156 research outputs found

    Signature of Electron Capture in Iron-Rich Ejecta of SN 2003du

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    Late-time near-infrared and optical spectra are presented for the normal-bright SN2003du. At about 300 days after the explosion, the emission profiles of well isolated [FeII] lines (in particular that of the strong 1.644mu feature) trace out the global kinematic distribution of radioactive material in the expanding. In SN2003du, the 1.644 mu [FeII] line shows a flat-topped, profile, indicative of a thick but hollow-centered expanding shell, rather than a strongly-peaked profile that would be expected from a ``center-filled'' distribution.Based on detailed models for exploding Chandrasekhar mass white dwarfs, we show that the feature is consistent with spherical explosion models.Our model predicts central region of non-radioactive electron-capture elements up to 2500--3000km/s as a consequence of burning under high density, and an extended region of 56Ni up to 9,000--10,000km/s. Furthermore our analysis indicates that the 1.644mu [FeII] profile is not consistent with strong mixing between the regions of electron- capture isotopes and the 56Ni layers as is predicted by detailed 3D models for nuclear deflagration fronts. We discuss the possibility that the flat-topped profile could be produced as a result of an infrared catastrophe and conclude that such an explanation is unlikely. We put our results in context to other SNeIa and briefly discuss the implications of our result for the use of SNe Ia as cosmological standard candles.Comment: 12 pages + 8 figures, ApJ (in press, Dec. 20, 2004) For high resolution figures send E-mail to [email protected]

    Nonequilibrium spectral diffusion due to laser heating in stimulated photon echo spectroscopy of low temperature glasses

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    A quantitative theory is developed, which accounts for heating artifacts in three-pulse photon echo (3PE) experiments. The heat diffusion equation is solved and the average value of the temperature in the focal volume of the laser is determined as a function of the 3PE waiting time. This temperature is used in the framework of nonequilibrium spectral diffusion theory to calculate the effective homogeneous linewidth of an ensemble of probe molecules embedded in an amorphous host. The theory fits recently observed plateaus and bumps without introducing a gap in the distribution function of flip rates of the two-level systems or any other major modification of the standard tunneling model.Comment: 10 pages, Revtex, 6 eps-figures, accepted for publication in Phys. Rev.

    Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus.

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    Idiopathic congenital nystagmus is characterized by involuntary, periodic, predominantly horizontal oscillations of both eyes. We identified 22 mutations in FRMD7 in 26 families with X-linked idiopathic congenital nystagmus. Screening of 42 singleton cases of idiopathic congenital nystagmus (28 male, 14 females) yielded three mutations (7%). We found restricted expression of FRMD7 in human embryonic brain and developing neural retina, suggesting a specific role in the control of eye movement and gaze stability

    Extended Slow Phase in Latent/Manifest Latent Nystagmus

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    PURPOSE. To investigate the slow phase in latent/manifest latent nystagmus (LMLN) by producing long eye-drift intervals devoid of fast phases (extended slow phases [ESPs]) and to relate ESP metrics to clinical findings. METHODS. Ten patients with LMLN had eye movements recorded while attending to paired visual and auditory cues presented to their left or right. Patients compared location of the visual target with that of the subsequently heard tone. The auditory cue and the comparison task directed attention away from vision and delayed the fast-phase onset to obtain ESPs. ESP metrics were analyzed with regard to patients' clinical characteristics. Five patients' data were further explored by isolating slow-phase components. RESULTS. All patients exhibited ESPs that resembled the usual slow phase but lasted two to three times longer. Five patients maintained alignment, whereas the other five made vergence movements. Greater eye velocity, excursion, and convergence during an ESP were associated with poor vision and large uncorrected esotropia. These metrics decreased when the viewing eye was in adduction, compared with primary position or abduction. Slow-phase components found in five patients consisted of a dominant decreasing-velocity or linear drift and a low-amplitude periodic oscillation. 1,3 It was suggested therefore that these two nystagmus types be combined into one entity, latent/manifest latent nystagmus (LMLN). CONCLUSIONS. Shifting attention away from vision reliably delays 6 Therefore, characterization of the slow phase is essential for understanding the ocular motor instability in nystagmus. Slow-phase duration is usually short because of its interruption by the fast phase. We searched for a way to modify nystagmus to obtain longer intervals of slow phase that could facilitate its investigation. It has been noticed that after the abolishment of the visual target in the dark the nystagmus cycle becomes less regular, and if a distracting mental task (such as performing mental arithmetic) is added to that, the onset of the fast phase can be delayed (Goldstein HP, et al. IOVS 1992;33: ARVO Abstract 2298-84; Gradstein L, et al. IOVS 1996;37:ARVO Abstract 1030)

