4,305 research outputs found

    Towards a shared method to classify contaminated territories in the case of an accidental nuclear event: the PRIME project

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    The analysis of the management of the accidentally radioactive contaminated areas such as those around Chernobyl nuclear power plant highlights the fact that the current spatial classification methods hardly help in recovering proper use of the contaminated territory. The cause is mainly to be searched for in the traditional construction of risks assessment methods; these methods rest on criteria defined by institutional experts, which are not applicable in practise because they are not shared by all the stakeholders involved in the management of the contaminated territories. Opposite such top-down tentative management, local efforts supported by Non-Governmental Organizations to restore life in the contaminated area seem to be more fruitful but very time and resources consuming and limited to the specific areas where they are experimented. The aim of the PRIME project, in progress at the French Institute for Radioprotection and Nuclear Safety, is to mix the advantages of both approaches in building a multicriteria decision tool based on the territorial specificities. The criteria of the method are chosen and weighted with representatives of the territory’s stakeholders (decision makers, local actors and experts) to warrant that all the points of view are taken into account and to enable the risk managers to choose the appropriate strategy in case of an accident involving radioactive substances. The area chosen for the pilot study is a 50 km radius territory around the nuclear sites of Tricastin-Pierrelatte in the lower valley of Rhône (France). One of the exploration questions of the PRIME project is whether a multicriteria method may be an appropriate tool to treat the data and make them visible and accessible for all the stakeholders

    Real time decoherence of Landau and Levitov quasi-particles in quantum Hall edge channels

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    Quantum Hall edge channels at integer filling factor provide a unique test-bench to understand decoherence and relaxation of single electronic excitations in a ballistic quantum conductor. In this Letter, we obtain a full visualization of the decoherence scenario of energy (Landau) and time (Levitov) resolved single electron excitations at filling factor ν=2\nu=2. We show that the Landau excitation exhibits a fast relaxation followed by spin-charge separation whereas the Levitov excitation only experiences spin-charge separation. We finally suggest to use Hong-Ou-Mandel type experiments to probe specific signatures of these different scenarios.Comment: 14 pages, 8 figure

    Oxidative phosphorylation efficiency, proton conductance and reactive oxygen species production of liver mitochondria correlates with body mass in frogs

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    ody size is a central biological parameter affecting most biological processes (especially energetics) and mitochondria is a key organelle controlling metabolism and is also the cell's main source of chemical energy. However, the link between body size and mitochondrial function is still unclear, especially in ectotherms. In this study, we investigated several parameters of mitochondrial bioenergetics in the liver of three closely related species of frogs (the common frog Rana temporaria, the marsh frog Pelophylax ridibundus and the bull frog Lithobates catesbeiana). These particular species were chosen due to their differences in adult body mass. We found that the mitochondrial coupling efficiency was markedly increased with animal size, which lead to a higher ATP production (+70%) in the larger frogs (L. catesbeiana) compared to the smaller frogs (R. temporaria). This was essentially driven by a strong negative dependence of mitochondrial proton conductance on body mass. Liver mitochondria from the larger frogs (L. catesbeiana) displayed 50% of the proton conductance of mitochondria from the smaller frogs (R. temporaria). Contrary to our prediction, the low mitochondrial proton conductance measured in L. catesbeiana was not associated with higher radical oxygen species production. Instead, liver mitochondria from the larger individuals produced significantly lower radical oxygen species than those from the smaller frogs. Collectively, the data shows that key bioenergetics parameters of mitochondria (proton leak, ATP production efficiency and radical oxygen species production) are correlated with body mass in frogs. This research expands our understanding of the relationship between mitochondrial function and the evolution of allometric scaling in ectotherms

    Scanamorphos: a map-making software for Herschel and similar scanning bolometer arrays

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    Scanamorphos is one of the public softwares available to post-process scan observations performed with the Herschel photometer arrays. This post-processing mainly consists in subtracting the total low-frequency noise (both its thermal and non-thermal components), masking high-frequency artefacts such as cosmic ray hits, and projecting the data onto a map. Although it was developed for Herschel, it is also applicable with minimal adjustment to scan observations made with some other imaging arrays subjected to low-frequency noise, provided they entail sufficient redundancy; it was successfully applied to P-Artemis, an instrument operating on the APEX telescope. Contrary to matrix-inversion softwares and high-pass filters, Scanamorphos does not assume any particular noise model, and does not apply any Fourier-space filtering to the data, but is an empirical tool using purely the redundancy built in the observations -- taking advantage of the fact that each portion of the sky is sampled at multiple times by multiple bolometers. It is an interactive software in the sense that the user is allowed to optionally visualize and control results at each intermediate step, but the processing is fully automated. This paper describes the principles and algorithm of Scanamorphos and presents several examples of application.Comment: This is the final version as accepted by PASP (on July 27, 2013). A copy with much better-quality figures is available on http://www2.iap.fr/users/roussel/herschel

