Mechanisms of change in cognitive-behavioral therapy in relation to depressives' dysfunctional thoughts

This dissertation examined the therapeutic components within Beck's cognitive-behavioral treatment in relation to changes in global measures of depression and in specific response classes relevant to depression. Furthermore, the dissertation noted which response classes were influenced by each component and attempted to predict responsiveness to components by subject classification on frequency of dysfunctional thoughts. Thirty-seven moderately to severely depressed subjects participated in cognitive-behavioral group therapy. Beck's treatment was divided into the following components: self-monitoring dysfunctional thoughts (Component A), logical analysis (Component B), and hypothesis testing (Component C). To control for order effects, half the subjects were exposed to the components in the sequence ABC and half to the sequence ACB. Using initial frequency scores from the Automatic Thoughts Questionnaire, subjects were divided into two subtypes--those with a high versus a low frequency of dysfunctional thoughts

Head Start Programs: Are They Beneficial to Low-Income, African American Children? An Ethnographic Analysis of School Readiness

Understanding how head start programs are preparing low income African American children to successfully transition from preschool to kindergarten is important. However, the long term effectiveness of these programs on childrens academic abilities is currently being debated. Therefore, we used an interpretive qualitative approach, guided by resiliency theory, to explore the lives of ten families from an improvised Midwestern neighborhood in an effort to better understand how their head start program was preparing their children for the transition to kindergarten. During two in-depth interviews, one conducted with mothers while their child was enrolled in pre-kindergarten, and one following their childs completion of kindergarten, we asked mothers to rate their childs preparedness for kindergarten. The following three categories emerged: 1) children whos before and after kindergarten preparedness scores increased, 2) children whos before and after kindergarten preparedness scores remained the same, and 3) children whos before and after kindergarten preparedness scores decreased. Five children had an increased in their scores, demonstrating that they exceeded their kindergarten teachers expectations. Four children had consistent scores, demonstrating they met their teachers expectations. Only one child had a decrease in their scores, demonstrating that they struggled to meet their teachers expectations. Based on these findings, we conclude that for the majority of our participants, head start was successful in preparing them for their transition from preschool to kindergarten. This is important because it highlights the significance of head start programs in effectively placing children on the right path for academic success.Ope

“I write my letters at school, so I’m ready right?” Low-income Latino children’s transition from preschool to kindergarten

The transition to kindergarten is a significant period in children’s education that initiates the development of skills that promote future academic success. Studies indicate that Latino children in the United States are disproportionately disadvantaged during this critical period of development, and are most likely to fall below the recommended level of kindergarten readiness. Researchers report that Latina mothers often have different beliefs and perceptions of school readiness and parental involvement, but little is known about the preparatory practices of low- income suburban Latina mothers before children enter kindergarten. This study used qualitative interviews to better understand the factors that influence Latino children’s kindergarten readiness and how low-income Latina mothers (N = 17) engage in their children’s educational development as they transition to kindergarten. Latina mothers reported understanding kindergarten readiness in terms of nominal knowledge and emergent literacy skills. When asked about parental involvement practices, mothers reported home-based involvement focusing on socialization rather than school-based involvement focusing on academics. The mothers in this study also reported being actively involved in their children’s kindergarten preparation, engaging in various activities that promote children’s readiness. Barriers to parental involvement were also noted, and included language barriers and busy work schedules. These findings contribute to our understanding of school readiness practices, and parental involvement within low-income Latino families during the transition from preschool to kindergarten.USDA Institute of Food and Agriculture Hatch Project 793-357 [accession number: 1007545]Ope

Initial severity of depression and efficacy of cognitive-behavioural therapy: individual-participant data meta-analysis of pill-placebo-controlled trials

