569 research outputs found

    Saturated simplicial complexes

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    AbstractAmong shellable complexes a certain class has maximal modular homology, and these are the so-called saturated complexes. We extend the notion of saturation to arbitrary pure complexes and give a survey of their properties. It is shown that saturated complexes can be characterized via the p-rank of incidence matrices and via the structure of links. We show that rank-selected subcomplexes of saturated complexes are also saturated, and that order complexes of geometric lattices are saturated

    High salt recruits aversive taste pathways

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    In the tongue, distinct classes of taste receptor cells detect the five basic tastes; sweet, sour, bitter, sodium salt and umami. Among these qualities, bitter and sour stimuli are innately aversive, whereas sweet and umami are appetitive and generally attractive to animals. By contrast, salty taste is unique in that increasing salt concentration fundamentally transforms an innately appetitive stimulus into a powerfully aversive one. This appetitive–aversive balance helps to maintain appropriate salt consumption, and represents an important part of fluid and electrolyte homeostasis. We have shown previously that the appetitive responses to NaCl are mediated by taste receptor cells expressing the epithelial sodium channel, ENaC, but the cellular substrate for salt aversion was unknown. Here we examine the cellular and molecular basis for the rejection of high concentrations of salts. We show that high salt recruits the two primary aversive taste pathways by activating the sour- and bitter-taste-sensing cells. We also demonstrate that genetic silencing of these pathways abolishes behavioural aversion to concentrated salt, without impairing salt attraction. Notably, mice devoid of salt-aversion pathways show unimpeded, continuous attraction even to very high concentrations of NaCl. We propose that the ‘co-opting’ of sour and bitter neural pathways evolved as a means to ensure that high levels of salt reliably trigger robust behavioural rejection, thus preventing its potentially detrimental effects on health

    Embeddings of U 3 (8), Sz (8) and the Rudvalis group in algebraic groups of type E 7

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46579/1/222_2005_Article_BF01231561.pd

    The Taste of Carbonation

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    Carbonated beverages are commonly available and immensely popular, but little is known about the cellular and molecular mechanisms underlying the perception of carbonation in the mouth. In mammals, carbonation elicits both somatosensory and chemosensory responses, including activation of taste neurons. We have identified the cellular and molecular substrates for the taste of carbonation. By targeted genetic ablation and the silencing of synapses in defined populations of taste receptor cells, we demonstrated that the sour-sensing cells act as the taste sensors for carbonation, and showed that carbonic anhydrase 4, a glycosylphosphatidylinositol-anchored enzyme, functions as the principal CO_2 taste sensor. Together, these studies reveal the basis of the taste of carbonation as well as the contribution of taste cells in the orosensory response to CO_2

    ‘School, family and then hockey!’ Coaches’ views on dual career in ice hockey

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    Despite the extensive research into coaches’ roles in supporting athletic development and motivation for sport, few studies have examined coaches’ attitudes and practices towards athletes’ dual careers. The present study extends European research into athletes’ dual careers by examining Finnish ice hockey coaches’ attitudes and practices surrounding players’ education. Ten male coaches aged 27–52 participated in semi-structured interviews. The data were analysed with an existential-narrative theoretical framework and with thematic and structural narrative analysis. Three composite vignettes were created entitled ‘supporting athletic development and players in reaching their own goals’, ‘enjoyment and physically active lifestyle’ and ‘developing good persons’. The analysis revealed that although all coaches embraced the official rhetoric where school is a priority over ice hockey, most of them had few practical examples of how this view had informed their coaching practice. It is concluded that young players may be easily lured into dreams of professionalism, whereas coaches’ dominant narrative of education as a back-up may be ineffective to spark athletes’ interest and engagement with education. © 2017, © The Author(s) 2017

    POSSIBILITIES OF OPEN ERUPTION ELIMINATION BY DRILLING TOOLS

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    The most important raw materials for different industries are oil and natural gas. With increasing consumption, the demand for drilling and the quality of production increases. Therefore, the exploration and production of hydrocarbons requires not only first-class machinery and technological equipment, but also qualified personnel. Exploration and drilling, production of hydrocarbons, like any other industry, cannot avoid accidents, emergencies and catastrophes. The worst type of well accident is undoubtedly an open eruption of the extracted crude oil. Open eruption can lead to serious injuries to the rig personnel, damage and destruction of equipment, negative environmental impact and loss of crude oil. Exploratory drilling can cause the rise of pressure and its subsequent manifestations. During the first deep drilling, there may not be enough information about the drilled horizons. If the reservoir pressure in the production horizon is higher than the hydrostatic pressure of the fluid in the well (for example, drilling mud), the formation fluids flow into the well and move towards the surface, which causes open eruption. The rig personnel must be properly trained to be able to recognize the occurrence of rising pressure by various signs and to respond effectively to the situation. Sometimes, under the influence of the human factor or equipment failure, open eruption still occurs. The article discusses the possibilities of eliminating open eruptions with drilling tools

    Cashing Out the Great Cannon? On Browser-Based DDoS Attacks and Economics

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    The Great Cannon DDoS attack has shown that HTML/JavaScript can be used to launch HTTP-based DoS attacks. In this paper, we identify options that could allow the implementation of the general idea of browser-based DDoS botnets and review ways how attackers can acquire bots (e.g., typosquatting and malicious ads). We then assess the DoS impact of browser features and show that at least three JavaScript-based techniques can orchestrate clients to send thousands of HTTP requests per second. Seeing the vats potential, we evaluate the economics of browser-based botnets and show that their cost are about as high as traditional DDoS botnets—while giving far less flexibility in terms of attack features and control over the bots. Finally, we discuss victim- and browser-side countermeasures

    Gravitational wave astronomy of single sources with a pulsar timing array

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    Abbreviated: We investigate the potential of detecting the gravitational wave from individual binary black hole systems using pulsar timing arrays (PTAs) and calculate the accuracy for determining the GW properties. This is done in a consistent analysis, which at the same time accounts for the measurement of the pulsar distances via the timing parallax. We find that, at low redshift, a PTA is able to detect the nano-Hertz GW from super massive black hole binary systems with masses of \sim10^8 - 10^{10}\,M_{\sun} less than ∼105\sim10^5\,years before the final merger, and those with less than ∼103−104\sim10^3 - 10^4 years before merger may allow us to detect the evolution of binaries. We derive an analytical expression to describe the accuracy of a pulsar distance measurement via timing parallax. We consider five years of bi-weekly observations at a precision of 15\,ns for close-by (∼0.5−1\sim 0.5 - 1\,kpc) pulsars. Timing twenty pulsars would allow us to detect a GW source with an amplitude larger than 5×10−175\times 10^{-17}. We calculate the corresponding GW and binary orbital parameters and their measurement precision. The accuracy of measuring the binary orbital inclination angle, the sky position, and the GW frequency are calculated as functions of the GW amplitude. We note that the "pulsar term", which is commonly regarded as noise, is essential for obtaining an accurate measurement for the GW source location. We also show that utilizing the information encoded in the GW signal passing the Earth also increases the accuracy of pulsar distance measurements. If the gravitational wave is strong enough, one can achieve sub-parsec distance measurements for nearby pulsars with distance less than ∼0.5−1\sim 0.5 - 1\,kpc.Comment: 16 pages, 5 figure,, accepted by MNRA
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