    The effect of maternal iron deficiency on zinc and copper levels and on genes of zinc and copper metabolism during pregnancy in the rat

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    Fe deficiency is relatively common in pregnancy and has both short- and long-term consequences. However, little is known about the effect on the metabolism of other micronutrients. A total of fifty-four female rats were fed control (50 mg Fe/kg) or Fe-deficient diets (7·5 mg/kg) before and during pregnancy. Maternal liver, placenta and fetal liver were collected at day 21 of pregnancy for Cu and Zn analysis and to measure expression of the major genes of Cu and Zn metabolism. Cu levels increased in the maternal liver (P=0·002) and placenta (P=0·018) of Fe-deficient rats. Zn increased (P&lt;0·0001) and Cu decreased (P=0·006) in the fetal liver. Hepatic expression of the Cu chaperones antioxidant 1 Cu chaperone (P=0·042) and cytochrome c oxidase Cu chaperone (COX17, P=0·020) decreased in the Fe-deficient dams, while the expression of the genes of Zn metabolism was unaltered. In the placenta, Fe deficiency reduced the expression of the chaperone for superoxide dismutase 1, Cu chaperone for superoxide dismutase (P=0·030), ceruloplasmin (P=0·042) and Zn transport genes, ZRT/IRT-like protein 4 (ZIP4, P=0·047) and Zn transporter 1 (ZnT1, P=0·012). In fetal liver, Fe deficiency increased COX17 (P=0·020), ZRT/IRT-like protein 14 (P=0·036) and ZnT1 (P=0·0003) and decreased ZIP4 (P=0·004). The results demonstrate that Fe deficiency during pregnancy has opposite effects on Cu and Zn levels in the fetal liver. This may, in turn, alter metabolism of these nutrients, with consequences for development in the fetus and the neonate.</p

    High-resolution Elemental Mapping of the Lunar Surface

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    New instruments and missions are being proposed to study the lunar surface as a result of the resurgence of interest in returning to the Moon. One instrument recently proposed is similar in concept to the x-ray fluorescence detectors flown on Apollo, but utilizes fluorescence from the L- and M-shells rather than the K-shell. This soft X-Ray Flourescence Imager (XRFI) is discussed

    Acid/base-triggered switching of circularly polarized luminescence and electronic circular dichroism in organic and organometallic helicenes.

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    Electronic circular dichroism and circularly polarized luminescence acid/base switching activity has been demonstrated in helicene-bipyridine proligand 1 a and in its “rollover” cycloplatinated derivative 2 a. Whereas proligand 1 a displays a strong bathochromic shift (>160 nm) of the nonpolarized and circularly polarized luminescence upon protonation, complex 2 a displays slightly stronger emission. This strikingly different behavior between singlet emission in the organic helicene and triplet emission in the organometallic derivative has been rationalized by using quantum-chemical calculations. The very large bathochromic shift of the emission observed upon protonation of azahelicene-bipyridine 1 a has been attributed to the decrease in aromaticity (promoting a charge-transfer-type transition rather than a π–π* transition) as well as an increase in the HOMO–LUMO character of the transition and stabilization of the LUMO level upon protonation

    SPIRE Map-Making Test Report

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    The photometer section of SPIRE is one of the key instruments on board of Herschel. Its legacy depends very much on how well the scanmap observations that it carried out during the Herschel mission can be converted to high quality maps. In order to have a comprehensive assessment on the current status of SPIRE map-making, as well as to provide guidance for future development of the SPIRE scan-map data reduction pipeline, we carried out a test campaign on SPIRE map-making. In this report, we present results of the tests in this campaign.Comment: This document has an executive summary, 6 chapters, and 102 pages. More information can be found at: https://nhscsci.ipac.caltech.edu/sc/index.php/Spire/SPIREMap-MakingTest201
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