BACKGROUND: The influence of baseline severity has been examined for antidepressant medications but has not been studied properly for cognitive-behavioural therapy (CBT) in comparison with pill placebo. AIMS: To synthesise evidence regarding the influence of initial severity on efficacy of CBT from all randomised controlled trials (RCTs) in which CBT, in face-to-face individual or group format, was compared with pill-placebo control in adults with major depression. METHOD: A systematic review and an individual-participant data meta-analysis using mixed models that included trial effects as random effects. We used multiple imputation to handle missing data. RESULTS: We identified five RCTs, and we were given access to individual-level data (n = 509) for all five. The analyses revealed that the difference in changes in Hamilton Rating Scale for Depression between CBT and pill placebo was not influenced by baseline severity (interaction P = 0.43). Removing the non-significant interaction term from the model, the difference between CBT and pill placebo was a standardised mean difference of -0.22 (95% CI -0.42 to -0.02, P = 0.03, I2 = 0%). CONCLUSIONS: Patients suffering from major depression can expect as much benefit from CBT across the wide range of baseline severity. This finding can help inform individualised treatment decisions by patients and their clinicians.R01 MH060998 - NIMH NIH HHS; R34 MH086668 - NIMH NIH HHS; R01 AT007257 - NCCIH NIH HHS; R21 MH101567 - NIMH NIH HHS; K02 MH001697 - NIMH NIH HHS; R01 MH060713 - NIMH NIH HHS; R34 MH099311 - NIMH NIH HHS; R21 MH102646 - NIMH NIH HHS; K23 MH100259 - NIMH NIH HHS; R01 MH099021 - NIMH NIH HH

Recent Trends in Local-Scale Marine Biodiversity Reflect Community Structure and Human Impacts

The modern biodiversity crisis reflects global extinctions and local introductions. Human activities have dramatically altered rates and scales of processes that regulate biodiversity at local scales [1-7]. Reconciling the threat of global biodiversity loss [2, 4, 6-9] with recent evidence of stability at fine spatial scales [10,11] is a major challenge and requires a nuanced approach to biodiversity change that integrates ecological understanding. With a new dataset of 471 diversity time series spanning from 1962 to 2015 from marine coastal ecosystems, we tested (1) whether biodiversity changed at local scales in recent decades, and (2) whether we can ignore ecological context (e.g., proximate human impacts, trophic level, spatial scale) and still make informative inferences regarding local change. We detected a predominant signal of increasing species richness in coastal systems since 1962 in our dataset, though net species loss was associated with localized effects of anthropogenic impacts. Our geographically extensive dataset is unlikely to be a random sample of marine coastal habitats; impacted sites (3% of our time series) were underrepresented relative to their global presence. These local-scale patterns do not contradict the prospect of accelerating global extinctions [2,4,6-9] but are consistent with local species loss in areas with direct human impacts and increases in diversity due to invasions and range expansions in lower impact areas. Attempts to detect and understand local biodiversity trends are incomplete without information on local human activities and ecological context

Impact of Reproductive Status and Age on Response of Depressed Women to Cognitive Therapy

Previous research suggests that reproductive hormones are potential affective modulators in mood disorders and may influence response to antidepressant medications. To our knowledge, there are no data on relationships between hormonal status and response to psychotherapy for recurrent major depressive disorder (MDD)

Proof of concept: Partner-Assisted Interpersonal Psychotherapy for perinatal depression

Although poor partner support is a key risk factor for depression in pregnant and postpartum women, partners are not generally involved in treatment beyond psychoeducation. The aim of this "proof of concept" study was to test safety, acceptability, and feasibility of Partner-Assisted Interpersonal Psychotherapy (PA-IPT), an intervention that includes the partner as an active participant throughout treatment. Women more than 12 weeks estimated gestational age and less than 12 weeks postpartum were invited to participate if they fulfilled DSM-IV criteria for Major Depressive Disorder and reported moderate symptom severity (HAM-D17 ≥16). The open trial included eight acute-phase sessions and a 6-week follow-up assessment. Ten couples completed the acute phase treatment and nine presented for a 6-week follow-up assessment. There were no study-related adverse events, and no women had symptomatic worsening from intake to Session Eight. All partners attended all sessions, no couples dropped out of treatment, and all reported positive treatment satisfaction at the conclusion of the study. Nine of ten women (90 %) met the criteria for clinical response (HAM-D17=9) at the conclusion of acute phase treatment, and eight of the nine (89 %) presenting at a 6-week follow-up assessment met criteria for symptomatic recovery. Incorporating partners in the treatment of major depressive disorders during the perinatal period is safe, acceptable, and feasible, but needs further testing in a larger population to evaluate efficacy

