A study of Women Entrepreneurship in Saudi Arabia

Today women entrepreneurs are increasing in Saudi Arabia. In order to understand about women entrepreneurs in Saudi Arabia, a sample of 200 women entrepreneurs were selected from various business areas. The research instrument adopted here was questionnaire with closed ended questions. The main aim of this study was to understand the reasons to start a business, identify the benefits realized and various advertising channels used by these women entrepreneurs. Based on the responses, it was understood that the reasons to start a business was to be an independent person, to get recognition in the society, to build a successful organization, to have innovativeness and to continue the family traditions. The identified business benefits were in the area of Information Technology adoption, Literacy rates, Availability of internet facilities, Government policies, Purchase behavior and Technology adoption. The preferred advertising channels for business were Facebook, Twitter, Business Websites as well others like google, Instagram and LinkedIn

Neisseria meningitidis nasopharyngeal carriage during the Hajj: A cohort study evaluating the need for ciprofloxacin prophylaxis

Background The annual Muslim pilgrimage has the potential of increase risk for acquisition of Neisseria meningitidis. Here, we evaluate the Hajj impact on the prevalence of N. meningitidis carriage in a paired and non-paired cohort of pilgrims. Secondary objectives were to calculate the compliance with recommended vaccination. Methods This is a prospective paired (arriving and departing), non-paired arriving and non-paired departing cohort study with the collection of nasopharyngeal samples at the start and the end of the Hajj. Results The study included unpaired arriving pilgrims at King Abdul Aziz International Airport (N = 1055), unpaired departing cohort (N = 373), and a paired cohort (N = 628) who were tested on arrival and departure. Meningococcal vaccination was received by all pilgrims, 98.2% received quadrivalent polysaccharide vaccine (ACWY), and 1.8% received meningococcal quadrivalent conjugate vaccine (MCV4). Only 1.61% and 23.03% received pneumococcal and influenza vaccines, respectively. Of the 1055 arriving unpaired pilgrim, 36 (3.4%) tested positive for nasopharyngeal carriage of N. meningitidis, and 24 (66.7%) of these were serogroup B, the remainder were non-groupable. Haemophilus influenza was detected among 45 (4.3%), and 11 (1%) carriers were positive for both N. meningitidis and H. influenzae. Out of 373 in the unpaired departing cohort, 6 (1.61%) tested positive for N. meningitidis, and 34 (9.1%) were positive for H. influenzae. Of the 628 paired cohort pilgrims, 36 (5.7%) pilgrims were positive for N. meningitidis at arrival and 16 (2.5%) pilgrims were positive after the hajj. Conclusion This the largest study of the epidemiology of N. meningitidis among pilgrims. The study showed a significant difference in the carriage between pilgrims from high endemicity and other pilgrims with a predominance of serogroup B. The continued use of ciprofloxacin as prophylactic antibiotics should be reconsidered as well as the consideration to add serogroup B as a required vaccination

Immunohistochemical evaluation of human epidermal growth factor receptor 2 and estrogen and progesterone receptors in breast carcinoma in Jordan

INTRODUCTION: Although breast carcinoma (BC) is the most common malignancy affecting Jordanian females and the affected population in Jordan is younger than that in the West, no information is available on its biological characteristics. Our aims in this study are to evaluate the expression of estrogen receptor (ER) and progesterone receptor (PR) and Her-2/neu overexpression in BC in Jordan, and to compare the expression of these with other prognostic parameters for BC such as histological type, histological grade, tumor size, patients' age, and number of lymph node metastases. METHOD: This is a retrospective study conducted in the Department of Pathology at Jordan University of Science and Technology. A confirmed 91 cases of BC diagnosed in the period 1995 to 1998 were reviewed and graded. We used immunohistochemistry to evaluate the expression of ER, PR, and Her-2. Immunohistochemical findings were correlated with age, tumor size, grade and axillary lymph node status. RESULTS: Her-2 was overexpressed in 24% of the cases. The mean age of Her-2 positive cases was 42 years as opposed to 53 years among Her-2 negative cases (p = 0.0001). Her-2 expression was inversely related to ER and PR expression. Her-2 positive tumors tended to be larger than Her-2 negative tumors with 35% overexpression among T3 tumors as opposed to 22% among T2 tumors (p = 0.13). Her-2 positive cases tended to have higher rates of axillary metastases, but this did not reach statistical significance. ER and PR positive cases were seen in older patients with smaller tumor sizes. CONCLUSION: Her-2 overexpression was seen in 24% of BC affecting Jordanian females. Her-2 overexpression was associated with young age at presentation, larger tumor size, and was inversely related to ER and PR expression. One-fifth of the carcinomas were Her-2 positive and ER negative. This group appears to represent an aggressive form of BC presenting at a young age with large primary tumors and a high rate of four or more axillary lymph node metastases

