Teamworking and the "sharpening" of peripherical vision

Managers and organizations are normally focussed on a number of key issues and targets, such as strategic positioning, operations, competitors, internal processes, human relations, etc. Focus is fundamental to effective exploitation. Focus, however, carries with it some attendant risks. It may, for example, lead to an underestimation of critical moves taking place at the periphery outside the focus of attention. In such instances, peripheral vision becomes crucial to organizational survival. In this paper, we discuss how teams and teamworking may help re-educate attention and in so doing ‘sharpen’ peripheral vision in organizational contexts. A typology is built, which specifies how different types of teams deal with focus and periphery in practice. Next, we discuss the specific cases of the groups that are most oriented towards the periphery to uncover how they manage collective action and collective imagination. The paper finishes with a number of practical suggestions derived from the previous theoretical work. Six strategic practices are critically analyzed: zooming, improvisation, bricolage, scenario thinking, wild cards and weak signals.periphery, peripheral vision, teams, weak signals, minimal structures

The ChIP-seq-defined networks of Bcl-3 gene binding support its required role in skeletal muscle atrophy

NF-kappaB transcriptional activation is required for skeletal muscle disuse atrophy. We are continuing to study how the activation of NF-kB regulates the genes that encode the protein products that cause atrophy. Using ChIP-sequencing we found that Bcl-3, an NF-kB transcriptional activator required for atrophy, binds to the promoters of a number of genes whose collective function describes two major aspects of muscle wasting. By means of bioinformatics analysis of ChIP-sequencing data we found Bcl-3 to be directing transcription networks of proteolysis and energy metabolism. The proteolytic arm of the Bcl-3 networks includes many E3 ligases associated with proteasomal protein degradation, including that of the N-end rule pathway. The metabolic arm appears to be involved in organizing the change from oxidative phosphorylation to glycolysis in atrophying muscle. For one gene, MuRF1, ChIP-sequencing data identified the location of Bcl-3 and p50 binding in the promoter region which directed the creation of deletant and base-substitution mutations of MuRF1 promoter constructs to determine the effect on gene transcription. The results provide the first direct confirmation that the NF-kB binding site is involved in the muscle unloading regulation of MuRF1. Finally, we have combined the ChIP-sequencing results with gene expression microarray data from unloaded muscle to map several direct targets of Bcl-3 that are transcription factors whose own targets describe a set of indirect targets for NF-kB in atrophy. ChIP-sequencing provides the first molecular explanation for the finding that Bcl3 knockout mice are resistant to disuse muscle atrophy. Mapping the transcriptional regulation of muscle atrophy requires an unbiased analysis of the whole genome, which we show is now possible with ChIP-sequencing.R01 AR041705 - NIAMS NIH HHS; R01 AR060217 - NIAMS NIH HHS; AR041705 - NIAMS NIH HHS; AR060217 - NIAMS NIH HH

ROUTINE AS DEVIATION

We draw on evidence scattered across thick descriptions of organizations to outline an alternative model of routine. Instead of defining routine as a process of compliance with prescribed rules and procedures we define it as a process of deviation from the prescribed elements of organizations, resulting from the mutual constitution of repetitive work and improvisation. This view of routine underscores its adaptive nature and suggests that flexibility can be achieved not only by nimble and openly innovative organizations but also by large and organizations engaging in ‘closet’ innovation.

T=0 Partition Functions for Potts Antiferromagnets on Moebius Strips and Effects of Graph Topology

We present exact calculations of the zero-temperature partition function of the $q$-state Potts antiferromagnet (equivalently the chromatic polynomial) for Moebius strips, with width $L_y=2$ or 3, of regular lattices and homeomorphic expansions thereof. These are compared with the corresponding partition functions for strip graphs with (untwisted) periodic longitudinal boundary conditions.Comment: 9 pages, Latex, Phys. Lett. A, in pres

