Performance assessment of low-cost thermal cameras for medical applications

Thermal imaging is a promising technology in the medical field. Recent developments in low-cost infrared (IR) sensors, compatible with smartphones, provide competitive advantages for home-monitoring applications. However, these sensors present reduced capabilities compared to more expensive high-end devices. In this work, the characterization of thermal cameras is described and carried out. This characterization includes non-uniformity (NU) effects and correction as well as the thermal cameras´ dependence on room temperature, noise-equivalent temperature difference (NETD), and response curve stability with temperature. Results show that low-cost thermal cameras offer good performance, especially when used in temperature-controlled environments, providing evidence of the suitability of such sensors for medical applications, particularly in the assessment of diabetic foot ulcers on which we focused this study.This research was funded by the IACTEC Technological Training program, grant number TF INNOVA 2016-2021, and by the European Union Interreg-Mac funding program, grant number MAC/1.1.b/098 (MACbioIDi project)

Anthropometric characteristics, quality of life and functional capacity in adults living with HIV in Puerto Rico

Survival and longevity rates in people living with HIV (HIV+) have increased with the availability and use of antiretroviral therapy (ART). However, despite the above HIV+ adults treated with ART have a higher risk of developing dyslipidemia and high waist circumference. In addition, they have lower cardiorespiratory fitness, loss of muscle mass, reduced balance, and reduced functional capacity, which affects their quality of life. To explore the impact of balance perception, treadmill time, grip strength, body mass index (BMI), and waist-to-height ratio (WHtR) on quality of life in Latino Hispanic people living with HIV. This study recruited twenty-five participants from a community-based center, La Perla de Gran Precio, in San Juan, Puerto Rico, with the medical diagnosis of HIV. Descriptive measures were obtained for all variables of interest, and correlation and regression analyses were used to assess the associations between functional capacity, quality of life, and anthropometric measures. Result: Men had greater left- and right-hand grip strength than women (86.9±18.8, 56.9±26.8 kg; p=0.003 and 87.6±15.1 vs. 61.4±26.6 kg; p =0.004). Two anthropometric variables showed a trend toward a moderate positive correlation with quality of life:  WHtR (r= -0.38, p =0.12) and BMI (r= -0.38, p = p-0.14). Although gender differences in upper body strength are expected, handgrip strength is within the gender-specific average range of the general population. The integration of anthropometric characteristics and upper body strength when prescribing exercise must be considered since these factors influence functional capacity and quality of life among HIV+ adults

Ciencia sobre ruedas en Granada. Una experiencia de actualización científica y tecnológica en el aula

Describimos una experiencia de colaboración entre el Parque de las Ciencias de Granada y el centro educativo Ciencias sobre Ruedas de Puerto Rico para llevar a siete centros educativos de Andalucía la tecnología de experimentación asistida por ordenador, EXAO, conectándola con temas de investigación real en el área de química. El proceso comenzó con la formación del profesorado en el uso de esta tecnología dentro de un enfoque de enseñanza orientado hacia la investigación en el aula. La actividad ha estado a cargo de profesores universitarios de Puerto Rico que desarrollan actualmente sus investigaciones de doctorado. Se ofrece la experiencia como un modelo de actualización y formación del profesorado no universitario de ciencias

Bimodal microwave and ultrasound phantoms for non-invasive clinical imaging

A precise and thorough methodology is presented for the design and fabrication of bimodal phantoms to be used in medical microwave and ultrasound applications. Dielectric and acoustic properties of human soft tissues were simultaneously mimicked. The phantoms were fabricated using polyvinyl alcohol cryogel (PVA-C) as gelling agent at a 10% concentration. Sucrose was employed to control the dielectric properties in the microwave spectrum, whereas cellulose was used as acoustic scatterer for ultrasound. For the dielectric properties at microwaves, a mathematical model was extracted to calculate the complex permittivity of the desired mimicked tissues in the frequency range from 500 MHz to 20 GHz. This model, dependent on frequency and sucrose concentration, was in good agreement with the reference Cole-Cole model. Regarding the acoustic properties, the speed of sound and attenuation coefficient were employed for validation. In both cases, the experimental data were consistent with the corresponding theoretical values for soft tissues. The characterization of these PVA-C phantoms demonstrated a significant performance for simultaneous microwave and ultrasound operation. In conclusion, PVA-C has been validated as gelling agent for the fabrication of complex multimodal phantoms that mimic soft tissues providing a unique tool to be used in a range of clinical applications.Tis work was supported by the IACTEC Technological Training program (TF INNOVA 2016-2021) and European Union Interreg-Mac funding program under grant MAC/1.1.b/098 (MACbioIDi project). Te authors would like to thank the Medical Technology for Sustainable Development from the Instituto Universitario de Investigación Biomédica y Sanitaria (IUIBS), Universidad de Las Palmas de Gran Canaria, for the loan of US equipment

