Alfalfa but not milk in lamb's diet improves meat fatty acid profile and a-tocopherol content

To establish animal feeding recommendations, it is required to quantify whether the effects of combining dietary alfalfa and milk on meat composition of light lambs are overlapped or independent. This experiment aimed to evaluate the separate effects of dietary alfalfa and milk access on the light lamb carcass quality (10–11 kg), meat colour, chemical composition, fatty acid profile and a-tocopherol content. Thirty-two lambs were assigned to one of four treatments in a 2 × 2 factorial design. The factors were the inclusion of dietary forage (grazed alfalfa vs. concentrate-fed indoors) and lactation length (weaning at a target live-weight of 13 kg vs. suckling until slaughter at 22–24 kg). Dietary alfalfa but not milk supply improved conjugated linoleic acid isomers (CLA), omega-3 fatty acids and a-tocopherol contents in lamb meat without affecting meat colour attributes. Milk supply affected more the fatty acid profile (more saturated) than the a-tocopherol content of meat. Thus, dietary alfalfa improved CLA, omega-3 fatty acids and a-tocopherol content in light lamb without affecting the meat colour, whereas lengthening the lactation period did not provide benefits in terms of meat colour or healthy nutrient composition

Peritoneal tuberculosis due to Mycobacterium caprae

The incidence of tuberculosis in humans due to Mycobacterium caprae is very low and is almost confined to Europe. We report a case of a previously healthy 41-year-old Moroccan with a 6 month history of abdominal pain, weight loss, fatigue and diarrhea. A diagnosis of peritoneal tuberculosis due to M. caprae was mad

Gonyaulax taylorii, a new yessotoxins-producer dinoflagellate species from Chilean waters

In summer 2009, during a survey in Bahía Mejillones, a dense bloom of a dinoflagellate from the genus Gonyaulax was detected, as well as the presence of yessotoxin. Phytoplankton samples were analyzed in detail by light and scanning electron microscopy (SEM), revealing the presence of Gonyaulax taylorii. Morphological examination showed that the cells in the bloom fit in Gonyaulax jollifei Murray et Whitting sensu Dodge, subsequently classified as Gonyaulax taylorii by Carbonell-Moore. In this context, some inconsistencies have been found in regard to the holotype; the plate 1”’ appears as two plates, 1000 and 2000, showing a suture that does not exist in Dodge’s figure of G. jollifei, from where the holotype was drawn, nor within the samples collected. Therefore, this plate has been originally described erroneously as two plates named 1”’ and 2”’ instead of only one named 1000. After this correction, this species has five instead of six postcingular plates. For this reason, the description of this species must be emended. Phytoplankton net samples were found to containyessotoxin and homoyessotoxin, with concentrations below 1 pg cell!1. The present study identifies, therefore, the dinoflagellate G. taylorii as a new source of yessotoxins.Versión del editor3,083

HF spectrum activity prediction model based on HMM for cognitive radio applications

Although most of the research on Cognitive Radio is focused on communication bands above the HF upper limit (30 MHz), Cognitive Radio principles can also be applied to HF communications to make use of the extremely scarce spectrum more efficiently. In this work we consider legacy users as primary users since these users transmit without resorting to any smart procedure, and our stations using the HFDVL (HF Data+Voice Link) architecture as secondary users. Our goal is to enhance an efficient use of the HF band by detecting the presence of uncoordinated primary users and avoiding collisions with them while transmitting in different HF channels using our broad-band HF transceiver. A model of the primary user activity dynamics in the HF band is developed in this work to make short-term predictions of the sojourn time of a primary user in the band and avoid collisions. It is based on Hidden Markov Models (HMM) which are a powerful tool for modelling stochastic random processes and are trained with real measurements of the 14 MHz band. By using the proposed HMM based model, the prediction model achieves an average 10.3% prediction error rate with one minute-long channel knowledge but it can be reduced when this knowledge is extended: with the previous 8 min knowledge, an average 5.8% prediction error rate is achieved. These results suggest that the resulting activity model for the HF band could actually be used to predict primary users activity and included in a future HF cognitive radio based station

In the search of early stages biomarkers for non small cell lung cancer

Comunicaciones a congreso

Nanoscale imaging of buried topological defects with quantitative X-ray magnetic microscopy