Numerical Evaluation of Steel Columns Buckling under Cyclic Loading

This paper aims to exhibit the use of finite element analysis as a numerical method to validate the experimental results of steel column stability under cyclic loading. Finite element package ANSYS was utilized for this purpose. The structural behavior of hollow box steel columns under the merged action of a constant axial load and cyclic lateral loads was investigated. Hot rolled unstiffened steel box column sections were simulated as cantilever-type columns as in common usage in the bridge piers. A nonlinear buckling finite element analysis was carried out in which both material and geometric nonlinearities were taken into account. The results show a reasonable agreement with Load and Resistance Factor Design (LRFD) formula. In addition, transient dynamic analysis was executed to determine the dynamic response of the specimens under the action of two loading tests: monotonic test and three cycle test. Isotropic strain-hardening and kinematic strain-hardening were included in simulating plastic deformation. It is shown that the non-linear finite element analysis shows good capabilities in simulating the buckling behavior of a steel column under cyclic loading

Parental Knowledge, Attitudes and Practices Towards Paediatric Ear Infections in Riyadh, Saudi Arabia: A quantitative study

ABSTRACT: Objectives: This study aimed to assess the knowledge, attitude and care-seeking practices of parents towards childhood ear infections in Riyadh, Saudi Arabia. Methods: This quantitative cross-sectional study was conducted in Riyadh, Saudi Arabia, between April and June 2018. An online survey was sent to a random selection of parents who were ≥18 years old with children of ≤10 years old. Associations between parental knowledge, attitude, care-seeking practices, socioeconomic status, level of education and age were assessed using the chi square test and logistic regression analysis. Results: A total of 782 subjects participated in this study (response rate: 78.2%). Most respondents were knowledgeable (76.2%), had a positive attitude (78.9%) and had positive care-seeking practices (89.5%). There was a statistically significant difference on both bivariate and multivariate analyses (P <0.05) between parental care seeking practice and knowledge. Parents who sought modern approaches to treatment were found to be almost nine times more likely to have a good attitude towards ear infections than those who did not seek treatment (odds ratio = 8.907, 95% confidence interval = 2.655–34.928; P <0.001). A statistically significant relationship was found between good care-seeking practice and age, as well as socioeconomic status (P <0.05 each). Conclusion: This study showed that knowledge, attitude and practice regarding paediatric ear infections were positive in the majority of parents in Riyadh, Saudi Arabia. Future studies should assess other factors that enhance the knowledge, attitude and practices regarding ear infections.Keywords: Otitis Media; Infection; Knowledge; Attitude; Pediatrics; Parents; Saudi Arabia

Power Efficient Scheduled-Based Medium Access Control Protocol over Wireless Sensor Networks

Abstract The flexible use of sensors has made them an attractive device to be deployed in almost every field of life such as health, military and home. Recent advancement in electronics and wireless communications has witnessed the development of low cost-sensor devices. While wireless sensor networks (WSNs) are flexible to use and less costly, they need to be more energy-efficient as they are operated by the battery. Mostly they are deployed in harsh environments where it is very difficult to change the batteries frequently. Several medium access control (MAC) algorithms have been developed for the energy-efficient acquisition of the wireless channel, however, none of them are satisfactory. In this paper, we proposed a medium access control algorithm called MAC-PE. MAC-PE is based on the concept of prioritized frames where prioritized frames are transmitted urgently. In addition, it uses scheduled-based MAC instead of accessing channel randomly. We found MAC-PE (Power-Efficient MAC) was efficient in terms of power consumption without sacrificing on the performance using NS-2

Therapeutic efficacy of Nigella sativa and Ziziphus lotus: sustainable strategies for diabetes, antimicrobial resistance, and health treatment

