Oscillations in β Ursae Minoris

Aims. From observations of the K4III star β UMi we attempt to determine whether oscillations or any other form of variability is present. Methods. A high-quality photometric time series of ≈1000 days in length obtained from the SMEI instrument on the Coriolis satellite is analysed. Various statistical tests were performed to determine the significance of features seen in the power density spectrum of the light curve. Results. Two oscillations with frequencies 2.44 and 2.92 μHz have been identified. We interpret these oscillations as consecutive overtones of an acoustic spectrum, implying a large frequency spacing of 0.48 μHz. Using derived asteroseismic parameters in combination with known astrophysical parameters, we estimate the mass of β UMi to be 1.3 ± 0.3 M. Peaks of the oscillations in the power density spectrum show width, implying that modes are stochastically excited and damped by convection. The mode lifetime is estimated at 18 ± 9 days

Plato's five-fold classifications in relation to the metaphysics of the middle-Platonists

The Parmenides shows Plato's concern to relate the various branches of reality which he had earlier discerned; modifying the ontology of Republic VI, he sought to combine four worlds into one in the third of five positive hypotheses. The Sophist then attempts to show that reality is five; the five components are echoed in the "Psychogony" of the Timaeus, in which work Plato is confronted with a choice between one world and five. Two cryptic classifications from the Philebus suggest Plato’s continued interest in the number, and the Epinomis and Seventh Letter show that the Academy knew of this. Speusippus, depending heavily on the Parmenides, adopted a system of five separate "existences", each with their own first-principles. Xenocrates, though favouring tripartitions, preserved a framework in which the five-fold concept of the whole became understandable. Academic scepticism made it necessary for Posidonlus and Antiochus to look back to the works of Xenocrates for guidance, from whom they received an Old-Academic understanding of the Master and new interest in Speusippus. Through this latter Pythagoreans learned to interpret the Parmenides; through him also Theodorus learned to misinterpret the Timacus, The Philebus grew in importance, the final classification being authoritative for Arius, Plutarch, and Albinus. Seneca attributes five causes to Plato, Plutarch regards the number as of supreme philosophical importance, Albinus' writings echo this view. Theon, Maximus, and Numenius conform in different ways with a tradition that respects a five-fold metaphysic

Asteroseismology of red giants: photometric observations of Arcturus by SMEI

We present new results on oscillations of the K1.5 III giant Arcturus (alpha Boo), from analysis of just over 2.5 yr of precise photometric observations made by the Solar Mass Ejection Imager (SMEI) on board the Coriolis satellite. A strong mode of oscillation is uncovered by the analysis, having frequency 3.51+/-0.03 micro-Hertz. By fitting its mode peak, we are able offer a highly constrained direct estimate of the damping time (tau = 24+/-1 days). The data also hint at the possible presence of several radial-mode overtones, and maybe some non-radial modes. We are also able to measure the properties of the granulation on the star, with the characteristic timescale for the granulation estimated to be 0.50+/-0.05 days.Comment: 6 pages, 5 figures; accepted for publication in MNRAS Letter

SMEI observations of previously unseen pulsation frequencies in γ Doradus

Aims. As g-mode pulsators, gamma-Doradus-class stars may naïvely be expected to show a large number of modes. Taking advantage of the long photometric time-series generated by the solar mass ejection imager (SMEI) instrument, we have studied the star gamma Doradus to determine whether any other modes than the three already known are present at observable amplitude. Methods. High-precision photometric data from SMEI taken between April 2003 and March 2006 were subjected to periodogram analysis with the PERIOD04 package. Results. We confidently determine three additional frequencies at 1.39, 1.87, and 2.743 d−1. These are above and beyond the known frequencies of 1.320, 1.364, and 1.47 d−1. Conclusions. Two of the new frequencies, at 1.39 and 1.87 d−1, are speculated to be additional modes of oscillation, with the third frequency at 2.743−1 a possible combination frequency

Opportunities for system level improvement in antibiotic use across the surgical pathway

Optimizing antibiotic prescribing across the surgical pathway (before, during, and after surgery) is a key aspect of tackling important drivers of antimicrobial resistance and simultaneously decreasing the burden of infection at the global level. In the UK alone, 10 million patients undergo surgery every year, which is equivalent to 60% of the annual hospital admissions having a surgical intervention. The overwhelming majority of surgical procedures require effectively limited delivery of antibiotic prophylaxis to prevent infections. Evidence from around the world indicates that antibiotics for surgical prophylaxis are administered ineffectively, or are extended for an inappropriate duration of time postoperatively. Ineffective antibiotic prophylaxis can contribute to the development of surgical site infections (SSIs), which represent a significant global burden of disease. The World Health Organization estimates SSI rates of up to 50% in postoperative surgical patients (depending on the type of surgery), with a particular problem in low- and middle-income countries, where SSIs are the most frequently reported healthcare-associated infections. Across European hospitals, SSIs alone comprise 19.6% of all healthcare-acquired infections. Much of the scientific research in infection management in surgery is related to infection prevention and control in the operating room, surgical prophylaxis, and the management of SSIs, with many studies focusing on infection within the 30-day postoperative period. However it is important to note that SSIs represent only one of the many types of infection that can occur postoperatively. This article provides an overview of the surgical pathway and considers infection management and antibiotic prescribing at each step of the pathway. The aim was to identify the implications for research and opportunities for system improvement

