Recrutamento e seleção: o caso da Domino's Pizza

Mestrado Bolonha em Gestão de Recursos HumanosHoje em dia, vivemos num mundo muito competitivo e o mercado de trabalho não é exceção, como tal, as organizações para serem bem-sucedidas têm de possuir nos seus quadros os melhores e mais qualificados trabalhadores. Assim sendo, para além de ser necessário investir nas pessoas é crucial investir numa boa equipa de recrutamento e seleção (R&S). O presente TFM consiste num relatório do estágio realizado na empresa Domino’s pizza. O estágio decorreu durante três meses e teve como principal foco a área de R&S. Os principais objetivos do estágio consistiram, não só, em proporcionar um contacto com o contexto empresarial, mas também permitir o desempenho de diversas tarefas na área de Recursos Humanos (RH), com especial ênfase no R&S. A realização do estágio potenciou o desenvolvimento de algumas soft skills, tais como: comunicação, espírito de equipa, excelência na execução das tarefas propostas, sentido crítico, compromisso, integridade, relacionamento profissional e honestidade. O presente relatório é composto por uma revisão da literatura onde é explicado o que é o recrutamento e a seleção, no entanto apresenta um foco maior na área do e-recrutamento que hoje em dia tem uma importância grande nos processos de R&S de qualquer empresa. De seguida serão abordadas todas as atividades desenvolvidas no decorrer do estágio. Por fim será feita uma breve análise crítica confrontando a revisão da literatura com as atividades desenvolvidas na organização.Nowadays, we live in a very competitive world and the job market is no exception, as such, organizations to be successful must have the best and most qualified workers on their staff. Therefore, in addition to investing in people, it is crucial to invest in a good recruitment and selection (R&S) team. The present TFM consists of a report of the internship carried out at the company Domino's pizza. The internship lasted three months and focused on the R&S area. The main objectives of the internship were not only to provide contact with the business context, but also to allow the performance of various tasks in the Human Resources (HR) area, with special emphasis on R&S. The completion of the internship promoted the development of some soft skills, such as: communication, team spirit, excellence in the execution of the proposed tasks, critical thinking, commitment, integrity, professional relationship and honesty. This report is composed of a literature review explaining what recruitment and selection is, however, it presents a greater focus on the area of e-recruitment that nowadays has a great importance in the R&S processes of any company. Next, all the activities developed during the internship will be addressed. Finally, a brief critical analysis will be made comparing the literature review with the activities developed in the organization.info:eu-repo/semantics/publishedVersio

Perfil de susceptibilidade e resultados da associação de antifúngicos: um novo método

Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2010As infecções fúngicas invasivas provocadas por Candida spp. constituem uma importante causa de morbilidade e mortalidade em doentes críticos. Apesar de actualmente estarem disponíveis novos fármacos, como as equinocandinas e os azoles de espectro alargado, que aumentaram as opções terapeuticas, a resistência em ambos os grupos tem sido reportada. A associação de antifúngicos com diferentes mecanismos de acção tem sido utilizada como terapêutica de salvamento, mesmo sem a existência de suporte científico. Os estudos para avaliação destas associações sao escassos, as metodologias propostas sao trabalhosas e morosas e os resultados sao por vezes contraditorios. Neste trabalho, e proposto um protocolo citometrico para avaliar o efeito das associações equinocandinas/anfotericina B e equinocandinas/azoles, sobre espécies de Candida. A susceptibilidade aos antifúngicos, isolados e em associação, foi determinada com recurso a dois marcadores fluorescentes: DiBAC4(3) (anidulafungina/anfotericina B) e FUN-1 (anidulafungina/fluconazole). A soma das razões entre a intensidade de fluorescência das células tratadas com os antifúngicos em associação e a intensidade de fluorescência das células tratadas com o antifúngico isolado, resultou num Índice de fluorescência (IF). Pela correlação com o método clássico foi possível classificar a associação como: antagonista quando IF <1, indiferente quando 1≤ IF ≤2, aditiva quando 2< IF <4 e sinérgica quando IF ≥4. Esta metodologia mostrou uma correlação estatisticamente significativa com os métodos clássicos: checkerboard e determinação de unidades formadoras de colónias. Adicionalmente, revelou ser uma técnica simples e rápida, de elevada sensibilidade e especificidade para detecção de efeitos sinérgicos e antagonistas, mostrando-se uma excelente alternativa no estudo de associações entre antifúngicos. Os casos de antagonismo foram raros, mas o facto de poderem ocorrer independentemente da espécie levam a recomendação da sua avaliação in vitro, previamente a sua prescrição clínica. Assim, encontra-se disponível um novo método para avaliação das associações entre antifúngicos, representando um avanço significativo relativamente às metodologias existentes.Invasive fungal infections caused by Candida spp. represent an important cause of morbidity and mortality in critically ill patients. Although at present novel drugs, such as echinocandins and extended-spectrum azoles, have widened the range of available therapeutic options, resistance to both these groups has been reported. The combination of drugs with different mechanisms of action emerged as a salvage therapy, even though the lack of scientific support. Studies validating such combinations are scarce, and the methods of assessment are laborious, time-consuming, and often provide contradictory results. In the present study a flow cytometric protocol is proposed to evaluate the effect of the combination of echinocandins/amphotericin B and echinocandins/azoles, upon Candida species. The susceptibility to either isolated or combinated antifungals was determined by flow cytometry using two fluorescent markers: DiBAC4(3) (anidulafungin/amphotericin B) and FUN- 1 (anidulafungin/fluconazole). An Index of fluorescence (IF) was calculated, as the sum of ratios between the fluorescence of treated cells with the association of antifungals and the fluorescence of cells treated with each individual antifungal. Comparing to classic method it was possible to categorize the association as antagonistic when IF <1, indifferent when 1≤ IF ≤2, additive when 2< IF <4 and synergic when IF ≥4. This methodology showed an excellent correlation with the classic methods namely, checkerboard assay and the determination of colony forming units. Furthermore, it is a simple and relatively fast assay, providing high sensitivity and specificity for the detection of synergic and antagonistic effects, representing an excellent alternative to assess the effect of antifungal associations. Although antagonism was rarely observed, it may occur independently of species. Therefore it is recommended that antifungal combinations should be evaluated before its clinical use. In conclusion, a new approach is now available for evaluating antifungal combinations, which represents a considerable advance to the classic methodologies

Exploring Nitrogen-Functionalized Graphene Composites for Urinary Catheter Applications

Graphene has been broadly studied, particularly for the fabrication of biomedical devices, owing to its physicochemical and antimicrobial properties. In this study, the antibiofilm efficacy of graphene nanoplatelet (GNP)-based composites as coatings for urinary catheters (UCs) was investigated. GNPs were functionalized with nitrogen (N-GNP) and incorporated into a polydimethylsiloxane (PDMS) matrix. The resulting materials were characterized, and the N-GNP/PDMS composite was evaluated against single- and multi-species biofilms of Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Both biofilm cell composition and structure were analyzed. Furthermore, the antibacterial mechanisms of action of N-GNP were explored. The N-GNP/PDMS composite showed increased hydrophobicity and roughness compared to PDMS. In single-species biofilms, this composite significantly reduced the number of S. aureus, P. aeruginosa, and K. pneumoniae cells (by 64, 41, and 29%, respectively), and decreased S. aureus biofilm culturability (by 50%). In tri-species biofilms, a 41% reduction in total cells was observed. These results are aligned with the outcomes of the biofilm structure analysis. Moreover, N-GNP caused changes in membrane permeability and triggered reactive oxygen species (ROS) synthesis in S. aureus, whereas in Gram-negative bacteria, it only induced changes in cell metabolism. Overall, the N-GNP/PDMS composite inhibited biofilm development, showing the potential of these carbon materials as coatings for UCs. (c) 2023 by the authors

“I Was... Put in a Cage”: The Experience of COVID-19 Home Confinement among Older Adults Living Alone in Portugal*

This article presents findings of a qualitative study reporting older adults' experiences of solitary home confinement during Portugal's first COVID-19 lockdown in 2020. Home confinement was marked by negative experiences, with the exception of one participant who had a particularly favorable combination of resources and circumstances. Negative experiences involved losses in several areas, such as being deprived of out-of-home activities, independence and face-to-face social interactions. Losing out-of-home activi-ties and independence promoted a sense of imprisonment, while losing face-to-face social interactions triggered a feeling of physical loneliness. Considering the potential negative implications of these losses, it is crucial to create innovative solutions that can mitigate them in future lockdowns.info:eu-repo/semantics/publishedVersio

