3,623 research outputs found
Capital Flows to developing countries: does the emperor have clothes?
This paper begins by examining the pattern of capital flows first to low-income countries, and then to emerging economies. In both cases, we see a dramatic collapse in the last several years. The evolving determinants of these trends in FDI flows (the principal category of private flows to low-income countries) and other capital flows are analysed. The behaviour of flows to emerging economies heavily influences both present and potential future flows to low-income countries. The paper concludes with the policy implications at both source countries and low-income recipient countries.
Sequence biases in large scale gene expression profiling data
We present the results of a simple, statistical assay that measures the G+C content sensitivity bias of gene expression experiments without the requirement of a duplicate experiment. We analyse five gene expression profiling methods: Affymetrix GeneChip, Long Serial Analysis of Gene Expression (LongSAGE), LongSAGELite, âClassicâ Massively Parallel Signature Sequencing (MPSS) and âSignatureâ MPSS. We demonstrate the methods have systematic and random errors leading to a different G+C content sensitivity. The relationship between this experimental error and the G+C content of the probe set or tag that identifies each gene influences whether the gene is detected and, if detected, the level of gene expression measured. LongSAGE has the least bias, while Signature MPSS shows a strong bias to G+C rich tags and Affymetrix data show different bias depending on the data processing method (MAS 5.0, RMA or GC-RMA). The bias in the Affymetrix data primarily impacts genes expressed at lower levels. Despite the larger sampling of the MPSS library, SAGE identifies significantly more genes (60% more RefSeq genes in a single comparison)
Extending Construal Level Theory to Distributed Teams: Perception and Evaluation of Distant Others
Building on prior research on distributed teams that has identified physical and temporal distance as impediments to collaboration and relationship development, this paper explores how and why we treat geographically distant others differently from those who are proximal. According to construal level theory, physically- or temporally-distant events or objects are more psychologically distant and are more likely to be described in terms of their more general characteristics, while views of more proximal events or objects will be more detailed and nuanced. We extend construal level theory to the distributed team context by advancing propositions about how group members perceive and evaluate distant others in contrast to proximal others. By comparing to alternative computer-mediated communication and social psychological theories that have been applied to this phenomenon, we show that construal level theory offers parsimonious explanations as well as novel predictions about how and why we perceive and evaluate distant others differently. The paper then considers theoretical, methodological, and practical implications of construal level theory for distributed teams and other virtual settings
Challenging sex segregation: A philosophical evaluation of the football associationâs rules on mixed football
The Football Association (FA) has been under pressure to allow girls to play in mixed teams since 1978, following 12-year old Theresa Bennettâs application to play with boys in a local league. In 1991, over a decade after Bennettâs legal challenge, the FA agreed to remove its ban on mixed football and introduced Rule C4 in order to permit males and females to play together in competitive matches under the age of 11. More recently, following a campaign by parents, coaches, local Members of Parliament and the Womenâs Sport Foundation, the FA agreed to trial mixed football for the under-12 to under-15 age categories in order to establish, among other things, the risk of injury to players in sex-integrated competitions. A series of exponential changes ensued: between 2010 and 2014, the age at which mixed football was permitted increased from U11 to U16. In 2015, the FA announced the decision to raise the age limit on mixed football from U16 to U18 for the forthcoming 2015â2016 season. We critically examine the reasons given by the FA for enforcing segregated participation beyond the age of 18, namely that males have an unfair advantage and that females face an unacceptable risk of injury. We also discuss the argument that removing the ban might harm the womenâs game. In conclusion, we suggest that the FA ought to abandon the ban on mixed football over the age of 18
Arene oxidation with malonoyl peroxides
Malonoyl peroxide 7, prepared in a single step from the commercially available diacid, is an effective reagent for the
oxidation of aromatics. Reaction of an arene with peroxide 7 at room temperature leads to the corresponding protected phenol
which can be unmasked by aminolysis. An ionic mechanism consistent with the experimental findings and supported by isotopic
labeling, Hammett analysis, EPR investigations and reactivity profile studies is proposed
Rejuvenated radio galaxies J0041+3224 and J1835+6204 : how long can the quiescent phase of nuclear activity last?