This work is licensed under a Creative Commons Attribution 4.0 International License.-- et al.Advances in nanoscale magnetism increasingly require characterization tools providing detailed descriptions of magnetic configurations. Magnetic transmission X-ray microscopy produces element specific magnetic domain images with nanometric lateral resolution in films up to ∼100 nm thick. Here we present an imaging method using the angular dependence of magnetic contrast in a series of high resolution transmission X-ray microscopy images to obtain quantitative descriptions of the magnetization (canting angles relative to surface normal and sense). This method is applied to 55-120 nm thick ferromagnetic NdCo 5 layers (canting angles between 65° and 22°), and to a NdCo 5 film covered with permalloy. Interestingly, permalloy induces a 43° rotation of Co magnetization towards surface normal. Our method allows identifying complex topological defects (merons or 1/2 skyrmions) in a NdCo 5 film that are only partially replicated by the permalloy overlayer. These results open possibilities for the characterization of deeply buried magnetic topological defects, nanostructures and devices.Work supported by Spanish MINECO under grant FIS2013-45469. A. Hierro-Rodriguez acknowledges support from FCT of Portugal (Grant SFRH/BPD/90471/2012). C. Blanco-Roldán thanks support from CSIC JAE Predoc Program.Peer Reviewe

Application of several pretreatment technologies to a wastewater effluent of a petrochemical industry finally treated with reverse osmosis

[EN] This work studies the adequacy of different reverse osmosis (RO) pretreatments applied to different petrochemical wastewater effluents. Three effluents from a caprolactam factory were analysed: ion-exchange resin washing effluent (RWE), batch reactor washing effluent and factory outlet effluent. Coagulation–flocculation, microfiltration (MF) and ultrafiltration (UF) were tested as RO pretreatments. Various inorganic coagulants (Aluminium Chloride, Iron (III) Chloride, Aluminium Sulphate and polyaluminium chloride), commercial coagulants (Nophos and ACO) and commercial flocculants (polyacrylamide, CH-30 and active polyfloc) were tested at different dosages and stirring speeds. The highest removal of suspended solids (SS) and the lowest turbidity were obtained for the ion-exchange RWE. Two combinations of coagulants and flocculants were chosen as the most suitable conditions for the coagulation–flocculation process. The ion-exchange RWE was further treated with a combination of MF followed by UF. SS were completely removed and turbidity decreased to 0.136 NTU. The silt density index at 15 min was reduced to 6.41.The authors of this work wish to gratefully acknowledge the financial support from the Generalitat Valenciana through the programme “Ayudas para la realizacio´n de proyectos I+D para grupos de investigacio´n emergentes GV/2013”.Vincent Vela, MC.; Alvarez Blanco, S.; Lora García, J.; Carbonell Alcaina, C.; Sáez Muñoz, M. (2014). Application of several pretreatment technologies to a wastewater effluent of a petrochemical industry finally treated with reverse osmosis. Desalination and Water Treatment. 1-9. doi:10.1080/19443994.2014.939866S19Benito-Alcázar, C., Vincent-Vela, M. C., Gozálvez-Zafrilla, J. M., & Lora-García, J. (2010). Study of different pretreatments for reverse osmosis reclamation of a petrochemical secondary effluent. Journal of Hazardous Materials, 178(1-3), 883-889. doi:10.1016/j.jhazmat.2010.02.020Madaeni, S. S., & Eslamifard, M. R. (2010). Recycle unit wastewater treatment in petrochemical complex using reverse osmosis process. Journal of Hazardous Materials, 174(1-3), 404-409. doi:10.1016/j.jhazmat.2009.09.067Kim, H.-C., & Dempsey, B. A. (2008). Effects of wastewater effluent organic materials on fouling in ultrafiltration. Water Research, 42(13), 3379-3384. doi:10.1016/j.watres.2008.04.021Karabacakoğlu, B., Tezakıl, F., & Güvenç, A. (2014). Removal of hardness by electrodialysis using homogeneous and heterogeneous ion exchange membranes. Desalination and Water Treatment, 54(1), 8-14. doi:10.1080/19443994.2014.880159Gare, S. (2002). RO systems: the importance of pre-treatment. Filtration & Separation, 39(1), 22-27. doi:10.1016/s0015-1882(02)80047-7Garg, A., Mishra, I. M., & Chand, S. (2010). Effectiveness of coagulation and acid precipitation processes for the pre-treatment of diluted black liquor. Journal of Hazardous Materials, 180(1-3), 158-164. doi:10.1016/j.jhazmat.2010.04.008Verma, S., Prasad, B., & Mishra, I. M. (2010). Pretreatment of petrochemical wastewater by coagulation and flocculation and the sludge characteristics. Journal of Hazardous Materials, 178(1-3), 1055-1064. doi:10.1016/j.jhazmat.2010.02.047Garrote, J. (1995). Treatment of tannery effluents by a two step coagulation/flocculation process. Water Research, 29(11), 2605-2608. doi:10.1016/0043-1354(94)00312-uSanto, C. E., Vilar, V. J. P., Botelho, C. M. S., Bhatnagar, A., Kumar, E., & Boaventura, R. A. R. (2012). Optimization of coagulation–flocculation and flotation parameters for the treatment of a petroleum refinery effluent from a Portuguese plant. Chemical Engineering Journal, 183, 117-123. doi:10.1016/j.cej.2011.12.041Wang, J.-P., Chen, Y.-Z., Wang, Y., Yuan, S.-J., & Yu, H.-Q. (2011). Optimization of the coagulation-flocculation process for pulp mill wastewater treatment using a combination of uniform design and response surface methodology. Water Research, 45(17), 5633-5640. doi:10.1016/j.watres.2011.08.023Rossini, M., Garrido, J. G., & Galluzzo, M. (1999). Optimization of the coagulation–flocculation treatment: influence of rapid mix parameters. Water Research, 33(8), 1817-1826. doi:10.1016/s0043-1354(98)00367-4Guida, M., Mattei, M., Della Rocca, C., Melluso, G., & Meriç, S. (2007). Optimization of alum-coagulation/flocculation for COD and TSS removal from five municipal wastewater. Desalination, 211(1-3), 113-127. doi:10.1016/j.desal.2006.02.086HABERKAMP, J., RUHL, A., ERNST, M., & JEKEL, M. (2007). Impact of coagulation and adsorption on DOC fractions of secondary effluent and resulting fouling behaviour in ultrafiltration. Water Research, 41(17), 3794-3802. doi:10.1016/j.watres.2007.05.029Petrov, S., & Stoichev, P. (2002). Reagent ultrafiltration purification of water contaminated with reactive dyes. Filtration & Separation, 39(8), 35-34. doi:10.1016/s0015-1882(02)80229-4Shon, H. K., Vigneswaran, S., Ngo, H. H., & Ben Aim, R. (2005). Is semi-flocculation effective as pretreatment to ultrafiltration in wastewater treatment? Water Research, 39(1), 147-153. doi:10.1016/j.watres.2004.09.003Hatt, J. W., Germain, E., & Judd, S. J. (2011). Precoagulation-microfiltration for wastewater reuse. Water Research, 45(19), 6471-6478. doi:10.1016/j.watres.2011.09.039Dryden Aqua Ltd, Edinburgh, 2013. Available from: www.DrydenAqua.com (April 6, 2013).Sincero, A. P., & Sincero, G. A. (2002). Physical-Chemical Treatment of Water and Wastewater. doi:10.1201/978142003190