Developing the 'gripes' tool for junior doctors to report concerns:a pilot study

Background Junior doctors often have concerns about quality and safety but show low levels of engagement with incident reporting systems. We aimed to develop and pilot a web-based reporting tool for junior doctors to proactively report concerns about quality and safety of care, and optimise it for future use. Methods We developed the gripes tool with input from junior doctors and piloted it at a large UK teaching hospital trust. We evaluated the tool through an analysis of concerns reported over a 3-month pilot period, and through interviews with five stakeholders and two focus groups with medical students and junior doctors about their views of the tool. Results Junior doctors reported 111 concerns during piloting, including a number of problems previously unknown to the trust. Junior doctors felt the tool was easy to use and encouraged them to report. Barriers to engagement included lack of motivation of junior doctors to report concerns, and fear of repercussions. Ensuring transparency about who would see reported concerns, and providing feedback across whole cohorts of junior doctors about concerns raised and how these had been addressed to improve patient safety at the trust, were seen having the potential to mitigate against these barriers. Sustainability of the tool was seen as requiring a revised model of staffing to share the load for responding to concerns and ongoing efforts to integrate the tool and data with other local systems for gathering intelligence about risks and incidents. Following piloting the trust committed to continuing to operate the gripes tool on an ongoing basis. Conclusions The gripes tool has the potential to enable trusts to proactively monitor and address risks to patient safety, but sustainability is likely to be dependent on organisational commitment to staffing the system and perceptions of added value over the longer term

Alcohol consumption among university students in the night-time economy in the UK: A three-wave longitudinal study

This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this recordBackground. Excessive alcohol consumption is commonly reported in university/college students, and contributes to emerging peer-group relations. Purpose. This study aimed to provide up-to-date longitudinal data on students’ alcohol consumption patterns, and predictors of this, across a single academic year. Methods. A 3-wave study was conducted at a university in the UK. Participants reported their alcohol consumption patterns, along with perceptions of the social norms and behavioral expectations associated with attending licensed venues where alcohol is sold (the “night time economy”). Participants also reported their social identification with this environment. Results. Around half of participants overall fell into the three higher alcohol-risk categories (moderate, high or hazardous drinking). A modest reduction in consumption was observed across the study. At each assessment point, males reported greater alcohol consumption in the preceding two months than females, while Year 4 students and those on graduate-entry programs reported the lowest consumption. Excessive alcohol consumption was regarded as largely normative within the night time economy, both descriptively (“what others do”) and injunctively (“what others approve of”). Social identification and norm perceptions, along with gender, year group, and intoxication and socialising expectations, were significantly associated with higher alcohol consumption at baseline. However, baseline consumption was the only variable significantly associated with alcohol use at the end of the academic year. Conclusions. Many students drink alcohol at potentially harmful levels, and norms and expectations supporting this consumption are prominent and stable. The findings support a targeted approach to intervention that accounts for heterogeneity in the student population.Drinkaware TrustNational Institute for Health Research (NIHR

Can raising awareness about the psychological causes of obesity reduce obesity stigma?

Obesity stigma largely remains a socially acceptable bias with harmful outcomes for its victims. While many accounts have been put forward to explain the bias, the role of obesity etiology beliefs has received little scrutiny. The research examined the effect that beliefs about the psychological etiology of obesity have on the expression of obesity stigma and the mechanisms underpinning this effect. Participants (N = 463) were asked to evaluate a target person with obesity after reading one of three possible etiologies: psychological, genetic, or behavioral. The presentation of a psychological etiology of obesity elicited less prejudice compared to behavioral causes but greater prejudice compared to genetic causes; observed differences were found to be a function of the agency ascribed to the target’s obesity and empathy expressed for the target. The findings highlight the impact that communicating obesity in terms of psychological causes can have for the expression of obesity stigma

Implementation research for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva infection prevention and control (IPC)-think tank (part 1)

Background Around 5–15% of all hospital patients worldwide suffer from healthcare-associated infections (HAIs), and years of excessive antimicrobial use in human and animal medicine have created emerging antimicrobial resistance (AMR). A considerable amount of evidence-based measures have been published to address these challenges, but the largest challenge seems to be their implementation. Methods In June 2017, a total of 42 experts convened at the Geneva IPC-Think Tank to discuss four domains in implementation science: 1) teaching implementation skills; 2) fostering implementation of IPC and antimicrobial stewardship (AMS) by policy making; 3) national/international actions to foster implementation skills; and 4) translational research bridging social sciences and clinical research in infection prevention and control (IPC) and AMR. Results Although neglected in the past, implementation skills have become a priority in IPC and AMS. They should now be part of any curriculum in health care, and IPC career paths should be created. Guidelines and policies should be aligned with each other and evidence-based, each document providing a section on implementing elements of IPC and AMS in patient care. International organisations should be advocates for IPC and AMS, framing them as patient safety issues and emphasizing the importance of implementation skills. Healthcare authorities at the national level should adopt a similar approach and provide legal frameworks, guidelines, and resources to allow better implementation of patient safety measures in IPC and AMS. Rather than repeating effectiveness studies in every setting, we should invest in methods to improve the implementation of evidence-based measures in different healthcare contexts. For this, we need to encourage and financially support collaborations between social sciences and clinical IPC research. Conclusions Experts of the 2017 Geneva Think Tank on IPC and AMS, CDC, and WHO agreed that sustained efforts on implementation of IPC and AMS strategies are required at international, country, and hospital management levels, to provide an adequate multimodal framework that addresses (not exclusively) leadership, resources, education and training for implementing IPC and AMS. Future strategies can build on this agreement to make strategies on IPC and AMS more effective