Adapting a Family-Focused Diabetes Prevention Program for a Federally Qualified Health Center: A Qualitative Report

Purpose The purpose of the study was to explore the needs of high-risk Latinx/Hispanic women with a history of gestational diabetes who were patients at a Federally Qualified Health Center (FQHC) in anticipation of a future family-based program. Methods Six focus group studies were conducted in partnership with El Rio Community Health Center, an FQHC in Tucson, Arizona. Thirty-nine women participated, each identified as Latinx/Hispanic, self-reported a history of gestational diabetes or prediabetes, and had at least 1 child aged 8 to 13. Three investigators independently reviewed transcripts from the focus groups to identify themes that reflected thematic saturation from participants' responses. Data coding and results were discussed as a group and any differences were collectively adjudicated. Results All participants had a family member with diabetes and worried about their and their immediate family members' risk for developing the disease. The possible benefits of participating in a lifestyle prevention program were universally recognized, but multiple barriers to participation were described, including scheduling conflicts, access to childcare, transportation, and the need to involve additional family members to reinforce program objectives. Conclusions There is a strong willingness to participate in a diabetes prevention program among respondents, but to be successful, interventions must be tailored to specific needs and challenges. Trying to apply existing prevention curricula with low-income Latinx/Hispanic populations may not be successful without adaptations.This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Orthotropic Piezoelectricity in 2D Nanocellulose

The control of electromechanical responses within bonding regions is essential to face frontier challenges in nanotechnologies, such as molecular electronics and biotechnology. Here, we present I\b{eta}-nanocellulose as a potentially new orthotropic 2D piezoelectric crystal. The predicted in-layer piezoelectricity is originated on a sui-generis hydrogen bonds pattern. Upon this fact and by using a combination of ab-initio and ad-hoc models, we introduce a description of electrical profiles along chemical bonds. Such developments lead to obtain a rationale for modelling the extended piezoelectric effect originated within bond scales. The order of magnitude estimated for the 2D I\b{eta}-nanocellulose piezoelectric response, ~pm V-1, ranks this material at the level of currently used piezoelectric energy generators and new artificial 2D designs. Such finding would be crucial for developing alternative materials to drive emerging nanotechnologies.Comment: 5 figures included. Supp. Mat. available on the online version: https://www.nature.com/articles/srep34616, Others on: http://www.nanowerk.com/nanotechnology-news/newsid=44806.ph

Características de la actividad física para la mejora de la salud y la calidad de vida de las personas mayores según los profesionales y los usuarios

