Using emotions in intelligent virtual environments: the EJaCalIVE framework

Nowadays, there is a need to provide new applications which allow the definition and implementation of safe environments that attends to the user needs and increases their wellbeing. In this sense, this paper introduces the EJaCalIVE framework which allows the creation of emotional virtual environments that incorporate agents, eHealth related devices, human actors, and emotions projecting them virtually and managing the interaction between all the elements. In this way, the proposed framework allows the design and programming of intelligent virtual environments, as well as the simulation and detection of human emotions which can be used for the improvement of the decision-making processes of the developed entities. The paper also shows a case study that enforces the need of this framework in common environments like nursing homes or assisted living facilities. Concretely, the case study proposes the simulation of a residence for the elderly. The main goal is to have an emotion-based simulation to train an assistance robot avoiding the complexity involved in working with the real elders. The main advantage of the proposed framework is to provide a safe environment, that is, an environment where users are able to interact safely with the system.This work is partially supported by the MINECO/FEDER TIN2015-65515-C4-1-R and the FPI Grant AP2013-01276 awarded to Jaime-Andres Rincon. This work is also supported by COMPETE: POCI-01-0145-FEDER-007043 and Fundacao para a Ciencia e Tecnologia (FCT) within the projects UID/CEC/00319/2013 and Post-Doc scholarship SFRH/BPD/102696/2014 (A. Costa).info:eu-repo/semantics/publishedVersio

Using non-invasive wearables for detecting emotions with intelligent agents

This paper proposes the use of intelligent wristbands for the automatic detection of emotional states in order to develop an application which allows to extract, analyze, represent and manage the social emotion of a group of entities. Nowadays, the detection of the joined emotion of an heterogeneous group of people is still an open issue. Most of the existing approaches are centered in the emotion detection and management of a single entity. Concretely, the application tries to detect how music can influence in a positive or negative way over individuals’ emotional states. The main goal of the proposed system is to play music that encourages the increase of happiness of the overall patrons.This work is partially supported by the MINECO/FEDER TIN2015-65515-C4-1-R and the FPI grant AP2013-01276 awarded to Jaime-Andres Rincon. This work is supported by COMPETE: POCI-01-0145-FEDER-007043 and FCT – Fundação para a Ciência e Tecnologia within the projects UID/CEC/00319/2013 and Post-Doc scholarship SFRH/BPD/102696/2014 (A. Cost

ME3CA: A Cognitive Assistant for Physical Exercises that Monitors Emotions and the Environment

[EN] Recent studies show that the elderly population has increased considerably in European society in recent years. This fact has led the European Union and many countries to propose new policies for caring services directed to this group. The current trend is to promote the care of the elderly in their own homes, thus avoiding inverting resources on residences. With this in mind, there are now new solutions in this direction, which try to make use of the continuous advances in computer science. This paper tries to advance in this area by proposing the use of a personal assistant to help older people at home while carrying out their daily activities. The proposed personal assistant is called ME(3)CA, and can be described as a cognitive assistant that offers users a personalised exercise plan for their rehabilitation. The system consists of a sensorisation platform along with decision-making algorithms paired with emotion detection models. ME(3)CA detects the users' emotions, which are used in the decision-making process allowing for more precise suggestions and an accurate (and unbiased) knowledge about the users' opinion towards each exercise.This work was partly supported by the FCT-Fundacao para a Ciencia e Tecnologia through the Post-Doc scholarship SFRH/BPD/102696/2014 (A. Costa), the Generalitat Valenciana (PROMETEO/2018/002) and the Spanish Government (RTI2018-095390-B-C31).Rincon, J.; Araujo, A.; Novais, P.; Julian Inglada, VJ.; Carrascosa Casamayor, C. (2020). ME3CA: A Cognitive Assistant for Physical Exercises that Monitors Emotions and the Environment. Sensors. 20(3):1-14. https://doi.org/10.3390/s20030852S11420