We present radio observations of two well-known doubledouble radio galaxies, J0041+3224 and J1835+6204, at frequencies ranging from 150 to 8460 MHz, using both the Giant Metrewave Radio Telescope and the Very Large Array. These observations, over a large radio frequency range, enable us to determine the spectra of the inner and outer lobes. Our detailed spectral ageing analysis of their inner and outer lobes demonstrates that the outer doubles of doubledouble radio galaxies are created by the previous cycle of activity, while the inner doubles are due to the present cycle of activity. The (core subtracted) spectra of the inner doubles of both sources are power laws over a large frequency range. We found that the duration of the quiescent phase of J0041+3224 is between 4 and 28 per cent of the active phase of the previous activity. The outer north-western lobe of J1835+6204 has a compact hotspot and the regions of both the outer hotspots have close to power-law (rather than curved) spectra, which indicates that the outer lobes are still fed by jet material ejected in the previous episode just before the central engine stopped powering the jet. We estimate that the duration of the quiescent phase of J1835+6204 is ?5 per cent of the duration of the active phase of the previous activity. Therefore, we conclude that the duration of the quiescent phase can be as short as a few per cent of the active phase in radio galaxies of this type.Peer reviewe
The Predictive Validity of the MoCA-LD for Assessing Mental Capacity in Adults with Intellectual Disabilities
Mental capacity assessments currently rely on subjective opinion. Researchers have yet to explore the association between key cognitive functions of rational decision-making and mental capacity classifications for people with intellectual disabilities. Sixty-three adults completed the Montreal Cognitive Assessment, which yielded estimates of their overall cognitive ability (MoCA-LD) as well as their memory, attention, language and executive functioning. Differences in scores were explored for those who had, and lacked, capacity and logistic regression was used to test the predictive validity of each measure. There were significant differences between both groups for all measures. Logistic regression identified MoCA-LD as a significant predictor of capacity assessment outcomes. ROC curve analysis provided novel, evidence-based benchmarks to help guide clinical practice based on individual MoCA-LD scores. This study offers a foundation for more objective approaches to mental capacity assessment. This demonstrates that assessments of cognitive ability can yield information that is helpful for mental capacity evaluations
Bayesian paternity analysis and mating patterns in a parasitic nematode, Trichostrongylus tenuis
Mating behaviour is a fundamental aspect of the evolutionary ecology of sexually reproducing species, but one that has been under-researched in parasitic nematodes. We analysed mating behaviour in the parasitic nematode Trichostrongylus tenuis by performing a paternity analysis in a population from a single red grouse host. Paternity of the 150 larval offspring of 25 mothers (sampled from one of the two host caeca) was assigned among 294 candidate fathers (sampled from both caeca). Each candidate father's probability of paternity of each offspring was estimated from 10-locus microsatellite genotypes. Seventy-six (51%) offspring were assigned a father with a probability of >0.8, and the estimated number of unsampled males was 136 (95% credible interval (CI) 77-219). The probability of a male from one caecum fathering an offspring in the other caecum was estimated as 0.024 (95% CI 0.003-0.077), indicating that the junction of the caeca is a strong barrier to dispersal. Levels of promiscuity (defined as the probability of two of an adult's offspring sharing only one parent) were high for both sexes. Variance in male reproductive success was moderately high, possibly because of a combination of random mating and high variance in post-copulatory reproductive success. These results provide the first data on individual mating behaviour among parasitic nematodes
Sports coaching and the law of negligence: implications for coaching practice
The ordinary principles of the law of negligence are applicable in the context of sport, including claims brought against volunteer and professional coaches. Adopting the perspective of the coach, this article intends to raise awareness of the emerging intersection between the law of negligence and sports coaching, by utilising an interdisciplinary analysis designed to better safeguard and reassure coaches mindful of legal liability. Detailed scrutiny of two cases concerning alleged negligent coaching, with complementary discussion of some of the ethical dilemmas facing modern coaches, reinforces the legal duty and obligation of all coaches to adopt objectively reasonable and justifiable coaching practices when interacting with athletes. Problematically, since research suggests that some coaching practice may be underpinned by âentrenched legitimacyâ and âuncritical inertiaâ, it is argued that coach education and training should place a greater emphasis on developing a coachâs awareness and understanding of the evolving legal context in which they discharge the duty of care incumbent upon them
Long-term trends of inorganic chlorine from ground-based infrared solar spectra: Past increases and evidence for stabilization
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