1,179 research outputs found

    Limb reconstruction in Ollier's disease.

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    We present our experience of lengthening and correction of complex deformities in the management of patients with Ollier's dysplasia (multiple enchondromatosis) from 1985 and 2002. All patients were under 18 years with a minimum follow-up time of 2 years (mean 9.6 years, range 2-15 years). There were a total of ten patients of which seven were male and three female. The mean age at presentation was 10.7 years (range 5-17 years; SD 3.7 years). The total length gain was 42.3 mm (range 30-110 mm; SD 28.9 mm). The number of days in external fixation was 164.8 days (range 76-244 days; SD 42.9 days). The bone healing index was 32.5 days/cm (18-50 days/cm; SD 10.3 days/cm). Patients with Ollier's disease have limb length inequality and angular deformities and require multiple reconstructive procedures owing to a high incidence of recurrence. We identified a tendency for the osteotomy to prematurely consolidate and advise the latency period after surgery to be 4-5 days and for distraction to proceed at a faster rate

    In situ light dosimetry during photodynamic therapy of Barrett's esophagus with 5-aminolevulinic acid

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    Background and Objectives: Previous studies with PhotoDynamic Therapy (PDT) in bladder and bronchi have shown that due to scattering and reflection, the actually delivered fluence rate on the surface in a hollow organ can be significantly higher than expected. In this pilot study, we investigated the differences between the primary calculated and the actual measured fluence rate during PDT of Barrett's Esophagus (BE) using 23 independent clinical measurements in 15 patients. Study Design/Materials and Methods: A KTP-dye module laser at 630 nm was used as light source. Light delivery was performed using a cylindrical light diffuser inserted in the center of an inflatable transparent balloon with a length corresponding to the length of the Barrett's epithelium. The total light output power of the cylindrical diffuser was calibrated using an integrating sphere to deliver a primary fluence rate of 100 mW cm-2. Two fiber-optic pseudo sphere isotropic detectors were placed on the balloon and were used to measure fluence rate at the surface of the esophageal wall during PDT. Results and Conclusions: The actual fluence rate measured was 1.5-3.9 times higher than the primary fluence rate for 630 nm. In general, the fluence rate amplification factor decreased with increasing redness of the tissue and was less for shorter diffusers. Fluence rate variations in time were observed which coincided with patients coughing, movement, and esophageal spasms. These factors combined with inter patient variability of the fluence rate measured appears to justify the routine application of this technique in PDT of BE

    Signatures of Primordial non-Gaussianities in the Matter Power-Spectrum and Bispectrum: the Time-RG Approach

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    We apply the time-renormalization group approach to study the effect of primordial non-Gaussianities in the non-linear evolution of cosmological dark matter density perturbations. This method improves the standard perturbation approach by solving renormalization group-like equations governing the dynamics of gravitational instability. The primordial bispectra constructed from the dark matter density contrast and the velocity fields represent initial conditions for the renormalization group flow. We consider local, equilateral and folded shapes for the initial non-Gaussianity and analyze as well the case in which the non-linear parameter f_{NL} parametrizing the strength of the non-Gaussianity depends on the momenta in Fourier space through a power-law relation, the so-called running non-Gaussianity. For the local model of non-Gaussianity we compare our findings for the power-spectrum with those of recent N-body simulations and find that they accurately fit the N-body data up to wave-numbers k \sim 0.25 h/Mpc at z=0. We also present predictions for the (reduced) matter bispectra for the various shapes of non-Gaussianity.Comment: 27 pages, 12 figures. Results and discussion for a particular case added. One figure and one reference added. Matches with the version accepted for publication in the JCAP

    From Majorana theory of atomic autoionization to Feshbach resonances in high temperature superconductors

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    The Ettore Majorana paper - Theory of incomplete P triplets- published in 1931, focuses on the role of selection rules for the non-radiative decay of two electron excitations in atomic spectra, involving the configuration interaction between discrete and continuum channels. This work is a key step for understanding the 1935 work of Ugo Fano on the asymmetric lineshape of two electron excitations and the 1958 Herman Feshbach paper on the shape resonances in nuclear scattering arising from configuration interaction between many different scattering channels. The Feshbach resonances are today of high scientific interest in many different fields and in particular for ultracold gases and high Tc superconductivity.Comment: 13 pages, 7 figures. Journal of Superconductivity and Novel Magnetism to be publishe

    Chaos in a double driven dissipative nonlinear oscillator

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    We propose an anharmonic oscillator driven by two periodic forces of different frequencies as a new time-dependent model for investigating quantum dissipative chaos. Our analysis is done in the frame of statistical ensemble of quantum trajectories in quantum state diffusion approach. Quantum dynamical manifestation of chaotic behavior, including the emergence of chaos, properties of strange attractors, and quantum entanglement are studied by numerical simulation of ensemble averaged Wigner function and von Neumann entropy.Comment: 9 pages, 18 figure

    Ultrarelativistic black hole in an external electromagnetic field and gravitational waves in the Melvin universe

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    We investigate the ultrarelativistic boost of a Schwarzschild black hole immersed in an external electromagnetic field, described by an exact solution of the Einstein-Maxwell equations found by Ernst (the ``Schwarzschild-Melvin'' metric). Following the classical method of Aichelburg and Sexl, the gravitational field generated by a black hole moving ``with the speed of light'' and the transformed electromagnetic field are determined. The corresponding exact solution describes an impulsive gravitational wave propagating in the static, cylindrically symmetric, electrovac universe of Melvin, and for a vanishing electromagnetic field it reduces to the well known Aichelburg-Sexl pp-wave. In the boosting process, the original Petrov type I of the Schwarzschild-Melvin solution simplifies to the type II on the impulse, and to the type D elsewhere. The geometry of the wave front is studied, in particular its non-constant Gauss curvature. In addition, a more general class of impulsive waves in the Melvin universe is constructed by means of a six-dimensional embedding formalism adapted to the background. A coordinate system is also presented in which all the impulsive metrics take a continuous form. Finally, it is shown that these solutions are a limiting case of a family of exact gravitational waves with an arbitrary profile. This family is identified with a solution previously found by Garfinkle and Melvin. We thus complement their analysis, in particular demonstrating that such spacetimes are of type II and belong to the Kundt class.Comment: 11 pages, REVTeX
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