An HST/ACS investigation of the spatial and chemical structure and sub-structure of NGC 891, a Milky Way analogue

We present a structural analysis of NGC891, an edge-on galaxy that has long been considered to be an analogue of the Milky Way. Using starcounts derived from deep HST/ACS images, we detect the presence of a thick disk component in this galaxy with vertical scale height 1.44+/-0.03 kpc and radial scale length 4.8+/-0.1 kpc, only slightly longer than that of the thin disk. A stellar spheroid with a de Vaucouleurs-like profile is detected from a radial distance of 0.5 kpc to the edge of the survey at 25 kpc; the structure appears to become more flattened with distance, reaching q = 0.50 in the outermost halo region probed. The halo inside of 15 kpc is moderately metal-rich (median [Fe/H] ~ -1.1) and approximately uniform in median metallicity. Beyond that distance a modest chemical gradient is detected, with the median reaching [Fe/H] ~ -1.3 at 20 kpc. We find evidence for subtle, but very significant, small-scale variations in the median colour and density over the halo survey area. We argue that the colour variations are unlikely to be due to internal extinction or foreground extinction, and reflect instead variations in the stellar metallicity. Their presence suggests a startling conclusion: that the halo of this galaxy is composed of a large number of incompletely-mixed sub-populations, testifying to its origin in a deluge of small accretions.Comment: 21 pages, 16 figures, accepted for publication in MNRA

Optimal column density measurements from multiband near-infrared observations

We consider from a general point of view the problem of determining the extinction in dense molecular clouds. We use a rigorous statistical approach to characterize the properties of the most widely used optical and infrared techniques, namely the star count and the color excess methods. We propose a new maximum-likelihood method that takes advantage of both star counts and star colors to provide an optimal estimate of the extinction. Detailed numerical simulations show that our method performs optimally under a wide range of conditions and, in particular, is significantly superior to the standard techniques for clouds with high column-densities and affected by contamination by foreground stars.Comment: 20 pages; A&A in pres

Radial distribution of stars, gas and dust in SINGS galaxies. I. Surface photometry and morphology

We present ultraviolet through far-infrared surface brightness profiles for the 75 galaxies in the Spitzer Infrared Nearby Galaxies Survey (SINGS). The imagery used to measure the profiles includes GALEX UV data, optical images from KPNO, CTIO and SDSS, near-IR data from 2MASS, and mid- and far-infrared images from Spitzer. Along with the radial profiles, we also provide multi-wavelength asymptotic magnitudes and several non-parametric indicators of galaxy morphology: the concentration index (C_42), the asymmetry (A), the Gini coefficient (G) and the normalized second-order moment of the brightest 20% of the galaxy's flux (M_20). Our radial profiles show a wide range of morphologies and multiple components (bulges, exponential disks, inner and outer disk truncations, etc.) that vary not only from galaxy to galaxy but also with wavelength for a given object. In the optical and near-IR, the SINGS galaxies occupy the same regions in the C_42-A-G-M_20 parameter space as other normal galaxies in previous studies. However, they appear much less centrally concentrated, more asymmetric and with larger values of G when viewed in the UV (due to star-forming clumps scattered across the disk) and in the mid-IR (due to the emission of Polycyclic Aromatic Hydrocarbons at 8.0 microns and very hot dust at 24 microns).Comment: 66 pages in preprint format, 14 figures, published in ApJ. The definitive publisher authenticated version is available online at http://dx.doi.org/10.1088/0004-637X/703/2/156