24,873 research outputs found
Method of measuring thermal conductivity of high performance insulation
Method accurately measures the thermal conductivity of high-performance sheet insulation as a discrete function of temperature. It permits measurements to be made at temperature drops of approximately 10 degrees F across the insulation and ensures measurement accuracy by minimizing longitudinal heat losses in the system
Semi-Classical Description of Antiproton Capture on Atomic Helium
A semi-classical, many-body atomic model incorporating a momentum-dependent
Heisenberg core to stabilize atomic electrons is used to study antiproton
capture on Helium. Details of the antiproton collisions leading to eventual
capture are presented, including the energy and angular momentum states of
incident antiprotons which result in capture via single or double electron
ionization, i.e. into [He or He], and the
distribution of energy and angular momentum states following the Auger cascade.
These final states are discussed in light of recently reported, anomalously
long-lived antiproton states observed in liquid He.Comment: 15 pages, 9 figures may be obtained from authors, Revte
Modeling of the processing and removal of trace gas and aerosol species by Arctic radiation fogs and comparison with measurements
A Lagrangian radiation fog model is applied to a fog event at Summit, Greenland. The model simulates the formation and dissipation of fog. Included in the model are detailed gas and aqueous phase chemistry, and deposition of chemical species with fog droplets. Model predictions of the gas phase concentrations of H2O2, HCOOH, SO2, and HNO3 as well as the fog fluxes of S(VI), N(V), H2O2, and water are compared with measurements. The predicted fluxes of S(VI), N(V), H2O2, and fog water generally agree with measured values. Model results show that heterogeneous SO2 oxidation contributes to approximately 40% of the flux of S(VI) for the modeled fog event, with the other 60% coming from preexisting sulfate aerosol. The deposition of N(V) with fog includes contributions from HNO3 and NO2 initially present in the air mass. HNO3 directly partitions into the aqueous phase to create N(V), and NO2 forms N(V) through reaction with OH and the nighttime chemistry set of reactions which involves N2O5 and water vapor. PAN contributes to N(V) by gas phase decomposition to NO2, and also by direct aqueous phase decomposition. The quantitative contributions from each path are uncertain since direct measurements of PAN and NO2 are not available for the fog event. The relative contributions are discussed based on realistic ranges of atmospheric concentrations. Model results suggest that in addition to the aqueous phase partitioning of the initial HNO3 present in the air mass, the gas phase decomposition of PAN and subsequent reactions of NO2 with OH as well as nighttime nitrate chemistry may play significant roles in depositing N(V) with fog. If a quasi-liquid layer exists on snow crystals, it is possible that the reactions taking place in fog droplets also occur to some extent in clouds as well as at the snow surface
System and method for monitoring cellular activity
A system and method for monitoring cellular activity in a cellular specimen. According to one embodiment, a plurality of excitable markers are applied to the specimen. A multi-photon laser microscope is provided to excite a region of the specimen and cause fluorescence to be radiated from the region. The radiating fluorescence is processed by a spectral analyzer to separate the fluorescence into respective wavelength bands. The respective bands of fluorescence are then collected by an array of detectors, with each detector receiving a corresponding one of the wavelength bands
Metformin as a Therapeutic Target in Endometrial Cancers.
Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of hyperestrogenic and hyperinsulinemic states. This has consequently lead to an increase in other hormone-responsive cancers as well e.g., breast and ovarian cancer. The correlation between obesity, hyperglycemia, and endometrial cancer has highlighted the important role of metabolism in cancer establishment and persistence. Tumor-mediated reprogramming of the microenvironment and macroenvironment can range from induction of cytokines and growth factors to stimulation of surrounding stromal cells to produce energy-rich catabolites, fueling the growth, and survival of cancer cells. Such mechanisms raise the prospect of the metabolic microenvironment itself as a viable target for treatment of malignancies. Metformin is a biguanide drug that is a first-line treatment for type 2 diabetes that has beneficial effects on various markers of the metabolic syndrome. Many studies suggest that metformin shows potential as an adjuvant treatment for uterine and other cancers. Here, we review the evidence for metformin as a treatment for cancers of the endometrium. We discuss the available clinical data and the molecular mechanisms by which it may exert its effects, with a focus on how it may alter the tumor microenvironment. The pleiotropic effects of metformin on cellular energy production and usage as well as intercellular and hormone-based interactions make it a promising candidate for reprogramming of the cancer ecosystem. This, along with other treatments aimed at targeting tumor metabolic pathways, may lead to novel treatment strategies for endometrial cancer
Fiber transport of spatially entangled photons
Entanglement in the spatial degrees of freedom of photons is an interesting
resource for quantum information. For practical distribution of such entangled
photons it is desireable to use an optical fiber, which in this case has to
support multiple transverse modes. Here we report the use of a hollow-core
photonic crystal fiber to transport spatially entangled qubits.Comment: 4 pages, 4 figure
European Non-native Species in Aquaculture Risk Analysis Scheme - a summary of assessment protocols and decision support tools for use of alien species in aquaculture
The European Non-native Species in Aquaculture Risk Analysis Scheme (ENSARS) was developed in response to European 'Council Regulation No. 708/2007 of 11 June 2007 concerning use of alien and locally absent species in aquaculture' to provide protocols for identifying and evaluating the potential risks of using non-native species in aquaculture. ENSARS is modular in structure and adapted from non-native species risk assessment schemes developed by the European and Mediterranean Plant Protection Organisation and for the UK. Seven of the eight ENSARS modules contain protocols for evaluating the risks of escape, introduction to and establishment in open waters, of any non-native aquatic organism being used (or associated with those used) in aquaculture, that is, transport pathways, rearing facilities, infectious agents, and the potential organism, ecosystem and socio-economic impacts. A concluding module is designed to summarise the risks and consider management options. During the assessments, each question requires the assessor to provide a response and confidence ranking for that response based on expert opinion. Each module can also be used individually, and each requires a specific form of expertise. Therefore, a multidisciplinary assessment team is recommended for its completion
Higgs bosons near 125 GeV in the NMSSM with constraints at the GUT scale
We study the NMSSM with universal Susy breaking terms (besides the Higgs
sector) at the GUT scale. Within this constrained parameter space, it is not
difficult to find a Higgs boson with a mass of about 125 GeV and an enhanced
cross section in the diphoton channel. An additional lighter Higgs boson with
reduced couplings and a mass <123 GeV is potentially observable at the LHC. The
NMSSM-specific Yukawa couplings lambda and kappa are relatively large and
tan(beta) is small, such that lambda, kappa and the top Yukawa coupling are of
order 1 at the GUT scale. The lightest stop can be as light as 105 GeV, and the
fine-tuning is modest. WMAP constraints can be satisfied by a dominantly
higgsino-like LSP with substantial bino, wino and singlino admixtures and a
mass of ~60-90 GeV, which would potentially be detectable by XENON100.Comment: 20 pages, 14 figure
The interaction between transpolar arcs and cusp spots
Transpolar arcs and cusp spots are both auroral phenomena which occur when
the interplanetary magnetic field is northward. Transpolar arcs are associated
with magnetic reconnection in the magnetotail, which closes magnetic flux and
results in a "wedge" of closed flux which remains trapped, embedded in the
magnetotail lobe. The cusp spot is an indicator of lobe reconnection at the
high-latitude magnetopause; in its simplest case, lobe reconnection
redistributes open flux without resulting in any net change in the open flux
content of the magnetosphere. We present observations of the two phenomena
interacting--i.e., a transpolar arc intersecting a cusp spot during part of its
lifetime. The significance of this observation is that lobe reconnection can
have the effect of opening closed magnetotail flux. We argue that such events
should not be rare
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