The pharmacological potential of Nigella sativa and Ziziphus lotus, two medicinal plants native to the United Arab Emirates (UAE), is explored in the context of sustainable healthcare strategies. Both plants have demonstrated notable antidiabetic and antimicrobial effects in preclinical studies. For instance, thymoquinone from Nigella sativa has shown glucose-lowering efficacy comparable to metformin in rodent models, while Ziziphus lotus extracts have outperformed acarbose in inhibiting carbohydrate-digesting enzymes. This paper synthesizes findings from ethnobotanical surveys, pharmacological research, and clinical literature to assess their therapeutic relevance. Additionally, it addresses challenges in standardization, sustainable harvesting, and environmental influence on phytochemical composition. While current evidence is promising, gaps remain in clinical validation and regulatory integration. This review aims to inform future research and policy, supporting the incorporation of UAE-native medicinal plants into evidence-based healthcare practices

Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients

Background Patients with acute medical illnesses are at prolonged risk for venous thrombosis. However, the appropriate duration of thromboprophylaxis remains unknown. Methods Patients who were hospitalized for acute medical illnesses were randomly assigned to receive subcutaneous enoxaparin (at a dose of 40 mg once daily) for 10±4 days plus oral betrixaban placebo for 35 to 42 days or subcutaneous enoxaparin placebo for 10±4 days plus oral betrixaban (at a dose of 80 mg once daily) for 35 to 42 days. We performed sequential analyses in three prespecified, progressively inclusive cohorts: patients with an elevated d-dimer level (cohort 1), patients with an elevated d-dimer level or an age of at least 75 years (cohort 2), and all the enrolled patients (overall population cohort). The statistical analysis plan specified that if the between-group difference in any analysis in this sequence was not significant, the other analyses would be considered exploratory. The primary efficacy outcome was a composite of asymptomatic proximal deep-vein thrombosis and symptomatic venous thromboembolism. The principal safety outcome was major bleeding. Results A total of 7513 patients underwent randomization. In cohort 1, the primary efficacy outcome occurred in 6.9% of patients receiving betrixaban and 8.5% receiving enoxaparin (relative risk in the betrixaban group, 0.81; 95% confidence interval [CI], 0.65 to 1.00; P=0.054). The rates were 5.6% and 7.1%, respectively (relative risk, 0.80; 95% CI, 0.66 to 0.98; P=0.03) in cohort 2 and 5.3% and 7.0% (relative risk, 0.76; 95% CI, 0.63 to 0.92; P=0.006) in the overall population. (The last two analyses were considered to be exploratory owing to the result in cohort 1.) In the overall population, major bleeding occurred in 0.7% of the betrixaban group and 0.6% of the enoxaparin group (relative risk, 1.19; 95% CI, 0.67 to 2.12; P=0.55). Conclusions Among acutely ill medical patients with an elevated d-dimer level, there was no significant difference between extended-duration betrixaban and a standard regimen of enoxaparin in the prespecified primary efficacy outcome. However, prespecified exploratory analyses provided evidence suggesting a benefit for betrixaban in the two larger cohorts. (Funded by Portola Pharmaceuticals; APEX ClinicalTrials.gov number, NCT01583218. opens in new tab.

Developing GIS-based water poverty and rainwater harvesting suitability maps for domestic use in the Dead Sea region (West Bank, Palestine)

In the arid region of the Dead Sea, water shortage and the inability to satisfy the increasing domestic water demand threatens sustainable development. In such situations, domestic rainwater harvesting is considered an efficient way to combat water poverty. This paper aims to develop domestic water poverty (DWP) and domestic rainwater harvesting suitability (DRWHS) maps for the West Bank, Palestine. The analytical hierarchy process (AHP) and the GIS-based weighted overlay summation process (WOSP) were utilized in the development of these maps. Results of the DWP map indicate that 57&thinsp;% of the West Bank is under high to very high poverty of domestic water. The DRWHS map shows that 60&thinsp;% of the West Bank is highly suitable for domestic rainwater harvesting. Spatial intersection (combined mapping) between DWP and DRWHS maps indicates that around 31&thinsp;% of the total West Bank areas could be classified as high potential locations (hotspot areas) for adopting rainwater harvesting techniques for domestic purposes. The developed maps are valuable to the stakeholders to better identify the best areas of rainwater harvesting in the West Bank.</p