Activities suggestion based on emotions in AAL environments

The elderly population is increasing and the response of the society was to provide them with services directed to them to cope with their needs. One of the oldest solutions is the retirement home, providing housing and permanent assistance for the elderly. Furthermore, most of the retirement homes are inhabited by multiple elderly people, thus creating a community of people who are somewhat related in age and medical issues. The ambient assisted living (AAL) area tries to solve some of the elderly issues by producing technological products, some of them dedicated to elderly homes. One of the identified problem is that elderly people are sometimes discontent about the activities that consume most of their day promoted by the retirement home social workers. The work presented in this paper attempts to improve how these activities are scheduled taking into account the elderlies' emotional response to these activities. The aim is to maximize the group happiness by promoting the activities the group likes, minding if they are bored due to activities repetition. In this sense, this paper presents an extension of the Cognitive Life Assistant platform incorporating a social emotional model. The proposed system has been modelled as a free time activity manager which is in charge of suggesting activities to the social workers. (C) 2018 Elsevier B.V. All rights reserved.Angelo Costa thanks the Fundacao para a Ciencia e a Tecnologia (FCT) the Post-Doc scholarship with the Ref. SFRH/BPD/102696/2014. This work is also supported by COMPETE: POCI-01-0145-FEDER-007043 and FCT - Fundacao para a Ciencia e Tecnologia within the Project Scope: UID/CEC/00319/2013 and partially supported by the MINECO/FEDER TIN2015-65515-C4-1-R and the FPI grant AP2013-01276 awarded to Jaime-Andres Rincon

Towards a cognitive assistant system for elderly

This paper proposes the development of a system to integrally control the activities carried out by a group of elderly people in a nursing home. The system is basically composed of a robot and an app that proposes activities, and also an individual wristband that monitors each elderly person to detect if they get bored or have fun doing the activities. As com-mented, the system also includes an app that, among other things, allows the caregiver to monitor the activities of the group or in an individualized way.GVA - Generalitat Valenciana(PROMETEO/2018/002). e FCT-Fundac¸ao para a Ci ˜ encia e Tecnolog ˆ ´ıa through the Post-Doc scholarship SFRH/BPD/102696/2014 (A. Costa), by the Generalitat Valenciana (PROMETEO/2018/002), by Universitat Politecnica de Valencia research grant (PAID-10-19) and by the Spanish Government (RTI2018-095390-B-C31

programa institucional de Farmacovigilancia en IPS de baja complejidad

Formulario de reporte FOREM INVIMALa farmacovigilancia es fundamental para un sistema de salud, ya que con esta se busca un bienestar a la seguridad de los usuarios, que pueda mejorar su calidad de vida. Con su implementación se puede identificar evaluar, analizar, y tomar decisiones por posibles apariciones de eventos adversos relacionados con el uso de medicamentos con el fin de mitigar alguna acción. En un programa de farmacovigilancia se hace indispensable, la participación del personal de salud y la comunidad. Por esto la importancia de la comunicación cuando se encuentran casos con reacciones adversas con el fin de identificar errores, o uso no correcto de la medicación. Pudiéndose tomar medidas correctivas a tiempo para el bienestar de cada paciente con estas reacciones adversas. Palabra clave: Eficacia de un fármaco, evento adverso, farmacovigilancia INVIMA, ADR, tratamiento farmacológico PMR, medicaciónPharmacovigilance is essential for a health system, with pharmacovigilance it is expected to achieve well-being and the safety of users, in order to improve their quality of life. With its implementation, it is possible to identify, evaluate, analyze, and make decisions for possible occurrences of adverse events related to the use of medications to mitigate any action. In a pharmacovigilance program, the participation of health personnel and the community is essential. For this reason, the importance of communication, if the patient generates adverse reactions to identify errors, or incorrect use of the medication. All this to take corrective measures in time for the well-being of each patient with these adverse reactions. Key word: Efficacy of a drug, adverse event, INVIMA pharmacovigilance, ADR, PMR drug treatment, medication