    A herbivore tag-and-trace system reveals contact- and density-dependent repellence of a root toxin

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    Foraging behavior of root feeding organisms strongly affects plant-environment-interactions and ecosystem processes. However, the impact of plant chemistry on root herbivore movement in the soil is poorly understood. Here, we apply a simple technique to trace the movement of soil-dwelling insects in their habitats without disturbing or restricting their interactions with host plants. We tagged the root feeding larvae of Melolontha melolontha with a copper ring and repeatedly located their position in relation to their preferred host plant, Taraxacum officinale, using a commercial metal detector. This method was validated and used to study the influence of the sesquiterpene lactone taraxinic acid β-D-glucopyranosyl ester (TA-G) on the foraging of M. melolontha. TA-G is stored in the latex of T. officinale and protects the roots from herbivory. Using behavioral arenas with TA-G deficient and control plants, we tested the impact of physical root access and plant distance on the effect of TA-G on M. melolontha. The larvae preferred TA-G deficient plants to control plants, but only when physical root contact was possible and the plants were separated by 5 cm. Melolontha melolontha showed no preference for TA-G deficient plants when the plants were grown 15 cm apart, which may indicate a trade-off between the cost of movement and the benefit of consuming less toxic food. We demonstrate that M. melolontha integrates host plant quality and distance into its foraging patterns and suggest that plant chemistry affects root herbivore behavior in a plant-density dependent manner. © 2017, Springer Science+Business Media New York

    An exploratory analysis of the impact of family functioning on treatment for depression in adolescents.

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    This article explores aspects of family environment and parent-child conflict that may predict or moderate response to acute treatments among depressed adolescents (N = 439) randomly assigned to fluoxetine, cognitive behavioral therapy, their combination, or placebo. Outcomes were Week 12 scores on measures of depression and global impairment. Of 20 candidate variables, one predictor emerged: Across treatments, adolescents with mothers who reported less parent-child conflict were more likely to benefit than their counterparts. When family functioning moderated outcome, adolescents who endorsed more negative environments were more likely to benefit from fluoxetine. Similarly, when moderating effects were seen on cognitive behavioral therapy conditions, they were in the direction of being less effective among teens reporting poorer family environments

    Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus.

    Get PDF
    Idiopathic congenital nystagmus is characterized by involuntary, periodic, predominantly horizontal oscillations of both eyes. We identified 22 mutations in FRMD7 in 26 families with X-linked idiopathic congenital nystagmus. Screening of 42 singleton cases of idiopathic congenital nystagmus (28 male, 14 females) yielded three mutations (7%). We found restricted expression of FRMD7 in human embryonic brain and developing neural retina, suggesting a specific role in the control of eye movement and gaze stability

    On languages on islands

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    Islands as specific research sites in their own right have been given little direct attention by linguists. The physical segregation, distinctness, and isolation of islands from mainland and continental environments may provide scholars of language with distinct and robust sets of singular and combined case studies for examining the role of islandness in any appreciation of language. Whether distinct and particular sociolinguistic and typological phenomena can be attributable to islands and their islandness and vice versa remains unexplored. This position article considers the possibility of there being anything particular and peculiar about languages spoken on islands as compared to languages spoken on mainlands and continents. It arose out of a workshop titled ‘Exploring island languages’ held at Aarhus University, Denmark on 30 April 2018. The main question posed was: Is there anything special socially, linguistically, grammatically, and typologically about the languages of islands? If so, is it possible to talk about such a thing as an island language?.</p