Teamworking and the ‘Sharpening' of Peripheral vision

Managers and organizations are normally focused on a number of key issues and targets, such as strategic positioning, operations, competitors, internal processes, human relations, etc. Focus is fundamental to effective exploitation. Focus, however, carries with it some attendant risks. It may, for example, lead to an underestimation of critical moves taking place at the periphery outside the focus of attention. In such instances, peripheral vision becomes crucial to organizational survival. In this paper, we discuss how teams and teamworking may help re-educate attention and in so doing ‘sharpen’ peripheral vision in organizational contexts. A typology is built, which specifies how different types of teams deal with focus and periphery in practice. Next, we discuss the specific cases of the groups that are most oriented towards the periphery to uncover how they manage collective action and collective imagination. The paper finishes with a number of practical suggestions derived from the previous theoretical work. Six strategic practices are critically analyzed: zooming, improvisation, bricolage, scenario thinking, wild cards and weak signals.N/

Strategy-in-practices : a process philosophical approach to understanding strategy emergence and organizational outcomes

Emergence of a firm’s strategy is of central concern to both Strategy Process (SP) and Strategy-as-Practice (SAP) scholars. While SP scholars view strategy emergence as a long-term macro conditioning process, SAP advocates concentrate on the episodic micro ‘doing’ of strategy actors in formal strategy planning settings. Neither perspective explains satisfactorily how process and practice relate in strategy emergence to produce tangible organizational outcomes. The conundrum of reconciling the macro/micro distinction implied in process and practice stems from a shared Substantialist metaphysical commitment that attributes strategy emergence to substantive entities. In this article, we draw on Process metaphysics and the practice-turn in social philosophy and theory to propose a Strategy-in-Practices (SIP) perspective. SIP emphasizes how the multitude of coping actions taken at the ‘coal-face’ of an organization congeal inadvertently over time into an organizational modus operandi that provides the basis for strategizing. Strategy, therefore, inheres within socio-culturally propagated predispositions that provide the patterned consistency that makes the inadvertent emergence of a coherent strategy possible. By demonstrating how strategy is immanent in socio-culturally propagated practices, the SIP perspective overcomes the troublesome micro/macro distinction implied in SP and SAP research. It also advances our understanding of how strategy emergence impacts organizational outcomes.Publisher PDFPeer reviewe

On the evolution of the inner disk radius with flux in the neutron star low-mass X-ray binary Serpens X-1

We analyze the latest \emph{Suzaku} observation of the bright neutron star low-mass X-ray binary Serpens X-1 taken in 2013 October and 2014 April. The observation was taken using the burst mode and only suffered mild pile-up effects. A broad iron line is clearly detected in the X-ray spectrum. We test different models and find that the iron line is asymmetric and best interpreted by relativistic reflection. The relativistically broadened iron line is generally believed to originate from the innermost regions of the accretion disk, where strong gravity causes a series of special and general relativistic effects. The iron line profile indicates an inner radius of $\sim8$ $R_{\rm G}$, which gives an upper limit on the size of the neutron star. The asymmetric iron line has been observed in a number of previous observations, which gives several inner radius measurements at different flux states. We find that the inner radius of Serpens X-1 does not evolve significantly over the range of $L/L_{\rm Edd}\sim0.4-0.6$, and the lack of flux dependence of the inner radius implies that the accretion disk may be truncated outside the innermost stable circular orbit by the boundary layer rather than the stellar magnetic field.Comment: 8 pages, 6 figures, accepted for publication in Ap

Ensemble candidate classification for the LOTAAS pulsar survey

One of the biggest challenges arising from modern large-scale pulsar surveys is the number of candidates generated. Here, we implemented several improvements to the machine learning (ML) classifier previously used by the LOFAR Tied-Array All-Sky Survey (LOTAAS) to look for new pulsars via filtering the candidates obtained during periodicity searches. To assist the ML algorithm, we have introduced new features which capture the frequency and time evolution of the signal and improved the signal-to-noise calculation accounting for broad profiles. We enhanced the ML classifier by including a third class characterizing RFI instances, allowing candidates arising from RFI to be isolated, reducing the false positive return rate. We also introduced a new training data set used by the ML algorithm that includes a large sample of pulsars misclassified by the previous classifier. Lastly, we developed an ensemble classifier comprised of five different Decision Trees. Taken together these updates improve the pulsar recall rate by 2.5 per cent, while also improving the ability to identify pulsars with wide pulse profiles, often misclassified by the previous classifier. The new ensemble classifier is also able to reduce the percentage of false positive candidates identified from each LOTAAS pointing from 2.5 per cent (∼500 candidates) to 1.1 per cent (∼220 candidates)