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial

Background: Short-term treatment for people with type 2 diabetes using a low dose of the selective endothelin A receptor antagonist atrasentan reduces albuminuria without causing significant sodium retention. We report the long-term effects of treatment with atrasentan on major renal outcomes. Methods: We did this double-blind, randomised, placebo-controlled trial at 689 sites in 41 countries. We enrolled adults aged 18–85 years with type 2 diabetes, estimated glomerular filtration rate (eGFR)25–75 mL/min per 1·73 m 2 of body surface area, and a urine albumin-to-creatinine ratio (UACR)of 300–5000 mg/g who had received maximum labelled or tolerated renin–angiotensin system inhibition for at least 4 weeks. Participants were given atrasentan 0·75 mg orally daily during an enrichment period before random group assignment. Those with a UACR decrease of at least 30% with no substantial fluid retention during the enrichment period (responders)were included in the double-blind treatment period. Responders were randomly assigned to receive either atrasentan 0·75 mg orally daily or placebo. All patients and investigators were masked to treatment assignment. The primary endpoint was a composite of doubling of serum creatinine (sustained for ≥30 days)or end-stage kidney disease (eGFR <15 mL/min per 1·73 m 2 sustained for ≥90 days, chronic dialysis for ≥90 days, kidney transplantation, or death from kidney failure)in the intention-to-treat population of all responders. Safety was assessed in all patients who received at least one dose of their assigned study treatment. The study is registered with ClinicalTrials.gov, number NCT01858532. Findings: Between May 17, 2013, and July 13, 2017, 11 087 patients were screened; 5117 entered the enrichment period, and 4711 completed the enrichment period. Of these, 2648 patients were responders and were randomly assigned to the atrasentan group (n=1325)or placebo group (n=1323). Median follow-up was 2·2 years (IQR 1·4–2·9). 79 (6·0%)of 1325 patients in the atrasentan group and 105 (7·9%)of 1323 in the placebo group had a primary composite renal endpoint event (hazard ratio [HR]0·65 [95% CI 0·49–0·88]; p=0·0047). Fluid retention and anaemia adverse events, which have been previously attributed to endothelin receptor antagonists, were more frequent in the atrasentan group than in the placebo group. Hospital admission for heart failure occurred in 47 (3·5%)of 1325 patients in the atrasentan group and 34 (2·6%)of 1323 patients in the placebo group (HR 1·33 [95% CI 0·85–2·07]; p=0·208). 58 (4·4%)patients in the atrasentan group and 52 (3·9%)in the placebo group died (HR 1·09 [95% CI 0·75–1·59]; p=0·65). Interpretation: Atrasentan reduced the risk of renal events in patients with diabetes and chronic kidney disease who were selected to optimise efficacy and safety. These data support a potential role for selective endothelin receptor antagonists in protecting renal function in patients with type 2 diabetes at high risk of developing end-stage kidney disease. Funding: AbbVie

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P &lt; 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

Flexible Agent Architecture: Mixing Reactive and Deliberative Behaviors in SPADE

Over the years, multi-agent systems (MAS) technologies have shown their usefulness in creating distributed applications focused on autonomous intelligent processes. For this purpose, many frameworks for supporting multi-agent systems have been developed, normally oriented towards a particular type of agent architecture (e.g., reactive or deliberative agents). It is common, for example, for a multi-agent platform supporting the BDI (Belief, Desire, Intention) model to provide this agent model exclusively. In most of the existing agent platforms, it is possible to develop either behavior-based agents or deliberative agents based on the BDI cycle, but not both. In this sense, there is a clear lack of flexibility when agents need to perform part of their decision-making process according to the BDI paradigm and, in parallel, require some other behaviors that do not need such a deliberation process. In this context, this paper proposes the introduction of an agent architecture called Flexible Agent Architecture (FAA) that supports the development of multi-agent systems, where each agent can define its actions in terms of different computational models (BDI, procedural, neural networks, etc.) as behaviors, and combine these behaviors as necessary in order to achieve its goals. The FAA architecture has been integrated into a real agent platform, SPADE, thus extending its original capabilities in order to develop applications featuring reactive, deliberative, and hybrid agents. The integration has also adapted the existing facilities of SPADE to all types of behaviors inside agents, for example, the coordination of agents by using a presence notification mechanism, which is a unique feature of SPADE. The resulting SPADE middleware has been used to implement a case study in a simulated robotics scenario, also shown in the paper