    Evidence for Type Ia Supernova Diversity from Ultraviolet Observations with the Hubble Space Telescope

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    We present ultraviolet (UV) spectroscopy and photometry of four Type Ia supernovae (SNe 2004dt, 2004ef, 2005M, and 2005cf) obtained with the UV prism of the Advanced Camera for Surveys on the Hubble Space Telescope. This dataset provides unique spectral time series down to 2000 Angstrom. Significant diversity is seen in the near maximum-light spectra (~ 2000--3500 Angstrom) for this small sample. The corresponding photometric data, together with archival data from Swift Ultraviolet/Optical Telescope observations, provide further evidence of increased dispersion in the UV emission with respect to the optical. The peak luminosities measured in uvw1/F250W are found to correlate with the B-band light-curve shape parameter dm15(B), but with much larger scatter relative to the correlation in the broad-band B band (e.g., ~0.4 mag versus ~0.2 mag for those with 0.8 < dm15 < 1.7 mag). SN 2004dt is found as an outlier of this correlation (at > 3 sigma), being brighter than normal SNe Ia such as SN 2005cf by ~0.9 mag and ~2.0 mag in the uvw1/F250W and uvm2/F220W filters, respectively. We show that different progenitor metallicity or line-expansion velocities alone cannot explain such a large discrepancy. Viewing-angle effects, such as due to an asymmetric explosion, may have a significant influence on the flux emitted in the UV region. Detailed modeling is needed to disentangle and quantify the above effects.Comment: 17 pages, 13 figures, accepted by Ap

    ENIGMA-anxiety working group : Rationale for and organization of large-scale neuroimaging studies of anxiety disorders

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    Altres ajuts: Anxiety Disorders Research Network European College of Neuropsychopharmacology; Claude Leon Postdoctoral Fellowship; Deutsche Forschungsgemeinschaft (DFG, German Research Foundation, 44541416-TRR58); EU7th Frame Work Marie Curie Actions International Staff Exchange Scheme grant 'European and South African Research Network in Anxiety Disorders' (EUSARNAD); Geestkracht programme of the Netherlands Organization for Health Research and Development (ZonMw, 10-000-1002); Intramural Research Training Award (IRTA) program within the National Institute of Mental Health under the Intramural Research Program (NIMH-IRP, MH002781); National Institute of Mental Health under the Intramural Research Program (NIMH-IRP, ZIA-MH-002782); SA Medical Research Council; U.S. National Institutes of Health grants (P01 AG026572, P01 AG055367, P41 EB015922, R01 AG060610, R56 AG058854, RF1 AG051710, U54 EB020403).Anxiety disorders are highly prevalent and disabling but seem particularly tractable to investigation with translational neuroscience methodologies. Neuroimaging has informed our understanding of the neurobiology of anxiety disorders, but research has been limited by small sample sizes and low statistical power, as well as heterogenous imaging methodology. The ENIGMA-Anxiety Working Group has brought together researchers from around the world, in a harmonized and coordinated effort to address these challenges and generate more robust and reproducible findings. This paper elaborates on the concepts and methods informing the work of the working group to date, and describes the initial approach of the four subgroups studying generalized anxiety disorder, panic disorder, social anxiety disorder, and specific phobia. At present, the ENIGMA-Anxiety database contains information about more than 100 unique samples, from 16 countries and 59 institutes. Future directions include examining additional imaging modalities, integrating imaging and genetic data, and collaborating with other ENIGMA working groups. The ENIGMA consortium creates synergy at the intersection of global mental health and clinical neuroscience, and the ENIGMA-Anxiety Working Group extends the promise of this approach to neuroimaging research on anxiety disorders
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