The Great Background in Hardy and Lawrence

This thesis investigates D.H. Lawrence’s idea of the “great background” in the context of Thomas Hardy’s Jude the Obscure and how it reappears in a transformed way in Lawrence’s novels Sons and Lovers, The Rainbow, and Women in Love. Through examining the perverse effects of modernism on these novels’ characters, this thesis argues that the “great background” is something that gradually moves inward––from the old, traditional “State” to an internal, inscrutable yet attainable reality

An Improved Approach To Watercolor Reproduction By Profile Editing

Fine art is usually produced on paper or canvas as a one-of-a-kind artwork. Fine art may be reproduced in limited editions and put up for sale as art. Different printing technologies have been used in fine art reproduction such as lithography, screenprinting, and most recently inkjet. The research aspect of watercolor reproduction has been the question of how good is good enough. In this case, the artists demand the exact match between the original watercolor and its reproduction. While there are difficulties in quantifying the degree of color image match, the initial testing of watercolor reproduction using a colormanaged approach with an inkjet printer showed that there is a need to improve the reproduction quality. The objective of this study is to see if accuracy of watercolor reproduction can be improved by using profile editing tools. The significance of the research is the potential to achieve higher reproduction quality in watercolor by means of profile editing. In addition, we can put control back in the hands of content creators for limited editions. This research begins with a literature review. The review discusses how artworks are being digitized and reproduced by museums. It points out the wide adoption of International Color Consortium (ICC) color management practices in printing and publishing. It also covers how a color image match between an original and its reproduction is assessed quantitatively and qualitatively. The quantitative analyses of Macbeth ColorChecker between a generic ICC profile and a custom ICC profile were used to test first hypothesis, i.e., if there is any significant difference in measured color accuracy of watercolor reproductions between a generic ICC profile and a custom ICC profile. The results indicate that there is a significant difference in color accuracy of watercolor reproduction between using generic ICC profile and the custom ICC profile state findings. To our surprise, the custom ICC profile performed worse than the generic ICC profile. A possible cause of the large color differences was attributed to the accuracy of the scanner profile. A paired comparison method was used to test the second hypothesis, i.e., if there is any significant visual difference in color accuracy of watercolor reproductions between an unedited ICC profile and an edited ICC profile. The results indicate that there is no significant difference in color accuracy of watercolor reproduction between an unedited ICC profile and an edited ICC profile state findings. To our surprise once again, edited profiles did not perform color matching any better than unedited profiles. A major factor is that editing of tone reproduction and gray balance are treated as two separate events in the profile editing process. In fact, tone reproduction and gray balance are dependent on each other

Preparation of hexagonal GeO2 particles with particle size and crystallinity controlled by peptides, silk and silk-peptide chimeras

We demonstrate the use of silk based proteins to control the particle/crystallite size during GeO2 formation, using a bio-mimetic approach at circumneutral pH and ambient temperature. Multicrystalline GeO2 was prepared from germanium tetraethoxide (TEOG) in the presence of different silk-based proteins: Bombyx mori silk (native silk) and two chimeric proteins prepared by linking a germania binding peptide (Ge28: HATGTHGLSLSH) with Bombyx mori silk via chemical coupling at different peptide loadings (silk-Ge28 10% and silk-Ge28 50%). The mineralisation activity of the silk-based proteins was compared with that of peptide Ge28 as a control system. GeO2 mineralisation was investigated in water and in citric acid/bis-tris propane buffer at pH 6. Morphology, particle size, crystallinity, water and organic content of the materials obtained were analysed to study the effect of added biomolecules and mineralisation environment on material properties. In the presence of silk additives well-defined cube-shape hybrid materials composed of hexagonal germania and up to ca. 5 wt% organic content were obtained. The cubic particles ranged from 0.4 to 1.4m in size and were composed of crystalline domains in the range 35-106 nm depending on the additive used and synthesis conditions

A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions

Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings. The most potent and selective A–C estrogen is selective for activating ER relative to seven other nuclear hormone receptors, with a surprising 750-fold selectivity for the β over α isoform and with EC50s of 20–30 nM in cell-based and direct binding assays. Comparison of potency in different assays suggests that the ER isoform selectivity is related to the compound’s ability to drive the productive conformational change needed to activate transcription. The compound also shows in vivo efficacy after microinfusion into the dorsal hippocampus and after intraperitoneal injection (0.5 mg/kg) or oral gavage (0.5 mg/kg). This simple yet novel A–C estrogen is selective, brain penetrant, and facilitates memory consolidation

Puget Sound Dissolved Oxygen Modeling Study: Development of an Intermediate-Scale Hydrodynamic Model

