3,377 research outputs found
Effects of state dependent correlations on nucleon density and momentum distributions
The proton momentum and density distributions of closed shell nuclei are
calculated within a model treating short--range correlations up to first order
in the cluster expansion. The validity of the model is verified by comparing
the results obtained with purely scalar correlations with those produced by
finite nuclei Fermi Hypernetted Chain calculations. State dependent
correlations are used to calculate momentum and density distributions of 12C,
16O, 40Ca, and 48Ca, and the effects of their tensor components are studied.Comment: 16 pages, latex, 8 figures, accepted for publication in Phys. Rev.
Two-nucleon emission in the longitudinal response
The contribution of the two-nucleon emission in the longitudinal response for
inclusive electron scattering reactions is studied. The model adopted to
perform the calculations is based upon Correlated Basis Function theory but it
considers only first order terms in the correlation function. The proper
normalization of the wave function is ensured by considering, in addition to
the usually evaluated two-point diagrams, also the three-point diagrams.
Results for the 12C nucleus in the quasi-elastic region are presented.Comment: 7 pages, 4 Postscript figure
Mean-field calculations of quasi-elastic responses in 4He
We present calculations of the quasi-elastic responses functions in 4He based
upon a mean-field model used to perform analogous calculations in heavier
nuclei. The meson exchange current contribution is small if compared with the
results of calculations where short-range correlations are explicitly
considered. It is argued that the presence of these correlations in the
description of the nuclear wave functions is crucial to make meson exchange
current effects appreciable.Comment: uuencoded file containing 7 LaTex peges plus 3 ps figures. To be
published in Physical Review
Analysis of exchange terms in a projected ERPA Theory applied to the quasi-elastic (e,e') reaction
A systematic study of the influence of exchange terms in the longitudinal and
transverse nuclear response to quasi-elastic (e,e') reactions is presented. The
study is performed within the framework of the extended random phase
approximation (ERPA), which in conjuction with a projection method permits a
separation of various contributions tied to different physical processes. The
calculations are performed in nuclear matter up to second order in the residual
interaction for which we take a (pi+rho)-model with the addition of the
Landau-Migdal g'-parameter. Exchange terms are found to be important only for
the RPA-type contributions around the quasielastic peak.Comment: 29 pages, 6 figs (3 in postscript, 3 faxed on request), epsf.st
Ground State Correlations in 16O and 40Ca
We study the ground state properties of doubly closed shell nuclei O
and Ca in the framework of Correlated Basis Function theory using state
dependent correlations, with central and tensor components. The realistic
Argonne and two-nucleon potentials and three-nucleon
potentials of the Urbana class have been adopted. By means of the Fermi
Hypernetted Chain integral equations, in conjunction with the Single Operator
Chain approximation, we evaluate the ground state energy, one- and two-body
densities and electromagnetic and spin static responses for both nuclei. In
O we compare our results with the available Monte Carlo and Coupled
Cluster ones and find a satisfying agreement. As in the nuclear matter case
with similar interactions and wave functions, the nuclei result under-bound by
2--3 MeV/A.Comment: 33 RevTeX pages + 8 figures, to appear in Phys.Rev.
The Role of Final State Interactions in Quasielastic Fe Reactions at large
A relativistic finite nucleus calculation using a Dirac optical potential is
used to investigate the importance of final state interactions [FSI] at large
momentum transfers in inclusive quasielastic electronuclear reactions. The
optical potential is derived from first-order multiple scattering theory and
then is used to calculate the FSI in a nonspectral Green's function doorway
approach. At intermediate momentum transfers excellent predictions of the
quasielastic Fe experimental data for the longitudinal response
function are obtained. In comparisons with recent measurements at ~GeV/c the theoretical calculations of give good agreement for
the quasielastic peak shape and amplitude, but place the position of the peak
at an energy transfer of about ~MeV higher than the data.Comment: 13 pages typeset using revtex 3.0 with 6 postscript figures in
accompanying uuencoded file; submitted to Phys. Rev.