Graphene-Based Coating to Mitigate Biofilm Development in Marine Environments

Due to its several economic and ecological consequences, biofouling is a widely recognized concern in the marine sector. The search for non-biocide-release antifouling coatings has been on the rise, with carbon-nanocoated surfaces showing promising activity. This work aimed to study the impact of pristine graphene nanoplatelets (GNP) on biofilm development through the representative marine bacteria Cobetia marina and to investigate the antibacterial mechanisms of action of this material. For this purpose, a flow cytometric analysis was performed and a GNP/polydimethylsiloxane (PDMS) surface containing 5 wt% GNP (G5/PDMS) was produced, characterized, and assessed regarding its biofilm mitigation potential over 42 days in controlled hydrodynamic conditions that mimic marine environments. Flow cytometry revealed membrane damage, greater metabolic activity, and endogenous reactive oxygen species (ROS) production by C. marina when exposed to GNP 5% (w/v) for 24 h. In addition, C. marina biofilms formed on G5/PDMS showed consistently lower cell count and thickness (up to 43% reductions) than PDMS. Biofilm architecture analysis indicated that mature biofilms developed on the graphene-based surface had fewer empty spaces (34% reduction) and reduced biovolume (25% reduction) compared to PDMS. Overall, the GNP-based surface inhibited C. marina biofilm development, showing promising potential as a marine antifouling coating

Associação entre ingesta de leite materno e desenvolvimento de retinopatia da prematuridade

Purpose: To evaluate the possible protective effect of breast milk against retinopathy of prematurity by comparing the amount of breast milk received by patients who developed retinopathy of prematurity and those who did not and to determine both the required minimum amount of breast milk and the time of life during which neonates need to receive breast milk for this effect to be significant. Methods: Cohort study of newborns with a birth weight of <1500 g or gestational age of <32 weeks, or both, born between January 2011 and October 2014 and hospitalized within the first 24 h of life in the Hospital Criança Conceição Neonatal Intensive Care Unit in Porto Alegre, RS, Brazil. Results: The prevalence of retinopathy of prematurity of any degree was 31% (100 of 323 patients) and that of severe retinopathy of prematurity was of 9% (29 of 323 patients). The median amounts of breast milk received daily by patients with and without retinopathy of prematurity were 4.9 mL/kg (interquartile range, 0.3-15.4) and 10.2 mL/kg (1.5-25.5), respectively. The amount of breast milk received in the first 6 weeks of life was inversely associated with the incidence of both retinopathy of prematurity of any degree and severe retinopathy of prematurity in the univariate analyses. However, the statistical significance was maintained only during the sixth week of life in a per-period multivariate analysis controlling for confounding factors. Conclusions: Small amounts of breast milk are inadequate to prevent retinopathy of prematurity in premature newborns at risk for the disease.Objetivos: Avaliar o possível efeito protetor do leite materno contra a retinopatia da prematuridade, através da comparação da quantidade de leite materno recebida entre os pacientes que desenvolveram retinopatia da prematuridade e aqueles livres da doença. Tentar determinar a quantidade mínima necessária e o momento em que o recém-nascido precisa receber o leite materno para que esse efeito seja significativo. Métodos: Estudo de coorte observacional incluindo recém-nascidos com peso de nascimento inferior a 1500 gramas e/ou com idade gestacional inferior a 32 semanas, nascidos no período de janeiro de 2011 a outubro de 2014 e internados nas primeiras 24 horas de vida na UTI Neonatal do Hospital da Criança Conceição em Porto Alegre. Resultados: A prevalência da retinopatia da prematuridade em qualquer grau foi de 31% (100 casos em 323 pacientes) e a de retinopatia da prematuridade grave foi de 9% (29 casos em 323 pacientes). A mediana da quantidade de leite materno recebida pelos pacientes foi de 10,2 mL/kg/dia entre os pacientes sem retinopatia da prematuridade (amplitude interquartil 1,5-25,5) e de 4,9 mL/kg/dia entre os pacientes com retinopatia da prematuridade (0,3-15,4). A quantidade de leite materno recebida nas primeiras seis semanas de vida foi inversamente associada à incidência de retinopatia da prematuridade em qualquer grau e de retinopatia da prematuridade grave nas análises univariadas, mas a significância estatística não se manteve após análise multivariada para controle de fatores confundidores na maioria dos períodos avaliados, exceto na sexta semana de vida. Conclusão: Pequenas quantidades de leite materno não são suficientes para prevenção de retinopatia da prematuridade em recém-nascidos com de risco para a doença

Worsening of pain and swelling following triamcinolone hexacetonide intra-articular injection: a prospective study in a cohort of patients with rheumatic diseases

Div Rheumatol, São Paulo, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilWeb of Scienc