The Washington State Department of Ecology contracted with Pacific Northwest National Laboratory to develop an intermediate-scale hydrodynamic and water quality model to study dissolved oxygen and nutrient dynamics in Puget Sound and to help define potential Puget Sound-wide nutrient management strategies and decisions. Specifically, the project is expected to help determine 1) if current and potential future nitrogen loadings from point and non-point sources are significantly impairing water quality at a large scale and 2) what level of nutrient reductions are necessary to reduce or dominate human impacts to dissolved oxygen levels in the sensitive areas. In this study, an intermediate-scale hydrodynamic model of Puget Sound was developed to simulate the hydrodynamics of Puget Sound and the Northwest Straits for the year 2006. The model was constructed using the unstructured Finite Volume Coastal Ocean Model. The overall model grid resolution within Puget Sound in its present configuration is about 880 m. The model was driven by tides, river inflows, and meteorological forcing (wind and net heat flux) and simulated tidal circulations, temperature, and salinity distributions in Puget Sound. The model was validated against observed data of water surface elevation, velocity, temperature, and salinity at various stations within the study domain. Model validation indicated that the model simulates tidal elevations and currents in Puget Sound well and reproduces the general patterns of the temperature and salinity distributions

What can veterinary professionals do? Measuring the effect of one domestic violence training pilot program on veterinary professionals' capacity to recognize, respond, and refer human victims of domestic violence

IntroductionVeterinary professionals have a key role in facilitating multi-agency collaboration to prevent and respond to domestic violence (DV) in situations where animals may be directly or indirectly involved. Yet despite their position as potential touchpoints for victim-survivors with animals, many veterinary professionals do not feel equipped to act on suspicions or disclosures of DV. In response to this identified need, one service operating in Melbourne, Australia, developed the Vet-3R's training program (Recognize-Respond-Refer) which was piloted on 65 veterinary professionals in Melbourne's Eastern Metropolitan Region.MethodsThis is an exploratory study aimed at measuring the effect of the Vets 3-R's program on veterinary professionals' confidence and capacity to recognize, respond and refer victims of DV. Participants were invited to complete online surveys before and after the training to evaluate their understanding of DV and their capacity to support suspected victim-survivors with animals who present at their service.ResultsThe pre-training self-evaluation scores indicated that while most veterinary professionals are aware of the link between animal abuse and DV, they lack the confidence to respond and refer individuals when confronted with suspicions or disclosures of abuse. However, upon completion of the Vets 3-R's program, participants reported marked improvements in their ability to recognize, respond, and refer victim-survivors. The most significant improvement could be seen in participants' self-reported ability to respond appropriately to suspicions of DV.DiscussionWhile results are indicative only due to the small sample size, this study suggests that veterinary professionals may be an underutilized intervention point for DV victim-survivors with animals. The Vet-3R's training program can be a useful tool for increasing effectiveness of this intervention point to safely assist DV victim-survivors. More research on similar programs with a larger cohort of participants would be beneficial to measure the impact of such programs on a wider scale

Solar Effects on Tensile and Optical Properties of Hubble Space Telescope Silver-Teflon(Registered Trademark) Insulation

A section of the retrieved Hubble Space Telescope (HST) solar array drive arm (SADA) multilayer insulation (MLI), which experienced 8.25 years of space exposure, was analyzed for environmental durability of the top layer of silver-Teflon (DuPont) fluorinated ethylene propylene (Ag-FEP). Because the SADA MLI had solar and anti-solar facing surfaces and was exposed to the space environment for a long duration, it provided a unique opportunity to study solar effects on the environmental degradation of Ag-FEP, a commonly used spacecraft thermal control material. Data obtained included tensile properties, solar absorptance, surface morphology and chemistry. The solar facing surface was found to be extremely embrittled and contained numerous through-thickness cracks. Tensile testing indicated that the solar facing surface lost 60% of its mechanical strength and 90% of its elasticity while the anti-solar facing surface had ductility similar to pristine FEP. The solar absorptance of both the solar facing surface (0.155 plus or minus 0.032) and the anti-solar facing surface (0.208 plus or minus 0.012) were found to be greater than pristine Ag-FEP (0.074). Solar facing and anti-solar facing surfaces were microscopically textured, and locations of isolated contamination were present on the anti-solar surface resulting in increased localized texturing. Yet, the overall texture was significantly more pronounced on the solar facing surface indicating a synergistic effect of combined solar exposure and increased heating with atomic oxygen erosion. The results indicate a very strong dependence of degradation, particularly embrittlement, upon solar exposure with orbital thermal cycling having a significant effect