A new scenario in metastatic renal cell carcinoma: a SOG‑GU consensus

[Abstract] Background This article describes and compares approved targeted therapies and the newer immunotherapy agents. Materials and methods This article especially performs an in-depth review of currently available data for tivozanib, explaining its mechanism of action, its safety profle and its role as an efcacy drug in the management of renal cancer. Results Despite the fact that the treatment of advanced RCC has been dramatically modifed in recent years, durable remissions are scarce and it remains a lethal disease. For frst- and second-line therapy, there is now growing evidence to guide the selection of the appropriate treatment. Conclusions Several TKIs are standard of care at diferent settings. Among those approved TKIs, tivozanib has similar efcacy than others with a better safety profle. The use of prognostic factors is critical to the selection of optimal therapy

The second flight of the SUNRISE balloon-borne solar observatory: overview of instrument updates, the flight, the data and first results

The SUNRISE balloon-borne solar observatory, consisting of a 1~m aperture telescope that provided a stabilized image to a UV filter imager and an imaging vector polarimeter, carried out its second science flight in June 2013. It provided observations of parts of active regions at high spatial resolution, including the first high-resolution images in the Mg~{\sc ii}~k line. The obtained data are of very high quality, with the best UV images reaching the diffraction limit of the telescope at 3000~\AA\ after Multi-Frame Blind Deconvolution reconstruction accounting for phase-diversity information. Here a brief update is given of the instruments and the data reduction techniques, which includes an inversion of the polarimetric data. Mainly those aspects that evolved compared with the first flight are described. A tabular overview of the observations is given. In addition, an example time series of a part of the emerging active region NOAA AR~11768 observed relatively close to disk centre is described and discussed in some detail. The observations cover the pores in the trailing polarity of the active region, as well as the polarity inversion line where flux emergence was ongoing and a small flare-like brightening occurred in the course of the time series. The pores are found to contain magnetic field strengths ranging up to 2500~G and, while large pores are clearly darker and cooler than the quiet Sun in all layers of the photosphere, the temperature and brightness of small pores approach or even exceed those of the quiet Sun in the upper photosphere.Comment: Accepted for publication in The Astrophysical Journa