Interfering Doorway States and Giant Resonances. I: Resonance Spectrum and Multipole Strengths
A phenomenological schematic model of multipole giant resonances (GR) is
considered which treats the external interaction via common decay channels on
the same footing as the coherent part of the internal residual interaction. The
damping due to the coupling to the sea of complicated states is neglected. As a
result, the formation of GR is governed by the interplay and competition of two
kinds of collectivity, the internal and the external one. The mixing of the
doorway components of a GR due to the external interaction influences
significantly their multipole strengths, widths and positions in energy. In
particular, a narrow resonance state with an appreciable multipole strength is
formed when the doorway components strongly overlap.Comment: 20 pages, LaTeX, 3 ps-figures, to appear in PRC (July 1997
A Toy Model for Testing Finite Element Methods to Simulate Extreme-Mass-Ratio Binary Systems
Extreme mass ratio binary systems, binaries involving stellar mass objects
orbiting massive black holes, are considered to be a primary source of
gravitational radiation to be detected by the space-based interferometer LISA.
The numerical modelling of these binary systems is extremely challenging
because the scales involved expand over several orders of magnitude. One needs
to handle large wavelength scales comparable to the size of the massive black
hole and, at the same time, to resolve the scales in the vicinity of the small
companion where radiation reaction effects play a crucial role. Adaptive finite
element methods, in which quantitative control of errors is achieved
automatically by finite element mesh adaptivity based on posteriori error
estimation, are a natural choice that has great potential for achieving the
high level of adaptivity required in these simulations. To demonstrate this, we
present the results of simulations of a toy model, consisting of a point-like
source orbiting a black hole under the action of a scalar gravitational field.Comment: 29 pages, 37 figures. RevTeX 4.0. Minor changes to match the
published versio
Derivative-Coupling Models and the Nuclear-Matter Equation of State
The equation of state of saturated nuclear matter is derived using two
different derivative-coupling Lagrangians. We show that both descriptions are
equivalent and can be obtained from the sigma-omega model through an
appropriate rescaling of the coupling constants. We introduce generalized forms
of this rescaling to study the correlations amongst observables in infinite
nuclear matter, in particular, the compressibility and the effective nucleon
mass.Comment: 16 pages, 6 figures, 36 kbytes. To appear in Zeit. f. Phys. A
(Hadrons and Nuclei
The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors
Merlin has broad tumor-suppressor functions as its mutations have been identified in multiple benign tumors and malignant cancers. In all schwannomas, the majority of meningiomas and 1/3 of ependymomas Merlin loss is causative. In neurofibromatosis type 2, a dominantly inherited tumor disease because of the loss of Merlin, patients suffer from multiple nervous system tumors and die on average around age 40. Chemotherapy is not effective and tumor localization and multiplicity make surgery and radiosurgery challenging and morbidity is often considerable. Thus, a new therapeutic approach is needed for these tumors. Using a primary human in vitro model for Merlin-deficient tumors, we report that the Ras/Raf/mitogen-activated protein, extracellular signal-regulated kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) scaffold, kinase suppressor of Ras 1 (KSR1), has a vital role in promoting schwannomas development. We show that KSR1 overexpression is involved in many pathological phenotypes caused by Merlin loss, namely multipolar morphology, enhanced cell-matrix adhesion, focal adhesion and, most importantly, increased proliferation and survival. Our data demonstrate that KSR1 has a wider role than MEK1/2 in the development of schwannomas because adhesion is more dependent on KSR1 than MEK1/2. Immunoprecipitation analysis reveals that KSR1 is a novel binding partner of Merlin, which suppresses KSR1's function by inhibiting the binding between KSR1 and c-Raf. Our proteomic analysis also demonstrates that KSR1 interacts with several Merlin downstream effectors, including E3 ubiquitin ligase CRL4DCAF1. Further functional studies suggests that KSR1 and DCAF1 may co-operate to regulate schwannomas formation. Taken together, these findings suggest that KSR1 serves as a potential therapeutic target for Merlin-deficient tumors
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