type and mutant strains was observed when these mycobacteria were cultured in lipids, mainly at the exponential phase. Twelve putative intracellular redox balance maintenance genes and four others coding for putative transcriptional factors (including WhiB6 and three TetR-like) were the main elements repeatedly overexpressed when cultured in the presence of lipids. These genes belonged to the central part of what we called the “genetic lipid signature” for M. bovis BCG. We have also found that all these mycobacteria genotypic changes affected the outcome of BCG-infected macrophages, being the mutant strain most adapted to persist longer inside the host. This high persistence result was also confirmed when mutant-infected macrophages showed overexpression of the anti-inflammatory cytokine TGF-ß versus pro-inflammatory cytokines. In summary, the lack of this TetR-like repressor expression, within a lipid environment, may help mycobacteria overcome intracellular redox stress and survive longer inside their host

Factors of the epidemiological triad that influence the persistence of human papilloma virus infection in women with systemic lupus erythematosus

We studied the epidemiologic triad-related factors influencing human papilloma virus (HPV) persistence in Mexican women with systemic lupus erythematosus (SLE). Patients aged ?18 years with SLE (American College of Rheumatology criteria), with and without HPV persistence, were selected. Groups were analyzed by (1) host: clinical disease characteristics; (2) agent: (I) infectious (prevalence, incidence, HPV genotype and co-infections (?2 HPV genotypes or mycoplasmas)), (II) chemical (contraceptives and immunosuppressive drugs) and (III) physical (vitamin D deficiency) and (3) environment. A total of 121 SLE patients were selected over a two-year period. (1) Host: mean age 45.8 years and disease duration 12.7 years. (2) Agent: (I) infectious. HPV infection prevalence in the second sample was 26.4%, high-risk HPV genotypes 21.5% and co-infections 7.4%. HPV infection incidence was 13.2%, persistence 13.2% and clearance 15.7%. (II) Chemical: use of oral hormonal contraceptives 5% and immunosuppressive treatment 97.5%. (III) Physical: Vitamin D levels were similar in both groups. (3) Environment: (I) natural. A total of 60.6% of patients were residents of Puebla City. (II) Social: The mean education level was 10.9. Poverty levels were: III degree 52.4%, IV degree 28% and II degree 17%. (III) Cultural behavioral: Onset of sexual life was 20.5 years, 10% had ?3 sexual partners and 51.2% were postmenopausal. In conclusion, no factor of the epidemiologic triad was associated with HPV infection prevalence. © The Author(s) 2018

Outer-disk reddening and gas-phase metallicities: The CALIFA connection

Astronomy and Astrophysics 585 (2016): A47 reproduced with permission from Astronomy & AstrophysicsWe study, for the first time in a statistically significant and well-defined sample, the relation between the outer-disk ionized-gas metallicity gradients and the presence of breaks in the surface brightness profiles of disk galaxies. Sloan Digital Sky Survey (SDSS) g′- and r′-band surface brightness, (g′ - r′) color, and ionized-gas oxygen abundance profiles for 324 galaxies within the Calar Alto Legacy Integral Field Area (CALIFA) survey are used for this purpose. We perform a detailed light-profile classification, finding that 84% of our disks show down- or up-bending profiles (Type II and Type III, respectively), while the remaining 16% are well fitted by one single exponential (Type I). The analysis of the color gradients at both sides of this break shows a U-shaped profile for most Type II galaxies with an average minimum (g′ - r′) color of ∼ 0.5mag and an ionized-gas metallicity flattening associated with it only in the case of low-mass galaxies. Comparatively, more massive systems show a rather uniform negative metallicity gradient. The correlation between metallicity flattening and stellar mass for these systems results in p-values as low as 0.01. Independent of the mechanism having shaped the outer light profiles of these galaxies, stellar migration or a previous episode of star formation in a shrinking star-forming disk, it is clear that the imprint in their ionized-gas metallicity was different for low- and high-mass Type II galaxies. In the case of Type III disks, a positive correlation between the change in color and abundance gradient is found (the null hypothesis is ruled out with a p-value of 0.02), with the outer disks of Type III galaxies with masses ≤1010 M′ showing a weak color reddening or even a bluing. This is interpreted as primarily due to a mass downsizing effect on the population of Type III galaxies that recently experienced an enhanced inside-out growthWe acknowledge support from the Plan Nacional de Investigación y Desarrollo funding programs, AyA2010-15081, AyA2012-30717 and AyA2013-46724P, of Spanish Ministerio de Economía y Competitividad (MINECO). A.G.d.P. acknowledges the support from the FP7 Marie Curie Actions of the European Commission, via the Initial Training Network DAGAL under REA grant agreement PITNGA- 2011-289313. C.C.-T. thanks the support of the Spanish Ministerio de Educación, Cultura y Deporte by means of the FPU fellowship program. C.J.W. acknowledges support through the Marie Curie Career Integration Grant 303912. Support for L.G. is provided by the Ministry of Economy, Development, and Tourism’s Millennium Science Initiative through grant IC 120009, awarded to The Millennium Institute of Astrophysics, MAS. L.G. acknowledges support by CONIC YT through FONDECYT grant 3140566. S.F.S. thanks the CONACYT-125180 and DGAPA-IA100815 projects for providing him support in this study. J.M.A. acknowledges support from the European Research Council Starting Grant (SEDmorph; P.I. V. Wild). P.P. is supported by FCT through the Investigador FCT Contract No. IF/01220/2013 and POPH/FSE (EC) by FEDER funding through the program COMPETE. He also acknowledges support by FCT under project FCOMP-01-0124-FEDER-029170 (Reference FCT PTDC/FISAST/ 3214/2012), funded by FCT-MEC (PIDDAC) and FEDER (COMPETE