The objective of this research was to compare the opinions of the persons in charge of carrying out the physical exercise activities which focus in the improvement of health and life quality of the elderly, with the users to whom it is intended. The sample was composed of 45 people (23 women and 22 men) with a mean age of 30.15 years (± 6.49) who are responsible for physical and sports activities for the elderly in day care centers and residences that depends on the Institute of Social and Health Care Council of Gran Canaria and the Canarias Islands Government and also in the municipal activities in any of the municipalities of the island of Gran Canaria. Regarding users, we psurveyed a total of 111 people, aged between 57 and 76, participants of the program Peritia et Doctrine of the University of Las Palmas. For information on the type of activity they performed, part of the questionnaire that would address issues like content, planning methodology was developed and some specific other characteristic. The way to ask the question and the answer was based on the Likert scale. The results lead us to conclude that people in charge of both physical and sporting activity as well as users have a similar perception of the needs and characteristics of content, planning and specific characteristics. Nevertheless, they differ in the importance given to the methodology of such activities.El objetivo de esta investigación ha sido comparar las opiniones de las personas encargadas de la realización de las actividades de ejercicio físico centrado en la mejora de la salud y la calidad de vida de las personas mayores, con las de los usuarios a las que va destinada. La muestra se basó en 45 personas que se encargan de las actividades físicas y deportivas para personas mayores en los centros de día y residencias que dependen del Instituto de Atención Sociosanitaria del Cabildo de Gran Canaria y del Gobierno de Canarias en Gran Canaria y, en las actividades municipales realizadas en alguno de los municipios de la isla de Gran Canaria (23 mujeres y 22 hombres) y, con edad media de 30.15 años (±6.49). Respecto a los usuarios, encuestamos a un número total de 111 personas, con edades comprendidas entre 57 y 76 años, participantes en el programa formativo especial Peritia et Doctrina de la Universidad de Las Palmas de Gran Canaria. Palabras claves. Para obtener información del tipo de actividad que realizan los encuestados, se elaboró una parte del cuestionario que abordara temas de contenidos, planificación, metodología y alguna que otra característica específica. La forma de plantear la pregunta y la respuesta se basó en la escala tipo Likert. Los resultados obtenidos nos llevan a concluir que tanto las personas encargadas de la actividad física y deportivas como los usuarios tienen una percepción similar de las necesidades y características de los contenidos, planificación y las características específicas. Si bien difieren en la importancia que le dan a la metodología de dichas actividades

Morphological foot model for temperature pattern analysis proposed for diabetic foot disorders

Infrared thermography is a non-invasive and accessible tool that maps the surface temperature of a body. This technology is particularly useful for diabetic foot disorders, since it facilitates the identification of higher risk patients by frequent monitoring and therefore limits the incidence of disabling conditions. The aim of this work is to provide a methodology to explore the entire plantar aspects of both feet, based on infrared thermography, for the assessment of diabetic foot anomalies. A non-invasive methodology was established to identify areas of higher risk and track their progress via longitudinal monitoring. A standard morphological model was extracted from a group of healthy subjects, nine females and 13 males, by spatial image registration. This healthy foot model can be taken as a template for the assessment of temperature asymmetry, even in cases in which partial amputations or deformations are present. A pixel-wise comparison of the temperature patterns was carried out by Wilcoxon´s matched-pairs test using the corresponding template. For all the subjects, the left foot was compared to the contralateral foot, the right one, providing a map of statistically significant areas of variation, within the template, among the healthy subjects at different time points. In the female case, the main areas of variability were the boundaries of the feet, whereas for the male, in addition to this, substantial changes that exhibited a clear pattern were observed. A fast and simple monitoring tool is provided to be used for personalized medical diagnosis in patients affected by diabetic foot disorders.This research was funded by the IACTEC Technological Training program, grant number TF INNOVA 2016-2021. This work was completed while Abián Hernández was a beneficiary of a pre-doctoral grant given by the “Agencia Canaria de Investigacion, Innovacion y Sociedad de la Información (ACIISI)” of the “Consejería de Economía, Conocimiento y Empleo” of the “Gobierno de Canarias”, which is partly financed by the European Social Fund (FSE) (POC 2014-2020, Eje 3 Tema Prioritario 74 (85%))

A distal to proximal gradient of human choroid plexus development, with antagonistic expression of Glut1 and AQP1 in mature cells vs. calbindin and PCNA in proliferative cells

The choroid plexuses (ChP) are highly vascularized tissues suspended from each of the cerebral ventricles. Their main function is to secret CSF that fills the ventricles and the subarachnoid spaces, forming a crucial system for the development and maintenance of the CNS. However, despite the essential role of the ChP–CSF system to regulate the CNS in a global manner, it still remains one of the most understudied areas in neurobiology. Here we define by immunohistochemistry the expression of different proteins involved in the maturation and functionality of the ChP from the late embryological period to maturity. We found an opposite gradient of expression between AQP1 and Glut1 that define functional maturation in the ChP periphery, and PCNA and calbindin, present in the ChP roof zone with proliferative activity. We conclude that the maturation of the ChP matures from distal to proximal, starting in the areas nearest to the cortex, expressing in the distal, mature areas AQP1 and Glut1 (related to ChP functionality to support cortex development), and in the proximal immature areas (ChP root) calbindin and PCNA related to progenitor activity and proliferation